Cathrin Brisken

Cathrin Brisken

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Cathrin Brisken

Cathrin Brisken

Publications by authors named "Cathrin Brisken"

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A high resolution LC-MS targeted method for the concomitant analysis of 11 contraceptive progestins and 4 steroids.

J Pharm Biomed Anal 2019 Oct 25;175:112756. Epub 2019 Jul 25.

Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole polytechnique fédérale de Lausanne (EPFL), CH-1015, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2019.07.004DOI Listing
October 2019

Two-Tier Mapper, an unbiased topology-based clustering method for enhanced global gene expression analysis.

Bioinformatics 2019 Sep;35(18):3339-3347

School of Life Sciences, Swiss Institute for Experimental Cancer Research, Ecole Polytechnique Fédérale de Lausanne, Lausanne CH-1015, Switzerland.

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http://dx.doi.org/10.1093/bioinformatics/btz052DOI Listing
September 2019

Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium.

Nat Commun 2018 11 9;9(1):4723. Epub 2018 Nov 9.

Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, CH-1015, Lausanne, Switzerland.

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http://www.nature.com/articles/s41467-018-07175-0
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http://dx.doi.org/10.1038/s41467-018-07175-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226531PMC
November 2018

The challenges of modeling hormone receptor-positive breast cancer in mice.

Endocr Relat Cancer 2018 05 21;25(5):R319-R330. Epub 2018 Mar 21.

International Cancer Prevention Institute, Epalinges, Switzerland.

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http://dx.doi.org/10.1530/ERC-18-0063DOI Listing
May 2018

Analysis of Mammary Gland Phenotypes by Transplantation of the Genetically Marked Mammary Epithelium.

Methods Mol Biol 2017 ;1501:115-129

The Swiss Institute for Experimental Cancer Research (ISREC), Swiss Federal Institute of Technology (EPFL), Station 19, CH-1015, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/978-1-4939-6475-8_4DOI Listing
January 2018

reprogramming of non-mammary cells to an epithelial cell fate is independent of amphiregulin signaling.

J Cell Sci 2017 Jun 28;130(12):2018-2025. Epub 2017 Apr 28.

Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

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http://dx.doi.org/10.1242/jcs.200030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482980PMC
June 2017

Endocrine hormones and local signals during the development of the mouse mammary gland.

Wiley Interdiscip Rev Dev Biol 2015 May-Jun;4(3):181-95. Epub 2015 Jan 23.

ISREC - Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

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http://dx.doi.org/10.1002/wdev.172DOI Listing
March 2016

A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response.

Cancer Cell 2016 Mar 3;29(3):407-422. Epub 2016 Mar 3.

ISREC - Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole polytechnique fédérale de Lausanne (EPFL), SV2.832 Station 19, 1015 Lausanne, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15356108163003
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http://dx.doi.org/10.1016/j.ccell.2016.02.002DOI Listing
March 2016

Progesterone and Overlooked Endocrine Pathways in Breast Cancer Pathogenesis.

Endocrinology 2015 Oct 4;156(10):3442-50. Epub 2015 Aug 4.

Swiss Institute for Experimental Cancer Research (C.B., R.J.) and Brain and Mind Institute (K.H.), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1210/en.2015-1392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588833PMC
October 2015

Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalk.

EMBO J 2015 Mar 20;34(5):641-52. Epub 2015 Jan 20.

Ecole Polytechnique Fédérale de Lausanne (EPFL) ISREC - Swiss Institute for Experimental Cancer Research, Lausanne, Switzerland

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http://dx.doi.org/10.15252/embj.201490434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365033PMC
March 2015

An ex vivo model to study hormone action in the human breast.

J Vis Exp 2015 Jan 8(95):e52436. Epub 2015 Jan 8.

Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole polytechnique fédérale de Lausanne;

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http://dx.doi.org/10.3791/52436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354520PMC
January 2015

Reply to Is progesterone a neutral or protective factor for breast cancer?

Authors:
Cathrin Brisken

Nat Rev Cancer 2014 Feb 20;14(2):146. Epub 2014 Jan 20.

ISREC - Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), SV2.832 Station 19, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1038/nrc3518-c2DOI Listing
February 2014

Monitoring proliferative activities of hormone-like odorants in human breast cancer cells by gene transcription profiling and electrical impedance spectroscopy.

Biosens Bioelectron 2013 Dec 4;50:431-6. Epub 2013 Jul 4.

Laboratory of Physical Chemistry of Polymers and Membranes, Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bios.2013.06.052DOI Listing
December 2013

Progesterone signalling in breast cancer: a neglected hormone coming into the limelight.

Authors:
Cathrin Brisken

Nat Rev Cancer 2013 Jun;13(6):385-96

ISREC - Swiss Institute for Experimental Cancer Research, National Center of Competence for Molecular Oncology, School of Life Sciences, Ecole polytechnique fédérale de Lausanne (EPFL), SV2.832 Station 19, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1038/nrc3518DOI Listing
June 2013

Progesterone/RANKL is a major regulatory axis in the human breast.

Sci Transl Med 2013 Apr;5(182):182ra55

Swiss Institute for Experimental Cancer Research, National Center of Competence in Research Molecular Oncology, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1126/scitranslmed.3005654DOI Listing
April 2013

Paracrine signaling by progesterone.

Mol Cell Endocrinol 2012 Jun 16;357(1-2):80-90. Epub 2011 Sep 16.

Ecole Polytechnique Fédérale de Lausanne, ISREC - Swiss Institute for Experimental Cancer Research, NCCR Molecular Oncology, SV2832 Station 19, CH-1015 Lausanne, Switzerland.

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http://infoscience.epfl.ch/record/178405/files/Paracrine%20s
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http://linkinghub.elsevier.com/retrieve/pii/S030372071100552
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http://dx.doi.org/10.1016/j.mce.2011.09.018DOI Listing
June 2012

Perinatal exposure to bisphenol a increases adult mammary gland progesterone response and cell number.

Mol Endocrinol 2011 Nov 8;25(11):1915-23. Epub 2011 Sep 8.

ISREC-Swiss Institute for Experimental Cancer Research, National Center of Competence Molecular Oncology, Lausanne, Switzerland.

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http://dx.doi.org/10.1210/me.2011-1129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417179PMC
November 2011

High hopes for RANKL: will the mouse model live up to its promise?

Breast Cancer Res 2011 Jan 28;13(1):302. Epub 2011 Jan 28.

Ecole polytechnique fédérale de Lausanne, ISREC - Swiss Institute for Experimental Cancer Research, NCCR Molecular Oncology, SV2,832 Station 19, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1186/bcr2805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109567PMC
January 2011

Hormone action in the mammary gland.

Cold Spring Harb Perspect Biol 2010 Dec 25;2(12):a003178. Epub 2010 Aug 25.

Ecole Polytechnique Fédérale de Lausanne (EPFL), ISREC - Swiss institute for experimental cancer research, NCCR Molecular Oncology, SV2.832 Station 19, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1101/cshperspect.a003178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982168PMC
December 2010

From normal cell types to malignant phenotypes.

Breast Cancer Res 2009 9;11(6):306. Epub 2009 Nov 9.

Ecole polytechnique fédérale de Lausanne, ISREC - Swiss Institute for Experimental Cancer Research, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1186/bcr2418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815539PMC
July 2010

Cyclin D1 enhances the response to estrogen and progesterone by regulating progesterone receptor expression.

Mol Cell Biol 2010 Jun 19;30(12):3111-25. Epub 2010 Apr 19.

Cancer Research Center at Massachusetts General Hospital, 55 Fruit Street, GRJ 9th floor, Boston, MA 02114, USA.

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http://dx.doi.org/10.1128/MCB.01398-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876668PMC
June 2010

Stem cells in chemical carcinogenesis.

Arch Toxicol 2010 Mar 26;84(3):245-51. Epub 2009 Nov 26.

Institute of Toxicology, University Medical Centre, Johannes Gutenberg-University, Mainz, Germany.

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http://link.springer.com/10.1007/s00204-009-0491-2
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http://dx.doi.org/10.1007/s00204-009-0491-2DOI Listing
March 2010

Amphiregulin mediates self-renewal in an immortal mammary epithelial cell line with stem cell characteristics.

Exp Cell Res 2010 Feb 12;316(3):422-32. Epub 2009 Nov 12.

Mammary Biology and Tumorigenesis Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.yexcr.2009.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812656PMC
February 2010

Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland.

Proc Natl Acad Sci U S A 2010 Feb 28;107(7):2989-94. Epub 2010 Jan 28.

Ecole Polytechnique Fédérale de Lausanne, Swiss Institute for Experimental Cancer Research (ISREC), NCCR Molecular Oncology, CH-1015 Lausanne, Switzerland.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0915148107
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http://dx.doi.org/10.1073/pnas.0915148107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840294PMC
February 2010

What signals operate in the mammary niche?

Breast Dis 2008 ;29:69-82

NCCR Molecular Oncology, Ecole polytechnique fédérale de Lausanne (EPFL), ISREC-Swiss Institute for Experimental Cancer Research, 155, Chemin des Boveresses, CH-1066 Epalinges, Switzerland.

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http://dx.doi.org/10.3233/bd-2008-29108DOI Listing
February 2009

Epidermal receptor activator of NF-kappaB ligand controls Langerhans cells numbers and proliferation.

J Immunol 2008 Jul;181(2):1103-8

St John's Institute of Dermatology, King's College London, London, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.181.2.1103DOI Listing
July 2008

An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells.

Breast Cancer Res 2007 ;9(3):R38

NCCR Molecular Oncology, Swiss Institute for Experimental Cancer Research (ISREC), Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland.

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http://dx.doi.org/10.1186/bcr1734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929103PMC
September 2007

Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective.

Stem Cell Rev 2007 Jun;3(2):147-56

NCCR Molecular Oncology, Swiss Institute for Experimental Cancer Research (ISREC), 155 Chemin des Boveresses, Epalinges s/Lausanne, CH 1066, Switzerland.

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http://dx.doi.org/10.1007/s12015-007-0019-1DOI Listing
June 2007

Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development.

Proc Natl Acad Sci U S A 2007 Mar 16;104(13):5455-60. Epub 2007 Mar 16.

Swiss Institute for Experimental Cancer Research, National Center of Competence in Research, Molecular Oncology, Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0611647104
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http://dx.doi.org/10.1073/pnas.0611647104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838509PMC
March 2007

Alveolar and lactogenic differentiation.

J Mammary Gland Biol Neoplasia 2006 Oct;11(3-4):239-48

National Center of Competence in Research (NCCR) Molecular Oncology, Swiss Institute for Experimental Cancer Research (ISREC), 155 Chemin des Boveresses, CH-1066, Epalinges, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/s10911-006-9026-0DOI Listing
October 2006

Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism.

Proc Natl Acad Sci U S A 2006 Mar 24;103(10):3799-804. Epub 2006 Feb 24.

Swiss Institute for Experimental Cancer Research, National Center of Competence in Research in Molecular Oncology, 155 Chemin des Boveresses, CH-1066 Epalinges/Lausanne, Switzerland.

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http://dx.doi.org/10.1073/pnas.0600065103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450156PMC
March 2006

Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland.

Proc Natl Acad Sci U S A 2006 Feb 1;103(7):2196-201. Epub 2006 Feb 1.

National Center of Competence in Research Molecular Oncology, Swiss Institute for Experimental Cancer Research, 155 Chemin des Boveresses, CH-1066 Epalinges s/Lausanne, Switzerland.

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http://dx.doi.org/10.1073/pnas.0510974103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413744PMC
February 2006

Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis.

Development 2004 Oct 1;131(19):4819-29. Epub 2004 Sep 1.

Departments of Dermatology and Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1242/dev.01347DOI Listing
October 2004

Using gene expression arrays to elucidate transcriptional profiles underlying prolactin function.

J Mammary Gland Biol Neoplasia 2003 Jul;8(3):269-85

Swiss Institute for Experimental Cancer Research, National Center of Competence in Research Molecular Oncology, Epalinges s/Lausanne, Switzerland.

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http://dx.doi.org/10.1023/b:jomg.0000010029.85796.63DOI Listing
July 2003

Prolactin signaling and Stat5: going their own separate ways?

Breast Cancer Res 2002 3;4(6):209-12. Epub 2002 Oct 3.

Swiss Institute for Experimental Cancer Research, Epalinges, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137942PMC
http://dx.doi.org/10.1186/bcr543DOI Listing
April 2003

IGF-2 is a mediator of prolactin-induced morphogenesis in the breast.

Dev Cell 2002 Dec;3(6):877-87

Department of Surgical Oncology, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/s1534-5807(02)00365-9DOI Listing
December 2002

The signaling domain of the erythropoietin receptor rescues prolactin receptor-mutant mammary epithelium.

Proc Natl Acad Sci U S A 2002 Oct 15;99(22):14241-5. Epub 2002 Oct 15.

Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1073/pnas.222549599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137868PMC
October 2002

Hormonal control of alveolar development and its implications for breast carcinogenesis.

Authors:
Cathrin Brisken

J Mammary Gland Biol Neoplasia 2002 Jan;7(1):39-48

Surgical Oncology, MGH Cancer Center, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1023/a:1015718406329DOI Listing
January 2002