Publications by authors named "Chaoyi Ma"

8 Publications

  • Page 1 of 1

Current status, crisis and trends in Chinese dental technicians.

Int Dent J 2012 Apr;62(2):79-83

Department of Dental Technology, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Renmin South Road, Chengdu, China.

Background: Chinese dental technicians play a significant role in the globalised market of dental prosthesis fabrication, but this subject has not been investigated in detail. The demand for dental prostheses increases as individuals pay increasing attention to their oral health. Therefore, it is important to investigate the status of Chinese dental technicians.

Objective: To evaluate the current status of Chinese dental technicians.

Methods: Dental technicians' resumés, which reveal information regarding dental technician manpower, degrees, working age and salary, etc., were analysed and compared with those abroad. We also estimated the future demands of dental technician manpower, and discussed some potential solutions.

Results: There are fewer dental technicians in China than in other developed countries; they are also of a lower standard. Male technicians outnumber females. The education level of technicians is insufficient, and the education programme is still in its exploratory stage.

Conclusions: The development of dental technician teams in China represents both an opportunity and a challenge. It is important to move forward from the current situation to yield long-term development. This article provides information on the Chinese dental technology industry, identifies the problems and offers solutions for its development.
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http://dx.doi.org/10.1111/j.1875-595X.2011.00093.xDOI Listing
April 2012

[Feasibility analysis of application of future contract in Chinese materia medica transaction].

Zhongguo Zhong Yao Za Zhi 2011 Aug;36(15):2011-6

Institute of Chinese Materia Medica, Academy of Traditional Chinese Medicine, Beijing 100700, China.

With the rapid development of Chinese economy, the traditional Chinese medicine has been paid more attention worldwide because of its therapeutic effect and the special health care function. The future contract which was born under the modern economic system, by its price discovery function and the circumvention risk function, occupies the main superiority in the commodity exchange. The traditional Chinese medicine, which has a glorious transaction history commodity, whether future contract could be used to carry on the transaction still to lack the scientific examination. This article reviewed traditional Chinese medicine tradition trading mode forms with in the evolution foundation, summarized the Chinese materia medica tradition trading mode characteristic, discussed necessity and feasibility of the future contract as a supplement sale way for traditional Chinese medicine transaction. It also forecasted possible risk of future contract, proposed the preliminary implementation method for traditional Chinese medicine future contract.
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August 2011

Top-geoherbs of traditional Chinese medicine: common traits, quality characteristics and formation.

Front Med 2011 Jun 22;5(2):185-94. Epub 2011 Jun 22.

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

Top-geoherbs used in China are always featured with high qualities, and they grow in specified areas with specific environment. Recently, researches on top-geoherbs have attracted increasing attention in China and other countries. In order to have a thorough knowledge of top-geoherbs, this article reviews the concept, historical evolution, common trait and quality characteristics of top-geoherbs, and explains the forming mechanism including genetic mechanism and environmental mechanism. In addition, it introduces the influence of human factors on the quality of top-geoherbs. Finally, it proposes some problems that should be paid attention to in the researches on top-geoherbs.
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http://dx.doi.org/10.1007/s11684-011-0141-yDOI Listing
June 2011

Paridis saponins inhibiting carcinoma growth and metastasis in vitro and in vivo.

Arch Pharm Res 2011 Jan 6;34(1):43-50. Epub 2011 Apr 6.

School of Pharmaceutical Science and Technology, Tianjin University, China.

Paris polyphylla Smith var. yunnanensis extracts, Rhizoma Paridis saponins (RPS) have been found to show strong antitumor activity. However, few studies have yet investigated pulmonary metastasis treatment with this herb. To detail the effective components in RPS and discuss the preliminary mechanism of antitumor effects in vivo and in vitro, a mixture isolated from RPS was investigated. The main constituents were identified as polyphyllin D, formosanin C, dioscin, Paris H, Paris VII and pennogennin 3-O-α-L-rhamnopyranosyl (1→4)-[β-L-rhamnopyranosyl (1→2)]-β-D-glucopyranoside. In our experiments, LA795 cells were exposed to the mixed compounds. Migration inhibition was evaluated by wound healing assay and migration assay in non-cytotoxic dose which was determined by MTT assay. The results demonstrated that the constituent in varying degrees inhibited the migration of the tumor cells in vitro. The mixture also showed antitumor effects on carcinoma in vivo. In conclusion, the mixture is a potent anticancer agent that elicits programmed cell death and inhibits the migration in murine lung adenocarcinoma, both in vitro and in vivo.
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http://dx.doi.org/10.1007/s12272-011-0105-4DOI Listing
January 2011

Identification of chemical constituents in extracts and rat plasma from Fructus Aurantii by UPLC-PDA-Q-TOF/MS.

Phytochem Anal 2011 Mar-Apr;22(2):112-8. Epub 2011 Jan 24.

School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.

Introduction:  Fructus Aurantii, as a component of several compound formulae, shows many bioactivities. As is well known, the constituents of traditional Chinese medicines are very complex and multiple constituents are responsible for the therapeutic effect. However, the concrete compounds are difficult to confirm. Therefore, studies on the constituents absorbed into serum and their metabolites are necessary.

Objective: To search for the active constituents in Fructus Aurantii.

Methodology: An ultra-performance liquid chromatography-photodiode array detector-quadrupole time-of-flight mass spectrometry (UPLC-PDA-Q-TOF/MS) method was established to analyse the aqueous extract in Fructus Aurantii and the constituents absorbed into blood. Compound identification was made by matching the empirical molecular formula with those of the reported compounds and UV spectra, and further elucidated by lower energy CID mass spectra.

Results: Twelve flavonoid O-glycosides were detected, and nine compounds were tentatively identified as polymethoxylated flavones. Six parent compounds were identified and four metabolites were observed in rat plasma, two of which were identified as naringenin glucuronide and hesperetin glucuronide, respectively.

Conclusion: The approach developed has proved useful in the study of the active constituents in traditional Chinese medicines.
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http://dx.doi.org/10.1002/pca.1252DOI Listing
March 2012

Antitumor and antimetastatic activities of Rhizoma Paridis saponins.

Steroids 2009 Nov-Dec;74(13-14):1051-6. Epub 2009 Aug 20.

School of Pharmaceutical Science and Technology, Tianjin University, Weijin Road, Tianjin, China.

Rhizoma Paridis saponins (RPS) have been found to show strong antitumor activity. However, few studies have yet investigated its role on pulmonary metastasis treated with this herb. To investigate the molecular mechanisms related to metastasis, we studied RPS-treated T739 mice using histopathology, immunohistochemistry and reverse transcription polymerase chain reaction. Apoptosis was measured by TUNEL assay. As a result, RPS inhibited tumor growth by inducing apoptosis and upregulated the expression of TIMP-2 and down-regulated the level of MMP-2 and MMP-9. In conclusion, RPS is a potent anticancer agent that elicits programmed cell death and inhibits metastases in murine lung adenocarcinoma in vivo.
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http://dx.doi.org/10.1016/j.steroids.2009.08.004DOI Listing
February 2010

Characterization of steroidal saponins in saponin extract from Paris polyphylla by liquid chromatography tandem multi-stage mass spectrometry.

Anal Bioanal Chem 2009 Sep 6;395(2):495-505. Epub 2009 Aug 6.

School of Pharmaceutical Science and Technology, Tianjin University, Weijin Road, Tianjin, 300072, China.

Rhizoma Paridis saponins are bioactive steroidal saponins derived from Paris polyphylla. Optimization of the ionization process was performed with electrospray ionization tandem mass spectrometry in both positive and negative-ion modes. Negative-ion ESI was adopted for generation of the precursor deprotonated molecules to achieve the best ionization sensitivity for the analytes. Positive ionization was used to choose the most abundant fragment ion. Furthermore, according to the characteristic fragmentation behavior of known steroidal saponins isolated from this plant (polyphyllin D, formosanin C, gracillin, Paris H, Paris VII, and dioscin), 23 constituents were structurally characterized on the basis of their retention time and ESI analyses, including four pairs of naturally occurring isomers. Five of these 23 constituents were new compounds. The analytical method of LC-MS(n) in positive and negative-ion modes has been developed for the direct structural elucidation of steroid saponins of this kind in plant extracts.
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http://dx.doi.org/10.1007/s00216-009-2987-2DOI Listing
September 2009

Cyclophosphamide promotes pulmonary metastasis on mouse lung adenocarcinoma.

Clin Exp Metastasis 2008 3;25(8):855-64. Epub 2008 Sep 3.

School of Pharmaceutical Science and Technology, Tianjin University, Weijin Road, Tianjin, 300072, China.

Cyclophosphamide (CTX), as a common use of chemotherapeutic agent, has some side effects in clinical treatment. In our experiments, we studied CTX-treated T739 mice using histopathology, immunohistochemistry, reverse transcription polymerase chain reaction and Western blot for markers of proliferation, angiogenesis, tumor progression and distant metastasis. As a result, CTX increased the number and area of metastases and tumor embolus in lungs by effecting on the expression of matrix metalloproteinase-2, intercellular adhesion molecule-1 and tissue inhibitor of metalloproteinase-2. Taken together, it indicated that CTX enhanced the process of pulmonary metastasis by the synergistic effect of matrix-degrading proteases and adhesion proteins.
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http://dx.doi.org/10.1007/s10585-008-9201-3DOI Listing
January 2009