Chang-Seob Seo

Chang-Seob Seo

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Chang-Seob Seo

Chang-Seob Seo

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Safety assessment of Gyejibokryeong-hwan water extract: Study of acute and subacute toxicity, and influence on drug metabolizing enzymes.

J Ethnopharmacol 2019 Aug 12;240:111913. Epub 2019 May 12.

Herbal Medicine Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon, 34054, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03788741183095
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http://dx.doi.org/10.1016/j.jep.2019.111913DOI Listing
August 2019

Analysis and Identification of Active Compounds from Gami-Soyosan Toxic to MCF-7 Human Breast Adenocarcinoma Cells.

Biomolecules 2019 Jul 10;9(7). Epub 2019 Jul 10.

Department of Obstetrics and Gynecology, College of Korean Medicine, Daejeon University, Daejeon 35235, Korea.

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http://dx.doi.org/10.3390/biom9070272DOI Listing
July 2019

Evaluation of the subacute toxicity of Yongdamsagan-tang, a traditional herbal formula, in Crl:CD Sprague Dawley rats.

J Ethnopharmacol 2019 Jun 4;238:111852. Epub 2019 Apr 4.

Herbal Medicine Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03788741183224
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http://dx.doi.org/10.1016/j.jep.2019.111852DOI Listing
June 2019

Modificated Mahuang-Tang, a traditional herbal medicine suppresses inflammatory responses induced by cigarette smoke in human airway epithelial cell and mice.

Phytomedicine 2019 Jun 1;59:152777. Epub 2018 Dec 1.

College of Veterinary Medicine (BK21 Plus Project Team), Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 500-757, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2018.11.037DOI Listing
June 2019

A 4-Week Repeated Oral Dose Toxicity Study of Ssanghwa-Tang in Crl:CD Sprague Dawley Rats.

Evid Based Complement Alternat Med 2019 16;2019:2135351. Epub 2019 May 16.

Herbal Medicine Research Division, Korea Institute of Oriental Medicine, 1672 Yuseongdae-ro, Yuseong-gu, Daejeon 34054, Republic of Korea.

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http://dx.doi.org/10.1155/2019/2135351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541986PMC
May 2019

Ulmus macrocarpa Hance improves benign prostatic hyperplasia by regulating prostatic cell apoptosis.

J Ethnopharmacol 2019 Apr 1;233:115-122. Epub 2018 Dec 1.

Department of Veterinary Pathology, College of Veterinary Medicine, Chungnam National University, Daejeon, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2018.11.042DOI Listing
April 2019

Antidepressant-Like Effects of in a Mouse Model of Reserpine-Induced Depression.

Biomed Res Int 2018 26;2018:5845491. Epub 2018 Jun 26.

Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.

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https://www.hindawi.com/journals/bmri/2018/5845491/
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http://dx.doi.org/10.1155/2018/5845491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038693PMC
January 2019

Effect of Veratrum maackii on Testosterone Propionate-Induced Benign Prostatic Hyperplasia in Rats.

Biol Pharm Bull 2019 Jan 1;42(1):1-9. Epub 2018 Nov 1.

Department of Veterinary Pathology, College of Veterinary Medicine, Chungnam National University.

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http://dx.doi.org/10.1248/bpb.b18-00313DOI Listing
January 2019

Anti-Allergic and Anti-Inflammatory Effects of Kuwanon G and Morusin on MC/9 Mast Cells and HaCaT Keratinocytes.

Molecules 2019 Jan 11;24(2). Epub 2019 Jan 11.

Herbal Medicine Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Korea.

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http://dx.doi.org/10.3390/molecules24020265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359505PMC
January 2019

Quantification of the constituents of the traditional Korea medicine, Samryeongbaekchul-san, and assessment of its antiadipogenic effect.

Saudi Pharm J 2019 Jan 11;27(1):145-153. Epub 2018 Sep 11.

Herbal Medicine Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea.

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http://dx.doi.org/10.1016/j.jsps.2018.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323196PMC
January 2019

Sub-chronic toxicity of Gyejibokryeong-hwan in Sprague-Dawley rats.

J Ethnopharmacol 2018 Oct 18;224:441-450. Epub 2018 Jun 18.

Herbal Medicine Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2018.06.017DOI Listing
October 2018

Safety assessment of Oryeong-san, a traditional herbal formula: Study of subacute toxicity and influence of cytochrome P450s and UDP-glucuronosyltransferases.

Regul Toxicol Pharmacol 2018 Oct 17;98:88-97. Epub 2018 Jul 17.

Herbal Medicine Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon, 34054, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.yrtph.2018.07.010DOI Listing
October 2018

Anti-Obesity Activities of Chikusetsusaponin IVa and L. Seeds.

Nutrients 2018 Sep 3;10(9). Epub 2018 Sep 3.

Herbal Medicine Research Division, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Korea.

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http://www.mdpi.com/2072-6643/10/9/1221
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http://dx.doi.org/10.3390/nu10091221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164478PMC
September 2018

The Inhibitory Effect of Ojeoksan on Early and Advanced Atherosclerosis.

Nutrients 2018 Sep 6;10(9). Epub 2018 Sep 6.

Hanbang Cardio-Renal Syndrome Research Center, Wonkwang University, 460, Iksan-daero, Iksan, Jeonbuk 54538, Korea.

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http://dx.doi.org/10.3390/nu10091256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164175PMC
September 2018

Galgeun-tang Attenuates Cigarette Smoke and Lipopolysaccharide Induced Pulmonary Inflammation via IκBα/NF-κB Signaling.

Molecules 2018 Sep 28;23(10). Epub 2018 Sep 28.

Herbal Medicinal Research Center, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Korea.

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http://dx.doi.org/10.3390/molecules23102489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222390PMC
September 2018

Single Oral Acute Toxicity of Banhasasim-Tang and Its Antiobesity Effect on Diet-Induced Obese Mice and 3T3-L1 Adipocytes.

Evid Based Complement Alternat Med 2018 29;2018:3865434. Epub 2018 Aug 29.

Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.

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https://www.hindawi.com/journals/ecam/2018/3865434/
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http://dx.doi.org/10.1155/2018/3865434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136461PMC
August 2018

Paljung-San, a traditional herbal medicine, attenuates benign prostatic hyperplasia in vitro and in vivo.

J Ethnopharmacol 2018 May 6;218:109-115. Epub 2018 Mar 6.

K-herb Research Center, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2018.02.037DOI Listing
May 2018

Gastroprotective effects of Hwanglyeonhaedok-tang against Helicobacter pylori-induced gastric cell injury.

J Ethnopharmacol 2018 Apr 2;216:239-250. Epub 2018 Feb 2.

Department of Veterinary Pathology, College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea.. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2018.01.025DOI Listing
April 2018

Ethanol Extract of Attenuates Cell Growth through Caspase-Dependent Apoptosis in Benign Prostatic Hyperplasia-1 Cells.

Nutrients 2018 Apr 22;10(4). Epub 2018 Apr 22.

Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Korea.

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http://dx.doi.org/10.3390/nu10040523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946308PMC
April 2018

Potential inhibitory effects of the traditional herbal prescription Hyangso-san against skin inflammation via inhibition of chemokine production and inactivation of STAT1 in HaCaT keratinocytes.

Mol Med Rep 2018 Feb 28;17(2):2515-2522. Epub 2017 Nov 28.

Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Yuseong, Daejeon 34054, Republic of Korea.

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http://www.spandidos-publications.com/10.3892/mmr.2017.8172
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http://dx.doi.org/10.3892/mmr.2017.8172DOI Listing
February 2018

The genotoxicity of an aqueous extract of Gyejibokryeong-hwan.

BMC Complement Altern Med 2018 Jan 22;18(1):21. Epub 2018 Jan 22.

K-herb Research Center, Korea Institute of Oriental Medicine, 1672 Yuseongdae-ro, Yuseong-gu, Daejeon, 305-811, Republic of Korea.

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https://bmccomplementalternmed.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12906-017-2054-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776759PMC
January 2018

Expression of Hepatic Cytochrome P450s in Rats Administered with , a Traditional Herbal Formula.

Pharmacogn Mag 2018 Jan 31;13(Suppl 4):S822-S827. Epub 2018 Jan 31.

KM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.

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http://dx.doi.org/10.4103/pm.pm_107_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822506PMC
January 2018

Simultaneous determination and anti-inflammatory effects of four phenolic compounds in Dendrobii Herba.

Nat Prod Res 2017 Dec 10;31(24):2923-2926. Epub 2017 Mar 10.

a K-herb Research Center, Korea Institute of Oriental Medicine , Daejeon , Republic of Korea.

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https://www.tandfonline.com/doi/full/10.1080/14786419.2017.1
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http://dx.doi.org/10.1080/14786419.2017.1300798DOI Listing
December 2017

Genipin inhibits allergic responses in ovalbumin-induced asthmatic mice.

Int Immunopharmacol 2017 Dec 15;53:49-55. Epub 2017 Oct 15.

College of Veterinary Medicine (BK21 Plus Project Team), Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 61186, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2017.10.010DOI Listing
December 2017

4-Hydroxycinnamic acid protects mice from cigarette smoke-induced pulmonary inflammation via MAPK pathways.

Food Chem Toxicol 2017 Dec 18;110:151-155. Epub 2017 Oct 18.

College of Veterinary Medicine BK21 Plus Project Team, Chonnam National University, Gwangju 61186, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2017.10.027DOI Listing
December 2017

High-efficiency generation of induced pluripotent stem cells from human foreskin fibroblast cells using the Sagunja-tang herbal formula.

BMC Complement Altern Med 2017 Dec 11;17(1):529. Epub 2017 Dec 11.

Mibyeong Research Center, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon, 34054, Republic of Korea.

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http://dx.doi.org/10.1186/s12906-017-2043-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725908PMC
December 2017

A 4-Week Repeated-Dose Oral Toxicity Study of Bojungikgi-Tang in Crl:CD Sprague Dawley Rats.

Evid Based Complement Alternat Med 2017 13;2017:4748904. Epub 2017 Dec 13.

K-Herb Research Center, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea.

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http://dx.doi.org/10.1155/2017/4748904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745664PMC
December 2017

Quantitative Analysis and Biological Efficacies regarding the Neuroprotective and Antineuroinflammatory Actions of the Herbal Formula Jodeungsan in HT22 Hippocampal Cells and BV-2 Microglia.

Evid Based Complement Alternat Med 2017 17;2017:6360836. Epub 2017 Dec 17.

Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.

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http://dx.doi.org/10.1155/2017/6360836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748148PMC
December 2017

Simultaneous Quantification of Eight Marker Compounds in Yongdamsagan-Tang Using a High-Performance Liquid Chromatography Equipped with Photodiode Array Detector.

J Chromatogr Sci 2017 Oct;55(9):926-933

K-herb Research Center, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Korea.

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http://dx.doi.org/10.1093/chromsci/bmx053DOI Listing
October 2017

Yongdamsagan-tang, a traditional herbal formula, inhibits cell growth through the suppression of proliferation and inflammation in benign prostatic hyperplasia epithelial-1 cells.

J Ethnopharmacol 2017 Sep 4;209:230-235. Epub 2017 Aug 4.

K-herb Research Center, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2017.08.002DOI Listing
September 2017

Isoimperatorin attenuates airway inflammation and mucus hypersecretion in an ovalbumin-induced murine model of asthma.

Int Immunopharmacol 2017 Aug 25;49:67-76. Epub 2017 May 25.

Department of Veterinary Pathology, College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2017.05.012DOI Listing
August 2017

Inhibitory effects of Ponciri Fructus on testosterone-induced benign prostatic hyperplasia in rats.

BMC Complement Altern Med 2017 Aug 3;17(1):384. Epub 2017 Aug 3.

K-herb Research Center, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon, 34054, Republic of Korea.

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http://dx.doi.org/10.1186/s12906-017-1877-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543435PMC
August 2017

Genotoxicity evaluation of Hwanglyeonhaedok-tang, an herbal formula.

J Ethnopharmacol 2017 Apr 1;202:122-126. Epub 2016 Dec 1.

K-herb Research Center, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2016.11.051DOI Listing
April 2017

Protective effect of HwangRyunHaeDok-Tang water extract against chronic obstructive pulmonary disease induced by cigarette smoke and lipopolysaccharide in a mouse model.

J Ethnopharmacol 2017 Mar 16;200:60-65. Epub 2017 Feb 16.

College of Veterinary Medicine (BK21 Plus Project Team), Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 500-757, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2017.02.027DOI Listing
March 2017

Exerts Androgenic Activity via Regulation of PSA and KLK2 in 22Rv1 Prostate Cancer Cells.

Pharmacogn Mag 2017 Jan-Mar;13(49):153-158

K-herb Research Center, Korea Institute of Oriental Medicine, Deajeon, Republic of Korea.

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http://dx.doi.org/10.4103/0973-1296.197657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307901PMC
February 2017

Protective Effects of against Cisplatin Nephrotoxicity Both and .

Iran J Pharm Res 2017 ;16(Suppl):197-206

College of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Yusung-gu, Daejeon, South Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963661PMC
January 2017

Protective Effects of Manassantin A against Ethanol-Induced Gastric Injury in Rats.

Biol Pharm Bull 2016 2;39(2):221-9. Epub 2015 Dec 2.

Department of Veterinary Pathology, College of Veterinary Medicine, Chungnam National University.

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http://dx.doi.org/10.1248/bpb.b15-00642DOI Listing
November 2016

Gyeji-tang water extract exerts anti-inflammatory activity through inhibition of ERK and NF-ÎşB pathways in lipopolysaccharide-stimulated RAW 264.7 cells.

BMC Complement Altern Med 2016 Oct 12;16(1):390. Epub 2016 Oct 12.

KM Convergence Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon, 34054, Republic of Korea.

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http://bmccomplementalternmed.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/s12906-016-1366-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062814PMC
October 2016

Ma Huang Tang Suppresses the Production and Expression of Inflammatory Chemokines via Downregulating STAT1 Phosphorylation in HaCaT Keratinocytes.

Evid Based Complement Alternat Med 2016 26;2016:7831291. Epub 2016 Oct 26.

Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea; Korean Medicine Life Science, University of Science & Technology, Daejeon 34113, Republic of Korea.

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http://dx.doi.org/10.1155/2016/7831291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101387PMC
October 2016

Expression of Cytochrome P450s in the Liver of Rats Administered with Socheongryong-tang, a Traditional Herbal Formula.

Pharmacogn Mag 2016 Jul-Sep;12(47):211-8

KM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of Korea.

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http://www.phcog.com/text.asp?2016/12/47/211/186340
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http://dx.doi.org/10.4103/0973-1296.186340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989797PMC
September 2016

Acute and subacute toxicity of an ethanolic extract of Melandrii Herba in Crl:CD sprague dawley rats and cytotoxicity of the extract in vitro.

BMC Complement Altern Med 2016 Sep 22;16(1):370. Epub 2016 Sep 22.

K-herb Research Center, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon, 34054, Republic of Korea.

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http://bmccomplementalternmed.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/s12906-016-1342-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034513PMC
September 2016

Inhibitory Effect of Yongdamsagan-Tang Water Extract, a Traditional Herbal Formula, on Testosterone-Induced Benign Prostatic Hyperplasia in Rats.

Evid Based Complement Alternat Med 2016 18;2016:1428923. Epub 2016 Jul 18.

K-herb Research Center, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea.

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http://www.hindawi.com/journals/ecam/2016/1428923/
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http://dx.doi.org/10.1155/2016/1428923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967681PMC
August 2016

Vascular Protective Role of Samul-Tang in HUVECs: Involvement of Nrf2/HO-1 and NO.

Evid Based Complement Alternat Med 2016 5;2016:9580234. Epub 2016 Jun 5.

College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Republic of Korea; Hanbang Body-Fluid Research Center, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Republic of Korea.

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http://dx.doi.org/10.1155/2016/9580234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913014PMC
July 2016

Chondroprotective and anti-inflammatory effects of ChondroT, a new complex herbal medication.

BMC Complement Altern Med 2016 Jul 13;16:213. Epub 2016 Jul 13.

College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju, 500-757, Republic of Korea.

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http://dx.doi.org/10.1186/s12906-016-1211-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944440PMC
July 2016

Anti-inflammatory effect and action mechanisms of traditional herbal formula Gamisoyo-san in RAW 264.7 macrophages.

BMC Complement Altern Med 2016 Jul 15;16:219. Epub 2016 Jul 15.

KM Convergence Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon, 34054, Republic of Korea.

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http://dx.doi.org/10.1186/s12906-016-1197-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946171PMC
July 2016

Anti‑inflammatory and antioxidant activity of the traditional herbal formula Gwakhyangjeonggi‑san via enhancement of heme oxygenase‑1 expression in RAW264.7 macrophages.

Mol Med Rep 2016 May 4;13(5):4365-71. Epub 2016 Apr 4.

K‑herb Research Center, Korea Institute of Oriental Medicine, Daejeon, Chungcheong 34054, Republic of Korea.

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http://dx.doi.org/10.3892/mmr.2016.5084DOI Listing
May 2016

Elsholtzia ciliata (Thunb.) Hylander attenuates renal inflammation and interstitial fibrosis via regulation of TGF-Ăź and Smad3 expression on unilateral ureteral obstruction rat model.

Phytomedicine 2016 Apr 11;23(4):331-9. Epub 2016 Feb 11.

College of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon, 305-764, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09447113160003
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http://dx.doi.org/10.1016/j.phymed.2016.01.013DOI Listing
April 2016

Quantitative Analysis and In vitro Anti-inflammatory Effects of Gallic Acid, Ellagic Acid, and Quercetin from Radix Sanguisorbae.

Pharmacogn Mag 2016 Apr-Jun;12(46):104-8

K-Herb Research Center, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea.

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http://dx.doi.org/10.4103/0973-1296.177908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809163PMC
April 2016

HPLC-PDA Method for Simultaneous Determination of Nine Marker Components in Banhasasim-Tang.

J Chromatogr Sci 2016 Mar 8;54(3):299-304. Epub 2015 Sep 8.

K-herb Research Center, Korea Institute of Oriental Medicine, 1672 Yuseongdae-ro, Yuseong-gu, Daejeon 34054, Korea

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http://dx.doi.org/10.1093/chromsci/bmv141DOI Listing
March 2016

meso-Dihydroguaiaretic acid attenuates airway inflammation and mucus hypersecretion in an ovalbumin-induced murine model of asthma.

Int Immunopharmacol 2016 Feb 11;31:239-47. Epub 2016 Jan 11.

Department of Veterinary Pathology, College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2015.12.033DOI Listing
February 2016

Anti-allergic effects of sesquiterpene lactones from the root of Aucklandia lappa Decne.

Mol Med Rep 2015 Nov 21;12(5):7789-95. Epub 2015 Sep 21.

K-herb Research Center, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.

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https://www.spandidos-publications.com/10.3892/mmr.2015.4342
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http://dx.doi.org/10.3892/mmr.2015.4342DOI Listing
November 2015

Safety assessment of Guibi-tang: Subchronic toxicity study in Crl:CD SD rats.

Regul Toxicol Pharmacol 2015 Nov 30;73(2):485-93. Epub 2015 Sep 30.

Herbal Medicine Formulation Research Group, Korea Institute of Oriental Medicine, 483 Expo-ro, Yuseong-gu, Daejeon 305-811, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.yrtph.2015.09.030DOI Listing
November 2015

Quality Assessment of Ojeok-San, a Traditional Herbal Formula, Using High-Performance Liquid Chromatography Combined with Chemometric Analysis.

J Anal Methods Chem 2015 11;2015:607252. Epub 2015 Oct 11.

Herbal Medicine Formulation Research Group, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of Korea.

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http://dx.doi.org/10.1155/2015/607252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619932PMC
November 2015

Chungsimyeonja-eum inhibits inflammatory responses in RAW 264.7 macrophages and HaCaT keratinocytes.

BMC Complement Altern Med 2015 Oct 16;15:371. Epub 2015 Oct 16.

Korean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, 34054, Republic of Korea.

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http://dx.doi.org/10.1186/s12906-015-0902-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609053PMC
October 2015

Traditional Korean Herbal Formula Samsoeum Attenuates Adipogenesis by Regulating the Phosphorylation of ERK1/2 in 3T3-L1 Cells.

Evid Based Complement Alternat Med 2015 21;2015:893934. Epub 2015 Sep 21.

K-Herb Research Center, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of Korea.

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http://dx.doi.org/10.1155/2015/893934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592915PMC
October 2015

Phytochemical Analysis on Quantification and the Inhibitory Effects on Inflammatory Responses from the Fruit of Xanthii fructus.

Pharmacogn Mag 2015 Oct;11(Suppl 4):S585-91

KM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea; Korean Medicine Life Science, University of Science and Technology, Daejeon, Republic of Korea.

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http://dx.doi.org/10.4103/0973-1296.172966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787093PMC
October 2015

Quantitative analysis and anti-inflammatory effects of Gleditsia sinensis thorns in RAW 264.7 macrophages and HaCaT keratinocytes.

Mol Med Rep 2015 Sep 16;12(3):4773-4781. Epub 2015 Jun 16.

K-herb Research Center, Korea Institute of Oriental Medicine, Daejeon 305‑811, Republic of Korea.

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http://dx.doi.org/10.3892/mmr.2015.3936DOI Listing
September 2015

Traditional medicine yanggyuksanhwa-tang inhibits adipogenesis and suppresses proliferator-activated receptor-gamma expression in 3T3-L1 cells.

Pharmacogn Mag 2015 Jul-Sep;11(43):502-8

Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.

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http://dx.doi.org/10.4103/0973-1296.160456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522835PMC
August 2015

Simultaneous determination of nine marker compounds in the traditional Korean medicine, Dangguisu-san by high-performance liquid chromatography.

Pharmacogn Mag 2015 Jul-Sep;11(43):555-61

Herbal Medicine Formulation Research Group, Herbal Medicine Research Division, Korea Institute, 1672 Yuseongdae-ro, Yuseong-gu, Daejeon, 305-811, Republic of Korea.

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http://dx.doi.org/10.4103/0973-1296.160457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522842PMC
August 2015

Simultaneous determination of three sesquiterpene lactones in Aucklandia lappa Decne by high-performance liquid chromatography.

Pharmacogn Mag 2015 Jul-Sep;11(43):562-6

K-herb Research Center, Korea Institute of Oriental Medicine, 1672 Yuseongdae-ro, Yuseong-gu, Daejeon 305-811, Republic of Korea.

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http://dx.doi.org/10.4103/0973-1296.160471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522843PMC
August 2015

Anti-adipogenic and antioxidant effects of the traditional Korean herbal formula Samchulgeonbi-tang: an in vitro study.

Int J Clin Exp Med 2015 15;8(6):8698-708. Epub 2015 Jun 15.

KM Convergence Research Division, Korea Institute of Oriental Medicine Daejeon, Republic of Korea.

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August 2015

Extracts of Scutellariae Radix inhibit low-density lipoprotein oxidation and the lipopolysaccharide-induced macrophage inflammatory response.

Mol Med Rep 2015 Jul 17;12(1):1335-41. Epub 2015 Mar 17.

Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Yuseong‑gu, Daejeon 305‑811, Republic of Korea.

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July 2015

Trichosanthes kirilowii ameliorates cisplatin-induced nephrotoxicity in both in vitro and in vivo.

Nat Prod Res 2015 4;29(6):554-7. Epub 2014 Sep 4.

a Basic Herbal Medicine Research Group, Korea Institute of Oriental Medicine , 483 Expo-ro, Yusung-gu, Daejeon 305-811 , South Korea.

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http://www.tandfonline.com/doi/full/10.1080/14786419.2014.95
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April 2015

Traditional Herbal Formula Banhasasim-tang Exerts Anti-Inflammatory Effects in RAW 264.7 Macrophages and HaCaT Keratinocytes.

Evid Based Complement Alternat Med 2015 9;2015:728380. Epub 2015 Mar 9.

Herbal Medicine Formulation Research Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of Korea.

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http://dx.doi.org/10.1155/2015/728380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369961PMC
April 2015

Simultaneous quantification and antiatherosclerosis effect of the traditional Korean medicine, Hwangryunhaedok-tang.

BMC Complement Altern Med 2015 Apr 8;15:108. Epub 2015 Apr 8.

Herbal Medicine Formulation Research Group, Korea Institute of Oriental Medicine, 1672 Yuseong-daero Yuseong-gu, Daejeon, 305-811, South Korea.

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http://dx.doi.org/10.1186/s12906-015-0632-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397668PMC
April 2015

Traditional Herbal Formula Oyaksungi-San Inhibits Adipogenesis in 3T3-L1 Adipocytes.

Evid Based Complement Alternat Med 2015 23;2015:949461. Epub 2015 Feb 23.

Herbal Medicine Formulation Research Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine, 1672 Yuseongdae-ro, Yuseong-gu, Daejeon 305-811, Republic of Korea.

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http://dx.doi.org/10.1155/2015/949461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353446PMC
March 2015

Traditional herbal formula Jakyakgamcho-tang (Paeonia lactiflora and Glycyrrhiza uralensis) impairs inflammatory chemokine production by inhibiting activation of STAT1 and NF-ÎşB in HaCaT cells.

Phytomedicine 2015 Feb 5;22(2):326-32. Epub 2015 Jan 5.

Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2014.12.002DOI Listing
February 2015

Development of validated determination of the eleven marker compounds in Gyejibokryeong-hwan for the quality assessment using HPLC analysis.

Arch Pharm Res 2015 Jan 8;38(1):52-62. Epub 2014 Mar 8.

Herbal Medicine Formulation Research Group, Korea Institute of Oriental Medicine, Daejeon, 305-811, Republic of Korea,

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http://dx.doi.org/10.1007/s12272-014-0363-zDOI Listing
January 2015

Antioxidant and antiadipogenic activities of galkeun-tang, a traditional korean herbal formula.

Evid Based Complement Alternat Med 2014 10;2014:763494. Epub 2014 Dec 10.

Herbal Medicine Formulation Research Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276690PMC
January 2015

Inhibitory activity of Socheongryong‑tang and its constituent components against the production of RANTES, eotaxin, eotaxin‑3 and MMP‑9 from BEAS‑2B cells.

Mol Med Rep 2014 Dec 14;10(6):3035-46. Epub 2014 Oct 14.

Herbal Medicine Formulation Research Group, Korea Institute of Oriental Medicine, Daejeon 305‑811, Republic of Korea.

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December 2014

Subacute Oral Toxicity of Yukmijiwhang-Tang in Crl:CD Sprague-Dawley Rats and Its Cytotoxicity.

Evid Based Complement Alternat Med 2014 5;2014:362573. Epub 2014 Nov 5.

Herbal Medicine Formulation Research Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238173PMC
November 2014

Optimization of the extraction process for the seven bioactive compounds in Yukmijihwang-tang, an herbal formula, using response surface methodology.

Pharmacogn Mag 2014 Aug;10(Suppl 3):S606-13

Herbal Medicine Formulation Research Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189279PMC
August 2014

Genotoxicity evaluation of Guibi-Tang extract using an in vitro bacterial reverse mutation assay, chromosome aberration assay, and in vivo micronucleus test.

BMC Complement Altern Med 2014 Jul 1;14:215. Epub 2014 Jul 1.

Herbal Medicine Formulation Research Group, Korea Institute of Oriental Medicine, 483 Expo-ro, Daejeon 305-811, Yusung-gu, Republic of Korea.

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http://dx.doi.org/10.1186/1472-6882-14-215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094639PMC
July 2014

Simultaneous determination of liquiritin, nodakenin and glycyrrhizinin Guibi-tang, a traditional herbal prescription by HPLC-PDA.

Pak J Pharm Sci 2014 Jul;27(4):819-24

Herbal Medicine Formulation Research Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine, 1672 Yuseongdae-ro, Yuseong-gu, Daejeon, Republic of Korea.

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July 2014

α-Spinasterol from Melandrium firmum attenuates benign prostatic hyperplasia in a rat model.

Mol Med Rep 2014 Jun 28;9(6):2362-6. Epub 2014 Mar 28.

Basic Herbal Medicine Research Group, Korea Institute of Oriental Medicine, Yuseung‑gu, Daejeon 305‑811, Republic of Korea.

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http://dx.doi.org/10.3892/mmr.2014.2081DOI Listing
June 2014

Safety assessment of So-cheong-ryong-tang: subchronic toxicity study in Crl:CD Sprague Dawley rats.

Mol Med Rep 2014 Jun 3;9(6):2273-82. Epub 2014 Apr 3.

Basic Herbal Research Group, Korea Institute of Oriental Medicine, Yuseong‑gu, Daejeon 305‑811, Republic of Korea.

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http://dx.doi.org/10.3892/mmr.2014.2114DOI Listing
June 2014

Non-clinical safety assessment of Hwangryunhaedok-tang: 13-week toxicity in Crl:CD Sprague Dawley rats.

Regul Toxicol Pharmacol 2014 Apr 27;68(3):378-86. Epub 2014 Jan 27.

Basic Herbal Research Group, Korea Institute of Oriental Medicine, 483 Expo-ro, Yusung-gu, Daejeon 305-811, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.yrtph.2014.01.008DOI Listing
April 2014

Effect of sauchinone, a lignan from Saururus chinensis, on bacterial phagocytosis by macrophages.

Eur J Pharmacol 2014 Apr 31;728:176-82. Epub 2014 Jan 31.

Departments of Anesthesiology and Pain Medicine, Chonnam National University Medical School, 5 Hak-dong, Gwangju 501-746, Republic of Korea; Center for Creative Biomedical Scientists at Chonnam National University, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2014.01.039DOI Listing
April 2014

Antiatopic Dermatitis Effect of Artemisia iwayomogi in Dust Mice Extract-Sensitized Nc/Nga Mice.

Evid Based Complement Alternat Med 2014 23;2014:673286. Epub 2014 Feb 23.

Herbal Medicine Formulation Research Group, Korea Institute of Oriental Medicine, 1672 Yuseongdae-ro, Yuseong-gu, Daejeon 305-811, Republic of Korea.

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http://dx.doi.org/10.1155/2014/673286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953474PMC
April 2014

Artemisia capillaris inhibits atopic dermatitis-like skin lesions in Dermatophagoides farinae-sensitized Nc/Nga mice.

BMC Complement Altern Med 2014 Mar 14;14:100. Epub 2014 Mar 14.

Herbal Medicine Formulation Research Group, Korea Institute of Oriental Medicine, 1672 Yuseongdae-ro, Daejeon, Yuseong-gu 305-811, Republic of Korea.

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http://bmccomplementalternmed.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/1472-6882-14-100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995603PMC
March 2014

Simultaneous quantification and inhibitory effect on LDL oxidation of the traditional Korean medicine, Leejung-tang.

BMC Complement Altern Med 2014 Jan 3;14. Epub 2014 Jan 3.

Herbal Medicine Formulation Research Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Yuseongdae-ro 1672, Yuseong-gu, Daejeon, 305-811, Korea.

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http://bmccomplementalternmed.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/1472-6882-14-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913954PMC
January 2014

Sauchinone, a lignan from Saururus chinensis, attenuates neutrophil pro-inflammatory activity and acute lung injury.

Int Immunopharmacol 2013 Oct 5;17(2):471-7. Epub 2013 Aug 5.

Department of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.

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http://dx.doi.org/10.1016/j.intimp.2013.07.011DOI Listing
October 2013

HPLC-PDA analysis and anti-inflammatory effects of Mori Cortex Radicis.

Nat Prod Commun 2013 Oct;8(10):1443-6

Herbal Medicine Formulation Research Group, Korea Institute of Oriental Medicine, 1672 Yuseongda-ro, Yuseong-gu, Daejeon, 305-811, Republic of Korea.

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October 2013