Publications by authors named "Chaim O Jacob"

73Publications

Inhibition of B cell activation following co-engagement of B cell antigen receptor and Fcγ receptor IIb in non-autoimmune-prone and SLE-prone mice.

J Transl Autoimmun 2021 15;4:100075. Epub 2020 Dec 15.

Division of Rheumatology, Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, 90033, USA.

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December 2020

Essential role and therapeutic targeting of the glomerular endothelial glycocalyx in lupus nephritis.

JCI Insight 2020 Oct 2;5(19). Epub 2020 Oct 2.

Department of Physiology and Neuroscience and Department of Medicine, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

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October 2020

Development of Murine Systemic Lupus Erythematosus in the Absence of BAFF.

Arthritis Rheumatol 2020 02 26;72(2):292-302. Epub 2019 Dec 26.

University of Southern California Keck School of Medicine, Los Angeles.

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February 2020

Constitutive reduction in the checkpoint inhibitor, CTLA-4, does not accelerate SLE in NZM 2328 mice.

Lupus Sci Med 2019 19;6(1):e000313. Epub 2019 Feb 19.

Division of Rheumatology, University of Southern California, Los Angeles, California, USA.

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February 2019

TLR7-Mediated Lupus Nephritis Is Independent of Type I IFN Signaling.

J Immunol 2018 07 8;201(2):393-405. Epub 2018 Jun 8.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109;

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July 2018

Transancestral mapping and genetic load in systemic lupus erythematosus.

Authors:
Carl D Langefeld Hannah C Ainsworth Deborah S Cunninghame Graham Jennifer A Kelly Mary E Comeau Miranda C Marion Timothy D Howard Paula S Ramos Jennifer A Croker David L Morris Johanna K Sandling Jonas Carlsson Almlöf Eduardo M Acevedo-Vásquez Graciela S Alarcón Alejandra M Babini Vicente Baca Anders A Bengtsson Guillermo A Berbotto Marc Bijl Elizabeth E Brown Hermine I Brunner Mario H Cardiel Luis Catoggio Ricard Cervera Jorge M Cucho-Venegas Solbritt Rantapää Dahlqvist Sandra D'Alfonso Berta Martins Da Silva Iñigo de la Rúa Figueroa Andrea Doria Jeffrey C Edberg Emőke Endreffy Jorge A Esquivel-Valerio Paul R Fortin Barry I Freedman Johan Frostegård Mercedes A García Ignacio García de la Torre Gary S Gilkeson Dafna D Gladman Iva Gunnarsson Joel M Guthridge Jennifer L Huggins Judith A James Cees G M Kallenberg Diane L Kamen David R Karp Kenneth M Kaufman Leah C Kottyan László Kovács Helle Laustrup Bernard R Lauwerys Quan-Zhen Li Marco A Maradiaga-Ceceña Javier Martín Joseph M McCune David R McWilliams Joan T Merrill Pedro Miranda José F Moctezuma Swapan K Nath Timothy B Niewold Lorena Orozco Norberto Ortego-Centeno Michelle Petri Christian A Pineau Bernardo A Pons-Estel Janet Pope Prithvi Raj Rosalind Ramsey-Goldman John D Reveille Laurie P Russell José M Sabio Carlos A Aguilar-Salinas Hugo R Scherbarth Raffaella Scorza Michael F Seldin Christopher Sjöwall Elisabet Svenungsson Susan D Thompson Sergio M A Toloza Lennart Truedsson Teresa Tusié-Luna Carlos Vasconcelos Luis M Vilá Daniel J Wallace Michael H Weisman Joan E Wither Tushar Bhangale Jorge R Oksenberg John D Rioux Peter K Gregersen Ann-Christine Syvänen Lars Rönnblom Lindsey A Criswell Chaim O Jacob Kathy L Sivils Betty P Tsao Laura E Schanberg Timothy W Behrens Earl D Silverman Marta E Alarcón-Riquelme Robert P Kimberly John B Harley Edward K Wakeland Robert R Graham Patrick M Gaffney Timothy J Vyse

Nat Commun 2017 07 17;8:16021. Epub 2017 Jul 17.

Divisions of Genetics and Molecular Medicine and Immunology, Infection and Inflammatory Diseases, King's College London, Guy's Hospital, London SE1 9RT, UK.

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July 2017

Systemic lupus erythematosus-associated neutrophil cytosolic factor 2 mutation affects the structure of NADPH oxidase complex.

J Biol Chem 2015 May 20;290(20):12595-602. Epub 2015 Mar 20.

From the Lupus Genetic Group, Department of Medicine, University of Southern California, Los Angeles, California 90089,

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May 2015

IgG1 protects against renal disease in a mouse model of cryoglobulinaemia.

Nature 2015 Jan 2;517(7535):501-4. Epub 2014 Nov 2.

1] Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA [2] Division of Immunology, Allergy and Rheumatology, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA [3] Medical Service, Cincinnati Veterans Affairs Medical Center, Cincinnati, Ohio 45220, USA.

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January 2015

The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.

Hum Mol Genet 2015 Jan 8;24(2):582-96. Epub 2014 Sep 8.

Division of Rheumatology, Center for Autoimmune Genomics and Etiology and US Department of Veterans Affairs Medical Center, Cincinnati, OH, USA.

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January 2015

Genetics of rheumatoid arthritis: an impressionist perspective.

Rheum Dis Clin North Am 2012 May 22;38(2):243-57. Epub 2012 Jun 22.

Department of Medicine, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue HMR 703, Los Angeles, CA 90033, USA.

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May 2012

Reflections on Darwinian Evolution - Is there a Jewish Perspective?

Authors:
Chaim O Jacob

Rambam Maimonides Med J 2011 Apr 30;2(2):e0044. Epub 2011 Apr 30.

Professor of Medicine and Molecular Microbiology & Immunology, The Keck School of Medicine, University of Southern California (USC), USA; Director of the Federation of Clinical Immunology Societies (FOCIS) Center for Excellence at USC, Los Angeles, CA, USA.

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April 2011

B Cell and BAFF dependence of IFN-α-exaggerated disease in systemic lupus erythematosus-prone NZM 2328 mice.

J Immunol 2011 Apr 7;186(8):4984-93. Epub 2011 Mar 7.

Division of Rheumatology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA.

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April 2011

Function2Gene: a gene selection tool to increase the power of genetic association studies by utilizing public databases and expert knowledge.

BMC Bioinformatics 2008 Jul 17;9:311. Epub 2008 Jul 17.

Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521, USA.

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July 2008

Paucity of clinical disease despite serological autoimmunity and kidney pathology in lupus-prone New Zealand mixed 2328 mice deficient in BAFF.

J Immunol 2006 Aug;177(4):2671-80

Department of Medicine, Division of Gastrointestinal and Liver Diseases, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, Los Angeles, CA 90033, USA.

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August 2006

The mouse cell surface protein TOSO regulates Fas/Fas ligand-induced apoptosis through its binding to Fas-associated death domain.

J Biol Chem 2005 Mar 4;280(10):9618-26. Epub 2005 Jan 4.

Department of Medicine, University of Southern California School of Medicine, Los Angeles, California 90089, USA.

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March 2005

Pivotal role of Stat4 and Stat6 in the pathogenesis of the lupus-like disease in the New Zealand mixed 2328 mice.

J Immunol 2003 Aug;171(3):1564-71

Department of Medicine, University of Southern California School of Medicine, Los Angeles, CA 90089, USA.

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August 2003

Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis.

J Immunol 2003 May;170(9):4818-25

University of Cincinnati College of Medicine, Department of Internal Medicine, Veterans Affairs Medical Center and Children's Medical Center, Cincinnati, OH 45220, USA.

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May 2003