Publications by authors named "Charles Craddock"

99Publications

Less Is Not Necessarily More: Toward a Rational Selection of the Conditioning Regimen in Acute Myeloid Leukemia.

J Clin Oncol 2020 Apr 2;38(12):1249-1251. Epub 2020 Mar 2.

Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham, United Kingdom.

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http://dx.doi.org/10.1200/JCO.19.03161DOI Listing
April 2020

The role of allogeneic stem cell transplantation in the management of acute myeloid leukaemia: a triumph of hope and experience.

Br J Haematol 2020 01 10;188(1):129-146. Epub 2019 Dec 10.

Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham, UK.

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http://dx.doi.org/10.1111/bjh.16355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972492PMC
January 2020

Trial re-investment to build better research for better impact.

Lancet 2019 Aug;394(10199):635-636

Department of Haematology, St James's University Hospital, Leeds, LS9 7TF, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(19)31363-7DOI Listing
August 2019

Which patients with acute myeloid leukemia in CR1 can be spared an allogeneic transplant?

Curr Opin Hematol 2019 03;26(2):58-64

Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham, USA.

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http://dx.doi.org/10.1097/MOH.0000000000000482DOI Listing
March 2019

We do still transplant CML, don't we?

Hematology Am Soc Hematol Educ Program 2018 11;2018(1):177-184

Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham, United Kingdom.

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http://dx.doi.org/10.1182/asheducation-2018.1.177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246013PMC
November 2018

Targeting the arginine metabolic brake enhances immunotherapy for leukaemia.

Int J Cancer 2019 10 11;145(8):2201-2208. Epub 2019 Jan 11.

Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1002/ijc.32028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767531PMC
October 2019

CC-486 Maintenance after Stem Cell Transplantation in Patients with Acute Myeloid Leukemia or Myelodysplastic Syndromes.

Biol Blood Marrow Transplant 2018 10 20;24(10):2017-2024. Epub 2018 Jun 20.

Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham, United Kingdom.

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http://dx.doi.org/10.1016/j.bbmt.2018.06.016DOI Listing
October 2018

Current status and future clinical directions in the prevention and treatment of relapse following hematopoietic transplantation for acute myeloid and lymphoblastic leukemia.

Bone Marrow Transplant 2019 01 31;54(1):6-16. Epub 2018 May 31.

Adult Stem Cell Transplant Program, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, 1501 NW 10th Avenue, Suite 916, Miami, FL, 33157, USA.

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http://www.nature.com/articles/s41409-018-0203-8
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http://dx.doi.org/10.1038/s41409-018-0203-8DOI Listing
January 2019

Conditioning intensity in HCT for AML: the jury is still out.

Authors:
Charles Craddock

Lancet Haematol 2018 04 14;5(4):e132-e133. Epub 2018 Mar 14.

Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham B15 2TH, UK. Electronic address:

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http://dx.doi.org/10.1016/S2352-3026(18)30035-8DOI Listing
April 2018

The number of CD56 NK cells in the graft has a major impact on risk of disease relapse following allo-HSCT.

Blood Adv 2017 Aug 21;1(19):1589-1597. Epub 2017 Aug 21.

Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom; and.

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http://dx.doi.org/10.1182/bloodadvances.2017008631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728471PMC
August 2017

Chilli-too hot to handle?

Lancet Oncol 2017 08 26;18(8):1005. Epub 2017 Jul 26.

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http://dx.doi.org/10.1016/S1470-2045(17)30522-3DOI Listing
August 2017

Improving Outcomes in High-Risk Myelodysplasia: Festina Lente.

Authors:
Charles Craddock

J Clin Oncol 2017 08 26;35(24):2729-2731. Epub 2017 May 26.

Charles Craddock, Queen Elizabeth Hospital, Birmingham, and University of Birmingham, Edgbaston, Birmingham, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2017.73.0812DOI Listing
August 2017

Fasting: starving cancer.

Lancet Oncol 2017 04;18(4):431

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http://dx.doi.org/10.1016/S1470-2045(17)30196-1DOI Listing
April 2017

Impact of Alemtuzumab Scheduling on Graft-versus-Host Disease after Unrelated Donor Fludarabine and Melphalan Allografts.

Biol Blood Marrow Transplant 2017 May 14;23(5):805-812. Epub 2017 Feb 14.

Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Northern Centre for Bone Marrow Transplantation, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2017.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588535PMC
May 2017

Association of Macroeconomic Factors With Nonrelapse Mortality After Allogeneic Hematopoietic Cell Transplantation for Adults With Acute Lymphoblastic Leukemia: An Analysis From the Acute Leukemia Working Party of the EBMT.

Oncologist 2016 Mar 11;21(3):377-83. Epub 2016 Feb 11.

Hospital Saint-Antoine, Asistance Publique Hopitaux de Paris, Paris, France European Group for Blood and Marrow Transplantation, Acute Leukemia Working Party Office, Hospital Saint Antoine, Paris, France Universite Pierre et Marie Curie, Paris, France INSERM Unités Mixtes de Recherche 938, Paris, France.

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http://dx.doi.org/10.1634/theoncologist.2015-0314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786353PMC
March 2016

Prediction of Allogeneic Hematopoietic Stem-Cell Transplantation Mortality 100 Days After Transplantation Using a Machine Learning Algorithm: A European Group for Blood and Marrow Transplantation Acute Leukemia Working Party Retrospective Data Mining Study.

J Clin Oncol 2015 Oct 3;33(28):3144-51. Epub 2015 Aug 3.

Roni Shouval, Hila Mishan-Shamay, Avichai Shimoni, and Arnon Nagler, The Chaim Sheba Medical Center, Tel-Hashomer; Roni Shouval, Ori Bondi, and Ron Unger, Bar-Ilan University, Ramat-Gan, Israel; Myriam Labopin, Norbert C. Gorin, Emmanuelle Polge, Arnon Nagler, and Mohamad Mohty, European Group for Blood and Marrow Transplantation; Myriam Labopin and Mohamad Mohty, Sorbonne Universités, Centre de Recherche (CDR) Saint-Antoine; Myriam Labopin and Mohamad Mohty, Institut National de la Santé et de la Recherche Médicale, CDR Saint-Antoine; Myriam Labopin and Mohamad Mohty, Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Antoine, Paris, France; Fabio Ciceri, San Raffaele Scientific Institute, Milan; Andrea Bacigalupo, Ospedale San Martino, Genoa, Italy; Jordi Esteve, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain; Sebastian Giebel, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland; Christoph Schmid, Ludwig-Maximilians-University, Munich; Nicolaus Kroger, University Medical Center Hamburg Eppendorf, Hamburg, Germany; Mahmoud Aljurf, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia; Charles Craddock, Queen Elizabeth Hospital, Birmingham, United Kingdom; Jan J. Cornelissen, Erasmus University Medical Center, Rotterdam, the Netherlands; and Frederic Baron, University of Liège, Liège, Belgium.

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http://jco.ascopubs.org/content/33/28/3144.full.pdf
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.59.1339
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http://dx.doi.org/10.1200/JCO.2014.59.1339DOI Listing
October 2015

Guidelines for the diagnosis and management of acute myeloid leukaemia in pregnancy.

Br J Haematol 2015 Aug 17;170(4):487-95. Epub 2015 Jun 17.

Department of Haematology, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1111/bjh.13554DOI Listing
August 2015

Characterization of CMV-specific CD4+ T-cell reconstitution following stem cell transplantation through the use of HLA Class II-peptide tetramers identifies patients at high risk of recurrent CMV reactivation.

Haematologica 2015 Aug 14;100(8):e318-22. Epub 2015 May 14.

NHS Blood and Transplant, Birmingham, UK School of Cancer Sciences, University of Birmingham, Birmingham, UK Centre for Clinical Haematology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

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http://dx.doi.org/10.3324/haematol.2015.123687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004434PMC
August 2015

Reprint of: Allogeneic hematopoietic cell transplantation for acute myeloid leukemia.

Biol Blood Marrow Transplant 2015 Feb;21(2 Suppl):S3-10

Queen Elizabeth Hospital, Birmingham, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2014.12.032DOI Listing
February 2015

Allogeneic hematopoietic cell transplantation for acute myeloid leukemia.

Biol Blood Marrow Transplant 2015 Jan 13;21(1):8-15. Epub 2014 Nov 13.

Queen Elizabeth Hospital, Birmingham, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2014.10.026DOI Listing
January 2015

Gestational intestinal obstruction complicated by cortical blindness - a multidisciplinary case report.

JRSM Open 2014 Jul 9;5(7):2054270414531120. Epub 2014 Jun 9.

Queen's Hospital, Romford, Rom Valley Way, London RM7 0AG, UK.

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http://dx.doi.org/10.1177/2054270414531120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100233PMC
July 2014

Who is the best hematopoietic stem-cell donor for a male patient with acute leukemia?

Transplantation 2014 Sep;98(5):569-77

1 Center for Allogeneic Stem Cell Transplantation and Division of Therapeutic Immunology, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden. 2 Department of Haematology, Hôpital Saint Antoine, Paris, France. 3 Department of Bone Marrow Transplantation, Essen, University Hospital, Essen, Germany. 4 Medizinische Klinik m. S. Hämatologie/Onkologie, Charité Universitätsmedizin, Berlin, Germany. 5 Medizinische Klinik und Poliklinik I, Universitätsklinikum Dresden, Dresden, Germany. 6 CHU Bordeaux, Hôpital Haut-leveque, Pessac, France. 7 Division of Hematology, Oncology and Hemostasiology, University Hospital Leipzig, Leipzig, Germany. 8 Service Hématologie Greffe de Moelle, Centre Pierre et Marie Curie, Alger, Algeria. 9 Department of Hematology and BMT, Silesian Medical Academy, Katowice, Poland. 10 Department of Hematology/Oncology, Hannover Medical University, Hannover, Germany. 11 Department of Hematology - BMT, Hôpital St. Louis, Paris, France. 12 Department of Hematology/Oncology, University of Münster, Münster, Germany. 13 Division of Hematology, Helsinki University Central Hospital, Helsinki, Finland. 14 Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham, United Kingdom. 15 Address correspondence to: Olle Ringdén, M.D., Ph.D., Karolinska Institutet, Division of Therapeutic Immunology, Karolinska University Hospital Huddinge, F79, SE-141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1097/TP.0000000000000102DOI Listing
September 2014

Stratified medicine in European Medicines Agency licensing: a systematic review of predictive biomarkers.

BMJ Open 2014 Jan 27;4(1):e004188. Epub 2014 Jan 27.

MRC Midland Hub for Trials Methodology Research, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1136/bmjopen-2013-004188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913033PMC
January 2014

Pharmacological methods to reduce disease recurrence.

Authors:
Charles Craddock

Hematology Am Soc Hematol Educ Program 2013 ;2013:63-9

1Queen Elizabeth Hospital, Birmingham, United Kingdom.

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http://dx.doi.org/10.1182/asheducation-2013.1.63DOI Listing
December 2014

Chemokine-mediated tissue recruitment of CXCR3+ CD4+ T cells plays a major role in the pathogenesis of chronic GVHD.

Blood 2012 Nov 25;120(20):4246-55. Epub 2012 Sep 25.

School of Cancer Sciences, University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1182/blood-2012-02-413260DOI Listing
November 2012

Addition of gemtuzumab ozogamicin to induction chemotherapy improves survival in older patients with acute myeloid leukemia.

J Clin Oncol 2012 Nov 30;30(32):3924-31. Epub 2012 Jul 30.

FMedSci, Department of Haematology, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN United Kingdom.

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http://dx.doi.org/10.1200/JCO.2012.42.2964DOI Listing
November 2012

Epigenetic manipulation of the immune response: a novel treatment strategy in hematologic malignancies.

Authors:
Charles Craddock

Cytotherapy 2011 May 7;13(5):516-7. Epub 2011 Mar 7.

Centre for Clinical Haematology, Queen Elizabeth Hospital and School of Cancer Studies, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.3109/14653249.2011.561652DOI Listing
May 2011

Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic leukemia.

Epigenetics 2011 Mar 1;6(3):326-32. Epub 2011 Mar 1.

Medical and Molecular Genetics, Institute of Biomedical Research, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092681PMC
http://dx.doi.org/10.4161/epi.6.3.14404DOI Listing
March 2011

Integrating pharmacogenetics and therapeutic drug monitoring: optimal dosing of imatinib as a case-example.

Eur J Clin Pharmacol 2010 Apr 29;66(4):369-74. Epub 2010 Jan 29.

National Genetics Education and Development Centre, c/o Birmingham Women's Hospital, Edgbaston, UK.

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http://link.springer.com/10.1007/s00228-009-0779-4
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http://dx.doi.org/10.1007/s00228-009-0779-4DOI Listing
April 2010

Molecularly targeted therapy in myeloid leukaemias.

Authors:
Charles Craddock

Clin Med (Lond) 2007 Dec;7(6):632-5

Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954375PMC
http://dx.doi.org/10.7861/clinmedicine.7-6-632DOI Listing
December 2007

CXCL10-CXCR3 interactions play an important role in the pathogenesis of acute graft-versus-host disease in the skin following allogeneic stem-cell transplantation.

Blood 2007 Dec 31;110(12):3827-32. Epub 2007 Aug 31.

Cancer Research United Kingdom Institute for Cancer Studies, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

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http://dx.doi.org/10.1182/blood-2006-12-061408DOI Listing
December 2007

Donor KIR genotype has a major influence on the rate of cytomegalovirus reactivation following T-cell replete stem cell transplantation.

Blood 2006 Feb 20;107(3):1230-2. Epub 2005 Oct 20.

Department of Haematology, University Hospital Birmingham NHS Trust, Edgbaston, Birmingham, United Kingdom.

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http://dx.doi.org/10.1182/blood-2005-03-1039DOI Listing
February 2006