Chantal Dessy

Chantal Dessy

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Chantal Dessy

Chantal Dessy

Publications by authors named "Chantal Dessy"

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MicroRNA-199a-3p and MicroRNA-199a-5p Take Part to a Redundant Network of Regulation of the NOS (NO Synthase)/NO Pathway in the Endothelium.

Arterioscler Thromb Vasc Biol 2018 Oct;38(10):2345-2357

From the Pole of Pharmacology and Therapeutics, Experimental and Clinical Research Institute (IREC), Université catholique de Louvain, Brussels, Belgium (V.J., E.L.G., L.M., H.E., J.-L.B., C.D.).

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http://dx.doi.org/10.1161/ATVBAHA.118.311145DOI Listing
October 2018

Perfusion-decellularization of human ear grafts enables ECM-based scaffolds for auricular vascularized composite tissue engineering.

Acta Biomater 2018 06 11;73:339-354. Epub 2018 Apr 11.

Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain, Avenue Hippocrate 55/B1.55.04, B-1200 Brussels, Belgium; Department of Plastic and Reconstructive Surgery, Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10, B-1200 Brussels, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2018.04.009DOI Listing
June 2018

Bioengineering a Human Face Graft: The Matrix of Identity.

Ann Surg 2017 11;266(5):754-764

*Pole of Morphology, Institute of Experimental and Clinical Research, Université catholique de Louvain, Brussels, Belgium †Pole of Experimental Surgery and Transplantation, Institute of Experimental and Clinical Research, Université catholique de Louvain, Brussels, Belgium ‡Department of Plastic and Reconstructive Surgery, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium §Department for Biomedical Research, University of Bern, Bern, Switzerland ¶Department of Surgery, Section of Transplantation, Wake Forest School of Medicine, Winston-Salem, NC ||Pole of Pharmacology and Therapeutic, Institute of Experimental and Clinical Research, Université catholique de Louvain, Brussels, Belgium **Department of Medical Imaging, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium ††Division of Cell Matrix Biology and Regenerative Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK ‡‡Department of Plastic, Reconstructive and Hand Surgery, Inselspital, University Hospital of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1097/SLA.0000000000002396DOI Listing
November 2017

MRI Assessment of Cardiomyopathy Induced by β1-Adrenoreceptor Autoantibodies and Protection Through β3-Adrenoreceptor Overexpression.

Sci Rep 2017 03 9;7:43951. Epub 2017 Mar 9.

Pole of Pharmacology and Therapeutics (FATH), Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1038/srep43951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343428PMC
March 2017

Nutritional depletion in n-3 PUFA in apoE knock-out mice: A new model of endothelial dysfunction associated with fatty liver disease.

Mol Nutr Food Res 2016 10 1;60(10):2198-2207. Epub 2016 Jun 1.

Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1002/mnfr.201500930DOI Listing
October 2016

Hyaluronidase 1 Deficiency Preserves Endothelial Function and Glycocalyx Integrity in Early Streptozotocin-Induced Diabetes.

Diabetes 2016 09 31;65(9):2742-53. Epub 2016 May 31.

Molecular Physiology Research Unit, Namur Research Institute for Life Sciences, University of Namur, Namur, Belgium.

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http://dx.doi.org/10.2337/db15-1662DOI Listing
September 2016

Effects of BM-573 on Endothelial Dependent Relaxation and Increased Blood Pressure at Early Stages of Atherosclerosis.

PLoS One 2016 28;11(3):e0152579. Epub 2016 Mar 28.

Pole of Pharmacology and Therapeutics (FATH), Institute of Experimental & Clinical Research (IREC), Université Catholique de Louvain (UCL) Medical School, Brussels, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152579PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809599PMC
August 2016

Vascular and Central Activation of Peroxisome Proliferator-Activated Receptor-β Attenuates Angiotensin II-Induced Hypertension: Role of RGS-5.

J Pharmacol Exp Ther 2016 07 27;358(1):151-63. Epub 2016 Apr 27.

Department of Pharmacology, School of Pharmacy (M.R., R.J., M.T., M.G.-G., M.S., M.J.Z., J.D.), and Department of Physiology (I.R.-G.); University of Granada, Granada, Spain; Center for Biomedical Research, Granada, Spain (R.J., J.D.); Pole of Pharmacology and Therapeutics, Institute of Experimental and Clinical Research, School of Medicine, University of Louvain, Brussels, Belgium (E.L.-G., G.R., C.D.); Department of Pharmacology, School of Medicine, University Complutense of Madrid, Madrid, Spain (J.T., F.P.-V.); and Ciber Enfermedades Respiratorias (Ciberes) and Instituto de Investigación Sanitaria Gregorio Marañón (IISGM), Madrid, Spain (F.P.-V.)

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http://dx.doi.org/10.1124/jpet.116.233106DOI Listing
July 2016

Loss of mouse P2Y4 nucleotide receptor protects against myocardial infarction through endothelin-1 downregulation.

J Immunol 2015 Feb 16;194(4):1874-81. Epub 2015 Jan 16.

Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, Université Libre de Bruxelles, 1070 Brussels, Belgium;

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http://dx.doi.org/10.4049/jimmunol.1401364DOI Listing
February 2015

Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.

Circulation 2014 Jan 4;129(4):451-62. Epub 2013 Nov 4.

Institut de Recherche Expérimentale et Clinique (IREC), Pole of Pharmacology and Therapeutics (FATH), Université Catholique de Louvain, Brussels, Belgium (C.B., J. Hammond, E.D.-D., B.M., J. Hamelet, A.M., H.E., K.J., I.L., C.D., J.-L.B.); Pole of Cardiovascular Pathology and Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium (C.B., A.-C.P., L.B.); the Division of Cardiology and Pneumology, University of Goettingen, Goettingen, Germany (K.R.G., V.O.N.); the Department of Cardiovascular Sciences, Katholieke Universiteit Leuven, Belgium (A.V., P.H.); the Department of Medicine and Surgery, University of Salerno and RCCS "Multimedica," Milano, Italy (G.I.); Molecular Cardiology, Medizinische Hochschule Hannover, Germany (D.H.-K.); and Université Paul Sabatier, Inserm UMR 1048 - I2MC, Hôpitaux de Toulouse, France (G.T., D.L.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.004940DOI Listing
January 2014

Different effect of Rho kinase inhibition on calcium signaling in rat isolated large and small arteries.

J Vasc Res 2012 1;49(6):522-33. Epub 2012 Sep 1.

Department of Cellular Physiology, Institute of Neuroscience, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1159/000341230DOI Listing
January 2013

Gene deletion of P2Y4 receptor lowers exercise capacity and reduces myocardial hypertrophy with swimming exercise.

Am J Physiol Heart Circ Physiol 2012 Oct 3;303(7):H835-43. Epub 2012 Aug 3.

Institute of Interdisciplinary Research, Université Libre de Bruxelles, Brussels, Belgium.

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http://dx.doi.org/10.1152/ajpheart.00256.2012DOI Listing
October 2012

P2Y(4) nucleotide receptor: a novel actor in post-natal cardiac development.

Angiogenesis 2012 Sep 22;15(3):349-60. Epub 2012 Mar 22.

Institute of Interdisciplinary Research, IRIBHM, Université Libre de Bruxelles, Building C (5th floor), Campus Erasme, 808 Route de Lennik, 1070, Brussels, Belgium.

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http://dx.doi.org/10.1007/s10456-012-9265-1DOI Listing
September 2012

Vascular hypoxic preconditioning relies on TRPV4-dependent calcium influx and proper intercellular gap junctions communication.

Arterioscler Thromb Vasc Biol 2012 Sep 19;32(9):2241-9. Epub 2012 Jul 19.

Pole of Pharmacology and Therapeutics, Institute of Experimental and Clinical Research, University of Louvain Medical School, 52, Avenue Mounier, B-1200 Brussels, Belgium.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.112.252783
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http://dx.doi.org/10.1161/ATVBAHA.112.252783DOI Listing
September 2012

Vasodilatory mechanisms of beta receptor blockade.

Curr Hypertens Rep 2012 Aug;14(4):310-7

Pole de Pharmacologie et Thérapeutique (FATH), Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain, B01.5309, Avenue Mounier 52, 1200, Brussels, Belgium.

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http://dx.doi.org/10.1007/s11906-012-0278-3DOI Listing
August 2012

Rational design of a fluorescent NADPH derivative imaging constitutive nitric-oxide synthases upon two-photon excitation.

Proc Natl Acad Sci U S A 2012 Jul 16;109(31):12526-31. Epub 2012 Jul 16.

Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, Centre National de la Recherche Scientifique UMR8601, Université Paris Descartes, 75270 Paris, France.

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http://www.pnas.org/content/109/31/12526.full.pdf
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http://www.pnas.org/cgi/doi/10.1073/pnas.1205645109
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http://dx.doi.org/10.1073/pnas.1205645109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411954PMC
July 2012

Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors.

Cancer Res 2012 Feb 19;72(4):939-48. Epub 2011 Dec 19.

Université Catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Pole of Pharmacology, Angiogenesis and Cancer Research Laboratory, Brussels, Belgium.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-2474DOI Listing
February 2012

Moderate caveolin-1 downregulation prevents NADPH oxidase-dependent endothelial nitric oxide synthase uncoupling by angiotensin II in endothelial cells.

Arterioscler Thromb Vasc Biol 2011 Sep 9;31(9):2098-105. Epub 2011 Jun 9.

Pole of Pharmacology and Therapeutics (FATH 5349), Institute of Clinical and Experimental Research, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1161/ATVBAHA.111.230623DOI Listing
September 2011

Delivery of soluble VEGF receptor 1 (sFlt1) by gene electrotransfer as a new antiangiogenic cancer therapy.

Mol Pharm 2011 Jun 13;8(3):701-8. Epub 2011 May 13.

Angiogenesis and Cancer Research Laboratory, Pole of Pharmacology and Therapeutics, Institute of Experimental and Clinical Research, Louvain Drug Research Institute, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1021/mp100268tDOI Listing
June 2011

Beta3-adrenergic receptors in cardiac and vascular tissues emerging concepts and therapeutic perspectives.

Adv Pharmacol 2010 ;59:135-63

Pole of Pharmacology and Therapeutics, Institute of Experimental and Clinical Research, Université catholique de Louvain, Brussels, Belgium.

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https://linkinghub.elsevier.com/retrieve/pii/S10543589105900
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http://dx.doi.org/10.1016/S1054-3589(10)59005-7DOI Listing
November 2010

The regulation of endothelial nitric oxide synthase by caveolin: a paradigm validated in vivo and shared by the 'endothelium-derived hyperpolarizing factor'.

Pflugers Arch 2010 May 26;459(6):817-27. Epub 2010 Mar 26.

Pole of Pharmacology and Therapeutics, Institute of Experimental and Clinical Research, Université catholique de Louvain, UCL-FATH 5349, 52 Avenue E. Mounier, B-1200, Brussels, Belgium.

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http://dx.doi.org/10.1007/s00424-010-0815-3DOI Listing
May 2010

Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis.

J Exp Med 2009 Oct 5;206(11):2381-95. Epub 2009 Oct 5.

Service de Biologie Moléculaire des Ectoparasites, Institut de Biologie et Médecine Moléculaires, Université Libre de Bruxelles, Gosselies B-6041, Belgium.

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http://dx.doi.org/10.1084/jem.20091007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768864PMC
October 2009

Vascular caveolin deficiency supports the angiogenic effects of nitrite, a major end product of nitric oxide metabolism in tumors.

Mol Cancer Res 2009 Jul 30;7(7):1056-63. Epub 2009 Jun 30.

Unit of Pharmacology and Therapeutics, Université Catholique de Louvain, UCL-FATH 5349, Brussels, Belgium.

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http://dx.doi.org/10.1158/1541-7786.MCR-08-0388DOI Listing
July 2009

Impact of cyclic hypoxia on HIF-1alpha regulation in endothelial cells--new insights for anti-tumor treatments.

FEBS J 2009 Jan 10;276(2):509-18. Epub 2008 Dec 10.

Unit of Pharmacology and Therapeutics, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1111/j.1742-4658.2008.06798.xDOI Listing
January 2009

Control of blood pressure variability in caveolin-1-deficient mice: role of nitric oxide identified in vivo through spectral analysis.

Cardiovasc Res 2008 Aug 18;79(3):527-36. Epub 2008 Mar 18.

Unit of Pharmacology and Therapeutics, Université catholique de Louvain, UCL-FATH 5349, Vésale+5, 52 Avenue Mounier, 1200 Brussels, Belgium.

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http://dx.doi.org/10.1093/cvr/cvn080DOI Listing
August 2008

Reciprocal negative regulation between thyrotropin/3',5'-cyclic adenosine monophosphate-mediated proliferation and caveolin-1 expression in human and murine thyrocytes.

Mol Endocrinol 2007 Apr 3;21(4):921-32. Epub 2007 Jan 3.

Institut de Recherche Interdisciplinaire, Campus Erasme, Université Libre de Bruxelles, 808 Route de Lennik, Building C, 1070 Brussels, Belgium.

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http://dx.doi.org/10.1210/me.2006-0328DOI Listing
April 2007

The calcium channel blocker amlodipine promotes the unclamping of eNOS from caveolin in endothelial cells.

Cardiovasc Res 2006 Aug 27;71(3):478-85. Epub 2006 Apr 27.

Unit of Pharmacology and Therapeutics, University of Louvain Medical School, UCL-FATH5349, 53 Avenue E. Mounier, Brussels B-1200, Belgium.

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http://dx.doi.org/10.1016/j.cardiores.2006.04.013DOI Listing
August 2006

Caveolin plays a central role in endothelial progenitor cell mobilization and homing in SDF-1-driven postischemic vasculogenesis.

Circ Res 2006 May 6;98(9):1219-27. Epub 2006 Apr 6.

Unit of Pharmacology and Therapeutics, University of Louvain Medical School, Brussels, Belgium.

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http://dx.doi.org/10.1161/01.RES.0000220648.80170.8bDOI Listing
May 2006

Contribution of oxygenation to BOLD contrast in exercising muscle.

Magn Reson Med 2004 Aug;52(2):391-6

Laboratory of Medicinal Chemistry and Radiopharmacy, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1002/mrm.20155DOI Listing
August 2004

Nitric oxide as a radiosensitizer: evidence for an intrinsic role in addition to its effect on oxygen delivery and consumption.

Int J Cancer 2004 May;109(5):768-73

Laboratory of Medicinal Chemistry and Radiopharmacy, Université Catholique de Louvain, Avenue Mounier 73.40, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1002/ijc.20046DOI Listing
May 2004

Endothelin-1 is a critical mediator of myogenic tone in tumor arterioles: implications for cancer treatment.

Cancer Res 2004 May;64(9):3209-14

University of Louvain Medical School, Unit of Pharmacology and Therapeutics (FATH 5349), Brussels, Belgium.

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May 2004

Changes in Hsp90 expression determine the effects of cyclosporine A on the NO pathway in rat myocardium.

FEBS Lett 2003 Sep;552(2-3):125-9

Department of Biomedical Sciences and Biotechnology, University of Brescia, Brescia, Italy.

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September 2003

Rosuvastatin decreases caveolin-1 and improves nitric oxide-dependent heart rate and blood pressure variability in apolipoprotein E-/- mice in vivo.

Circulation 2003 May 28;107(19):2480-6. Epub 2003 Apr 28.

Department of Medicine, Unit of Pharmacology and Therapeutics, University of Louvain, School of Medicine, Ave Mounier 53, 1200 Brussels, Belgium.

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http://dx.doi.org/10.1161/01.CIR.0000065601.83526.3EDOI Listing
May 2003

Irradiation-induced angiogenesis through the up-regulation of the nitric oxide pathway: implications for tumor radiotherapy.

Cancer Res 2003 Mar;63(5):1012-9

Pharmacology and Therapeutics Unit (FATH 5349), University of Louvain Medical School, B-1200 Brussels, Belgium.

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March 2003

Differential regulation of nitric oxide synthases and their allosteric regulators in heart and vessels of hypertensive rats.

Cardiovasc Res 2003 Feb;57(2):456-67

Unit of Pharmacology and Therapeutics, FATH 5349, Université Catholique de Louvain, 53 Avenue Mounier, B-1200 Brussels, Belgium.

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February 2003

Modulation of the tumor vasculature functionality by ionizing radiation accounts for tumor radiosensitization and promotes gene delivery.

FASEB J 2002 Dec 18;16(14):1979-81. Epub 2002 Oct 18.

University of Louvain Medical School, Pharmacology and Therapeutics Unit (FATH 5349), B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1096/fj.02-0487fjeDOI Listing
December 2002

Chronic hydroxymethylglutaryl coenzyme a reductase inhibition and endothelial function of the normocholesterolemic rat: comparison with angiotensin-converting enzyme inhibition.

J Cardiovasc Pharmacol 2002 Aug;40(2):172-80

Laboratory of Basic Physiology and Pharmacology, ULB/Free University of Brussels, Boulevard du Triomphe CP205/7, B-1050 Brussels, Belgium.

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August 2002