Cate Speake

Cate Speake

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Cate Speake

Cate Speake

Publications by authors named "Cate Speake"

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Hyaluronan deposition in islets may precede and direct the location of islet immune-cell infiltrates.

Diabetologia 2020 Jan 6. Epub 2020 Jan 6.

Diabetes Research Program and Clinical Research Center, Benaroya Research Institute at Virginia Mason, Seattle, WA, USA.

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http://dx.doi.org/10.1007/s00125-019-05066-7DOI Listing
January 2020

Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis.

Diabetes 2019 Dec 11. Epub 2019 Dec 11.

Department of Pathology, Immunology, and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, Florida, USA.

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http://dx.doi.org/10.2337/db19-0942DOI Listing
December 2019

Abnormalities in proinsulin processing in islets from individuals with longstanding T1D.

Transl Res 2019 Nov 9;213:90-99. Epub 2019 Aug 9.

Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana; The Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana; Roudebush VA Medical Center, Indianapolis, Indiana. Electronic address:

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http://dx.doi.org/10.1016/j.trsl.2019.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783367PMC
November 2019

Hyaluronan levels are increased systemically in human type 2 but not type 1 diabetes independently of glycemic control.

Matrix Biol 2019 07 6;80:46-58. Epub 2018 Sep 6.

Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Beckman Center, 279 Campus Drive, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.matbio.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401354PMC
July 2019

Treg gene signatures predict and measure type 1 diabetes trajectory.

JCI Insight 2019 Mar 21;4(6). Epub 2019 Mar 21.

Department of Surgery, University of British Columbia (UBC), and BC Children's Hospital Research Institute (BCCHRI), Vancouver, British Columbia, Canada.

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http://insight.jci.org/articles/view/123879
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http://dx.doi.org/10.1172/jci.insight.123879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483004PMC
March 2019

Characterization of regulatory T cells in obese omental adipose tissue in humans.

Eur J Immunol 2019 Feb 8;49(2):336-347. Epub 2019 Jan 8.

Department of Surgery, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/eji.201847570DOI Listing
February 2019

Analysis of pancreatic beta cell specific CD4+ T cells reveals a predominance of proinsulin specific cells.

Cell Immunol 2019 01 7;335:68-75. Epub 2018 Nov 7.

Translational Research Program, Benaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2018.11.004DOI Listing
January 2019

Attenuated IL-2R signaling in CD4 memory T cells of T1D subjects is intrinsic and dependent on activation state.

Clin Immunol 2017 08 20;181:67-74. Epub 2017 Jun 20.

Translational Research Program, Benaroya Research Institute, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2017.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564451PMC
August 2017

Measurement of Pro-Islet Amyloid Polypeptide (1-48) in Diabetes and Islet Transplants.

J Clin Endocrinol Metab 2017 07;102(7):2595-2603

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada.

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http://dx.doi.org/10.1210/jc.2016-2773DOI Listing
July 2017

The Relationship of Immune Cell Signatures to Patient Survival Varies within and between Tumor Types.

PLoS One 2015 23;10(9):e0138726. Epub 2015 Sep 23.

Department of Systems Immunology, Benaroya Research Institute, 1201 Ninth Avenue, Seattle, WA 98101-2795, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138726PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580625PMC
June 2016

Evaluation of Candidate Biomarkers of Type 1 Diabetes via the Core for Assay Validation.

Biomark Insights 2015 29;10(Suppl 4):19-24. Epub 2015 Sep 29.

Diabetes Clinical Research Program, Benaroya Research Institute, Seattle, WA, USA.

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http://dx.doi.org/10.4137/BMI.S29697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589091PMC
October 2015

Copy number loss of the interferon gene cluster in melanomas is linked to reduced T cell infiltrate and poor patient prognosis.

PLoS One 2014 14;9(10):e109760. Epub 2014 Oct 14.

Department of Systems Immunology, Benaroya Research Institute, Seattle, WA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0109760PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196925PMC
June 2015

Low HERV-K(C4) copy number is associated with type 1 diabetes.

Diabetes 2014 May 15;63(5):1789-95. Epub 2014 Jan 15.

Systems Immunology, Benaroya Research Institute, Seattle, WA.

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http://dx.doi.org/10.2337/db13-1382DOI Listing
May 2014

Malaria sporozoite proteome leaves a trail.

Genome Biol 2009 21;10(4):216. Epub 2009 Apr 21.

Malaria Program, Seattle Biomedical Research Institute, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1186/gb-2009-10-4-216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688921PMC
September 2009