Chad V Pecot

Chad V Pecot

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Chad V Pecot

Chad V Pecot

Publications by authors named "Chad V Pecot"

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Phase II study of stereotactic radiosurgery for the treatment of patients with oligoprogression on erlotinib.

Cancer Treat Res Commun 2019 26;19:100126. Epub 2019 Feb 26.

Lineberger Cancer Center at the University of North Carolina, 170 Manning Drive, Room 3115, Campus Box 7305, Chapel Hill, NC 27514, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ctarc.2019.100126DOI Listing
September 2019

Histone deacetylase 11 inhibition promotes breast cancer metastasis from lymph nodes.

Nat Commun 2019 09 13;10(1):4192. Epub 2019 Sep 13.

UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.

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http://dx.doi.org/10.1038/s41467-019-12222-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744422PMC
September 2019

KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism.

Cancer Cell 2018 11;34(5):807-822.e7

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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https://www.researchgate.net/publication/325458004_KRAS_Supp
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https://www.journals.elsevier.com/cancer-cell/recent-article
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https://linkinghub.elsevier.com/retrieve/pii/S15356108183046
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http://dx.doi.org/10.1016/j.ccell.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321749PMC
November 2018

Immunotherapy combinations emerging in non-small-cell lung cancer.

Immunotherapy 2018 06;10(8):627-629

Division of Hematology & Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.2217/imt-2018-0046DOI Listing
June 2018

Targeting Accessories to the Crime: Nanoparticle Nucleic Acid Delivery to the Tumor Microenvironment.

Front Pharmacol 2018 4;9:307. Epub 2018 Apr 4.

UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.

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http://dx.doi.org/10.3389/fphar.2018.00307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893903PMC
April 2018

Incorporating Pericytes into an Endothelial Cell Bead Sprouting Assay.

J Vis Exp 2018 02 16(132). Epub 2018 Feb 16.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill; Department of Medicine, University of North Carolina at Chapel Hill;

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http://dx.doi.org/10.3791/57309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931309PMC
February 2018

Mediating Passive Tumor Accumulation through Particle Size, Tumor Type, and Location.

Nano Lett 2017 05 11;17(5):2879-2886. Epub 2017 Apr 11.

Department of Chemical and Biomolecular Engineering, North Carolina State University , Raleigh, North Carolina 27695, United States.

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http://dx.doi.org/10.1021/acs.nanolett.7b00021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708115PMC
May 2017

Cancer's got nerve: Schwann cells drive perineural invasion.

J Clin Invest 2016 Apr 21;126(4):1242-4. Epub 2016 Mar 21.

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http://dx.doi.org/10.1172/JCI86801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811122PMC
April 2016

Germline Mutation of T790M and Dual/Multiple EGFR Mutations in Patients With Lung Adenocarcinoma.

Clin Lung Cancer 2016 Mar 17;17(2):e5-11. Epub 2015 Nov 17.

Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15257304150026
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http://dx.doi.org/10.1016/j.cllc.2015.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119523PMC
March 2016

Role of Increased n-acetylaspartate Levels in Cancer.

J Natl Cancer Inst 2016 Jan 26;108(6):djv426. Epub 2016 Jan 26.

Departments of Gynecologic Oncology and Reproductive Medicine (BZ, RAP, RR, TM, ASN, HJD, WH, CI, SYW, KMG, SP, LSM, AMN, GAP, AKS), Cancer Systems Imaging (NMZ, CRM, PKB), Biostatistics (MG), Cancer Medicine (CVP), Center for RNA Interference and Non-Coding RNA (CI, LSM, CRA, GLB, AKS), Cancer Biology (YS, MBE, GLB, AKS), Experimental Therapeutics (CRA, GLB), Bioinformatics and Computational Biology (YW, KAB), Melanoma Medical Oncology (MAD), and Pathology (JL), University of Texas M. D. Anderson Cancer Center, Houston, TX; Department of Nanomedicine and Bioengineering, UT Health, Houston, TX (GLB, AKS); Departments of Psychology, Urology, and Obstetrics and Gynecology, the University of Iowa, Iowa City, IA (SKL); Laboratory for Systems Biology of Human Diseases (LY, JB, AA, DN), Department of Chemical and Biomolecular Engineering (LY, JB, AA, DN), and Department of Bioengineering (DN), Rice University, Houston, TX.

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http://dx.doi.org/10.1093/jnci/djv426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849357PMC
January 2016

Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovarian cancers.

J Natl Cancer Inst 2015 Jul 20;107(7). Epub 2015 May 20.

: Departments of Pathology (GL, DY, YS, XL, PJ, DC, LH, WZ), Experimental Therapeutics (CRA, GLB), and Gynecologic Oncology and Reproductive Medicine (RR, LSM, AKS), Division of Cancer Medicine (CVP), Center for RNAi and Non-Coding RNA (RR, CVP, LSM, CRA, GLB, AKS, WZ), the University of Texas MD Anderson Cancer Center, Houston, TX; Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China (GL, YW, FX); Department of Pathology (YS) and Epidemiology (KC), Tianjin Medical University Cancer Institute and Hospital, Tianjin, China; Department of Biochemistry and Molecular Biology, State Key Laboratory of Cancer Biology, the Fourth Military Medical University, Xi'an, China (XL); Institute for Systems Biology, Seattle, WA (IS); Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy (LDC, DM).

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http://academic.oup.com/jnci/article/doi/10.1093/jnci/djv108
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http://dx.doi.org/10.1093/jnci/djv108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554255PMC
July 2015

Differential platelet levels affect response to taxane-based therapy in ovarian cancer.

Clin Cancer Res 2015 Feb 3;21(3):602-10. Epub 2014 Dec 3.

Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315757PMC
February 2015

Therapeutic silencing of KRAS using systemically delivered siRNAs.

Mol Cancer Ther 2014 Dec 3;13(12):2876-85. Epub 2014 Oct 3.

Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1535-7163.MCT-14-0074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416486PMC
December 2014

Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression.

Nat Commun 2014 Oct 29;5:5202. Epub 2014 Oct 29.

1] Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA [2] Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA [3] Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ncomms6202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215647PMC
October 2014

Hematogenous metastasis of ovarian cancer: rethinking mode of spread.

Cancer Cell 2014 Jul;26(1):77-91

Department of Gynecologic Oncology and Reproductive Medicine, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-coding RNA, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100212PMC
July 2014

Notch3 pathway alterations in ovarian cancer.

Cancer Res 2014 Jun 17;74(12):3282-93. Epub 2014 Apr 17.

Authors' Affiliations: Departments of Gynecologic Oncology and Reproductive Medicine, Systems Biology, Pathology, Experimental Therapeutics, Bioinformatics and Computational Biology, Cancer Biology, Thoracic/Head and Neck Medical Oncology, and The Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TexasAuthors' Affiliations: Departments of Gynecologic Oncology and Reproductive Medicine, Systems Biology, Pathology, Experimental Therapeutics, Bioinformatics and Computational Biology, Cancer Biology, Thoracic/Head and Neck Medical Oncology, and The Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TexasAuthors' Affiliations: Departments of Gynecologic Oncology and Reproductive Medicine, Systems Biology, Pathology, Experimental Therapeutics, Bioinformatics and Computational Biology, Cancer Biology, Thoracic/Head and Neck Medical Oncology, and The Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058356PMC
June 2014

Cross-talk between EphA2 and BRaf/CRaf is a key determinant of response to Dasatinib.

Clin Cancer Res 2014 Apr 31;20(7):1846-55. Epub 2014 Jan 31.

Authors' Affiliations: Departments of Gynecologic Oncology and Reproductive Medicine, Hematology and Oncology, Biostatistics, Cancer Biology, and Pathology, and The Center for RNA Interference and Non-Coding RNAs; The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-2141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975695PMC
April 2014

Antagonism of tumoral prolactin receptor promotes autophagy-related cell death.

Cell Rep 2014 Apr 3;7(2):488-500. Epub 2014 Apr 3.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038960PMC
April 2014

Targeting SRC and tubulin in mucinous ovarian carcinoma.

Clin Cancer Res 2013 Dec 7;19(23):6532-43. Epub 2013 Oct 7.

Authors' Affiliations: Departments of Gynecologic Oncology and Reproductive Medicine, Genitourinary Medical Oncology, Bioinformatics and Computational Biology, and Cancer Biology; Division of Cancer Medicine; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas; Kinex Pharmaceuticals LLC, New York State Center of Excellence in Bioinformatics and Life Sciences, Buffalo, New York; Department of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei; Department of Gynecology, Obstetrics and Gynecology, Hospital of Fudan University, Shanghai, P.R. China.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852199PMC
December 2013

Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer.

J Natl Cancer Inst 2013 Oct 23;105(19):1485-95. Epub 2013 Sep 23.

Affiliations of authors: Department of Gynecologic Oncology and Repro ductive Medicine (YK, WH, CI, CVP, HJD, BZ, TL, JH, NBJ, RR, MT, TM, SP, SYW, CL, YW, AKS), Center for RNAi and Non-Coding RNA (CI, AKS), Department of Pathology (JH, JL), and Department of Cancer Biology (AKS), The University of Texas MD Anderson Cancer Center, Houston, TX; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Hospital and Institute of Obstetrics and Gynecology, Shanghai Medical College of Fudan University, Shanghai, China (YK); Department of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China (TL).

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http://dx.doi.org/10.1093/jnci/djt210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787907PMC
October 2013

RNA interference in the clinic: challenges and future directions.

Nat Rev Cancer 2011 Jan 16;11(1):59-67. Epub 2010 Dec 16.

U.T. M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://www.nature.com/articles/nrc2966
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http://dx.doi.org/10.1038/nrc2966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199132PMC
January 2011

A very late stent thrombosis in a patient with diabetes: a call for lifelong dual anti-platelet therapy.

Tenn Med 2009 May;102(5):37-9

Department of Internal Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

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May 2009