Cathie Pfleger

Cathie Pfleger

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Cathie Pfleger

Cathie Pfleger

Publications by authors named "Cathie Pfleger"

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The Power of Drosophila Genetics: The Discovery of the Hippo Pathway.

Methods Mol Biol 2019 ;1893:3-26

Department of Oncological Sciences, The Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-8910-2_1DOI Listing
June 2019

MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network.

Mol Cell 2019 05 14;74(3):452-465.e7. Epub 2019 Mar 14.

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; The Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499641PMC
May 2019

The Hippo Pathway: A Master Regulatory Network Important in Development and Dysregulated in Disease.

Authors:
Cathie M Pfleger

Curr Top Dev Biol 2017 19;123:181-228. Epub 2017 Jan 19.

The Icahn School of Medicine at Mount Sinai, New York, NY, United States; The Graduate School of Biomedical Sciences, The Icahn School of Medicine at Mount Sinai, New York, NY, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.ctdb.2016.12.001DOI Listing
May 2017

Methods to Examine the Lymph Gland and Hemocytes in Drosophila Larvae.

J Vis Exp 2016 11 28(117). Epub 2016 Nov 28.

The Graduate School of Biomedical Sciences, The Icahn School of Medicine at Mount Sinai; Department of Oncological Sciences, The Icahn School of Medicine at Mount Sinai;

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http://dx.doi.org/10.3791/54544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226300PMC
November 2016

The Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin, Hippo, and Warts.

PLoS Genet 2016 08 5;12(8):e1006198. Epub 2016 Aug 5.

Department of Oncological Sciences, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975479PMC
August 2016

Combover/CG10732, a novel PCP effector for Drosophila wing hair formation.

PLoS One 2014 10;9(9):e107311. Epub 2014 Sep 10.

Department of Developmental and Molecular Biology and Department of Genetics, Albert Einstein College of Medicine, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107311PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160248PMC
March 2016

Drosophila Rabex-5 restricts Notch activity in hematopoietic cells and maintains hematopoietic homeostasis.

J Cell Sci 2015 Dec 13;128(24):4512-25. Epub 2015 Nov 13.

Department of Oncological Sciences, The Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA The Graduate School of Biomedical Sciences, The Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA

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http://dx.doi.org/10.1242/jcs.174433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696494PMC
December 2015

Alcohol interacts with genetic alteration of the Hippo tumor suppressor pathway to modulate tissue growth in Drosophila.

PLoS One 2013 21;8(10):e78880. Epub 2013 Oct 21.

Department of Oncological Sciences, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America ; Yale University, New Haven, Connecticut, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078880PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804493PMC
August 2014

Mutation in E1, the ubiquitin activating enzyme, reduces Drosophila lifespan and results in motor impairment.

PLoS One 2013 29;8(1):e32835. Epub 2013 Jan 29.

Department of Oncological Sciences, The Mount Sinai School of Medicine, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0032835PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558519PMC
September 2013

Mono-ubiquitination drives nuclear export of the human DCN1-like protein hDCNL1.

J Biol Chem 2011 Sep 3;286(39):34060-70. Epub 2011 Aug 3.

Department of Oncological Sciences, The Mount Sinai School of Medicine, New York, New York 10029-6574, USA.

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http://www.jbc.org/content/early/2011/08/03/jbc.M111.273045.
Web Search
http://www.jbc.org/cgi/doi/10.1074/jbc.M111.273045
Publisher Site
http://dx.doi.org/10.1074/jbc.M111.273045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190805PMC
September 2011

Ubiquitin on ras: warden or partner in crime?

Authors:
Cathie M Pfleger

Sci Signal 2011 Mar 8;4(163):pe12. Epub 2011 Mar 8.

Department of Oncological Sciences, The Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1126/scisignal.2001874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495660PMC
March 2011

Recent efforts to model human diseases in vivo in Drosophila.

Fly (Austin) 2008 May-Jun;2(3):129-32. Epub 2008 May 23.

Department of Oncological Sciences, The Mount Sinai School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.4161/fly.6332DOI Listing
December 2010

Rabex-5 ubiquitin ligase activity restricts Ras signaling to establish pathway homeostasis in Drosophila.

Curr Biol 2010 Aug 22;20(15):1378-82. Epub 2010 Jul 22.

Department of Oncological Sciences, The Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.cub.2010.06.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938185PMC
August 2010

Grape-seed polyphenolic extract improves the eye phenotype in a Drosophila model of tauopathy.

Int J Alzheimers Dis 2010 Aug 24;2010. Epub 2010 Aug 24.

Department of Oncological Sciences, Mount Sinai School of Medicine, One Gustave L. Levy Place, NY 10029, USA.

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http://dx.doi.org/10.4061/2010/576357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943075PMC
August 2010

Mutation of the gene encoding the ubiquitin activating enzyme ubal causes tissue overgrowth in Drosophila.

Fly (Austin) 2007 Mar-Apr;1(2):95-105

Massachusetts General Hospital Canter Center, Massachusetts General Hospital, Chrlestown, Massachusetts, USA.

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http://dx.doi.org/10.4161/fly.4285DOI Listing
August 2009

Impairment of ubiquitylation by mutation in Drosophila E1 promotes both cell-autonomous and non-cell-autonomous Ras-ERK activation in vivo.

J Cell Sci 2009 May 14;122(Pt 9):1461-70. Epub 2009 Apr 14.

Department of Oncological Sciences, The Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1242/jcs.042267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721006PMC
May 2009

The Drosophila melanogaster Apaf-1 homologue ARK is required for most, but not all, programmed cell death.

J Cell Biol 2006 Mar;172(6):809-15

Hanson Institute, Institute of Medical and Veterinary Science, Adelaide, Australia 5000.

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http://dx.doi.org/10.1083/jcb.200512126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063725PMC
March 2006

The C-terminal domain of the Xenopus cyclin-dependent kinase inhibitor, p27Xic1, is both necessary and sufficient for phosphorylation-independent proteolysis.

J Biol Chem 2005 Oct 23;280(42):35290-8. Epub 2005 Aug 23.

Department of Molecular Medicine, Institute of Biotechnology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78245, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M506430200
Publisher Site
http://dx.doi.org/10.1074/jbc.M506430200DOI Listing
October 2005

The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis.

Cell 2003 Aug;114(4):457-67

Massachusetts General Hospital Cancer Center, Building 149, 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/s0092-8674(03)00557-9DOI Listing
August 2003

Mouse ribonucleotide reductase R2 protein: a new target for anaphase-promoting complex-Cdh1-mediated proteolysis.

Proc Natl Acad Sci U S A 2003 Apr 24;100(7):3925-9. Epub 2003 Mar 24.

Department of Medical Biochemistry and Biophysics, Umeå University, SE-901 87 Umeå, Sweden.

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http://dx.doi.org/10.1073/pnas.0330774100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153024PMC
April 2003