Caterina Nardella

Caterina Nardella

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Caterina Nardella

Caterina Nardella

Publications by authors named "Caterina Nardella"

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28Publications

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Allosteric feedback inhibition of pyridoxine 5'-phosphate oxidase from .

J Biol Chem 2019 Oct 4;294(43):15593-15603. Epub 2019 Sep 4.

Dipartimento di Scienze Biochimiche "A. Rossi Fanelli," Sapienza Università di Roma, Laboratory affiliated with Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Piazzale Aldo Moro 5, 00185 Roma, Italy

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http://dx.doi.org/10.1074/jbc.RA119.009697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816108PMC
October 2019

Isolation of a Complex Formed Between HemA and HemL, Key Enzymes of Tetrapyrroles Biosynthesis.

Front Mol Biosci 2019 26;6. Epub 2019 Feb 26.

Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Dipartimento di Scienze Biochimiche "A. Rossi Fanelli", Sapienza Università di Roma, Rome, Italy.

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https://www.frontiersin.org/article/10.3389/fmolb.2019.00006
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http://dx.doi.org/10.3389/fmolb.2019.00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399207PMC
February 2019

Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties.

Biochemistry 2018 12 7;57(51):6984-6996. Epub 2018 Dec 7.

Dipartimento di Scienze Biochimiche "A. Rossi Fanelli" , Sapienza Università di Roma, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti , Piazzale Aldo Moro 5 , 00185 Roma , Italy.

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http://dx.doi.org/10.1021/acs.biochem.8b01074DOI Listing
December 2018

The MocR-like transcription factors: pyridoxal 5'-phosphate-dependent regulators of bacterial metabolism.

FEBS J 2018 11 5;285(21):3925-3944. Epub 2018 Jul 5.

Dipartimento di Scienze Biochimiche "A. Rossi Fanelli", Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza Università di Roma, Italy.

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http://dx.doi.org/10.1111/febs.14599DOI Listing
November 2018

Editorial: Precision Medicine in Oncology.

Front Oncol 2018 26;8:479. Epub 2018 Oct 26.

Armenise-Harvard Cancer Biology & Genetics Laboratory, Centre for Integrative Biology, Trento, Italy.

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http://dx.doi.org/10.3389/fonc.2018.00479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212552PMC
October 2018

Salmonella typhimurium PtsJ is a novel MocR-like transcriptional repressor involved in regulating the vitamin B salvage pathway.

FEBS J 2017 02 9;284(3):466-484. Epub 2017 Jan 9.

Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Italy.

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http://dx.doi.org/10.1111/febs.13994DOI Listing
February 2017

Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition.

Cancer Discov 2014 Aug 27;4(8):896-904. Epub 2014 May 27.

Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School; Department of Medicine; Divisions of

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http://dx.doi.org/10.1158/2159-8290.CD-13-0230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125493PMC
August 2014

Of model pets and cancer models: an introduction to mouse models of cancer.

Cold Spring Harb Protoc 2014 Jan 1;2014(1):17-31. Epub 2014 Jan 1.

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

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http://www.cshprotocols.org/lookup/doi/10.1101/pdb.top069757
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http://dx.doi.org/10.1101/pdb.top069757DOI Listing
January 2014

Translation-dependent mechanisms lead to PML upregulation and mediate oncogenic K-RAS-induced cellular senescence.

EMBO Mol Med 2012 Jul 21;4(7):594-602. Epub 2012 Mar 21.

Cancer Biology and Genetics Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1002/emmm.201200233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407947PMC
July 2012

The APL paradigm and the "co-clinical trial" project.

Cancer Discov 2011 Jul;1(2):108-16

Cancer Genetics Program, Division of Genetics, Department of Medicine and Pathology, Beth Israel Deaconess Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-11-0061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222327PMC
July 2011

Pro-senescence therapy for cancer treatment.

Nat Rev Cancer 2011 Jun 24;11(7):503-11. Epub 2011 Jun 24.

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA 02215, USA.

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http://dx.doi.org/10.1038/nrc3057DOI Listing
June 2011

Differential expression of S6K2 dictates tissue-specific requirement for S6K1 in mediating aberrant mTORC1 signaling and tumorigenesis.

Cancer Res 2011 May 28;71(10):3669-75. Epub 2011 Mar 28.

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-3962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096749PMC
May 2011

Faithfull modeling of PTEN loss driven diseases in the mouse.

Curr Top Microbiol Immunol 2010 ;347:135-68

Department of Medicine and Pathology, Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1007/82_2010_62DOI Listing
January 2011

Subtle variations in Pten dose determine cancer susceptibility.

Nat Genet 2010 May 18;42(5):454-8. Epub 2010 Apr 18.

Cancer Genetics Program, Department of Medicine, Beth Israel Deaconess Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

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http://www.nature.com/articles/ng.556
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http://dx.doi.org/10.1038/ng.556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118559PMC
May 2010

A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.

J Clin Invest 2010 Mar 8;120(3):681-93. Epub 2010 Feb 8.

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Departments of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1172/JCI40535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827955PMC
March 2010

Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.

Nature 2010 Mar;464(7287):374-9

Cancer Biology and Genetics Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nature08815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928066PMC
March 2010

ETS rearrangements and prostate cancer initiation.

Nature 2009 Feb;457(7231):E1; discussion E2-3

Cancer Biology and Genetics Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nature07738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967456PMC
February 2009

Differential requirement of mTOR in postmitotic tissues and tumorigenesis.

Sci Signal 2009 Jan 27;2(55):ra2. Epub 2009 Jan 27.

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/scisignal.2000189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906144PMC
January 2009

Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events.

Genes Dev 2008 Aug;22(16):2172-7

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1101/gad.1699608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518820PMC
August 2008

Radiolabeled heparan sulfate immobilized on microplate as substrate for the detection of heparanase activity.

Anal Biochem 2004 Sep;332(2):368-75

Department of Biochemistry, IRBM/Merck Research Laboratories, Via Pontina Km 30,600, 00040, Pomezia, Italy.

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http://dx.doi.org/10.1016/j.ab.2004.05.050DOI Listing
September 2004

Mechanism of activation of human heparanase investigated by protein engineering.

Biochemistry 2004 Feb;43(7):1862-73

Department of Biochemistry, IRBM/Merck Research Laboratories, Via Pontina Km, 30600 Pomezia, Italy.

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http://dx.doi.org/10.1021/bi030203aDOI Listing
February 2004