Cato T Laurencin

Cato T Laurencin

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Insulin immobilized PCL-cellulose acetate micro-nanostructured fibrous scaffolds for tendon tissue engineering.

Polym Adv Technol 2019 May 4;30(5):1205-1215. Epub 2019 Feb 4.

Department of Materials Science and Engineering, University of Connecticut, Storrs, Connecticut.

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http://dx.doi.org/10.1002/pat.4553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448803PMC
May 2019

Phosphate graphene as an intrinsically osteoinductive scaffold for stem cell-driven bone regeneration.

Proc Natl Acad Sci U S A 2019 03 22;116(11):4855-4860. Epub 2019 Feb 22.

Department of Chemistry, Carnegie Mellon University, Pittsburgh, PA 15213;

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http://dx.doi.org/10.1073/pnas.1815434116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421425PMC
March 2019

Nanofiber/Microsphere Hybrid Matrices for Bone Regenerative Engineering: A Preliminary Report.

Regen Eng Transl Med 2018 Sep 14;4(3):133-141. Epub 2018 Jun 14.

The Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences, Institute for Regenerative Engineering, University of Connecticut Health Center, School of Medicine, Farmington, Connecticut 06030.

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http://link.springer.com/10.1007/s40883-018-0055-1
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http://dx.doi.org/10.1007/s40883-018-0055-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345177PMC
September 2018

Injectable nanocomposite analgesic delivery system for musculoskeletal pain management.

Acta Biomater 2018 07 25;74:280-290. Epub 2018 May 25.

Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, USA; Institute for Regenerative Engineering, The Raymond Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences, University of Connecticut Health Center, Farmington, USA; Department of Biomedical Engineering, University of Connecticut, Storrs, USA; Department of Material Science and Engineering, Institute of Material Science, University of Connecticut, Storrs, USA. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2018.05.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020057PMC
July 2018

Growth factor delivery strategies for rotator cuff repair and regeneration.

Int J Pharm 2018 Jun 6;544(2):358-371. Epub 2018 Jan 6.

Institute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT 06030, USA; Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences, University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Biomedical Engineering, University of Connecticut, Storrs, CT, 06269, USA; Department of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT, 06269, USA; Department of Materials Science and Engineering, University of Connecticut, Storrs, CT, 06269, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2018.01.006DOI Listing
June 2018

HIV/AIDS and the African-American Community 2018: a Decade Call to Action.

J Racial Ethn Health Disparities 2018 Jun 4;5(3):449-458. Epub 2018 Jun 4.

Connecticut Institute for Clinical and Translational Science at the University of Connecticut (CICATS) - CEO, Farmington, CT, USA.

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http://link.springer.com/10.1007/s40615-018-0491-0
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http://dx.doi.org/10.1007/s40615-018-0491-0DOI Listing
June 2018

Biodegradable Piezoelectric Force Sensor.

Proc Natl Acad Sci U S A 2018 01 16;115(5):909-914. Epub 2018 Jan 16.

Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269;

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http://dx.doi.org/10.1073/pnas.1710874115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798324PMC
January 2018

Engineered stem cell niche matrices for rotator cuff tendon regenerative engineering.

PLoS One 2017 3;12(4):e0174789. Epub 2017 Apr 3.

Institute for Regenerative Engineering, University of Connecticut Health Center, Farmington, Connecticut, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0174789PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378368PMC
August 2017

Harnessing cAMP signaling in musculoskeletal regenerative engineering.

Drug Discov Today 2017 07 27;22(7):1027-1044. Epub 2017 Mar 27.

Institute for Regenerative Engineering, University of Connecticut Health Center, School of Medicine, Farmington, CT 06030, USA; The Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences, University of Connecticut Health Center, School of Medicine, Farmington, CT 06030, USA; Department of Orthopedic Surgery, University of Connecticut Health Center, Farmington, CT 06030, USA; Connecticut Institute for Clinical and Translational Science, University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Medicine, Division of Endocrinology, University of Connecticut Health Center, School of Medicine, Farmington, CT 06030, USA; UConn Stem Cell Institute, University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Biomedical Engineering, University of Connecticut, School of Engineering, Storrs, CT 06268, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2017.03.008DOI Listing
July 2017

An American Crisis: the Lack of Black Men in Medicine.

J Racial Ethn Health Disparities 2017 06 22;4(3):317-321. Epub 2017 May 22.

School of Medicine, University of Connecticut Health Center, Farmington, CT, USA.

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http://link.springer.com/10.1007/s40615-017-0380-y
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http://dx.doi.org/10.1007/s40615-017-0380-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909952PMC
June 2017

Microsphere-Based Scaffolds in Regenerative Engineering.

Annu Rev Biomed Eng 2017 06;19:135-161

Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma 73019; email:

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http://dx.doi.org/10.1146/annurev-bioeng-071516-044712DOI Listing
June 2017

Biodegradable Polyphosphazene-Based Blends for Regenerative Engineering.

Regen Eng Transl Med 2017 Mar 30;3(1):15-31. Epub 2017 Jan 30.

Department of Materials Science and Engineering, University of Connecticut, Storrs, CT 06269, USA.

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http://dx.doi.org/10.1007/s40883-016-0022-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459410PMC
March 2017

Poly (lactic acid)-based biomaterials for orthopaedic regenerative engineering.

Adv Drug Deliv Rev 2016 12 25;107:247-276. Epub 2016 Apr 25.

Institute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT 06030, USA; Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences, University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT 06030, USA; School of Medicine, University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Reconstructive Sciences, University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT 06269, USA; Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA; Department of Materials Science and Engineering, University of Connecticut, Storrs, CT 06269, USA. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2016.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482531PMC
December 2016

The past, present and future of ligament regenerative engineering.

Regen Med 2016 12 23;11(8):871-881. Epub 2016 Nov 23.

Institute for Regenerative Engineering, University of Connecticut Health, Farmington, CT 06030, USA.

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http://dx.doi.org/10.2217/rme-2016-0125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967361PMC
December 2016

One-day treatment of small molecule 8-bromo-cyclic AMP analogue induces cell-based VEGF production for in vitro angiogenesis and osteoblastic differentiation.

J Tissue Eng Regen Med 2016 10 6;10(10):867-875. Epub 2013 Nov 6.

Institute for Regenerative Engineering, University of Connecticut Health Center, School of Medicine, Farmington, CT, USA.

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http://doi.wiley.com/10.1002/term.1839
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http://dx.doi.org/10.1002/term.1839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497951PMC
October 2016

Short-term administration of small molecule phenamil induced a protracted osteogenic effect on osteoblast-like MC3T3-E1 cells.

J Tissue Eng Regen Med 2016 06 30;10(6):518-26. Epub 2013 Jul 30.

Department of Orthopedic Surgery, University of Connecticut Health Center, School of Medicine, Farmington, CT, USA.

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http://dx.doi.org/10.1002/term.1786DOI Listing
June 2016

The Quest toward limb regeneration: a regenerative engineering approach.

Regen Biomater 2016 Jun 5;3(2):123-5. Epub 2016 Mar 5.

Department of Orthopaedic Surgery, Institute for Regenerative Engineering, Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences, University of Connecticut Health, Farmington, CT 06030, USA,; Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA,; Department of Materials Science and Engineering, University of Connecticut, Storrs, CT 06269, USA.

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http://dx.doi.org/10.1093/rb/rbw002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817321PMC
June 2016

Nanofiber technology: its transformative role in nanomedicine.

Nanomedicine (Lond) 2016 06 1;11(12):1499-501. Epub 2016 Jun 1.

Department of Orthopaedic Surgery, The University of Connecticut Health Center, Farmington, CT 06030, USA.

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http://dx.doi.org/10.2217/nnm.16.44DOI Listing
June 2016

Simple signaling molecules for inductive bone regenerative engineering.

PLoS One 2014 14;9(7):e101627. Epub 2014 Jul 14.

Institute for Regenerative Engineering, University of Connecticut Health Center, Farmington, Connecticut, United States of America; Raymond and Beverly Sackler Center for Biological, Physical and Engineering Sciences, University of Connecticut Health Center, Farmington, Connecticut, United States of America; Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, Connecticut, United States of America; Department of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, Connecticut, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101627PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096515PMC
April 2016

Animal models of osteoarthritis: classification, update, and measurement of outcomes.

J Orthop Surg Res 2016 Feb 2;11:19. Epub 2016 Feb 2.

Institute for Regenerative Engineering, University of Connecticut Health, Farmington, CT, USA.

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http://dx.doi.org/10.1186/s13018-016-0346-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738796PMC
February 2016

The Fight for the Elimination of Racial and Ethnic Health Disparities: Acknowledging the Work and Celebrating the Life of Mr. Louis Stokes.

J Racial Ethn Health Disparities 2015 Dec 28;2(4):423-4. Epub 2015 Sep 28.

The W. Montague Cobb/NMA Health Institute, Washington, DC, USA.

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http://dx.doi.org/10.1007/s40615-015-0168-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750495PMC
December 2015

Regenerative Engineering of Cartilage Using Adipose-Derived Stem Cells.

Regen Eng Transl Med 2015 Dec 30;1(1):42-49. Epub 2015 Nov 30.

Institute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT 06030, USA; Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences, University of Connecticut Health Center, Farmington, CT 06030, USA; School of Medicine, University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Reconstructive Sciences, University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT 06269, USA; Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA; Department of Materials Science and Engineering, University of Connecticut, Storrs, CT 06269, USA.

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http://dx.doi.org/10.1007/s40883-015-0005-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795960PMC
December 2015

Biomaterials for Bone Regenerative Engineering.

Adv Healthc Mater 2015 Jun 7;4(9):1268-85. Epub 2015 Apr 7.

Institute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT, 06030, USA.

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http://dx.doi.org/10.1002/adhm.201400760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507442PMC
June 2015

REGENERATIVE ENGINEERING: APPROACHES TO LIMB REGENERATION AND OTHER GRAND CHALLENGES.

Regen Eng Transl Med 2015 Apr 4;1(1):1-3. Epub 2015 Dec 4.

Department of Orthopaedic Surgery; Institute for Regenerative Engineering; Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences; University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Biomedical Engineering; Department of Materials Science and Engineering, Storrs, CT 06269, USA.

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http://dx.doi.org/10.1007/s40883-015-0006-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789288PMC
April 2015

Regenerative Engineering and Bionic Limbs.

Rare Metals 2015 Mar;34(3):143-155

Institute for Regenerative Engineering, University of Connecticut Health Center, Farmington, Connecticut 06030, USA ; Raymond and Beverly Sackler Center for Biological, Physical and Engineering Sciences, University of Connecticut Health Center, Connecticut 06030, USA ; Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, Connecticut 06030, USA ; Connecticut Institute for Clinical and Translational Science, Farmington, Connecticut 06030, USA ; Department of Chemical, Materials and Biomolecular Engineering, University of Connecticut, Storrs, Connecticut 06269, USA.

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http://dx.doi.org/10.1007/s12598-015-0446-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429301PMC
March 2015

Pain management via local anesthetics and responsive hydrogels.

Ther Deliv 2015 Feb;6(2):165-76

Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA.

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http://dx.doi.org/10.4155/tde.14.95DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500150PMC
February 2015

Nanofiber-microsphere (nano-micro) matrices for bone regenerative engineering: a convergence approach toward matrix design.

Regen Biomater 2014 Nov 20;1(1):3-9. Epub 2014 Oct 20.

Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences, Institute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT 06030, USA, Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT 06030, USA, Department of Materials Science and Engineering, University of Connecticut, Storrs, CT 06269, USA, Department of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT 06269, USA.

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http://dx.doi.org/10.1093/rb/rbu002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669008PMC
November 2014

Evaluating the feasibility of utilizing the small molecule phenamil as a novel biofactor for bone regenerative engineering.

J Tissue Eng Regen Med 2014 Sep 19;8(9):728-36. Epub 2012 Jul 19.

Institute for Regenerative Engineering, University of Connecticut Health Center, School of Medicine, Farmington, CT, USA; Department of Medicine, Division of Endocrinology, University of Connecticut Health Center, School of Medicine, Farmington, CT, USA.

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http://doi.wiley.com/10.1002/term.1573
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http://dx.doi.org/10.1002/term.1573DOI Listing
September 2014

Facile fabrication of polyanhydride/anesthetic nanoparticles with tunable release kinetics.

Adv Healthc Mater 2014 Jun 27;3(6):843-7. Epub 2013 Dec 27.

Institute for Regenerative Engineering, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030, USA; Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030, USA; Department of Orthopaedic Surgery, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030, USA.

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http://dx.doi.org/10.1002/adhm.201300521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053479PMC
June 2014

Delivery of small molecules for bone regenerative engineering: preclinical studies and potential clinical applications.

Drug Discov Today 2014 Jun 6;19(6):794-800. Epub 2014 Feb 6.

Institute for Regenerative Engineering, University of Connecticut Health Center, School of Medicine, Farmington, CT 06030, USA; The Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences, University of Connecticut Health Center, School of Medicine, Farmington, CT 06030, USA; Department of Biomedical Engineering, University of Connecticut, School of Engineering, Storrs, CT 06268, USA; Department of Medicine, Division of Endocrinology, University of Connecticut Health Center, School of Medicine, Farmington, CT 06030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2014.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048776PMC
June 2014

Functionalized carbon nanotube reinforced scaffolds for bone regenerative engineering: fabrication, in vitro and in vivo evaluation.

Biomed Mater 2014 Jun 31;9(3):035001. Epub 2014 Mar 31.

Institute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT 06032, USA. Materials Science & Engineering, University of Connecticut, Storrs, CT 06269, USA. Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences Center.

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http://dx.doi.org/10.1088/1748-6041/9/3/035001DOI Listing
June 2014

Micro- and nanofabrication of chitosan structures for regenerative engineering.

Acta Biomater 2014 Apr 12;10(4):1632-45. Epub 2013 Jul 12.

Institute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT 06030, USA; Raymond and Beverly Sackler Center for Biological, Physical and Engineering Sciences, University of Connecticut Health Center, CT 06030, USA; Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Chemical, Materials and Biomolecular Engineering, University of Connecticut, Storrs, CT 06269, USA. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2013.07.003DOI Listing
April 2014

Small-molecule based musculoskeletal regenerative engineering.

Trends Biotechnol 2014 Feb 6;32(2):74-81. Epub 2014 Jan 6.

Institute for Regenerative Engineering, University of Connecticut Health Center, School of Medicine, Farmington, CT 06030, USA; The Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences, University of Connecticut Health Center, School of Medicine, Farmington, CT 06030, USA; Department of Biomedical Engineering, University of Connecticut, School of Engineering, Storrs, CT 06268, USA; Department of Orthopaedic Surgery, University of Connecticut Health Center, School of Medicine, Farmington, CT 06030, USA; Department of Chemical, Materials and Biomolecular Engineering, University of Connecticut, School of Engineering, Storrs, CT 06268, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tibtech.2013.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992320PMC
February 2014

Bone morphogenetic proteins for bone regeneration and their alternatives.

Curr Pharm Des 2013 ;19(19):3353

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November 2013

Nano-ceramic composite scaffolds for bioreactor-based bone engineering.

Clin Orthop Relat Res 2013 Aug;471(8):2422-33

Institute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT 06003, USA.

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http://dx.doi.org/10.1007/s11999-013-2859-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705070PMC
August 2013

Bone tissue engineering: recent advances and challenges.

Crit Rev Biomed Eng 2012 ;40(5):363-408

Department of Orthopedic Surgery, University of Connecticut Health Center, Farmington, CT, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766369PMC
May 2013

Cellulose and collagen derived micro-nano structured scaffolds for bone tissue engineering.

J Biomed Nanotechnol 2013 Apr;9(4):719-31

Institute for Regenerative Engineering, University of Connecticut Health Center Connecticut 06030, USA.

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April 2013

A chitosan thermogel for delivery of ropivacaine in regional musculoskeletal anesthesia.

Biomaterials 2013 Mar 12;34(10):2539-46. Epub 2013 Jan 12.

Office of Animal Welfare, University of Virginia, Virginia, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01429612120141
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http://dx.doi.org/10.1016/j.biomaterials.2012.12.035DOI Listing
March 2013

VEGF-incorporated biomimetic poly(lactide-co-glycolide) sintered microsphere scaffolds for bone tissue engineering.

J Biomed Mater Res B Appl Biomater 2012 Nov 22;100(8):2187-96. Epub 2012 Aug 22.

Department of Chemical Engineering, University of South Carolina, South Carolina 29208, USA.

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http://doi.wiley.com/10.1002/jbm.b.32787
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http://dx.doi.org/10.1002/jbm.b.32787DOI Listing
November 2012

Regenerative engineering.

Sci Transl Med 2012 Nov;4(160):160ed9

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http://stm.sciencemag.org/cgi/doi/10.1126/scitranslmed.30044
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http://dx.doi.org/10.1126/scitranslmed.3004467DOI Listing
November 2012

Differential analysis of peripheral blood- and bone marrow-derived endothelial progenitor cells for enhanced vascularization in bone tissue engineering.

J Orthop Res 2012 Sep 29;30(9):1507-15. Epub 2012 Feb 29.

Institute for Regenerative Engineering, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, Connecticut 06032, USA.

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http://dx.doi.org/10.1002/jor.22097DOI Listing
September 2012

Studies of bone morphogenetic protein-based surgical repair.

Adv Drug Deliv Rev 2012 Sep 2;64(12):1277-91. Epub 2012 Apr 2.

Department of Orthopaedic Surgery, University of Connecticut Health Center, School of Medicine, Farmington, CT 06030, USA.

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http://dx.doi.org/10.1016/j.addr.2012.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401330PMC
September 2012

Injectable thermogelling chitosan for the local delivery of bone morphogenetic protein.

J Mater Sci Mater Med 2012 Sep 3;23(9):2141-9. Epub 2012 Jun 3.

School of Medicine, University of Connecticut Health Center, Farmington, CT 06030, USA.

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http://dx.doi.org/10.1007/s10856-012-4677-4DOI Listing
September 2012

Optimally porous and biomechanically compatible scaffolds for large-area bone regeneration.

Tissue Eng Part A 2012 Jul 16;18(13-14):1376-88. Epub 2012 Apr 16.

Institute for Regenerative Engineering, University of Connecticut Health Center, 263 Farmington Ave., Farmington, CT 06030, USA.

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http://dx.doi.org/10.1089/ten.TEA.2011.0076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802344PMC
July 2012

The role of small molecules in musculoskeletal regeneration.

Regen Med 2012 Jul;7(4):535-49

Institute for Regenerative Engineering, University of Connecticut Health Center, School of Medicine, Farmington, CT 06030, USA.

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http://dx.doi.org/10.2217/rme.12.33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698169PMC
July 2012

Nanostructured polymeric scaffolds for orthopaedic regenerative engineering.

IEEE Trans Nanobioscience 2012 Mar 23;11(1):3-14. Epub 2012 Jan 23.

Institute for Regenerative Engineering and Departmentof Orthopaedic Surgery at the University of Connecticut Health Center, Farmington, CT 06030, USA.

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http://dx.doi.org/10.1109/TNB.2011.2179554DOI Listing
March 2012

The small molecule PKA-specific cyclic AMP analogue as an inducer of osteoblast-like cells differentiation and mineralization.

J Tissue Eng Regen Med 2012 Jan 10;6(1):40-8. Epub 2011 Feb 10.

Department of Orthopaedic Surgery, Institute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT, USA.

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http://dx.doi.org/10.1002/term.395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133873PMC
January 2012

Electrospun nanofibrous scaffolds for engineering soft connective tissues.

Methods Mol Biol 2011 ;726:243-58

Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT, USA.

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http://dx.doi.org/10.1007/978-1-61779-052-2_16DOI Listing
June 2011

Biomedical Applications of Biodegradable Polymers.

J Polym Sci B Polym Phys 2011 Jun;49(12):832-864

Department of Orthopaedic Surgery, New England Musculoskeletal Institute, University of Connecticut Health Center, Farmington, Connecticut 06030.

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http://dx.doi.org/10.1002/polb.22259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136871PMC
June 2011

Improved bio-implant using ultrafast laser induced self-assembled nanotexture in titanium.

J Biomed Mater Res B Appl Biomater 2011 May 10;97(2):299-305. Epub 2011 Mar 10.

Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1002/jbm.b.31815DOI Listing
May 2011

Activation of cyclic amp/protein kinase: a signaling pathway enhances osteoblast cell adhesion on biomaterials for regenerative engineering.

J Orthop Res 2011 Apr 18;29(4):602-8. Epub 2010 Oct 18.

Department of Orthopaedic Surgery, New England Musculoskeletal Institute, University of Connecticut Health Center, Farmington, Connecticut 06030, USA.

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http://dx.doi.org/10.1002/jor.21276DOI Listing
April 2011

Development and characterization of biodegradable nanocomposite injectables for orthopaedic applications based on polyphosphazenes.

J Biomater Sci Polym Ed 2011 21;22(4-6):733-52. Epub 2010 Jun 21.

Center for Nanotechnology & Advanced Biomaterials, SASTRA University, Thanjavur, India.

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http://dx.doi.org/10.1163/092050610X491670DOI Listing
March 2011

Evaluation of a hydrogel-fiber composite for ACL tissue engineering.

J Biomech 2011 Feb 15;44(4):694-9. Epub 2010 Dec 15.

Virginia Tech-Wake Forest School of Biomedical Engineering and Sciences, Blacksburg, VA 24061, USA.

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http://dx.doi.org/10.1016/j.jbiomech.2010.10.043DOI Listing
February 2011

2010 Panel on the biomaterials grand challenges.

J Biomed Mater Res A 2011 Feb 29;96(2):275-87. Epub 2010 Nov 29.

Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA.

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http://dx.doi.org/10.1002/jbm.a.32969DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076103PMC
February 2011

Composite scaffolds: bridging nanofiber and microsphere architectures to improve bioactivity of mechanically competent constructs.

J Biomed Mater Res A 2010 Dec 28;95(4):1150-8. Epub 2010 Sep 28.

Department of Bioengineering, Pennsylvania State University, University Park, Pennsylvania 16802, USA.

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http://dx.doi.org/10.1002/jbm.a.32934DOI Listing
December 2010

The indications and use of bone morphogenetic proteins in foot, ankle, and tibia surgery.

Foot Ankle Clin 2010 Dec;15(4):543-51

Division of Orthopaedic Surgery, Southern Illinois University School of Medicine, PO Box 19679, Springfield, IL 62794-9620, USA.

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http://dx.doi.org/10.1016/j.fcl.2010.08.001DOI Listing
December 2010

Miscibility of choline-substituted polyphosphazenes with PLGA and osteoblast activity on resulting blends.

Biomaterials 2010 Nov 25;31(33):8507-15. Epub 2010 Aug 25.

Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2010.07.094DOI Listing
November 2010

Chitosan-poly(lactide-co-glycolide) microsphere-based scaffolds for bone tissue engineering: in vitro degradation and in vivo bone regeneration studies.

Acta Biomater 2010 Sep 20;6(9):3457-70. Epub 2010 Mar 20.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904, USA.

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http://dx.doi.org/10.1016/j.actbio.2010.03.023DOI Listing
September 2010

In Situ Porous Structures: A Unique Polymer Erosion Mechanism in Biodegradable Dipeptide-based Polyphosphazene and Polyester Blends Producing Matrices for Regenerative Engineering.

Adv Funct Mater 2010 Sep;20(17):2743-2957

Department of Orthopaedic Surgery, University of Connecticut, Farmington, CT, 06030 (USA); Department of Chemical Engineering, University of Virginia, Charlottesville, VA, 22904 (USA).

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http://dx.doi.org/10.1002/adfm.201090073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141818PMC
September 2010

Tissue-engineered matrices as functional delivery systems: adsorption and release of bioactive proteins from degradable composite scaffolds.

J Biomed Mater Res A 2010 Aug;94(2):568-75

Department of Chemical Engineering, The University of Virginia, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1002/jbm.a.32722DOI Listing
August 2010

Functionalization of chitosan/poly(lactic acid-glycolic acid) sintered microsphere scaffolds via surface heparinization for bone tissue engineering.

J Biomed Mater Res A 2010 Jun;93(3):1193-208

Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia 22904, USA.

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http://doi.wiley.com/10.1002/jbm.a.32615
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June 2010

Spiral-structured, nanofibrous, 3D scaffolds for bone tissue engineering.

J Biomed Mater Res A 2010 May;93(2):753-62

Department of Chemical, Biomedical and Materials Engineering, Stevens Institute of Technology, Hoboken, New Jersey 07030, USA.

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http://dx.doi.org/10.1002/jbm.a.32591DOI Listing
May 2010

Nanotechnology and orthopedics: a personal perspective.

Wiley Interdiscip Rev Nanomed Nanobiotechnol 2009 Jan-Feb;1(1):6-10

Department of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06030, USA.

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http://dx.doi.org/10.1002/wnan.25DOI Listing
March 2010

Multipotential differentiation of human anulus fibrosus cells: an in vitro study.

J Bone Joint Surg Am 2010 Mar;92(3):675-85

Department of Orthopaedic Surgery, Nanchong Central Hospital, North Sichuan Medical College, Nanchong 637000, PR China.

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https://insights.ovid.com/crossref?an=00004623-201003000-000
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http://dx.doi.org/10.2106/JBJS.H.01672DOI Listing
March 2010

Biomimetic, bioactive etheric polyphosphazene-poly(lactide-co-glycolide) blends for bone tissue engineering.

J Biomed Mater Res A 2010 Jan;92(1):114-25

Department of Orthopaedic Surgery, University of Connecticut, Farmington, Connecticut 06030, USA.

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http://dx.doi.org/10.1002/jbm.a.32334DOI Listing
January 2010

Fabrication, characterization, and in vitro evaluation of poly(lactic acid glycolic acid)/nano-hydroxyapatite composite microsphere-based scaffolds for bone tissue engineering in rotating bioreactors.

J Biomed Mater Res A 2009 Dec;91(3):679-91

Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1002/jbm.a.32302DOI Listing
December 2009

Curcumin-loaded poly(epsilon-caprolactone) nanofibres: diabetic wound dressing with anti-oxidant and anti-inflammatory properties.

Clin Exp Pharmacol Physiol 2009 Dec 19;36(12):1149-56. Epub 2009 May 19.

Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1111/j.1440-1681.2009.05216.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796710PMC
December 2009

Tissue engineering of the anterior cruciate ligament: the viscoelastic behavior and cell viability of a novel braid-twist scaffold.

J Biomater Sci Polym Ed 2009 ;20(12):1709-28

School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA 24061, USA.

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https://www.tandfonline.com/doi/full/10.1163/156856208X38628
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November 2009

Biodegradable polyphosphazene-nanohydroxyapatite composite nanofibers: scaffolds for bone tissue engineering.

J Biomed Nanotechnol 2009 Feb;5(1):69-75

Department of Chemistry, University of Virginia, Virginia 22903, USA.

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February 2009

Tissue engineering of bone: a primer for the practicing hand surgeon.

J Hand Surg Am 2009 Jan;34(1):164-6

Department of Orthopaedic Surgery, Materials and Biomolecular Engineering, University of Connecticut, Farmington, CT 06030, USA.

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http://dx.doi.org/10.1016/j.jhsa.2008.09.002DOI Listing
January 2009

Electrospun poly(lactic acid-co-glycolic acid) scaffolds for skin tissue engineering.

Biomaterials 2008 Oct 21;29(30):4100-7. Epub 2008 Jul 21.

Department of Orthopedic Surgery, University of Virginia, Charlottesville, VA 22903, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2008.06.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605109PMC
October 2008

Solvent/non-solvent sintering: a novel route to create porous microsphere scaffolds for tissue regeneration.

J Biomed Mater Res B Appl Biomater 2008 Aug;86(2):396-406

Department of Biomedical Engineering, University of Virginia, Virginia, USA.

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http://dx.doi.org/10.1002/jbm.b.31033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755242PMC
August 2008

Induction of angiogenesis in tissue-engineered scaffolds designed for bone repair: a combined gene therapy-cell transplantation approach.

Proc Natl Acad Sci U S A 2008 Aug 4;105(32):11099-104. Epub 2008 Aug 4.

Departments of Orthopaedic Surgery and Chemical Engineering, University of Virginia, Charlottesville, VA 22908, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0800069105
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516212PMC
August 2008

Polyphosphazene/nano-hydroxyapatite composite microsphere scaffolds for bone tissue engineering.

Biomacromolecules 2008 Jul 3;9(7):1818-25. Epub 2008 Jun 3.

Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1021/bm800031tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746952PMC
July 2008

The FDA and safety--beyond the heparin crisis.

Nat Biotechnol 2008 Jun;26(6):621-3

Orthopaedic Surgery, University of Connecticut, Connecticut, USA.

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http://www.nature.com/articles/nbt0608-621
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June 2008

Adenovirus-mediated expression of growth and differentiation factor-5 promotes chondrogenesis of adipose stem cells.

Growth Factors 2008 Jun;26(3):132-42

Department of Orthopaedic Surgery, The Second Clinical Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, People's Republic of China.

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http://dx.doi.org/10.1080/08977190802105917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034080PMC
June 2008

Apatite nano-crystalline surface modification of poly(lactide-co-glycolide) sintered microsphere scaffolds for bone tissue engineering: implications for protein adsorption.

J Biomater Sci Polym Ed 2007 ;18(9):1141-52

Department of Orthopaedic Surgery, University of Virginia, 400 Ray C. Hunt Drive, Suite 330, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1163/156856207781554073DOI Listing
May 2008

Mouse growth and differentiation factor-5 protein and DNA therapy potentiates intervertebral disc cell aggregation and chondrogenic gene expression.

Spine J 2008 Mar-Apr;8(2):287-95. Epub 2007 Jul 6.

Department of Orthopaedic Surgery, University of Virginia, Hospital Drive, Cobb Hall, P.O. Box 800374, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1016/j.spinee.2007.05.012DOI Listing
May 2008

Biologically active chitosan systems for tissue engineering and regenerative medicine.

Curr Top Med Chem 2008 ;8(4):354-64

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904, USA.

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May 2008

Biphasic scaffold for annulus fibrosus tissue regeneration.

Biomaterials 2008 Feb 13;29(6):643-52. Epub 2007 Nov 13.

Department of Orthopaedic Surgery, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2007.10.031DOI Listing
February 2008

An AAOS-NIH symposium. Fracture repair: challenges, opportunities, and directions for future research.

J Bone Joint Surg Am 2008 Feb;90(2):438-42

Department of Orthopaedic Surgery, Boston University Medical Center, 720 Harrison Avenue, Suite 808, Boston, MA 02118, USA.

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http://dx.doi.org/10.2106/JBJS.G.01092DOI Listing
February 2008

Fracture repair: challenges and opportunities.

J Bone Joint Surg Am 2008 Feb;90 Suppl 1:1-2

Department of Orthopaedic Surgery, University of Virginia, 400 Ray C. Hunt Drive, Suite 330, Charlottesville, VA 22903, USA.

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http://dx.doi.org/10.2106/JBJS.G.01605DOI Listing
February 2008

Tissue engineering of bone: material and matrix considerations.

J Bone Joint Surg Am 2008 Feb;90 Suppl 1:36-42

University of Virginia School of Medicine, 400 Ray C. Hunt Drive, Charlottesville, VA 22908, USA.

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https://insights.ovid.com/crossref?an=00004623-200802001-000
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http://dx.doi.org/10.2106/JBJS.G.01260DOI Listing
February 2008

Nanofibers and nanoparticles for orthopaedic surgery applications.

J Bone Joint Surg Am 2008 Feb;90 Suppl 1:128-31

Department of Orthopaedic Surgery, University of Virginia, 415 LaneRoad, Box 800759, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.2106/JBJS.G.01520DOI Listing
February 2008

Fracture repair with ultrasound: clinical and cell-based evaluation.

J Bone Joint Surg Am 2008 Feb;90 Suppl 1:138-44

Department of Orthopaedic Surgery, University of Virginia School of Medicine, Hospital Drive, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.2106/JBJS.G.01218DOI Listing
February 2008

Xenotransplantation in orthopaedic surgery.

J Am Acad Orthop Surg 2008 Jan;16(1):4-8

Department of Orthopaedic Surgery, The University of Virginia, Charlottesville, VA, 22903, USA.

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January 2008

HIV/AIDS and the African-American community: a state of emergency.

J Natl Med Assoc 2008 Jan;100(1):35-43

Department of Orthopaedic Surgery, University of Virginia, Charlottesville, VA 22903, USA.

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January 2008

Development of injectable thermogelling chitosan-inorganic phosphate solutions for biomedical applications.

Biomacromolecules 2007 Dec 10;8(12):3779-85. Epub 2007 Nov 10.

Department of Orthopaedic Surgery, University of Virginia, Virginia 22903, USA.

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http://dx.doi.org/10.1021/bm7006967DOI Listing
December 2007

Novel biodegradable poly(1,8-octanediol malate) for annulus fibrosus regeneration.

Macromol Biosci 2007 Nov;7(11):1217-24

Department of Orthopaedic Surgery, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1002/mabi.200700053DOI Listing
November 2007

Cato T. Laurencin, MD, PhD.

Authors:
Cato T Laurencin

J Natl Med Assoc 2007 Nov;99(11):1286-7

University of Virginia, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574318PMC
November 2007