Publications by authors named "Charles A Galea"

20Publications

Characterization of the Polymyxin D Synthetase Biosynthetic Cluster and Product Profile of Paenibacillus polymyxa ATCC 10401.

J Nat Prod 2017 05 2;80(5):1264-1274. Epub 2017 May 2.

Monash Biomedicine Discovery Institute, Department of Microbiology, Monash University , Clayton, Victoria 3800, Australia.

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May 2017

Expression and Purification of a Matrix Metalloprotease Transmembrane Domain in Escherichia coli.

Authors:
Charles A Galea

Methods Mol Biol 2017 ;1579:17-33

Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia.

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February 2018

Functional Characterization of the Unique Terminal Thioesterase Domain from Polymyxin Synthetase.

Biochemistry 2017 01 17;56(4):657-668. Epub 2017 Jan 17.

Monash Biomedicine Discovery Institute, Department of Microbiology, Monash University , Parkville, Victoria 3800, Australia.

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January 2017

A potent cyclic peptide targeting SPSB2 protein as a potential anti-infective agent.

J Med Chem 2014 Aug 6;57(16):7006-15. Epub 2014 Aug 6.

Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University , Parkville 3052, Victoria, Australia.

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August 2014

Beyond loss of frataxin: the complex molecular pathology of Friedreich ataxia.

Discov Med 2014 Jan;17(91):25-35

Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Parkville, Victoria 3052, Australia and Department of Paediatrics, The University of Melbourne, Royal Children's Hospital, Parkville, Victoria 3052, Australia.

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January 2014

Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking.

Cell Mol Life Sci 2014 Apr 3;71(7):1191-210. Epub 2013 Aug 3.

Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, 3052, Australia,

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April 2014

Intracellular trafficking of the KV1.3 potassium channel is regulated by the prodomain of a matrix metalloprotease.

J Biol Chem 2013 Mar 8;288(9):6451-64. Epub 2013 Jan 8.

Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, California92697, USA.

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March 2013

Expression and isotopic labelling of the potassium channel blocker ShK toxin as a thioredoxin fusion protein in bacteria.

Toxicon 2012 Oct 31;60(5):840-50. Epub 2012 May 31.

Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.

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October 2012

Intrinsic protein flexibility in regulation of cell proliferation: advantages for signaling and opportunities for novel therapeutics.

Adv Exp Med Biol 2012 ;725:27-49

Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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April 2012

Insulin-like growth factor binding protein-2: NMR analysis and structural characterization of the N-terminal domain.

Biochimie 2012 Mar 22;94(3):608-16. Epub 2011 Sep 22.

Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.

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March 2012

A novel deletion-insertion mutation identified in exon 3 of FXN in two siblings with a severe Friedreich ataxia phenotype.

Neurogenetics 2011 Nov 10;12(4):307-13. Epub 2011 Aug 10.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Flemington Road, Parkville, Victoria 3052, Australia.

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November 2011

Regulation of cell division by intrinsically unstructured proteins: intrinsic flexibility, modularity, and signaling conduits.

Biochemistry 2008 Jul;47(29):7598-609

Department of Structural Biology, St. Jude Children's Research Hospital, 332 North Lauderdale Street, Memphis, Tennessee 38105, USA.

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July 2008

Role of intrinsic flexibility in signal transduction mediated by the cell cycle regulator, p27 Kip1.

J Mol Biol 2008 Feb 14;376(3):827-38. Epub 2007 Dec 14.

Department of Structural Biology, St. Jude Children's Research Hospital, 332 North Lauderdale St., Memphis, TN 38105, USA.

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February 2008

Proteomic studies of the intrinsically unstructured mammalian proteome.

J Proteome Res 2006 Oct;5(10):2839-48

Department of Structural Biology, St. Jude Children's Research Hospital, and Department of Molecular Sciences, University of Tennessee Health Sciences Center, Memphis, Tennessee 38163, USA.

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October 2006

Thermodynamic characterization of interactions between p27(Kip1) and activated and non-activated Cdk2: intrinsically unstructured proteins as thermodynamic tethers.

Biochim Biophys Acta 2006 Feb 11;1764(2):182-9. Epub 2006 Jan 11.

Department of Structural Biology, St. Jude Children's Research Hospital, 332 North Lauderdale St., Memphis, TN 38105, USA.

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February 2006

Association of villin with phosphatidylinositol 4,5-bisphosphate regulates the actin cytoskeleton.

J Biol Chem 2004 Jan 1;279(4):3096-110. Epub 2003 Nov 1.

Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.

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January 2004