Publications by authors named "Chantal Desdouets"

38Publications

Polyploidy in liver development, homeostasis and disease.

Nat Rev Gastroenterol Hepatol 2020 07 2;17(7):391-405. Epub 2020 Apr 2.

Team Proliferation, Stress and Liver Physiopathology, Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, USPC, Université de Paris, Paris, France.

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July 2020

Hepatospecific ablation of p38α MAPK governs liver regeneration through modulation of inflammatory response to CCl-induced acute injury.

Sci Rep 2019 10 10;9(1):14614. Epub 2019 Oct 10.

Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, USPC, Université Paris Descartes, Université Paris Diderot, Team (Proliferation, Stress and Liver Physiopathology), F-75006, Paris, France.

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October 2019

[Hepatic polyploidy: Dr Jekyll or Mr Hyde].

Med Sci (Paris) 2019 Jun-Jul;35(6-7):519-526. Epub 2019 Jul 5.

Centre de Recherche des Cordeliers, Inserm, Sorbonne Université, USPC, Université Paris Descartes, Université Paris Diderot, équipe Proliferation, Stress and Liver Physiopathology, 15, rue de l'École de Médecine, 75006 Paris, France.

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January 2020

Polyploidy spectrum: a new marker in HCC classification.

Gut 2020 02 12;69(2):355-364. Epub 2019 Apr 12.

Team Proliferation Stress and Liver Physiopathology, Genome and Cancer, Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, USPC, Université Paris Descartes, Université Paris Diderot, Paris, France.

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February 2020

Histone stress: an unexplored source of chromosomal instability in cancer?

Curr Genet 2019 Oct 11;65(5):1081-1088. Epub 2019 Apr 11.

Marseille Cancer Research Centre (CRCM), U1068 Inserm, UMR7258, CNRS, Aix-Marseille Université, Institut Paoli-Calmettes, Equipe labellisée Ligue, Marseille, 13273, France.

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October 2019

Reactive cholangiocytes differentiate into proliferative hepatocytes with efficient DNA repair in mice with chronic liver injury.

J Hepatol 2019 06 20;70(6):1180-1191. Epub 2019 Feb 20.

Laboratory of Hepato-gastroenterology, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium. Electronic address:

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June 2019

Inhibiting Cytokinesis in the Liver: A New Way to Reduce Tumor Development.

Gastroenterology 2018 04 3;154(5):1229-1231. Epub 2018 Mar 3.

Hepatology Program, CIMA-Universidad de Navarra, CIBERehd, Idisna, Pamplona, Spain.

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April 2018

LKB1 as a Gatekeeper of Hepatocyte Proliferation and Genomic Integrity during Liver Regeneration.

Cell Rep 2018 02;22(8):1994-2005

INSERM, U1016, Institut Cochin, Paris, France; CNRS, UMR8104, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France. Electronic address:

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February 2018

Liver physiological polyploidization: MicroRNA-122 a key regulator.

Clin Res Hepatol Gastroenterol 2017 Mar 27;41(2):123-125. Epub 2017 Jan 27.

Inserm, U1016, Institut Cochin, Paris, France; CNRS, UMR 8104, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France. Electronic address:

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March 2017

Liver polyploidy: Dr Jekyll or Mr Hide?

Oncotarget 2015 Apr;6(11):8430-1

Team Cell Cycle and Liver Physopathology. Inserm, U1016, Institut Cochin, Paris, France. CNRS, UMR 8104, Paris, France. Université Paris Descartes, Sorbonne Paris Cité, Paris, France.

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April 2015

Polyploidization in liver tissue.

Am J Pathol 2014 Feb 17;184(2):322-31. Epub 2013 Oct 17.

French Institute of Health and Medical Research (INSERM), U1016, Cochin Institute, Department of Development, Reproduction and Cancer, Paris, France; French National Centre for Scientific Research (CNRS), UMR 8104, Paris, France; Paris Descartes University, Sorbonne Paris Cité, Paris, France. Electronic address:

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February 2014

AMPKα1 controls hepatocyte proliferation independently of energy balance by regulating Cyclin A2 expression.

J Hepatol 2014 Jan 6;60(1):152-9. Epub 2013 Sep 6.

Inserm, U1016, Institut Cochin, Paris, France; CNRS, UMR 8104, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France. Electronic address:

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January 2014

Regulation of the hepatocyte cell cycle: signaling pathways and protein kinases.

Int J Hepatol 2012 26;2012:592354. Epub 2012 Dec 26.

Liver Metabolisms and Cancer, INSERM, UMR 991, Université de Rennes 1, CHU Pontchaillou, 35033 Rennes, France.

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January 2013

Polyploidization without mitosis improves in vivo liver transduction with lentiviral vectors.

Hum Gene Ther 2013 Feb 30;24(2):143-51. Epub 2013 Jan 30.

INSERM UMR-S 948, Université de Nantes, CHU Hôtel Dieu, 44093 Nantes, France.

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February 2013

Hepatocytes polyploidization and cell cycle control in liver physiopathology.

Int J Hepatol 2012 22;2012:282430. Epub 2012 Oct 22.

Division of Cell Cycle, Regeneration and Liver Diseases, EMC Department, Institut Cochin, INSERM U1016, 24 rue du Faubourg Saint Jacques, 75014 Paris, France ; CNRS, UMR8104, Paris, France ; Université Paris Descartes, Sorbonne Paris Cité, Paris, France.

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November 2012