Charles A Dinarello

Charles A Dinarello

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Charles A Dinarello

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Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity.

Immunity 2019 Apr;50(4):778-795

IRCCS Humanitas Clinical and Research Center, via Manzoni 56, 20089 Rozzano Milan, Italy; Humanitas University, via Rita Levi Montalcini, 20090 Pieve Emanuele Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.03.012DOI Listing
April 2019

Corrigendum: Anakinra Therapy for Non-cancer Inflammatory Diseases.

Front Pharmacol 2019 8;10:148. Epub 2019 Mar 8.

Department of Medicine, Radboud University Medical Center, Nijmegen, Netherlands.

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https://www.frontiersin.org/article/10.3389/fphar.2019.00148
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http://dx.doi.org/10.3389/fphar.2019.00148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418949PMC
March 2019

Efficacy of canakinumab as first-line biologic agent in adult-onset Still's disease.

Arthritis Res Ther 2019 Feb 13;21(1):54. Epub 2019 Feb 13.

Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Via Olgettina 60, 20132, Milan, Italy.

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http://dx.doi.org/10.1186/s13075-019-1843-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375123PMC
February 2019

Role for nuclear interleukin-37 in the suppression of innate immunity.

Proc Natl Acad Sci U S A 2019 Feb 21. Epub 2019 Feb 21.

Department of Medicine, University of Colorado Denver, Aurora, CO 80045;

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http://dx.doi.org/10.1073/pnas.1821111116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410848PMC
February 2019

Correction to: Efficacy of canakinumab as first-line biologic agent in adult-onset Still's disease.

Arthritis Res Ther 2019 Feb 25;21(1):69. Epub 2019 Feb 25.

Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Via Olgettina 60, 20132, Milan, Italy.

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http://dx.doi.org/10.1186/s13075-019-1850-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388469PMC
February 2019

Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation.

Proc Natl Acad Sci U S A 2019 01 13;116(4):1361-1369. Epub 2018 Dec 13.

The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel;

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http://dx.doi.org/10.1073/pnas.1812266115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347724PMC
January 2019

Treatment of Dilated Cardiomyopathy With Interleukin-1 Inhibition.

Ann Intern Med 2018 Dec 31;169(11):819-820. Epub 2018 Jul 31.

Vita-Salute San Raffaele University and Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele Scientific Institute, Milan, Italy (G.D., C.C., L.D., G.C.).

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http://dx.doi.org/10.7326/L18-0315DOI Listing
December 2018

Anakinra Therapy for Non-cancer Inflammatory Diseases.

Front Pharmacol 2018 6;9:1157. Epub 2018 Nov 6.

Department of Medicine, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.3389/fphar.2018.01157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232613PMC
November 2018

IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake.

Int J Mol Sci 2018 Aug 2;19(8). Epub 2018 Aug 2.

Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Post Zone C7Q, P.O. Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.3390/ijms19082264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121375PMC
August 2018

Interleukin-1α as an intracellular alarmin in cancer biology.

Semin Immunol 2018 08 26;38:3-14. Epub 2018 Oct 26.

The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, 84105, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.smim.2018.10.006DOI Listing
August 2018

Ethanol-mediated suppression of IL-37 licenses alcoholic liver disease.

Liver Int 2018 06 16;38(6):1095-1101. Epub 2017 Dec 16.

Department of Internal Medicine I, Gastroenterology, Endocrinology & Metabolism, Medical University Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1111/liv.13642DOI Listing
June 2018

MABp1 Targeting IL-1α for Moderate to Severe Hidradenitis Suppurativa Not Eligible for Adalimumab: A Randomized Study.

J Invest Dermatol 2018 04 10;138(4):795-801. Epub 2017 Nov 10.

Fourth Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.10.030DOI Listing
April 2018

Role of glutathione metabolism in host defense against infection.

Proc Natl Acad Sci U S A 2018 03 14;115(10):E2320-E2328. Epub 2018 Feb 14.

Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1720833115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877983PMC
March 2018

Biology of IL-38 and its role in disease.

Immunol Rev 2018 01;281(1):191-196

Department of Medicine and Radboud Center for Infectious diseases (RCI), Radboudumc, The Netherlands.

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http://dx.doi.org/10.1111/imr.12612DOI Listing
January 2018

Suppression of inflammation and acquired immunity by IL-37.

Immunol Rev 2018 01;281(1):179-190

Department of Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/imr.12605DOI Listing
January 2018

Overview of the IL-1 family in innate inflammation and acquired immunity.

Immunol Rev 2018 01;281(1):8-27

Department of Medicine, University of Colorado Denver, Aurora, CO, USA.

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http://dx.doi.org/10.1111/imr.12621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756628PMC
January 2018

Introduction to the interleukin-1 family of cytokines and receptors: Drivers of innate inflammation and acquired immunity.

Immunol Rev 2018 01;281(1):5-7

Department of Medicine, University of Colorado, Aurora, CO, USA.

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http://dx.doi.org/10.1111/imr.12624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750395PMC
January 2018

Interleukin-32 in chronic inflammatory conditions is associated with a higher risk of cardiovascular diseases.

Atherosclerosis 2017 Sep 6;264:83-91. Epub 2017 Jul 6.

Department of Internal Medicine, Radboud Center for Infectious Diseases (RCI), Geert Grooteplein Zuid 8, 6525GA Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.07.005DOI Listing
September 2017

Interleukin-37 suppresses the inflammatory response to protect cardiac function in old endotoxemic mice.

Cytokine 2017 07 24;95:55-63. Epub 2017 Feb 24.

Departments of Surgery, University of Colorado Denver, Aurora, CO 80045, USA; Division of Cardiology, the First Affiliated Hospital, Shantou University Medical College, Shantou 515041, China. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2017.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441934PMC
July 2017

IL-18 binding protein reverses the life-threatening hyperinflammation of a baby with the NLRC4 mutation.

J Allergy Clin Immunol 2017 07 28;140(1):316. Epub 2017 Apr 28.

Department of Medicine, University of Colorado Denver, Aurora, Colo.

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http://dx.doi.org/10.1016/j.jaci.2017.02.037DOI Listing
July 2017

Interleukin 37 expression in mice alters sleep responses to inflammatory agents and influenza virus infection.

Neurobiol Sleep Circadian Rhythms 2017 Jun 2;3:1-9. Epub 2016 Dec 2.

Elson S. Floyd College of Medicine, Department of Biomedical Sciences, Washington State University, Spokane, WA, USA 99210-1495.

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https://linkinghub.elsevier.com/retrieve/pii/S24519944163002
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http://dx.doi.org/10.1016/j.nbscr.2016.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218600PMC
June 2017

Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway.

Proc Natl Acad Sci U S A 2017 05 8;114(21):5485-5490. Epub 2017 May 8.

Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1620910114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448210PMC
May 2017

Cytokine Inhibition in Patients With Chronic Fatigue Syndrome: A Randomized Trial.

Ann Intern Med 2017 Apr 7;166(8):557-564. Epub 2017 Mar 7.

From Radboud University Medical Centre, Nijmegen, and University of Amsterdam, Amsterdam, the Netherlands; and University of Colorado Denver, Aurora, Colorado.

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http://dx.doi.org/10.7326/M16-2391DOI Listing
April 2017

IL-1 Inhibition and Vascular Function in CKD.

J Am Soc Nephrol 2017 Mar 19;28(3):971-980. Epub 2016 Sep 19.

Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; and

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http://dx.doi.org/10.1681/ASN.2016040453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328163PMC
March 2017

Alarmins: Feel the Stress.

J Immunol 2017 02;198(4):1395-1402

Faculty of Medicine, Galilee Medical Center, Nahariya Hospital, 22100 Nahariya, Israel

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1601342
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http://dx.doi.org/10.4049/jimmunol.1601342DOI Listing
February 2017

Interleukin-1 Receptor Blockade Rescues Myocarditis-Associated End-Stage Heart Failure.

Front Immunol 2017 9;8:131. Epub 2017 Feb 9.

Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Scientific Institute , Milan , Italy.

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http://dx.doi.org/10.3389/fimmu.2017.00131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298961PMC
February 2017

Interleukin-1 as a mediator of fatigue in disease: a narrative review.

J Neuroinflammation 2017 01 21;14(1):16. Epub 2017 Jan 21.

Department of Internal Medicine, Radboud University Medical Centre, Geert Grooteplein Zuid 8, 6500HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12974-017-0796-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251329PMC
January 2017

α-Linoleic acid enhances the capacity of α-1 antitrypsin to inhibit lipopolysaccharide induced IL-1β in human blood neutrophils.

Mol Med 2016 Dec 4;22:680-693. Epub 2016 Oct 4.

Department of Respiratory Medicine, German Center for Lung Research (DZL), Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.2119/molmed.2016.00119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135082PMC
December 2016

Response of Steroid-Refractory Acute GVHD to α1-Antitrypsin.

Biol Blood Marrow Transplant 2016 09 17;22(9):1596-1601. Epub 2016 May 17.

Fred Hutchinson Cancer Research Center, Seattle, Washington; University of Washington/Seattle Cancer Care Alliance, Seattle, Washington. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10838791163008
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http://dx.doi.org/10.1016/j.bbmt.2016.05.011DOI Listing
September 2016

Treating Life-Threatening Myocarditis by Blocking Interleukin-1.

Crit Care Med 2016 Aug;44(8):e751-4

1Department of Medicine, University of Colorado Denver, Aurora, CO. 2Division of Internal Medicine and Clinical Immunology, IRCCS San Raffaele Scientific Institute, Milan, Italy. 3Division of CardioThoracic Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy. 4Division of Cardiology, IRCCS San Raffaele Scientific Institute, Milan, Italy. 5Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/CCM.0000000000001654DOI Listing
August 2016

Recombinant Human Alpha-1 Antitrypsin-Fc Fusion Protein Reduces Mouse Myocardial Inflammatory Injury After Ischemia-Reperfusion Independent of Elastase Inhibition.

J Cardiovasc Pharmacol 2016 Jul;68(1):27-32

*VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA; †VCU Johnson Research Laboratories, Virginia Commonwealth University, Richmond, VA; ‡Department of Surgery, Virginia Commonwealth University, Richmond, VA; §Department of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University, Richmond, VA; ‖Department of Biomedical Science and Technology, Konkuk University, Seoul, Korea; ¶Department of Medicine, University of Colorado, Denver, CO; and #Department of Experimental Medicine, Radbound University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1097/FJC.0000000000000383DOI Listing
July 2016

Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra.

Ann Rheum Dis 2016 06 14;75(6):1219-27. Epub 2015 Jul 14.

Department of Medicine, University of Colorado Denver, Aurora, Colorado, USA Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands Radboud Institute of Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2014-206966DOI Listing
June 2016

Interleukin-1 Blockade in Acute Decompensated Heart Failure: A Randomized, Double-Blinded, Placebo-Controlled Pilot Study.

J Cardiovasc Pharmacol 2016 Jun;67(6):544-51

*Department of Pharmacotherapy and Outcomes Science, School of Pharmacy, Virginia Commonwealth University, Richmond, VA;†Pauley Heart Center, School of Medicine, Virginia Commonwealth University, Richmond, VA;‡Division of Infectious Diseases, School of Medicine, University of Colorado, Denver, CO;§Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy; and‖Department of AngioCardioNeurology, IRCCS Neuromed, Pozzilli, Italy.

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http://dx.doi.org/10.1097/FJC.0000000000000378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749643PMC
June 2016

Toll-like receptors and chronic inflammation in rheumatic diseases: new developments.

Nat Rev Rheumatol 2016 06 12;12(6):344-57. Epub 2016 May 12.

Department of Internal Medicine, Radboud University Medical Centre, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, Netherlands.

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http://dx.doi.org/10.1038/nrrheum.2016.61DOI Listing
June 2016

Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial.

Crit Care Med 2016 Feb;44(2):275-81

1Division of Rheumatology, Department of Medicine, George Washington University, Washington, DC. 2Department of Critical Care and Pediatrics, University of Pittsburgh Medical Center, Pittsburgh, PA. 3Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL. 4Department of Clinical Research, Temple University, Philadelphia, PA. 5Division of Infectious Diseases, Department of Medicine, University of Colorado Denver, Aurora, CO. 6University of Alabama at Birmingham, Division of Pediatric Rheumatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL. 7Division of Infectious Diseases, Department of Medicine, Brown University, Providence, RI.

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http://dx.doi.org/10.1097/CCM.0000000000001402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378312PMC
February 2016

Inflammation in rheumatology in 2015: New tools to tackle inflammatory arthritis.

Nat Rev Rheumatol 2016 Feb 14;12(2):78-80. Epub 2016 Jan 14.

Department of Medicine, Radboud University Medical Centre, HB 6500 Nijmegen, Netherlands.

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http://dx.doi.org/10.1038/nrrheum.2015.180DOI Listing
February 2016

Beneficial effects of IL-37 after spinal cord injury in mice.

Proc Natl Acad Sci U S A 2016 Feb 19;113(5):1411-6. Epub 2016 Jan 19.

Departament de Biologia Cellular, Fisiologia i Immunologia, Institut de Neurociències, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain;

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http://dx.doi.org/10.1073/pnas.1523212113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747716PMC
February 2016

Autoimmune vitiligo is associated with gain-of-function by a transcriptional regulator that elevates expression of HLA-A*02:01 in vivo.

Proc Natl Acad Sci U S A 2016 Feb 19;113(5):1357-62. Epub 2016 Jan 19.

Human Medical Genetics and Genomics Program, University of Colorado School of Medicine, Aurora, CO 80045; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045;

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http://dx.doi.org/10.1073/pnas.1525001113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747738PMC
February 2016

MHC class II super-enhancer increases surface expression of HLA-DR and HLA-DQ and affects cytokine production in autoimmune vitiligo.

Proc Natl Acad Sci U S A 2016 Feb 19;113(5):1363-8. Epub 2016 Jan 19.

Department of Medicine, University of Colorado School of Medicine, Aurora, CO 80045; Department of Medicine, Radboud University Medical Center, HB6500 Nijmegen, The Netherlands

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http://dx.doi.org/10.1073/pnas.1523482113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747741PMC
February 2016

The role of interleukin-32 against tuberculosis.

Cytokine 2015 Dec 3;76(2):585-587. Epub 2015 Jul 3.

Denver Veterans Affairs Medical Center, 1055 Clermont St, Denver, CO 80206, United States; Departments of Medicine and Academic Affairs, D509, Neustadt Building, National Jewish Health, 1400 Jackson St, Denver, CO 80206, United States; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver Anschutz Medical Campus, 12700 East 19th Avenue, Aurora, CO 80045-2539, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2015.06.013DOI Listing
December 2015

Treating rheumatological diseases and co-morbidities with interleukin-1 blocking therapies.

Rheumatology (Oxford) 2015 Dec 23;54(12):2134-44. Epub 2015 Jul 23.

Department of Medicine, University of Colorado Denver, Aurora, CO, USA, Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://rheumatology.oxfordjournals.org/content/early/2015/07
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http://rheumatology.oxfordjournals.org/content/early/2015/07
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http://www.rheumatology.oxfordjournals.org/lookup/doi/10.109
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http://dx.doi.org/10.1093/rheumatology/kev269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009422PMC
December 2015

IL-1 family members in the pathogenesis and treatment of metabolic disease: Focus on adipose tissue inflammation and insulin resistance.

Cytokine 2015 Oct 17;75(2):280-90. Epub 2015 Jul 17.

Department of Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.cyto.2015.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553099PMC
October 2015

α1-Antitrypsin Combines with Plasma Fatty Acids and Induces Angiopoietin-like Protein 4 Expression.

J Immunol 2015 Oct 11;195(8):3605-16. Epub 2015 Sep 11.

Department of Respiratory Medicine, Hannover Medical School, 30625 Hannover, Germany; Biomedical Research in Endstage and Obstructive Lung Disease Hannover, Member of the German Center for Lung Research, 30626 Hannover, Germany;

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http://dx.doi.org/10.4049/jimmunol.1500740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232844PMC
October 2015

Cytokine inhibition in chronic fatigue syndrome patients: study protocol for a randomized controlled trial.

Trials 2015 Oct 5;16:439. Epub 2015 Oct 5.

Department of Internal Medicine, Radboud University Medical Center, Post Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s13063-015-0971-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595002PMC
October 2015

IL-1 Receptor Antagonist Chimeric Protein: Context-Specific and Inflammation-Restricted Activation.

J Immunol 2015 Aug 8;195(4):1705-12. Epub 2015 Jul 8.

Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel;

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http://www.jimmunol.org/content/195/4/1705.full.pdf
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1501168
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http://dx.doi.org/10.4049/jimmunol.1501168DOI Listing
August 2015

The histone deacetylase inhibitor panobinostat lowers biomarkers of cardiovascular risk and inflammation in HIV patients.

AIDS 2015 Jun;29(10):1195-200

aDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark bDepartment of Medicine, University of Colorado Denver, Aurora, Colorado, USA. *Anne Sofie Høgh Kølbæk Kjær and Christel Rothe Brinkmann contributed equally to the writing of this article.

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http://dx.doi.org/10.1097/QAD.0000000000000678DOI Listing
June 2015

Differential effects of platelets and platelet inhibition by ticagrelor on TLR2- and TLR4-mediated inflammatory responses.

Thromb Haemost 2015 May 26;113(5):1035-45. Epub 2015 Feb 26.

Rahajeng Tunjungputri, MD, Department of Internal Medicine (463), Radboud university medical center, PO Box 9101, 6500 HB Nijmegen, The Netherlands, Tel: +31 24 3618822, Fax: +31 24 3566336, E-mail:

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http://dx.doi.org/10.1160/TH14-07-0579DOI Listing
May 2015

IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction.

Nat Immunol 2015 Apr 2;16(4):354-65. Epub 2015 Mar 2.

1] Ritchie Centre, MIMR-PHI Institute of Medical Research, Melbourne, Victoria, Australia. [2] Department of Paediatrics, Monash University, Melbourne, Australia. [3] Department of Medicine, University of Colorado Denver, Aurora, Colorado, USA.

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http://dx.doi.org/10.1038/ni.3103DOI Listing
April 2015

Treating pulmonary silicosis by blocking interleukin 1.

Am J Respir Crit Care Med 2015 Mar;191(5):596-8

1 University of Colorado Denver Aurora, Colorado and.

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http://dx.doi.org/10.1164/rccm.201412-2150LEDOI Listing
March 2015

ATP-Induced IL-1β Specific Secretion: True Under Stringent Conditions.

Front Immunol 2015 12;6:54. Epub 2015 Feb 12.

Department of Medicine, Radboud University Medical Center, Nijmegen Institute for Infection, Inflammation and Immunity (N4i) , Nijmegen , Netherlands.

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http://dx.doi.org/10.3389/fimmu.2015.00054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325933PMC
March 2015