Publications by authors named "Charles A Galea"

20Publications

Characterization of the Polymyxin D Synthetase Biosynthetic Cluster and Product Profile of Paenibacillus polymyxa ATCC 10401.

Authors:
Charles A Galea Meiling Han Yan Zhu Kade Roberts Jiping Wang Philip E Thompson Jian L Tony Velkov

J Nat Prod 2017 05 2;80(5):1264-1274. Epub 2017 May 2.

Monash Biomedicine Discovery Institute, Department of Microbiology, Monash University , Clayton, Victoria 3800, Australia.

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May 2017

Expression and Purification of a Matrix Metalloprotease Transmembrane Domain in Escherichia coli.

Authors:
Charles A Galea

Methods Mol Biol 2017 ;1579:17-33

Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia.

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February 2018

Functional Characterization of the Unique Terminal Thioesterase Domain from Polymyxin Synthetase.

Authors:
Charles A Galea Kade D Roberts Yan Zhu Philip E Thompson Jian Li Tony Velkov

Biochemistry 2017 01 17;56(4):657-668. Epub 2017 Jan 17.

Monash Biomedicine Discovery Institute, Department of Microbiology, Monash University , Parkville, Victoria 3800, Australia.

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January 2017

Compound heterozygous FXN mutations and clinical outcome in friedreich ataxia.

Authors:
Charles A Galea Aamira Huq Paul J Lockhart Geneieve Tai Louise A Corben Eppie M Yiu Lyle C Gurrin David R Lynch Sarah Gelbard Alexandra Durr Francoise Pousset Michael Parkinson Robyn Labrum Paola Giunti Susan L Perlman Martin B Delatycki Marguerite V Evans-Galea

Ann Neurol 2016 Mar;79(3):485-95

Bruce Lefroy Centre, Murdoch Childrens Research Institute, Parkville, Victoria, Australia.

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March 2016

Mutations in RAB39B cause X-linked intellectual disability and early-onset Parkinson disease with α-synuclein pathology.

Authors:
Gabrielle R Wilson Joe C H Sim Catriona McLean Maila Giannandrea Charles A Galea Jessica R Riseley Sarah E M Stephenson Elizabeth Fitzpatrick Stefan A Haas Kate Pope Kirk J Hogan Ronald G Gregg Catherine J Bromhead David S Wargowski Christopher H Lawrence Paul A James Andrew Churchyard Yujing Gao Dean G Phelan Greta Gillies Nicholas Salce Lynn Stanford Ashley P L Marsh Maria L Mignogna Susan J Hayflick Richard J Leventer Martin B Delatycki George D Mellick Vera M Kalscheuer Patrizia D'Adamo Melanie Bahlo David J Amor Paul J Lockhart

Am J Hum Genet 2014 Dec 26;95(6):729-35. Epub 2014 Nov 26.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Melbourne, VIC 3052, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC 3052, Australia. Electronic address:

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December 2014

A potent cyclic peptide targeting SPSB2 protein as a potential anti-infective agent.

Authors:
Beow Keat Yap Eleanor W W Leung Hiromasa Yagi Charles A Galea Sandeep Chhabra David K Chalmers Sandra E Nicholson Philip E Thompson Raymond S Norton

J Med Chem 2014 Aug 6;57(16):7006-15. Epub 2014 Aug 6.

Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University , Parkville 3052, Victoria, Australia.

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August 2014

Beyond loss of frataxin: the complex molecular pathology of Friedreich ataxia.

Authors:
Marguerite V Evans-Galea Paul J Lockhart Charles A Galea Anthony J Hannan Martin B Delatycki

Discov Med 2014 Jan;17(91):25-35

Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Parkville, Victoria 3052, Australia and Department of Paediatrics, The University of Melbourne, Royal Children's Hospital, Parkville, Victoria 3052, Australia.

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January 2014

Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking.

Authors:
Charles A Galea Hai M Nguyen K George Chandy Brian J Smith Raymond S Norton

Cell Mol Life Sci 2014 Apr 3;71(7):1191-210. Epub 2013 Aug 3.

Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, 3052, Australia,

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April 2014

Intracellular trafficking of the KV1.3 potassium channel is regulated by the prodomain of a matrix metalloprotease.

Authors:
Hai M Nguyen Charles A Galea Galina Schmunk Brian J Smith Robert A Edwards Raymond S Norton K George Chandy

J Biol Chem 2013 Mar 8;288(9):6451-64. Epub 2013 Jan 8.

Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, California92697, USA.

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March 2013

Expression and isotopic labelling of the potassium channel blocker ShK toxin as a thioredoxin fusion protein in bacteria.

Authors:
Shih Chieh Chang Charles A Galea Eleanor W W Leung Rajeev B Tajhya Christine Beeton Michael W Pennington Raymond S Norton

Toxicon 2012 Oct 31;60(5):840-50. Epub 2012 May 31.

Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.

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October 2012

Intrinsic protein flexibility in regulation of cell proliferation: advantages for signaling and opportunities for novel therapeutics.

Authors:
Ariele Viacava Follis Charles A Galea Richard W Kriwacki

Adv Exp Med Biol 2012 ;725:27-49

Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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April 2012

A helical conotoxin from Conus imperialis has a novel cysteine framework and defines a new superfamily.

Authors:
Mingyu Ye Keith K Khoo Shaoqiong Xu Mi Zhou Nonlawat Boonyalai Matthew A Perugini Xiaoxia Shao Chengwu Chi Charles A Galea Chunguang Wang Raymond S Norton

J Biol Chem 2012 Apr 7;287(18):14973-83. Epub 2012 Mar 7.

Institute of Protein Research, Tongji University, 1239 Siping Road, Shanghai 20092, China.

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April 2012

Insulin-like growth factor binding protein-2: NMR analysis and structural characterization of the N-terminal domain.

Authors:
Charles A Galea Mehdi Mobli Kerrie A McNeil Terrence D Mulhern John C Wallace Glenn F King Briony E Forbes Raymond S Norton

Biochimie 2012 Mar 22;94(3):608-16. Epub 2011 Sep 22.

Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.

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March 2012

A novel deletion-insertion mutation identified in exon 3 of FXN in two siblings with a severe Friedreich ataxia phenotype.

Authors:
Marguerite V Evans-Galea Louise A Corben Justin Hasell Charles A Galea Michael C Fahey Desirée du Sart Martin B Delatycki

Neurogenetics 2011 Nov 10;12(4):307-13. Epub 2011 Aug 10.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Flemington Road, Parkville, Victoria 3052, Australia.

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November 2011

Large-scale analysis of thermostable, mammalian proteins provides insights into the intrinsically disordered proteome.

Authors:
Charles A Galea Anthony A High John C Obenauer Ashutosh Mishra Cheon-Gil Park Marco Punta Avner Schlessinger Jing Ma Burkhard Rost Clive A Slaughter Richard W Kriwacki

J Proteome Res 2009 Jan;8(1):211-26

Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA.

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January 2009

Regulation of cell division by intrinsically unstructured proteins: intrinsic flexibility, modularity, and signaling conduits.

Authors:
Charles A Galea Yuefeng Wang Sivashankar G Sivakolundu Richard W Kriwacki

Biochemistry 2008 Jul;47(29):7598-609

Department of Structural Biology, St. Jude Children's Research Hospital, 332 North Lauderdale Street, Memphis, Tennessee 38105, USA.

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July 2008

Role of intrinsic flexibility in signal transduction mediated by the cell cycle regulator, p27 Kip1.

Authors:
Charles A Galea Amanda Nourse Yuefeng Wang Sivashankar G Sivakolundu William T Heller Richard W Kriwacki

J Mol Biol 2008 Feb 14;376(3):827-38. Epub 2007 Dec 14.

Department of Structural Biology, St. Jude Children's Research Hospital, 332 North Lauderdale St., Memphis, TN 38105, USA.

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February 2008

Proteomic studies of the intrinsically unstructured mammalian proteome.

Authors:
Charles A Galea Vishwajeeth R Pagala John C Obenauer Cheon-Gil Park Clive A Slaughter Richard W Kriwacki

J Proteome Res 2006 Oct;5(10):2839-48

Department of Structural Biology, St. Jude Children's Research Hospital, and Department of Molecular Sciences, University of Tennessee Health Sciences Center, Memphis, Tennessee 38163, USA.

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October 2006

Thermodynamic characterization of interactions between p27(Kip1) and activated and non-activated Cdk2: intrinsically unstructured proteins as thermodynamic tethers.

Authors:
Prentice Bowman Charles A Galea Eilyn Lacy Richard W Kriwacki

Biochim Biophys Acta 2006 Feb 11;1764(2):182-9. Epub 2006 Jan 11.

Department of Structural Biology, St. Jude Children's Research Hospital, 332 North Lauderdale St., Memphis, TN 38105, USA.

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February 2006

Association of villin with phosphatidylinositol 4,5-bisphosphate regulates the actin cytoskeleton.

Authors:
Narendra Kumar Peilin Zhao Alok Tomar Charles A Galea Seema Khurana

J Biol Chem 2004 Jan 1;279(4):3096-110. Epub 2003 Nov 1.

Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.

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January 2004