Publications by authors named "Catherine B Lawrence"

48Publications

Zinc status alters Alzheimer's disease progression through NLRP3-dependent inflammation.

Authors:
Jack Rivers-Auty Victor S Tapia Claire S White Michael Jd Daniels Samuel Drinkall Paul T Kennedy Harry G Spence Shi Yu Jack P Green Christopher Hoyle James Cook Amy Bradley Alison E Mather Ruth Peters Te-Chen Tzeng Margaret J Gordon John H Beattie David Brough Catherine B Lawrence

J Neurosci 2021 Feb 16. Epub 2021 Feb 16.

Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, U.K.

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February 2021

Anti-inflammatories in Alzheimer's disease-potential therapy or spurious correlate?

Authors:
Jack Rivers-Auty Alison E Mather Ruth Peters Catherine B Lawrence David Brough

Brain Commun 2020 24;2(2):fcaa109. Epub 2020 Jul 24.

Division of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, School of Biological Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PT, UK.

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July 2020

Inhibition of the NLRP3 inflammasome by HSP90 inhibitors.

Authors:
Sohaib Nizami Kanisa Arunasalam Jack Green James Cook Catherine B Lawrence Tryfon Zarganes-Tzitzikas John B Davis Elena Di Daniel David Brough

Immunology 2021 Jan 30;162(1):84-91. Epub 2020 Oct 30.

Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.

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January 2021

Author Correction: Proteolysis of the low density lipoprotein receptor by bone morphogenetic protein-1 regulates cellular cholesterol uptake.

Authors:
Sreemoti Banerjee Robert J Andrew Christopher J Duff Kate Fisher Carolyn D Jackson Catherine B Lawrence Nobuyo Maeda Daniel S Greenspan Katherine A B Kellett Nigel M Hooper

Sci Rep 2020 Feb 11;10(1):2681. Epub 2020 Feb 11.

School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Sciences, Manchester, M13 9PT, UK.

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February 2020

Stroke Induces Prolonged Changes in Lipid Metabolism, the Liver and Body Composition in Mice.

Authors:
Michael J Haley Claire S White Daisy Roberts Kelly O'Toole Catriona J Cunningham Jack Rivers-Auty Conor O'Boyle Conor Lane Oliver Heaney Stuart M Allan Catherine B Lawrence

Transl Stroke Res 2020 08 21;11(4):837-850. Epub 2019 Dec 21.

Division of Neuroscience and Experimental Psychology and Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, M13 9PT, UK.

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August 2020

Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation.

Authors:
Channabasavaiah B Gurumurthy Aidan R O'Brien Rolen M Quadros John Adams Pilar Alcaide Shinya Ayabe Johnathan Ballard Surinder K Batra Marie-Claude Beauchamp Kathleen A Becker Guillaume Bernas David Brough Francisco Carrillo-Salinas Wesley Chan Hanying Chen Ruby Dawson Victoria DeMambro Jinke D'Hont Katharine M Dibb James D Eudy Lin Gan Jing Gao Amy Gonzales Anyonya R Guntur Huiping Guo Donald W Harms Anne Harrington Kathryn E Hentges Neil Humphreys Shiho Imai Hideshi Ishii Mizuho Iwama Eric Jonasch Michelle Karolak Bernard Keavney Nay-Chi Khin Masamitsu Konno Yuko Kotani Yayoi Kunihiro Imayavaramban Lakshmanan Catherine Larochelle Catherine B Lawrence Lin Li Volkhard Lindner Xian-De Liu Gloria Lopez-Castejon Andrew Loudon Jenna Lowe Loydie A Jerome-Majewska Taiji Matsusaka Hiromi Miura Yoshiki Miyasaka Benjamin Morpurgo Katherine Motyl Yo-Ichi Nabeshima Koji Nakade Toshiaki Nakashiba Kenichi Nakashima Yuichi Obata Sanae Ogiwara Mariette Ouellet Leif Oxburgh Sandra Piltz Ilka Pinz Moorthy P Ponnusamy David Ray Ronald J Redder Clifford J Rosen Nikki Ross Mark T Ruhe Larisa Ryzhova Ane M Salvador Sabrina Shameen Alam Radislav Sedlacek Karan Sharma Chad Smith Katrien Staes Lora Starrs Fumihiro Sugiyama Satoru Takahashi Tomohiro Tanaka Andrew W Trafford Yoshihiro Uno Leen Vanhoutte Frederique Vanrockeghem Brandon J Willis Christian S Wright Yuko Yamauchi Xin Yi Kazuto Yoshimi Xuesong Zhang Yu Zhang Masato Ohtsuka Satyabrata Das Daniel J Garry Tino Hochepied Paul Thomas Jan Parker-Thornburg Antony D Adamson Atsushi Yoshiki Jean-Francois Schmouth Andrei Golovko William R Thompson K C Kent Lloyd Joshua A Wood Mitra Cowan Tomoji Mashimo Seiya Mizuno Hao Zhu Petr Kasparek Lucy Liaw Joseph M Miano Gaetan Burgio

Genome Biol 2019 08 26;20(1):171. Epub 2019 Aug 26.

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, the Australian National University, Canberra, Australia.

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August 2019

Proteolysis of the low density lipoprotein receptor by bone morphogenetic protein-1 regulates cellular cholesterol uptake.

Authors:
Sreemoti Banerjee Robert J Andrew Christopher J Duff Kate Fisher Carolyn D Jackson Catherine B Lawrence Nobuyo Maeda Daniel S Greenspan Katherine A B Kellett Nigel M Hooper

Sci Rep 2019 08 6;9(1):11416. Epub 2019 Aug 6.

School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Sciences, Manchester, M13 9PT, UK.

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August 2019

Old Dog New Tricks; Revisiting How Stroke Modulates the Systemic Immune Landscape.

Authors:
Siddharth Krishnan Catherine B Lawrence

Front Neurol 2019 2;10:718. Epub 2019 Jul 2.

Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, United Kingdom.

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July 2019

Ligature-induced periodontitis induces systemic inflammation but does not alter acute outcome after stroke in mice.

Authors:
Conor O'Boyle Michael J Haley Eloise Lemarchand Craig J Smith Stuart M Allan Joanne E Konkel Catherine B Lawrence

Int J Stroke 2020 02 22;15(2):175-187. Epub 2019 Feb 22.

Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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February 2020

Chloride regulates dynamic NLRP3-dependent ASC oligomerization and inflammasome priming.

Authors:
Jack P Green Shi Yu Fátima Martín-Sánchez Pablo Pelegrin Gloria Lopez-Castejon Catherine B Lawrence David Brough

Proc Natl Acad Sci U S A 2018 10 19;115(40):E9371-E9380. Epub 2018 Sep 19.

Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, M13 9PT Manchester, United Kingdom;

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October 2018

Is Targeting the Inflammasome a Way Forward for Neuroscience Drug Discovery?

Authors:
Tessa Swanton James Cook James A Beswick Sally Freeman Catherine B Lawrence David Brough

SLAS Discov 2018 12 3;23(10):991-1017. Epub 2018 Jul 3.

1 Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.

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December 2018

Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology.

Authors:
Karen Horsburgh Joanna M Wardlaw Tom van Agtmael Stuart M Allan Mike L J Ashford Philip M Bath Rosalind Brown Jason Berwick M Zameel Cader Roxana O Carare John B Davis Jessica Duncombe Tracy D Farr Jill H Fowler Jozien Goense Alessandra Granata Catherine N Hall Atticus H Hainsworth Adam Harvey Cheryl A Hawkes Anne Joutel Rajesh N Kalaria Patrick G Kehoe Catherine B Lawrence Andy Lockhart Seth Love Malcolm R Macleod I Mhairi Macrae Hugh S Markus Chris McCabe Barry W McColl Paul J Meakin Alyson Miller Maiken Nedergaard Michael O'Sullivan Terry J Quinn Rikesh Rajani Lisa M Saksida Colin Smith Kenneth J Smith Rhian M Touyz Rebecca C Trueman Tao Wang Anna Williams Steven C R Williams Lorraine M Work

Clin Sci (Lond) 2018 04 30;132(8):851-868. Epub 2018 Apr 30.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, U.K.

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April 2018

Acute high-fat feeding leads to disruptions in glucose homeostasis and worsens stroke outcome.

Authors:
Michael J Haley Siddharth Krishnan David Burrows Leon de Hoog Jamie Thakrar Ingo Schiessl Stuart M Allan Catherine B Lawrence

J Cereb Blood Flow Metab 2019 06 24;39(6):1026-1037. Epub 2017 Nov 24.

Faculty of Biology, Medicine and Health, The University of Manchester, Oxford Road, Manchester, UK.

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June 2019

Boron-Based Inhibitors of the NLRP3 Inflammasome.

Authors:
Alex G Baldwin Jack Rivers-Auty Michael J D Daniels Claire S White Carl H Schwalbe Tom Schilling Halah Hammadi Panichakorn Jaiyong Nicholas G Spencer Hazel England Nadia M Luheshi Manikandan Kadirvel Catherine B Lawrence Nancy J Rothwell Michael K Harte Richard A Bryce Stuart M Allan Claudia Eder Sally Freeman David Brough

Cell Chem Biol 2017 Nov 21;24(11):1321-1335.e5. Epub 2017 Sep 21.

Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, UK. Electronic address:

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November 2017

Adipose tissue and metabolic and inflammatory responses to stroke are altered in obese mice.

Authors:
Michael J Haley Graham Mullard Katherine A Hollywood Garth J Cooper Warwick B Dunn Catherine B Lawrence

Dis Model Mech 2017 10 10;10(10):1229-1243. Epub 2017 Aug 10.

Faculty of Biological, Medical and Human Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, M13 9PT, UK

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October 2017

Eosinophils are key regulators of perivascular adipose tissue and vascular functionality.

Authors:
Sarah B Withers Ruth Forman Selene Meza-Perez Daniel Sorobetea Kasia Sitnik Thomas Hopwood Catherine B Lawrence William W Agace Kathryn J Else Anthony M Heagerty Marcus Svensson-Frej Sheena M Cruickshank

Sci Rep 2017 03 17;7:44571. Epub 2017 Mar 17.

Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

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March 2017

Inflammasomes as therapeutic targets for Alzheimer's disease.

Authors:
Claire S White Catherine B Lawrence David Brough Jack Rivers-Auty

Brain Pathol 2017 03;27(2):223-234

Faculty of Biology, Medicine and Health, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK.

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March 2017

Mitochondrial Abnormalities and Synaptic Loss Underlie Memory Deficits Seen in Mouse Models of Obesity and Alzheimer's Disease.

Authors:
Isaura V A Martins Jack Rivers-Auty Stuart M Allan Catherine B Lawrence

J Alzheimers Dis 2017 ;55(3):915-932

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February 2018

Elevated Hypothalamic Glucocorticoid Levels Are Associated With Obesity and Hyperphagia in Male Mice.

Authors:
Charlotte Sefton Erika Harno Alison Davies Helen Small Tiffany-Jayne Allen Jonathan R Wray Catherine B Lawrence Anthony P Coll Anne White

Endocrinology 2016 Nov 20;157(11):4257-4265. Epub 2016 Sep 20.

Faculty of Biology (C.S., E.H., A.D., T.-J.A., J.R.W., C.B.L., A.W.), Medicine and Health, University of Manchester, Manchester M13 9PT, United Kingdom; Cancer Research UK Manchester Institute (H.S.), University of Manchester, Manchester M20 4BX, United Kingdom; and University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit (A.P.C.), Wellcome-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 0QQ, United Kingdom.

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November 2016

Obesity and stroke: Can we translate from rodents to patients?

Authors:
Michael J Haley Catherine B Lawrence

J Cereb Blood Flow Metab 2016 12 21;36(12):2007-2021. Epub 2016 Sep 21.

Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK

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December 2016