Catherine L Worth

Catherine L Worth

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Catherine L Worth

Catherine L Worth

Publications by authors named "Catherine L Worth"

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The Translational Landscape of the Human Heart.

Cell 2019 Jun 30;178(1):242-260.e29. Epub 2019 May 30.

Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, 13347 Berlin, Germany; Berlin Institute of Health (BIH), 10178 Berlin, Germany; Charité-Universitätsmedizin, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.05.010DOI Listing
June 2019

Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level.

Cell Mol Life Sci 2018 06 30;75(12):2227-2239. Epub 2017 Dec 30.

Institut für Experimentelle Pädiatrische Endokrinologie, Charité - Universitätsmedizin Berlin, 13353, Berlin, Germany.

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http://dx.doi.org/10.1007/s00018-017-2728-1DOI Listing
June 2018

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.

Nat Genet 2015 Sep 27;47(9):1020-1029. Epub 2015 Jul 27.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1038/ng.3362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603357PMC
September 2015

Residues of a proposed gate region in type I ATP-binding cassette import systems are crucial for function as revealed by mutational analysis.

Biochim Biophys Acta 2013 Sep 6;1828(9):2164-72. Epub 2013 Jun 6.

Institut für Biologie/Bakterienphysiologie, Humboldt Universität zu Berlin, Chausseestr. 117, D-10115 Berlin, Germany.

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http://dx.doi.org/10.1016/j.bbamem.2013.05.032DOI Listing
September 2013

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.

Nat Genet 2013 Aug 30;45(8):927-32. Epub 2013 Jun 30.

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://pubman.mpdl.mpg.de/pubman/item/escidoc:1982973/compon
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http://www.nature.com/doifinder/10.1038/ng.2682
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http://dx.doi.org/10.1038/ng.2682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951336PMC
August 2013

Binding sites in membrane proteins--diversity, druggability and prospects.

Eur J Cell Biol 2012 Apr 27;91(4):326-39. Epub 2011 Aug 27.

Charité-Universitätsklinikum Berlin, Structural Bioinformatics Group, Lindenberger Weg 80, 13125 Berlin, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S017193351100109
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http://dx.doi.org/10.1016/j.ejcb.2011.06.003DOI Listing
April 2012

SDM--a server for predicting effects of mutations on protein stability and malfunction.

Nucleic Acids Res 2011 Jul 18;39(Web Server issue):W215-22. Epub 2011 May 18.

Biochemistry Department, University of Cambridge, Cambridge CB2 1GA, UK.

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http://dx.doi.org/10.1093/nar/gkr363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125769PMC
July 2011

Meet me halfway: when genomics meets structural bioinformatics.

J Cardiovasc Transl Res 2011 Jun 25;4(3):281-303. Epub 2011 Feb 25.

Biocomputing Group, Department of Biochemistry, University of Cambridge, UK.

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http://dx.doi.org/10.1007/s12265-011-9259-1DOI Listing
June 2011

Research resource: Update and extension of a glycoprotein hormone receptors web application.

Mol Endocrinol 2011 Apr 3;25(4):707-12. Epub 2011 Feb 3.

Leibniz-Institut für Molekulare Pharmakologie, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.

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http://dx.doi.org/10.1210/me.2010-0510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417262PMC
April 2011

SuperSweet--a resource on natural and artificial sweetening agents.

Nucleic Acids Res 2011 Jan 14;39(Database issue):D377-82. Epub 2010 Oct 14.

Charité - Universitätsmedizin Berlin, Institute of Physiology, Structural Bioinformatics Group, Lindenberger Weg 80, 13125 Berlin, Germany.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkq917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013782PMC
January 2011

FragmentStore--a comprehensive database of fragments linking metabolites, toxic molecules and drugs.

Nucleic Acids Res 2011 Jan 21;39(Database issue):D1049-54. Epub 2010 Oct 21.

Charité-University Medicine Berlin, Institute of Physiology, Structural Bioinformatics Group, Lindenberger Weg 80, 13125 Berlin, Germany.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkq969DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013803PMC
January 2011

Structural bioinformatics mutation analysis reveals genotype-phenotype correlations in von Hippel-Lindau disease and suggests molecular mechanisms of tumorigenesis.

Proteins 2009 Oct;77(1):84-96

Biocomputing Group, Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, United Kingdom.

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http://dx.doi.org/10.1002/prot.22419DOI Listing
October 2009

Structural and functional constraints in the evolution of protein families.

Nat Rev Mol Cell Biol 2009 Oct 16;10(10):709-20. Epub 2009 Sep 16.

Biochemistry Department, University of Cambridge, UK.

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http://dx.doi.org/10.1038/nrm2762DOI Listing
October 2009

Structural and functional restraints in the evolution of protein families and superfamilies.

Biochem Soc Trans 2009 Aug;37(Pt 4):727-33

Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, UK.

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http://biochemsoctrans.org/lookup/doi/10.1042/BST0370727
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http://dx.doi.org/10.1042/BST0370727DOI Listing
August 2009

Satisfaction of hydrogen-bonding potential influences the conservation of polar sidechains.

Proteins 2009 May;75(2):413-29

Biochemistry Department, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1002/prot.22248DOI Listing
May 2009

AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity.

J Biol Chem 2008 Jan 1;283(3):1723-31. Epub 2007 Nov 1.

Department of Pathology, Divisions of Immunology and Cellular Pathology, University of Cambridge, Tennis Court Road, Cambridge, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M707211200DOI Listing
January 2008

Genome bioinformatic analysis of nonsynonymous SNPs.

BMC Bioinformatics 2007 Aug 20;8:301. Epub 2007 Aug 20.

Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK.

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http://dx.doi.org/10.1186/1471-2105-8-301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1978506PMC
August 2007

PDBLIG: classification of small molecular protein binding in the Protein Data Bank.

J Med Chem 2004 Jul;47(15):3807-16

Department of Molecular Design, Inpharmatica, 60 Charlotte Street, London W1T 2NU, U.K.

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http://dx.doi.org/10.1021/jm040804fDOI Listing
July 2004