Publications by authors named "Cathryn M Gould"

25Publications

DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns.

Cancer Cell 2019 02;35(2):297-314.e8

Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, 384 Victoria St, Sydney, NSW 2010, Australia; St Vincent's Clinical School, UNSW, Sydney, NSW 2010, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2019.01.004DOI Listing
February 2019

Discovering cancer vulnerabilities using high-throughput micro-RNA screening.

Nucleic Acids Res 2017 Dec;45(22):12657-12670

The Kinghorn Cancer Centre & Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkx1072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728403PMC
December 2017

Comprehensive evaluation of genome-wide 5-hydroxymethylcytosine profiling approaches in human DNA.

Epigenetics Chromatin 2017 20;10:16. Epub 2017 Apr 20.

Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010 Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13072-017-0123-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397694PMC
January 2018

Systematic high-content genome-wide RNAi screens of endothelial cell migration and morphology.

Sci Data 2017 03 1;4:170009. Epub 2017 Mar 1.

Tumour Angiogenesis Program, Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, Victoria 3000, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sdata.2017.9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332011PMC
March 2017

Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations.

Genome Res 2016 06 6;26(6):719-31. Epub 2016 Apr 6.

Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; St. Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Darlinghurst, New South Wales 2010, Australia;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.201517.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889976PMC
June 2016

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma.

Clin Cancer Res 2015 Jul 10;21(14):3216-29. Epub 2015 Apr 10.

St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia. Department of Medicine, St. Vincent's Hospital, University of Melbourne, Fitzroy, Victoria, Australia. ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-14-3026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506243PMC
July 2015

Synthetic Lethal Screens Identify Vulnerabilities in GPCR Signaling and Cytoskeletal Organization in E-Cadherin-Deficient Cells.

Mol Cancer Ther 2015 May 16;14(5):1213-23. Epub 2015 Mar 16.

Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-14-1092DOI Listing
May 2015

Whole-genome multiparametric screening to identify modulators of epithelial-to-mesenchymal transition.

Assay Drug Dev Technol 2014 Sep;12(7):385-94

1 University of Malaya , Kuala Lumpur, Malaysia .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/adt.2014.593DOI Listing
September 2014

Functional genomics down under: RNAi screening in the Victorian Centre for Functional Genomics.

Comb Chem High Throughput Screen 2014 May;17(4):343-55

Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1386207317666140323134315DOI Listing
May 2014

Genome-wide functional genomic and transcriptomic analyses for genes regulating sensitivity to vorinostat.

Sci Data 2014 8;1:140017. Epub 2014 Jul 8.

Victorian Centre for Functional Genomics, The Peter MacCallum Cancer Centre , St Andrews Place, East Melbourne, Victoria 3002, Australia ; Sir Peter MacCallum Department of Oncology, The University of Melbourne , Parkville, Victoria 3052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sdata.2014.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322586PMC
November 2015

A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation.

J Cell Sci 2013 Dec 17;126(Pt 23):5377-90. Epub 2013 Sep 17.

School of Biomedical Sciences, The University of Queensland, St. Lucia, Queensland, 4072, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.128280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843137PMC
December 2013

Phospho.ELM: a database of phosphorylation sites--update 2011.

Nucleic Acids Res 2011 Jan 9;39(Database issue):D261-7. Epub 2010 Nov 9.

SCB Unit, EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkq1104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013696PMC
January 2011

A structure filter for the Eukaryotic Linear Motif Resource.

BMC Bioinformatics 2009 Oct 24;10:351. Epub 2009 Oct 24.

Center for Molecular Bioinformatics, Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2105-10-351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774702PMC
October 2009

A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences.

BMC Bioinformatics 2008 May 6;9:229. Epub 2008 May 6.

EMBL Structural and Computational Biology Unit, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
Publisher Site
http://dx.doi.org/10.1186/1471-2105-9-229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396637PMC
May 2008

Phospho.ELM: a database of phosphorylation sites--update 2008.

Nucleic Acids Res 2008 Jan 25;36(Database issue):D240-4. Epub 2007 Oct 25.

Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.

View Article

Download full-text PDF

Source
https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
Publisher Site
http://dx.doi.org/10.1093/nar/gkm772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238828PMC
January 2008