Publications by authors named "Cedric Orelle"

28Publications

Cdr1p highlights the role of the non-hydrolytic ATP-binding site in driving drug translocation in asymmetric ABC pumps.

Biochim Biophys Acta Biomembr 2020 02 14;1862(2):183131. Epub 2019 Nov 14.

Amity Institute of Biotechnology, Amity University Haryana, Gurgaon, India; Amity Institute of Integrative Sciences and Health, Amity University Haryana, Gurgaon, India. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2019.183131DOI Listing
February 2020

ABC systems: structural and functional variations on a common theme.

Res Microbiol 2019 Nov - Dec;170(8):301-303. Epub 2019 Oct 25.

Institut Pasteur, 25 Rue du Dr Roux, 75724 Paris Cedex 15, France. Electronic address:

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http://dx.doi.org/10.1016/j.resmic.2019.10.006DOI Listing
March 2020

Repurposing bioactive aporphine alkaloids as efflux pump inhibitors.

Fitoterapia 2019 Nov 16;139:104371. Epub 2019 Oct 16.

Department of Bioengineering, Marmara University, 34722 Kadikoy, Istanbul, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2019.104371DOI Listing
November 2019

An integrated transport mechanism of the maltose ABC importer.

Res Microbiol 2019 Nov - Dec;170(8):321-337. Epub 2019 Sep 24.

Université de Lyon, CNRS, UMR5086 "Molecular Microbiology and Structural Biochemistry", IBCP, 7 passage du Vercors, 69367 Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.resmic.2019.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906923PMC
January 2020

Multidrug ABC transporters in bacteria.

Res Microbiol 2019 Nov - Dec;170(8):381-391. Epub 2019 Jun 25.

Université de Lyon, CNRS, UMR5086 "Molecular Microbiology and Structural Biochemistry", IBCP, 7 passage du Vercors, 69367 Lyon, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09232508193005
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http://dx.doi.org/10.1016/j.resmic.2019.06.001DOI Listing
January 2020

Flexible-to-rigid transition is central for substrate transport in the ABC transporter BmrA from .

Commun Biol 2019 29;2:149. Epub 2019 Apr 29.

1Molecular Microbiology and Structural Biochemistry, UMR 5086 CNRS/Université de Lyon, Labex Ecofect, 7, passage de Vercors, 69367 Lyon, France.

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http://dx.doi.org/10.1038/s42003-019-0390-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488656PMC
May 2020

Assemblies of lauryl maltose neopentyl glycol (LMNG) and LMNG-solubilized membrane proteins.

Biochim Biophys Acta Biomembr 2019 05 15;1861(5):939-957. Epub 2019 Feb 15.

Univ. Grenoble Alpes, CNRS, CEA, Institute for Structural Biology (IBS), 38000 Grenoble, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2019.02.003DOI Listing
May 2019

A multidrug ABC transporter with a taste for GTP.

Sci Rep 2018 02 2;8(1):2309. Epub 2018 Feb 2.

University of Lyon, CNRS, UMR5086 "Molecular Microbiology and Structural Biochemistry", IBCP, 7 Passage du Vercors, F-69367, Lyon, France.

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http://dx.doi.org/10.1038/s41598-018-20558-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797166PMC
February 2018

Gradient reconstitution of membrane proteins for solid-state NMR studies.

J Biomol NMR 2017 Oct 12;69(2):81-91. Epub 2017 Sep 12.

Molecular Microbiology and Structural Biochemistry, Labex Ecofect, UMR 5086 CNRS-Université de Lyon, IBCP, 7 passage du Vercors, 69367, Lyon, France.

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http://dx.doi.org/10.1007/s10858-017-0135-4DOI Listing
October 2017

Expanding the Kinome World: A New Protein Kinase Family Widely Conserved in Bacteria.

J Mol Biol 2017 10 7;429(20):3056-3074. Epub 2017 Sep 7.

University of Lyon, CNRS, UMR5086 "Molecular Microbiology and Structural Biochemistry," 7 Passage du Vercors, F-69367 Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2017.08.016DOI Listing
October 2017

Context-specific inhibition of translation by ribosomal antibiotics targeting the peptidyl transferase center.

Proc Natl Acad Sci U S A 2016 10 10;113(43):12150-12155. Epub 2016 Oct 10.

Center for Biomolecular Sciences, University of Illinois, Chicago, IL 60607

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http://dx.doi.org/10.1073/pnas.1613055113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086994PMC
October 2016

Protein synthesis by ribosomes with tethered subunits.

Nature 2015 Aug 29;524(7563):119-24. Epub 2015 Jul 29.

Center for Pharmaceutical Biotechnology - m/c 870, University of Illinois at Chicago, 900 South Ashland Avenue, Chicago, Illinois 60607, USA.

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http://dx.doi.org/10.1038/nature14862DOI Listing
August 2015

Tools for characterizing bacterial protein synthesis inhibitors.

Antimicrob Agents Chemother 2013 Dec 16;57(12):5994-6004. Epub 2013 Sep 16.

Center for Pharmaceutical Biotechnology, University of Illinois, Chicago, Illinois, USA.

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http://dx.doi.org/10.1128/AAC.01673-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837844PMC
December 2013

Identifying the targets of aminoacyl-tRNA synthetase inhibitors by primer extension inhibition.

Nucleic Acids Res 2013 Aug 12;41(14):e144. Epub 2013 Jun 12.

Center for Pharmaceutical Biotechnology, University of Illinois, Chicago, IL 60607, USA and Trius Therapeutics, Inc., San Diego, CA 92121, USA.

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https://academic.oup.com/nar/article/41/14/e144/1750316
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http://dx.doi.org/10.1093/nar/gkt526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737564PMC
August 2013

Dynamics of alpha-helical subdomain rotation in the intact maltose ATP-binding cassette transporter.

Proc Natl Acad Sci U S A 2010 Nov 8;107(47):20293-8. Epub 2010 Nov 8.

Chemistry Department, Purdue University, 560 Oval Dr, West Lafayette, IN 47906, USA.

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http://dx.doi.org/10.1073/pnas.1006544107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996640PMC
November 2010

Functional reconstitution of an ABC transporter in nanodiscs for use in electron paramagnetic resonance spectroscopy.

J Am Chem Soc 2010 Jul;132(28):9513-5

Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47906, USA.

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http://dx.doi.org/10.1021/ja104047cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927203PMC
July 2010

Alternating access in maltose transporter mediated by rigid-body rotations.

Mol Cell 2009 Feb;33(4):528-36

Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.

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http://dx.doi.org/10.1016/j.molcel.2009.01.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714826PMC
February 2009

Both maltose-binding protein and ATP are required for nucleotide-binding domain closure in the intact maltose ABC transporter.

Proc Natl Acad Sci U S A 2008 Sep 25;105(35):12837-42. Epub 2008 Aug 25.

Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0803799105
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http://dx.doi.org/10.1073/pnas.0803799105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529024PMC
September 2008

Structure, function, and evolution of bacterial ATP-binding cassette systems.

Microbiol Mol Biol Rev 2008 Jun;72(2):317-64, table of contents

Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA.

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http://dx.doi.org/10.1128/MMBR.00031-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2415747PMC
June 2008

Conformational change induced by ATP binding in the multidrug ATP-binding cassette transporter BmrA.

Biochemistry 2008 Feb 24;47(8):2404-12. Epub 2008 Jan 24.

Institut de Biologie et Chimie des Protéines, UMR 5086 CNRS-Université de Lyon 1 and IFR 128 BioSciences Gerland-Lyon Sud, 7 passage du Vercors, 69367 Lyon, France.

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http://dx.doi.org/10.1021/bi702303sDOI Listing
February 2008

The Q-loop disengages from the first intracellular loop during the catalytic cycle of the multidrug ABC transporter BmrA.

J Biol Chem 2005 Nov 17;280(44):36857-64. Epub 2005 Aug 17.

Institut de Biologie et Chimie des Protéines, Unité Mixte de Recherche 5086 CNRS-UCBL1 and IFR 128, 7 Passage du Vercors, 69367 Lyon Cedex 07, France.

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http://dx.doi.org/10.1074/jbc.M503266200DOI Listing
November 2005

Characterization of YvcC (BmrA), a multidrug ABC transporter constitutively expressed in Bacillus subtilis.

Biochemistry 2004 Jun;43(23):7491-502

Institut de Biologie et Chimie des Protéines, UMR 5086 CNRS-UCBL et IFR 128, 7 passage du Vercors, 69367 Lyon Cedex 07, France.

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http://dx.doi.org/10.1021/bi0362018DOI Listing
June 2004

The conserved glutamate residue adjacent to the Walker-B motif is the catalytic base for ATP hydrolysis in the ATP-binding cassette transporter BmrA.

J Biol Chem 2003 Nov 10;278(47):47002-8. Epub 2003 Sep 10.

Institut de Biologie et Chimie des Protéines, UMR 5086 CNRS-UCBL1 and IFR 128, 7 passage du Vercors, 69367 Lyon Cedex 07, France.

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http://dx.doi.org/10.1074/jbc.M308268200DOI Listing
November 2003

Highly efficient over-production in E. coli of YvcC, a multidrug-like ATP-binding cassette transporter from Bacillus subtilis.

Biochim Biophys Acta 2002 Sep;1565(1):1-5

Institut de Biologie et Chimie des Protéines, UMR 5086 CNRS/Université Claude Bernard Lyon I, 7 passage du Vercors, 69367, Lyon, France.

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http://dx.doi.org/10.1016/s0005-2736(02)00515-1DOI Listing
September 2002

Three-dimensional structure by cryo-electron microscopy of YvcC, an homodimeric ATP-binding cassette transporter from Bacillus subtilis.

J Mol Biol 2002 Feb;315(5):1075-85

Institut Curie Section Recherche, UMR-CNRS 168 et LRC-CEA 8, 11 Rue Pierre et Marie Curie, Paris Cedex 05, 75231, France.

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http://linkinghub.elsevier.com/retrieve/pii/S002228360195309
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http://dx.doi.org/10.1006/jmbi.2001.5309DOI Listing
February 2002