Publications by authors named "Catherine L Worth"

33Publications

GPCR-SSFE 2.0-a fragment-based molecular modeling web tool for Class A G-protein coupled receptors.

Nucleic Acids Res 2017 07;45(W1):W408-W415

Department of Structural Biology, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), D-13125 Berlin, Germany.

View Article and Find Full Text PDF
July 2017

Residues of a proposed gate region in type I ATP-binding cassette import systems are crucial for function as revealed by mutational analysis.

Biochim Biophys Acta 2013 Sep 6;1828(9):2164-72. Epub 2013 Jun 6.

Institut für Biologie/Bakterienphysiologie, Humboldt Universität zu Berlin, Chausseestr. 117, D-10115 Berlin, Germany.

View Article and Find Full Text PDF
September 2013

Binding sites in membrane proteins--diversity, druggability and prospects.

Eur J Cell Biol 2012 Apr 27;91(4):326-39. Epub 2011 Aug 27.

Charité-Universitätsklinikum Berlin, Structural Bioinformatics Group, Lindenberger Weg 80, 13125 Berlin, Germany.

View Article and Find Full Text PDF
April 2012

GPCR-SSFE: a comprehensive database of G-protein-coupled receptor template predictions and homology models.

BMC Bioinformatics 2011 May 23;12:185. Epub 2011 May 23.

Leibniz-Institut für Molekulare Pharmakologie, 13125 Berlin, Germany.

View Article and Find Full Text PDF
May 2011

SDM--a server for predicting effects of mutations on protein stability and malfunction.

Nucleic Acids Res 2011 Jul 18;39(Web Server issue):W215-22. Epub 2011 May 18.

Biochemistry Department, University of Cambridge, Cambridge CB2 1GA, UK.

View Article and Find Full Text PDF
July 2011

Meet me halfway: when genomics meets structural bioinformatics.

J Cardiovasc Transl Res 2011 Jun 25;4(3):281-303. Epub 2011 Feb 25.

Biocomputing Group, Department of Biochemistry, University of Cambridge, UK.

View Article and Find Full Text PDF
June 2011

Research resource: Update and extension of a glycoprotein hormone receptors web application.

Mol Endocrinol 2011 Apr 3;25(4):707-12. Epub 2011 Feb 3.

Leibniz-Institut für Molekulare Pharmakologie, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.

View Article and Find Full Text PDF
April 2011

FragmentStore--a comprehensive database of fragments linking metabolites, toxic molecules and drugs.

Nucleic Acids Res 2011 Jan 21;39(Database issue):D1049-54. Epub 2010 Oct 21.

Charité-University Medicine Berlin, Institute of Physiology, Structural Bioinformatics Group, Lindenberger Weg 80, 13125 Berlin, Germany.

View Article and Find Full Text PDF
January 2011

SuperSweet--a resource on natural and artificial sweetening agents.

Nucleic Acids Res 2011 Jan 14;39(Database issue):D377-82. Epub 2010 Oct 14.

Charité - Universitätsmedizin Berlin, Institute of Physiology, Structural Bioinformatics Group, Lindenberger Weg 80, 13125 Berlin, Germany.

View Article and Find Full Text PDF
January 2011

On the evolutionary conservation of hydrogen bonds made by buried polar amino acids: the hidden joists, braces and trusses of protein architecture.

BMC Evol Biol 2010 May 31;10:161. Epub 2010 May 31.

Biocomputing Group, Biochemistry Department, University of Cambridge, Cambridge, CB2 1GA, UK.

View Article and Find Full Text PDF
May 2010

Comparative sequence and structural analyses of G-protein-coupled receptor crystal structures and implications for molecular models.

PLoS One 2009 Sep 16;4(9):e7011. Epub 2009 Sep 16.

Leibniz-Institut für Molekulare Pharmakologie (FMP), Berlin, Germany.

View Article and Find Full Text PDF
September 2009

Structural and functional constraints in the evolution of protein families.

Nat Rev Mol Cell Biol 2009 Oct 16;10(10):709-20. Epub 2009 Sep 16.

Biochemistry Department, University of Cambridge, UK.

View Article and Find Full Text PDF
October 2009

Structural and functional restraints in the evolution of protein families and superfamilies.

Biochem Soc Trans 2009 Aug;37(Pt 4):727-33

Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, UK.

View Article and Find Full Text PDF
August 2009

Satisfaction of hydrogen-bonding potential influences the conservation of polar sidechains.

Proteins 2009 May;75(2):413-29

Biochemistry Department, University of Cambridge, Cambridge, United Kingdom.

View Article and Find Full Text PDF
May 2009

AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity.

J Biol Chem 2008 Jan 1;283(3):1723-31. Epub 2007 Nov 1.

Department of Pathology, Divisions of Immunology and Cellular Pathology, University of Cambridge, Tennis Court Road, Cambridge, United Kingdom.

View Article and Find Full Text PDF
January 2008

Genome bioinformatic analysis of nonsynonymous SNPs.

BMC Bioinformatics 2007 Aug 20;8:301. Epub 2007 Aug 20.

Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK.

View Article and Find Full Text PDF
August 2007

PDBLIG: classification of small molecular protein binding in the Protein Data Bank.

J Med Chem 2004 Jul;47(15):3807-16

Department of Molecular Design, Inpharmatica, 60 Charlotte Street, London W1T 2NU, U.K.

View Article and Find Full Text PDF
July 2004