Catharina Svanborg

Catharina Svanborg

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Catharina Svanborg

Publications by authors named "Catharina Svanborg"

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Beta-sheet-specific interactions with heat shock proteins define a mechanism of delayed tumor cell death in response to HAMLET.

J Mol Biol 2019 Jun 11;431(14):2612-2627. Epub 2019 May 11.

Department of Microbiology, Immunology and Glycobiology (MIG), Institute of Laboratory Medicine, Lund University, S-223 62 Lund, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00222836193026
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http://dx.doi.org/10.1016/j.jmb.2019.05.007DOI Listing
June 2019

Fimbriae reprogram host gene expression - Divergent effects of P and type 1 fimbriae.

PLoS Pathog 2019 06 10;15(6):e1007671. Epub 2019 Jun 10.

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Klinikgatan, Lund, Sweden.

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http://dx.doi.org/10.1371/journal.ppat.1007671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557620PMC
June 2019

Neuroepithelial control of mucosal inflammation in acute cystitis.

Sci Rep 2018 07 20;8(1):11015. Epub 2018 Jul 20.

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, 223 62, Lund, Sweden.

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http://dx.doi.org/10.1038/s41598-018-28634-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054610PMC
July 2018

HAMLET - A protein-lipid complex with broad tumoricidal activity.

Biochem Biophys Res Commun 2017 01 3;482(3):454-458. Epub 2017 Feb 3.

Department of Microbiology, Immunology and Glycobiology (MIG), Institute of Laboratory Medicine, Lund University, S-223 62 Lund, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.10.092DOI Listing
January 2017

Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets.

PLoS Pathog 2016 10 12;12(10):e1005848. Epub 2016 Oct 12.

Division of Microbiology, Immunology and Glycobiology, Department of Laboratory Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1371/journal.ppat.1005848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061333PMC
October 2016

Bacterial Suppression of RNA Polymerase II-Dependent Host Gene Expression.

Pathogens 2016 Jul 13;5(3). Epub 2016 Jul 13.

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, 22184 Lund, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039429PMC
http://dx.doi.org/10.3390/pathogens5030049DOI Listing
July 2016

Deliberate Establishment of Asymptomatic Bacteriuria-A Novel Strategy to Prevent Recurrent UTI.

Pathogens 2016 Jul 29;5(3). Epub 2016 Jul 29.

Department of Microbiology, Immunology and Glycobiology (MIG), Institute of Laboratory Medicine, Lund University, 221 00 Lund, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039432PMC
http://dx.doi.org/10.3390/pathogens5030052DOI Listing
July 2016

Susceptibility to Urinary Tract Infection: Benefits and Hazards of the Antibacterial Host Response.

Microbiol Spectr 2016 06;4(3)

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, S-223 62, Sweden.

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http://dx.doi.org/10.1128/microbiolspec.UTI-0019-2014DOI Listing
June 2016

IRF7 inhibition prevents destructive innate immunity-A target for nonantibiotic therapy of bacterial infections.

Sci Transl Med 2016 04;8(336):336ra59

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, 223 62 Lund, Sweden.

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http://dx.doi.org/10.1126/scitranslmed.aaf1156DOI Listing
April 2016

Asymtomatic Bacteriuria as a Model to Study the Coevolution of Hosts and Bacteria.

Pathogens 2016 Feb 15;5(1). Epub 2016 Feb 15.

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Sölvegatan 23, S-223 62 Lund, Sweden.

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http://dx.doi.org/10.3390/pathogens5010021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810142PMC
February 2016

Urinary Tract Infection Molecular Mechanisms and Clinical Translation.

Pathogens 2016 Feb 24;5(1). Epub 2016 Feb 24.

Department of Microbiology, Immunology and Glycobiology (MIG), Institute of Laboratory Medicine, Lund University, 221 00 Lund, Sweden.

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http://dx.doi.org/10.3390/pathogens5010024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810145PMC
February 2016

A Comparative Analysis of the Mechanism of Toll-Like Receptor-Disruption by TIR-Containing Protein C from Uropathogenic Escherichia coli.

Pathogens 2016 Feb 29;5(1). Epub 2016 Feb 29.

Institute of Medical Microbiology and Hygiene, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany.

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http://dx.doi.org/10.3390/pathogens5010025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810146PMC
February 2016

Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex.

Sci Rep 2015 Nov 12;5:16432. Epub 2015 Nov 12.

Department of Microbiology, Immunology and Glycobiology (MIG), Institute of Laboratory Medicine, Lund University, S-223 62 Lund, Sweden.

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http://dx.doi.org/10.1038/srep16432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642337PMC
November 2015

The molecular motor F-ATP synthase is targeted by the tumoricidal protein HAMLET.

J Mol Biol 2015 May 11;427(10):1866-74. Epub 2015 Feb 11.

School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Republic of Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2015.01.024DOI Listing
May 2015

Innate immunity and genetic determinants of urinary tract infection susceptibility.

Curr Opin Infect Dis 2015 Feb;28(1):88-96

Department of Microbiology, Immunology and Glycobiology, Institute for Laboratory Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1097/QCO.0000000000000127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286230PMC
February 2015

Polyethyleneimine is a potent systemic adjuvant for glycoprotein antigens.

Int Immunol 2014 Oct 20;26(10):531-8. Epub 2014 May 20.

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX13RE, UK Present address: Crucell Holland B.V., Archimedesweg 4-6, 2333CN Leiden, The Netherlands

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http://dx.doi.org/10.1093/intimm/dxu055DOI Listing
October 2014

The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infection.

Immunity 2014 Apr;40(4):621-32

Humanitas Clinical Research Center, via Manzoni 56, 20089 Rozzano (Milano), Italy; Department of Biotechnology and Translational Medicine, University of Milan, 20089 Rozzano (Milano), Italy. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.02.015DOI Listing
April 2014

Rare emergence of symptoms during long-term asymptomatic Escherichia coli 83972 carriage without an altered virulence factor repertoire.

J Urol 2014 Feb 30;191(2):519-28. Epub 2013 Jul 30.

Institute for Molecular Biology of Infectious Diseases, University of Würzburg, Würzburg, Germany; Institute for Hygiene, University of Münster, Münster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2013.07.060DOI Listing
February 2014

Prevention and treatment of colon cancer by peroral administration of HAMLET (human α-lactalbumin made lethal to tumour cells).

Gut 2014 Jan 24;63(1):131-42. Epub 2013 Jan 24.

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, , Lund, Sweden.

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http://dx.doi.org/10.1136/gutjnl-2012-303715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888589PMC
January 2014

Preface. Between Pathogenicity and Commensalism.

Curr Top Microbiol Immunol 2013 ;358:v-vii

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http://dx.doi.org/10.1007/978-3-642-36560-7DOI Listing
July 2013

Lipids as tumoricidal components of human α-lactalbumin made lethal to tumor cells (HAMLET): unique and shared effects on signaling and death.

J Biol Chem 2013 Jun 29;288(24):17460-71. Epub 2013 Apr 29.

Department of Microbiology, Immunology, and Glycobiology (MIG), Institute of Laboratory Medicine, Lund University, Sölvegatan 23, S-223 62 Lund, Sweden.

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http://dx.doi.org/10.1074/jbc.M113.468405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682546PMC
June 2013

Urinary tract infections in children: microbial virulence versus host susceptibility.

Adv Exp Med Biol 2013 ;764:205-10

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1007/978-1-4614-4726-9_17DOI Listing
June 2013

Bacterial control of host gene expression through RNA polymerase II.

J Clin Invest 2013 Jun;123(6):2366-79

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1172/JCI66451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668848PMC
June 2013

Electrostatic interactions play an essential role in the binding of oleic acid with α-lactalbumin in the HAMLET-like complex: a study using charge-specific chemical modifications.

Proteins 2013 Jan 29;81(1):1-17. Epub 2012 Sep 29.

Trinity Biomedical Sciences Institute-TBSI, School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland.

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http://doi.wiley.com/10.1002/prot.24141
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http://dx.doi.org/10.1002/prot.24141DOI Listing
January 2013

Susceptibility to acute pyelonephritis or asymptomatic bacteriuria: host-pathogen interaction in urinary tract infections.

Pediatr Nephrol 2012 Nov 12;27(11):2017-2029. Epub 2012 Feb 12.

Institute of Laboratory Medicine, Section of Microbiology, Immunology and Glycobiology (MIG), Lund University, Sölvegatan 23, 22362, Lund, Sweden.

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http://dx.doi.org/10.1007/s00467-011-2089-1DOI Listing
November 2012

HAMLET: functional properties and therapeutic potential.

Future Oncol 2012 Oct;8(10):1301-13

Department of Microbiology, Immunology & Glycobiology (MIG), Institute of Laboratory Medicine, Lund University, Sölvegatan 23, S-223 62 Lund, Sweden.

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http://dx.doi.org/10.2217/fon.12.122DOI Listing
October 2012

Alternatively folded proteins with unexpected beneficial functions.

Biochem Soc Trans 2012 Aug;40(4):746-51

Trinity Biomedical Sciences Institute, School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland.

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http://www.biochemsoctrans.org/content/ppbiost/40/4/746.full
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http://biochemsoctrans.org/lookup/doi/10.1042/BST20120029
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http://dx.doi.org/10.1042/BST20120029DOI Listing
August 2012

Genetic control of the variable innate immune response to asymptomatic bacteriuria.

PLoS One 2011 28;6(11):e28289. Epub 2011 Nov 28.

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0028289PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225390PMC
April 2012

HAMLET forms annular oligomers when deposited with phospholipid monolayers.

J Mol Biol 2012 Apr 16;418(1-2):90-102. Epub 2012 Feb 16.

Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009 Bergen, Norway.

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http://dx.doi.org/10.1016/j.jmb.2012.02.006DOI Listing
April 2012

Do Escherichia coli strains causing acute cystitis have a distinct virulence repertoire?

Microb Pathog 2012 Jan 18;52(1):10-6. Epub 2011 Oct 18.

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Sölvegatan 23, SE-22362 Lund, Sweden.

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http://dx.doi.org/10.1016/j.micpath.2011.08.005DOI Listing
January 2012

Acute pyelonephritis and renal scarring are caused by dysfunctional innate immunity in mCxcr2 heterozygous mice.

Kidney Int 2011 Nov 3;80(10):1064-72. Epub 2011 Aug 3.

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1038/ki.2011.257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257042PMC
November 2011

Genetics of innate immunity and UTI susceptibility.

Nat Rev Urol 2011 Jul 12;8(8):449-68. Epub 2011 Jul 12.

Section of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Sölvegatan 23, 22362 Lund, Sweden.

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http://dx.doi.org/10.1038/nrurol.2011.100DOI Listing
July 2011

HAMLET binding to α-actinin facilitates tumor cell detachment.

PLoS One 2011 Mar 8;6(3):e17179. Epub 2011 Mar 8.

Institute of Laboratory Medicine, Department of Microbiology, Immunology and Glycobiology, Lund University, Lund, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017179PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050841PMC
March 2011

Apoptosis-like death in bacteria induced by HAMLET, a human milk lipid-protein complex.

PLoS One 2011 Mar 10;6(3):e17717. Epub 2011 Mar 10.

Department of Microbiology and Immunology, University at Buffalo, State University of New York, Buffalo, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017717PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053380PMC
March 2011

Structure and function of human α-lactalbumin made lethal to tumor cells (HAMLET)-type complexes.

FEBS J 2010 Nov;277(22):4614-25

Department of Microbiology, Immunology and Glycobiology (MIG), Institute of Laboratory Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1111/j.1742-4658.2010.07890.xDOI Listing
November 2010

HAMLET treatment delays bladder cancer development.

J Urol 2010 Apr 21;183(4):1590-7. Epub 2010 Feb 21.

Department of Microbiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1016/j.juro.2009.12.008DOI Listing
April 2010

HAMLET interacts with lipid membranes and perturbs their structure and integrity.

PLoS One 2010 Feb 23;5(2):e9384. Epub 2010 Feb 23.

Section of Microbiology, Immunology, and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009384PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826418PMC
February 2010

alpha-Lactalbumin, engineered to be nonnative and inactive, kills tumor cells when in complex with oleic acid: a new biological function resulting from partial unfolding.

J Mol Biol 2009 Dec 18;394(5):994-1010. Epub 2009 Sep 18.

Department of Microbiology, Immunology and Glycobiology (MIG), Institute of Laboratory Medicine, Faculty of Medicine, Lund University, 223 62 Lund, Sweden.

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http://dx.doi.org/10.1016/j.jmb.2009.09.026DOI Listing
December 2009

Changes in proteasome structure and function caused by HAMLET in tumor cells.

PLoS One 2009 14;4(4):e5229. Epub 2009 Apr 14.

Department of Microbiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005229PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664966PMC
October 2009

Can misfolded proteins be beneficial? The HAMLET case.

Ann Med 2009 ;41(3):162-76

Department of Microbiology, Immunology and Glycobiology (MIG), Institute of Laboratory Medicine, Lund University, Sölvegatan 23, Lund, Sweden.

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http://dx.doi.org/10.1080/07853890802502614DOI Listing
July 2009

Therapeutic effect of blocking CXCR2 on neutrophil recruitment and dextran sodium sulfate-induced colitis.

J Pharmacol Exp Ther 2009 Apr 8;329(1):123-9. Epub 2009 Jan 8.

Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada.

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http://dx.doi.org/10.1124/jpet.108.145862DOI Listing
April 2009

HAMLET (human alpha-lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death.

Int J Cancer 2009 Mar;124(5):1008-19

Institute of Laboratory Medicine, Section of Microbiology, Immunology and Glycobiology, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1002/ijc.24076DOI Listing
March 2009

Virulence properties of asymptomatic bacteriuria Escherichia coli.

Int J Med Microbiol 2009 Jan 15;299(1):53-63. Epub 2008 Aug 15.

School of Molecular and Microbial Sciences, University of Queensland, Brisbane, QLD, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S143842210800079
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http://dx.doi.org/10.1016/j.ijmm.2008.06.003DOI Listing
January 2009

Shiga toxin-mediated disease in MyD88-deficient mice infected with Escherichia coli O157:H7.

Am J Pathol 2008 Nov 2;173(5):1428-39. Epub 2008 Oct 2.

Department of Pediatrics, Clinical Sciences Lund, Lund University, 22185 Lund.

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http://dx.doi.org/10.2353/ajpath.2008.071218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570133PMC
November 2008

Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain-containing proteins.

Nat Med 2008 Apr 9;14(4):399-406. Epub 2008 Mar 9.

Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, Trogerstrasse 30, D-81675 München, Germany.

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https://www.nature.com/articles/nm1734.pdf
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http://www.nature.com/articles/nm1734
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http://dx.doi.org/10.1038/nm1734DOI Listing
April 2008

Molecular basis of commensalism in the urinary tract: low virulence or virulence attenuation?

Infect Immun 2008 Feb 26;76(2):695-703. Epub 2007 Nov 26.

Institut für Molekulare Infektionsbiologie, Julius-Maximilians-Universität Würzburg, Röntgenring 11, 97070 Würzburg, Germany.

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http://dx.doi.org/10.1128/IAI.01215-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223460PMC
February 2008

Histone deacetylase inhibitors promote the tumoricidal effect of HAMLET.

Cancer Res 2007 Dec;67(23):11327-34

Institute of Laboratory Medicine, Section of Microbiology, Immunology, and Glycobiology, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-1153DOI Listing
December 2007

Bladder cancers respond to intravesical instillation of HAMLET (human alpha-lactalbumin made lethal to tumor cells).

Int J Cancer 2007 Sep;121(6):1352-9

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1002/ijc.22810DOI Listing
September 2007

Reduced toll-like receptor 4 expression in children with asymptomatic bacteriuria.

J Infect Dis 2007 Aug 21;196(3):475-84. Epub 2007 Jun 21.

Department of Microbiology, Immunology, and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, 22362, Sweden.

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https://academic.oup.com/jid/article-lookup/doi/10.1086/5188
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http://dx.doi.org/10.1086/518893DOI Listing
August 2007

Do type 1 fimbriae promote inflammation in the human urinary tract?

Cell Microbiol 2007 Jul 13;9(7):1766-81. Epub 2007 Mar 13.

Department of Microbiology, Immunology, and Glycobiology, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1111/j.1462-5822.2007.00912.xDOI Listing
July 2007

Ceramide as a TLR4 agonist; a putative signalling intermediate between sphingolipid receptors for microbial ligands and TLR4.

Cell Microbiol 2007 May 11;9(5):1239-51. Epub 2007 Jan 11.

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Sölvegatan 23, S-22362 Lund, Sweden.

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http://doi.wiley.com/10.1111/j.1462-5822.2006.00867.x
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http://dx.doi.org/10.1111/j.1462-5822.2006.00867.xDOI Listing
May 2007

Inherited susceptibility to acute pyelonephritis: a family study of urinary tract infection.

J Infect Dis 2007 Apr 12;195(8):1227-34. Epub 2007 Mar 12.

Department of Microbiology, Immunology, and Glycobiology, Lund University, Lund, S-223 62, Sweden.

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http://dx.doi.org/10.1086/512620DOI Listing
April 2007

HAMLET, protein folding, and tumor cell death.

Biochem Biophys Res Commun 2007 Mar 29;354(1):1-7. Epub 2006 Dec 29.

Trinity College, School of Biochemistry and Immunology, University of Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1016/j.bbrc.2006.12.167DOI Listing
March 2007

alpha-Lactalbumin species variation, HAMLET formation, and tumor cell death.

Biochem Biophys Res Commun 2006 Jun 27;345(1):260-70. Epub 2006 Apr 27.

Department of Microbiology, Immunology and Glycobiology (MIG), Institute of Laboratory Medicine, Lund University, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2006.04.081DOI Listing
June 2006

Glycolipid receptor depletion as an approach to specific antimicrobial therapy.

FEMS Microbiol Lett 2006 May;258(1):1-8

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, University of Lund, Lund, Sweden.

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http://dx.doi.org/10.1111/j.1574-6968.2006.00175.xDOI Listing
May 2006

Mechanism of pathogen-specific TLR4 activation in the mucosa: fimbriae, recognition receptors and adaptor protein selection.

Eur J Immunol 2006 Feb;36(2):267-77

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, S-22362 Lund, Sweden.

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http://dx.doi.org/10.1002/eji.200535149DOI Listing
February 2006

Uropathogenic Escherichia coli as a model of host-parasite interaction.

Curr Opin Microbiol 2006 Feb 6;9(1):33-9. Epub 2006 Jan 6.

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S136952740500206
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http://dx.doi.org/10.1016/j.mib.2005.12.012DOI Listing
February 2006

Molecular characterization of the Escherichia coli asymptomatic bacteriuria strain 83972: the taming of a pathogen.

Infect Immun 2006 Jan;74(1):781-5

School of Molecular and Microbial Sciences, Building 76, University of Queensland, Brisbane QLD 4072, Australia.

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http://iai.asm.org/cgi/doi/10.1128/IAI.74.1.781-785.2006
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http://dx.doi.org/10.1128/IAI.74.1.781-785.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1346676PMC
January 2006

Compact oleic acid in HAMLET.

FEBS Lett 2005 Nov 6;579(27):6095-100. Epub 2005 Oct 6.

Department of Biophysical Chemistry, Lund University, P.O. Box 124, SE-221 00 Lund, Sweden.

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http://dx.doi.org/10.1016/j.febslet.2005.08.089DOI Listing
November 2005

Escherichia coli, fimbriae, bacterial persistence and host response induction in the human urinary tract.

Int J Med Microbiol 2005 Oct;295(6-7):487-502

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S143842210500102
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http://dx.doi.org/10.1016/j.ijmm.2005.07.008DOI Listing
October 2005

HAMLET kills tumor cells by apoptosis: structure, cellular mechanisms, and therapy.

J Nutr 2005 May;135(5):1299-303

Institute of Laboratory Medicine, Department of Microbiology, Immunology and Glycobiology, Lund University, Sweden.

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http://dx.doi.org/10.1093/jn/135.5.1299DOI Listing
May 2005

Stability of HAMLET--a kinetically trapped alpha-lactalbumin oleic acid complex.

Protein Sci 2005 Feb;14(2):329-40

Department of Chemistry and Biochemistry, University of Colorado, Cristol Building, Room 226, Boulder, CO 80309-0215, USA.

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http://dx.doi.org/10.1110/ps.04982905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253409PMC
February 2005

Natural history of renal scarring in susceptible mIL-8Rh-/- mice.

Kidney Int 2005 Jan;67(1):103-10

Institute of Laboratory Medicine, Department of Microbiology, Immunology and Glycobiology, University of Lund, Lund, Sweden.

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http://dx.doi.org/10.1111/j.1523-1755.2005.00060.xDOI Listing
January 2005

Toll-like receptor 4 expression and cytokine responses in the human urinary tract mucosa.

Infect Immun 2004 Jun;72(6):3179-86

Department of Laboratory Medicine, Division of Microbiology, Immunology and Glycobiology, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1128/IAI.72.6.3179-3186.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC415697PMC
June 2004

Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid.

N Engl J Med 2004 Jun;350(26):2663-72

Institute of Laboratory Medicine, Department of Microbiology, Immunology, and Glycobiology, University of Lund, Lund, Sweden.

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http://dx.doi.org/10.1056/NEJMoa032454DOI Listing
June 2004

Conformational analysis of HAMLET, the folding variant of human alpha-lactalbumin associated with apoptosis.

Protein Sci 2004 May 9;13(5):1322-30. Epub 2004 Apr 9.

Dipartimento di Chimica Organica e Biochimica, Università di Napoli Federico II, I-80126 Napoli, Italy.

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http://doi.wiley.com/10.1110/ps.03474704
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http://dx.doi.org/10.1110/ps.03474704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2286754PMC
May 2004

PapG-dependent adherence breaks mucosal inertia and triggers the innate host response.

J Infect Dis 2004 May 14;189(9):1734-42. Epub 2004 Apr 14.

Department of Microbiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1086/383278DOI Listing
May 2004

Human alpha-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival.

Cancer Res 2004 Mar;64(6):2105-12

Institute of Laboratory Medicine, Department of Microbiology, Immunology and Glycobiology, University of Lund, Sölvegatan 23, 223-62 Lund, Sweden.

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http://dx.doi.org/10.1158/0008-5472.can-03-2661DOI Listing
March 2004

HAMLET interacts with histones and chromatin in tumor cell nuclei.

J Biol Chem 2003 Oct 29;278(43):42131-5. Epub 2003 Jul 29.

Institute of Laboratory Medicine, Section for Microbiology, Immunology and Glycobiology, Lund University, Sölvegatan 23, 223 62 Lund, Sweden.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M306462200
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October 2003

Hamlet--a complex from human milk that induces apoptosis in tumor cells but spares healthy cells.

Adv Exp Med Biol 2002 ;503:125-32

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Sweden.

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http://dx.doi.org/10.1007/978-1-4615-0559-4_14DOI Listing
January 2003

Glycolipid depletion in antimicrobial therapy.

Mol Microbiol 2003 Jan;47(2):453-61

Department of Laboratory Medicine, Division of Microbiology, Lund University, S-223 62 Lund, Sweden.

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http://dx.doi.org/10.1046/j.1365-2958.2003.03306.xDOI Listing
January 2003

The role of P fimbriae for Escherichia coli establishment and mucosal inflammation in the human urinary tract.

Int J Antimicrob Agents 2002 Jun;19(6):522-38

Division of Clinical Immunology, Department of Laboratory Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1016/s0924-8579(02)00103-6DOI Listing
June 2002

Human renal epithelial cells express iNOS in response to cytokines but not bacteria.

Kidney Int 2002 Feb;61(2):444-55

Department of Clinical Pharmacology, Lund University Hospital, Lund, Sweden.

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http://dx.doi.org/10.1046/j.1523-1755.2002.00138.xDOI Listing
February 2002