Publications by authors named "Catherine Orrell"

90Publications

Perceived oral health interventions by medical providers in Gugulethu, South Africa.

PLoS One 2020 26;15(5):e0233437. Epub 2020 May 26.

Center for Global Health, Massachusetts General Hospital, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233437PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250410PMC
August 2020

Influences on Adherence to Antiretroviral Therapy (ART) in Early-Stage HIV Disease: Qualitative Study from Uganda and South Africa.

AIDS Behav 2020 Sep;24(9):2624-2636

Deparment of Global Health and Social Medicine, Harvard Medical School, 641 Huntington Ave., Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s10461-020-02819-zDOI Listing
September 2020

Pharmacokinetic profile and safety of adjusted doses of darunavir/ritonavir with rifampicin in people living with HIV.

J Antimicrob Chemother 2020 Apr;75(4):1019-1025

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1093/jac/dkz522DOI Listing
April 2020

HIV viral resuppression following an elevated viral load: a systematic review and meta-analysis.

J Int AIDS Soc 2019 11;22(11):e25415

Department of HIV, World Health Organization, Geneva, Switzerland.

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http://dx.doi.org/10.1002/jia2.25415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864498PMC
November 2019

Transition to third-line ART in resource-limited settings.

Lancet HIV 2019 11 7;6(11):e725-e727. Epub 2019 Oct 7.

Desmond Tutu HIV Foundation and Centre, Institute of Infectious Disease and Molecular Medicine, and Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1016/S2352-3018(19)30324-8DOI Listing
November 2019

Correlation of hair and plasma efavirenz concentrations in HIV-positive South Africans.

South Afr J HIV Med 2019 29;20(1):881. Epub 2019 Apr 29.

Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Cape Town, South Africa.

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https://sajhivmed.org.za/index.php/hivmed/article/view/881
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http://dx.doi.org/10.4102/sajhivmed.v20i1.881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494950PMC
April 2019

Recreational ART use among individuals living with HIV/AIDS in South Africa: Examining longitudinal ART initiation and viral suppression.

Drug Alcohol Depend 2019 05 22;198:192-198. Epub 2019 Mar 22.

Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA; Massachusetts General Hospital Center for Global Health, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644059PMC
May 2019

Decreases in Self-Reported ART Adherence Predict HIV Viremia Among Pregnant and Postpartum South African Women.

2019 03;80(3):247-254

Division of Epidemiology and Biostatistics, Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1097/QAI.0000000000001909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375758PMC
March 2019

Linkage to care, mobility and retention of HIV-positive postpartum women in antiretroviral therapy services in South Africa.

J Int AIDS Soc 2018 07;21 Suppl 4:e25114

Division of Epidemiology & Biostatistics, Centre for Infectious Disease Epidemiology & Research, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1002/jia2.25114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053482PMC
July 2018

Comparison of six methods to estimate adherence in an ART-naïve cohort in a resource-poor setting: which best predicts virological and resistance outcomes?

AIDS Res Ther 2017 Apr 4;14(1):20. Epub 2017 Apr 4.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1186/s12981-017-0138-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379739PMC
April 2017

Factors that Motivated Otherwise Healthy HIV-Positive Young Adults to Access HIV Testing and Treatment in South Africa.

AIDS Behav 2018 03;22(3):733-741

Center for Global Health, Massachusetts General Hospital, 125 Nashua St, Suite 722, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s10461-017-1704-yDOI Listing
March 2018

Effect of mid-dose efavirenz concentrations and CYP2B6 genotype on viral suppression in patients on first-line antiretroviral therapy.

Int J Antimicrob Agents 2016 Jun 4;47(6):466-72. Epub 2016 May 4.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1016/j.ijantimicag.2016.03.017DOI Listing
June 2016

CD4 count at antiretroviral therapy initiation and the risk of loss to follow-up: results from a multicentre cohort study.

J Epidemiol Community Health 2016 06 23;70(6):549-55. Epub 2015 Dec 23.

Division of Epidemiology and Biostatistics, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa Centre for Infectious Disease Epidemiology & Research, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1136/jech-2015-206629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865447PMC
June 2016

A Randomized Controlled Trial of Real-Time Electronic Adherence Monitoring With Text Message Dosing Reminders in People Starting First-Line Antiretroviral Therapy.

2015 Dec;70(5):495-502

*Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Cape Town, South Africa; †Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa; ‡Department of Statistical Science, University of Cape Town, Cape Town, South Africa; §Harvard Medical School, Boston, MA; ‖Massachusetts General Hospital Center for Global Health, Boston, MA; and ¶Ragon Institute of Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000000770DOI Listing
December 2015

Limited use for dual treatment with boosted protease inhibitors plus lamivudine in first-line antiretroviral therapy.

Lancet Infect Dis 2015 Jul 7;15(7):748-9. Epub 2015 Jun 7.

Desmond Tutu HIV Foundation, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7925, South Africa.

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http://dx.doi.org/10.1016/S1473-3099(15)00098-5DOI Listing
July 2015

Rates of switching antiretroviral drugs in a primary care service in South Africa before and after introduction of tenofovir.

PLoS One 2013 22;8(5):e63596. Epub 2013 May 22.

Desmond Tutu HIV Centre, Institute for Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063596PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661537PMC
April 2014

Increasing transfers-out from an antiretroviral treatment service in South Africa: patient characteristics and rates of virological non-suppression.

PLoS One 2013 5;8(3):e57907. Epub 2013 Mar 5.

The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, and the Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0057907PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589459PMC
December 2013

Antiretroviral therapy adherence support: recommendations and future directions.

J Int Assoc Provid AIDS Care 2013 Mar-Apr;12(2):128-37. Epub 2013 Jan 18.

Center for Health, Intervention and Prevention, University of Connecticut, Storrs, CT 06269, USA.

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http://dx.doi.org/10.1177/1545109712459041DOI Listing
August 2013

Resistance in pediatric patients experiencing virologic failure with first-line and second-line antiretroviral therapy.

Pediatr Infect Dis J 2013 Jun;32(6):644-7

Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town Faculty of Health Sciences, Cape Town, South Africa.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/INF.0b013e3182829092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881960PMC
June 2013

Virological breakthrough: a risk factor for loss to followup in a large community-based cohort on antiretroviral therapy.

AIDS Res Treat 2011 8;2011:469127. Epub 2011 May 8.

Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Cape Town 7925, South Africa.

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http://dx.doi.org/10.1155/2011/469127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119419PMC
July 2011

Pharmacokinetics of lopinavir in HIV-infected adults receiving rifampin with adjusted doses of lopinavir-ritonavir tablets.

Antimicrob Agents Chemother 2011 Jul 2;55(7):3195-200. Epub 2011 May 2.

Division of Clinical Pharmacology, Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.

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http://aac.asm.org/lookup/doi/10.1128/AAC.01598-10
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http://dx.doi.org/10.1128/AAC.01598-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122443PMC
July 2011

Effect of caregivers' depression and alcohol use on child antiretroviral adherence in South Africa.

AIDS Patient Care STDS 2011 Oct 6;25(10):595-600. Epub 2011 Apr 6.

Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1089/apc.2010.0323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183652PMC
October 2011

Changes in programmatic outcomes during 7 years of scale-up at a community-based antiretroviral treatment service in South Africa.

2011 Jan;56(1):e1-8

The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1097/QAI.0b013e3181ff0bdcDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776048PMC
January 2011

Linkage to HIV care and antiretroviral therapy in Cape Town, South Africa.

PLoS One 2010 Nov 2;5(11):e13801. Epub 2010 Nov 2.

Department of Medicine, Faculty of Health Sciences, The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013801PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970551PMC
November 2010

HIV type-1 clade C resistance genotypes in treatment-naive patients and after first virological failure in a large community antiretroviral therapy programme.

Antivir Ther 2009 ;14(4):523-31

Desmond Tutu HIV Foundation, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211093PMC
August 2009

Changing mortality risk associated with CD4 cell response to antiretroviral therapy in South Africa.

AIDS 2009 Jan;23(3):335-42

The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, University of Cape Town, South Africa.

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http://dx.doi.org/10.1097/QAD.0b013e328321823fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776050PMC
January 2009

Loss to follow-up and mortality among pregnant women referred to a community clinic for antiretroviral treatment.

AIDS 2008 Aug;22(13):1679-81

The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1097/QAD.0b013e32830ebceeDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741732PMC
August 2008

Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers.

Eur J Clin Pharmacol 2008 Jul 16;64(7):683-90. Epub 2008 Apr 16.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Anzio Road, Observatory, Cape Town, 7925, South Africa.

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http://link.springer.com/10.1007/s00228-007-0452-8
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http://dx.doi.org/10.1007/s00228-007-0452-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426925PMC
July 2008

Healthcare utilization of patients accessing an African national treatment program.

BMC Health Serv Res 2007 Jun 7;7:80. Epub 2007 Jun 7.

The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa.

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http://dx.doi.org/10.1186/1472-6963-7-80DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899174PMC
June 2007

Conservation of first-line antiretroviral treatment regimen where therapeutic options are limited.

Antivir Ther 2007 ;12(1):83-8

The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa.

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June 2007

Determinants of mortality and nondeath losses from an antiretroviral treatment service in South Africa: implications for program evaluation.

Clin Infect Dis 2006 Sep 8;43(6):770-6. Epub 2006 Aug 8.

The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1086/507095DOI Listing
September 2006

Rapid scale-up of a community-based HIV treatment service: programme performance over 3 consecutive years in Guguletu, South Africa.

S Afr Med J 2006 Apr;96(4):315-20

Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, University of Cape Town.

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April 2006

When to initiate highly active antiretroviral therapy in sub-Saharan Africa? A South African cost-effectiveness study.

Antivir Ther 2006 ;11(1):63-72

Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Department of Medicine, University of Cape Town, South Africa.

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April 2006

Antiretroviral adherence in a resource-poor setting.

Authors:
Catherine Orrell

Curr HIV/AIDS Rep 2005 Nov;2(4):171-6

Desmond Tutu HIV Centre, IIDMM, Werner Beit Building-North, Medical School, Anzio Road, Observatory, Cape Town 7925, South Africa.

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http://dx.doi.org/10.1007/s11904-005-0012-8DOI Listing
November 2005

Early mortality among adults accessing a community-based antiretroviral service in South Africa: implications for programme design.

AIDS 2005 Dec;19(18):2141-8

The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Cape Town, South Africa.

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http://dx.doi.org/10.1097/01.aids.0000194802.89540.e1DOI Listing
December 2005

Initiating highly active antiretroviral therapy in sub-Saharan Africa: an assessment of the revised World Health Organization scaling-up guidelines.

AIDS 2004 May;18(8):1159-68

Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Department of Medicine, University of Cape Town, Observatory, South Africa.

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http://dx.doi.org/10.1097/00002030-200405210-00009DOI Listing
May 2004

Antiretroviral therapy in a community clinic--early lessons from a pilot project.

S Afr Med J 2003 Jun;93(6):458-62

HIV Research Unit, University of Cape Town, Provincial Administration of the Western Cape.

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June 2003

Adherence is not a barrier to successful antiretroviral therapy in South Africa.

AIDS 2003 Jun;17(9):1369-75

Diana, Princess of Wales HIV Research Unit, Somerset Hospital, University of Cape Town, South Africa.

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http://dx.doi.org/10.1097/00002030-200306130-00011DOI Listing
June 2003