Publications by authors named "Celia Delgado"

5 Publications

  • Page 1 of 1

Patients' Perspective of Dystonia Symptoms during the SARS-CoV-2 Pandemic.

Mov Disord 2021 Apr 27. Epub 2021 Apr 27.

Movement Disorders Program, Department of Neurology, Ruber International Hospital, Madrid, Spain.

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http://dx.doi.org/10.1002/mds.28645DOI Listing
April 2021

Jasmonates and Plant Salt Stress: Molecular Players, Physiological Effects, and Improving Tolerance by Using Genome-Associated Tools.

Int J Mol Sci 2021 Mar 17;22(6). Epub 2021 Mar 17.

Institute of Biological Sciences, Campus Talca, Universidad de Talca, Talca 3465548, Chile.

Soil salinity is one of the most limiting stresses for crop productivity and quality worldwide. In this sense, jasmonates (JAs) have emerged as phytohormones that play essential roles in mediating plant response to abiotic stresses, including salt stress. Here, we reviewed the mechanisms underlying the activation and response of the JA-biosynthesis and JA-signaling pathways under saline conditions in and several crops. In this sense, molecular components of JA-signaling such as MYC2 transcription factor and JASMONATE ZIM-DOMAIN (JAZ) repressors are key players for the JA-associated response. Moreover, we review the antagonist and synergistic effects between JA and other hormones such as abscisic acid (ABA). From an applied point of view, several reports have shown that exogenous JA applications increase the antioxidant response in plants to alleviate salt stress. Finally, we discuss the latest advances in genomic techniques for the improvement of crop tolerance to salt stress with a focus on jasmonates.
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http://dx.doi.org/10.3390/ijms22063082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002660PMC
March 2021

Clinical and demographic characteristics of patients with functional movement disorders: a consecutive cohort study from a specialized clinic.

Acta Neurol Belg 2021 Mar 20. Epub 2021 Mar 20.

Functional Movement Disorders Unit, Movement Disorders Program, Department of Neurology, Ruber International Hospital, Madrid, Spain.

There is a growing interest in functional movement disorders (FMD). However, epidemiological data from large cohorts of patients with FMD are scarce and come mainly from General Neurology and Movement Disorders Clinics. Recently, specialized FMD clinics have been developed and epidemiological data from such clinics may provide useful information. We aimed to describe the clinical and sociodemographic features of patients diagnosed with FMD at our specialized FMD clinic. A standardized form was used to extract data from electronic records from the first-100 consecutive patients who were evaluated and diagnosed with FMD at our clinic from 2017 to 2019. Mean age was 40.88 ± (14.02) years, 63% females. Most patients were within working-age range, but only 16% were working at the time of consultation. Mean disease duration was 3.74 ± 5.73 years and was longer among men. The most common FMD were gait disturbance (42%), tremor (22%) and dystonia (15%). A precipitating event (mainly physical) was reported by 74%. The onset was mostly acute (83%) and the clinical course fluctuating (62%). Pain (64%) and fatigue (44%) were common comorbidities. Potential joint-hypermobility was present in 21%, mostly women (90%) and related to the presence of dystonia. FMD affects men and women mostly in working-age. Gait disturbance was the most common diagnosis, possibly because it causes a higher level of disability that may lead to consultation in a specialized clinic. Non-motor symptoms (pain and fatigue) were frequent in this cohort. Further data from specialized units may contribute to both understanding and management of FMD.
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http://dx.doi.org/10.1007/s13760-021-01648-8DOI Listing
March 2021

Impact of the Coronavirus Disease 2019 Pandemic on Functional Movement Disorders: Lessons From a Specialized Clinic.

Mov Disord 2020 10 14;35(10):1723-1724. Epub 2020 Sep 14.

Functional Movement Disorders Unit, Movement Disorders Program, Department of Neurology, Hospital Ruber Internacional, Madrid, Spain.

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http://dx.doi.org/10.1002/mds.28278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461187PMC
October 2020

Field Resistance to and of Transgenic Soybean Expressing the Plant Defensin Gene.

Front Plant Sci 2020 26;11:562. Epub 2020 May 26.

Soybean Biotechnology Laboratory, Plant Biotechnology Department, Center for Genetic Engineering and Biotechnology, Havana, Cuba.

Fungal diseases lead to significant losses in soybean yields and a decline in seed quality; such is the case of the Asian soybean rust and anthracnose caused by and , respectively. Currently, the development of transgenic plants carrying antifungal defensins offers an alternative for plant protection against pathogens. This paper shows the production of transgenic soybean plants expressing the defensin gene using the biolistic delivery system, in an attempt to improve resistance against diseases and reduce the need for chemicals. Transgenic lines were assessed in field conditions under the natural infections of and . The constitutive expression of the gene in transgenic soybean plants was shown to enhance resistance against these important plant pathogens. The quantification of the biomass in infected soybean leaves revealed significant differences between transgenic lines and the non-transgenic control. In certain transgenic lines there was a strong reduction of fungal biomass, revealing a less severe disease. Integration and expression of the transgenes were confirmed by PCR, Southern blot, and qRT-PCR, where the Def1 line showed a higher relative expression of defensin. It was also found that the expression of the defensin gene in plants of the Def1 line did not have a negative effect on the nodulation induced by These results indicate that transgenic soybean plants expressing the defensin gene have a substantially enhanced resistance to economically important diseases, providing a sound environmental approach for decreasing yield losses and lowering the burden of chemicals in agriculture.
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http://dx.doi.org/10.3389/fpls.2020.00562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264373PMC
May 2020