Chandra Sekhar Pedamallu

Chandra Sekhar Pedamallu

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Chandra Sekhar Pedamallu

Chandra Sekhar Pedamallu

Publications by authors named "Chandra Sekhar Pedamallu"

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41Publications

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Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets.

Cancer Biol Ther 2016 12 1;17(12):1274-1281. Epub 2016 Nov 1.

b Department of Medical Oncology & Center for Cancer Genome Discovery , Dana-Farber Cancer Institute, Harvard Medical School , Boston , MA , USA.

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http://dx.doi.org/10.1080/15384047.2016.1250986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199165PMC
December 2016

Validation and calibration of next-generation sequencing to identify Epstein-Barr virus-positive gastric cancer in The Cancer Genome Atlas.

Gastric Cancer 2016 Apr 23;19(2):676-681. Epub 2015 Jun 23.

Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s10120-015-0508-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689675PMC
April 2016

Dynamic epigenetic regulation by menin during pancreatic islet tumor formation.

Mol Cancer Res 2015 Apr 23;13(4):689-98. Epub 2014 Dec 23.

Department of Medical Oncology, Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Cancer program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0457DOI Listing
April 2015

Genetic modifiers of EGFR dependence in non-small cell lung cancer.

Proc Natl Acad Sci U S A 2014 Dec 15;111(52):18661-6. Epub 2014 Dec 15.

Broad Institute of Harvard and MIT, Cambridge, MA 02142; Departments of Pathology and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115; and

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http://dx.doi.org/10.1073/pnas.1412228112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284598PMC
December 2014

A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events.

PLoS One 2014 31;9(1):e87361. Epub 2014 Jan 31.

Cancer Program, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America ; Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087361PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909098PMC
October 2014

EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.

Cancer Discov 2014 Aug 3;4(8):956-71. Epub 2014 Jun 3.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts. Department of Pathology, Boston Children's Hospital, Boston, Massachusetts. Department of Pathology, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125473PMC
August 2014

Landscape of genomic alterations in cervical carcinomas.

Nature 2014 Feb 25;506(7488):371-5. Epub 2013 Dec 25.

1] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA [2] The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA [3] Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA [4].

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http://dx.doi.org/10.1038/nature12881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161954PMC
February 2014

Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients.

J Clin Oncol 2014 Jan 9;32(2):121-8. Epub 2013 Dec 9.

Youngwook Kim, Ji-ae Yoon, Yoomi Lee, Yeong Kyung Yoo, and Keunchil Park, Samsung Medical Center, Samsung Biomedical Research Institute; Jong-Mu Sun, Hong Kwan Kim, Yong Soo Choi, Kwhanmien Kim, Young Mog Shim, Yoon-La Choi, Jhingook Kim, Jin Seok Ahn, Myung-Ju Ahn, and Keunchil Park, Samsung Medical Center, Sungkyunkwan University School of Medicine; Sukki Cho, Seoul National University Bundang Hospital, College of Medicine, Seoul National University, Seoul; In-Jae Oh, Kyu-Sik Kim, Sang-Yun Song, Kook-Ju Na, and Young-Chul Kim, Chonnam National University Hwasun Hospital, Jeonnam, Republic of Korea; Peter S. Hammerman, Jaegil Kim, Chandra Sekhar Pedamallu, Kristian Cibulskis, Michael S. Lawrence, Petar Stojanov, Scott L. Carter, Aaron McKenna, Chip Stewart, Andrey Y. Sivachenko, Gad Getz, and Matthew Meyerson, Broad Institute of Harvard and MIT, Cambridge; Matthew Meyerson, Harvard Medical School; Peter S. Hammerman and Chandra Sekhar Pedamallu, Dana-Farber Cancer Institute; Gad Getz, Massachusetts General Hospital Cancer Center, Boston, MA; and Matthew D. Wilkerson and D. Neil Hayes, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC.

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http://dx.doi.org/10.1200/JCO.2013.50.8556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062710PMC
January 2014

Faster protein splicing with the Nostoc punctiforme DnaE intein using non-native extein residues.

J Biol Chem 2013 Mar 10;288(9):6202-11. Epub 2013 Jan 10.

New England Biolabs, Inc, Ipswich, Massachusetts 01938, USA.

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http://dx.doi.org/10.1074/jbc.M112.433094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585056PMC
March 2013

The Thermococcus kodakaraensis Tko CDC21-1 intein activates its N-terminal splice junction in the absence of a conserved histidine by a compensatory mechanism.

Biochemistry 2012 Mar 13;51(12):2496-505. Epub 2012 Mar 13.

New England BioLabs, Ipswich, Massachusetts 01938, United States.

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http://dx.doi.org/10.1021/bi201840kDOI Listing
March 2012