Chaim O Jacob

Chaim O Jacob

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Chaim O Jacob

Chaim O Jacob

Publications by authors named "Chaim O Jacob"

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Development of murine systemic lupus erythematosus in the absence of BAFF.

Arthritis Rheumatol 2019 Sep 7. Epub 2019 Sep 7.

Division of Rheumatology, Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, 90033.

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http://dx.doi.org/10.1002/art.41097DOI Listing
September 2019

Constitutive reduction in the checkpoint inhibitor, CTLA-4, does not accelerate SLE in NZM 2328 mice.

Lupus Sci Med 2019 19;6(1):e000313. Epub 2019 Feb 19.

Division of Rheumatology, University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1136/lupus-2018-000313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519407PMC
February 2019

TLR7-Mediated Lupus Nephritis Is Independent of Type I IFN Signaling.

J Immunol 2018 07 8;201(2):393-405. Epub 2018 Jun 8.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109;

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http://dx.doi.org/10.4049/jimmunol.1701588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039244PMC
July 2018

A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.

Hum Mol Genet 2018 07;27(13):2392-2404

Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1093/hmg/ddy140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005081PMC
July 2018

Transancestral mapping and genetic load in systemic lupus erythematosus.

Authors:
Carl D Langefeld Hannah C Ainsworth Deborah S Cunninghame Graham Jennifer A Kelly Mary E Comeau Miranda C Marion Timothy D Howard Paula S Ramos Jennifer A Croker David L Morris Johanna K Sandling Jonas Carlsson Almlöf Eduardo M Acevedo-Vásquez Graciela S Alarcón Alejandra M Babini Vicente Baca Anders A Bengtsson Guillermo A Berbotto Marc Bijl Elizabeth E Brown Hermine I Brunner Mario H Cardiel Luis Catoggio Ricard Cervera Jorge M Cucho-Venegas Solbritt Rantapää Dahlqvist Sandra D'Alfonso Berta Martins Da Silva Iñigo de la Rúa Figueroa Andrea Doria Jeffrey C Edberg Emőke Endreffy Jorge A Esquivel-Valerio Paul R Fortin Barry I Freedman Johan Frostegård Mercedes A García Ignacio García de la Torre Gary S Gilkeson Dafna D Gladman Iva Gunnarsson Joel M Guthridge Jennifer L Huggins Judith A James Cees G M Kallenberg Diane L Kamen David R Karp Kenneth M Kaufman Leah C Kottyan László Kovács Helle Laustrup Bernard R Lauwerys Quan-Zhen Li Marco A Maradiaga-Ceceña Javier Martín Joseph M McCune David R McWilliams Joan T Merrill Pedro Miranda José F Moctezuma Swapan K Nath Timothy B Niewold Lorena Orozco Norberto Ortego-Centeno Michelle Petri Christian A Pineau Bernardo A Pons-Estel Janet Pope Prithvi Raj Rosalind Ramsey-Goldman John D Reveille Laurie P Russell José M Sabio Carlos A Aguilar-Salinas Hugo R Scherbarth Raffaella Scorza Michael F Seldin Christopher Sjöwall Elisabet Svenungsson Susan D Thompson Sergio M A Toloza Lennart Truedsson Teresa Tusié-Luna Carlos Vasconcelos Luis M Vilá Daniel J Wallace Michael H Weisman Joan E Wither Tushar Bhangale Jorge R Oksenberg John D Rioux Peter K Gregersen Ann-Christine Syvänen Lars Rönnblom Lindsey A Criswell Chaim O Jacob Kathy L Sivils Betty P Tsao Laura E Schanberg Timothy W Behrens Earl D Silverman Marta E Alarcón-Riquelme Robert P Kimberly John B Harley Edward K Wakeland Robert R Graham Patrick M Gaffney Timothy J Vyse

Nat Commun 2017 07 17;8:16021. Epub 2017 Jul 17.

Divisions of Genetics and Molecular Medicine and Immunology, Infection and Inflammatory Diseases, King's College London, Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1038/ncomms16021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520018PMC
July 2017

Differential Development of Systemic Lupus Erythematosus in NZM 2328 Mice Deficient in Discrete Pairs of BAFF Receptors.

Arthritis Rheumatol 2015 Sep;67(9):2523-35

University of Southern California Keck School of Medicine, Los Angeles.

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http://dx.doi.org/10.1002/art.39210DOI Listing
September 2015

Systemic lupus erythematosus-associated neutrophil cytosolic factor 2 mutation affects the structure of NADPH oxidase complex.

J Biol Chem 2015 May 20;290(20):12595-602. Epub 2015 Mar 20.

From the Lupus Genetic Group, Department of Medicine, University of Southern California, Los Angeles, California 90089,

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http://dx.doi.org/10.1074/jbc.M115.639021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432280PMC
May 2015

Nomenclature of Toso, Fas apoptosis inhibitory molecule 3, and IgM FcR.

J Immunol 2015 May;194(9):4055-7

Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852;

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http://dx.doi.org/10.4049/jimmunol.1500222DOI Listing
May 2015

The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.

Hum Mol Genet 2015 Jan 8;24(2):582-96. Epub 2014 Sep 8.

Division of Rheumatology, Center for Autoimmune Genomics and Etiology and US Department of Veterans Affairs Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.1093/hmg/ddu455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275071PMC
January 2015

IgG1 protects against renal disease in a mouse model of cryoglobulinaemia.

Nature 2015 Jan 2;517(7535):501-4. Epub 2014 Nov 2.

1] Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA [2] Division of Immunology, Allergy and Rheumatology, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA [3] Medical Service, Cincinnati Veterans Affairs Medical Center, Cincinnati, Ohio 45220, USA.

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http://dx.doi.org/10.1038/nature13868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342786PMC
January 2015

Genetics of rheumatoid arthritis: an impressionist perspective.

Rheum Dis Clin North Am 2012 May 22;38(2):243-57. Epub 2012 Jun 22.

Department of Medicine, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue HMR 703, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1016/j.rdc.2012.05.001DOI Listing
May 2012

B Cell and BAFF dependence of IFN-α-exaggerated disease in systemic lupus erythematosus-prone NZM 2328 mice.

J Immunol 2011 Apr 7;186(8):4984-93. Epub 2011 Mar 7.

Division of Rheumatology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.4049/jimmunol.1000466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074466PMC
April 2011

Reflections on Darwinian Evolution - Is there a Jewish Perspective?

Authors:
Chaim O Jacob

Rambam Maimonides Med J 2011 Apr 30;2(2):e0044. Epub 2011 Apr 30.

Professor of Medicine and Molecular Microbiology & Immunology, The Keck School of Medicine, University of Southern California (USC), USA; Director of the Federation of Clinical Immunology Societies (FOCIS) Center for Excellence at USC, Los Angeles, CA, USA.

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http://dx.doi.org/10.5041/RMMJ.10044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678937PMC
April 2011

On anti-tumor necrosis factor-induced systemic lupus erythematosus.

J Rheumatol 2010 Jan;37(1):3-5

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http://dx.doi.org/10.3899/jrheum.091071DOI Listing
January 2010

Function2Gene: a gene selection tool to increase the power of genetic association studies by utilizing public databases and expert knowledge.

BMC Bioinformatics 2008 Jul 17;9:311. Epub 2008 Jul 17.

Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521, USA.

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http://dx.doi.org/10.1186/1471-2105-9-311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500032PMC
July 2008

Paucity of clinical disease despite serological autoimmunity and kidney pathology in lupus-prone New Zealand mixed 2328 mice deficient in BAFF.

J Immunol 2006 Aug;177(4):2671-80

Department of Medicine, Division of Gastrointestinal and Liver Diseases, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, Los Angeles, CA 90033, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896675PMC
http://dx.doi.org/10.4049/jimmunol.177.4.2671DOI Listing
August 2006

The mouse cell surface protein TOSO regulates Fas/Fas ligand-induced apoptosis through its binding to Fas-associated death domain.

J Biol Chem 2005 Mar 4;280(10):9618-26. Epub 2005 Jan 4.

Department of Medicine, University of Southern California School of Medicine, Los Angeles, California 90089, USA.

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http://dx.doi.org/10.1074/jbc.M413609200DOI Listing
March 2005

Pivotal role of Stat4 and Stat6 in the pathogenesis of the lupus-like disease in the New Zealand mixed 2328 mice.

J Immunol 2003 Aug;171(3):1564-71

Department of Medicine, University of Southern California School of Medicine, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.4049/jimmunol.171.3.1564DOI Listing
August 2003

Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis.

J Immunol 2003 May;170(9):4818-25

University of Cincinnati College of Medicine, Department of Internal Medicine, Veterans Affairs Medical Center and Children's Medical Center, Cincinnati, OH 45220, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291553PMC
http://dx.doi.org/10.4049/jimmunol.170.9.4818DOI Listing
May 2003