Case W McNamara

Case W McNamara

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Case W McNamara

Case W McNamara

Publications by authors named "Case W McNamara"

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High-Content Screening for Cryptosporidium Drug Discovery.

Methods Mol Biol 2020 ;2052:303-317

Calibr at Scripps Research, La Jolla, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-9748-0_17DOI Listing
January 2020

The Deconstructed Granuloma: A Complex High-Throughput Drug Screening Platform for the Discovery of Host-Directed Therapeutics Against Tuberculosis.

Front Cell Infect Microbiol 2018 14;8:275. Epub 2018 Aug 14.

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States.

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http://dx.doi.org/10.3389/fcimb.2018.00275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102409PMC
August 2019

Novel chemical starting points for drug discovery in leishmaniasis and Chagas disease.

Int J Parasitol Drugs Drug Resist 2019 Aug 22;10:58-68. Epub 2019 May 22.

Calibr at Scripps Research, La Jolla, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ijpddr.2019.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545338PMC
August 2019

Advances in Antiwolbachial Drug Discovery for Treatment of Parasitic Filarial Worm Infections.

Trop Med Infect Dis 2019 Jul 18;4(3). Epub 2019 Jul 18.

Calibr at Scripps Research, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.3390/tropicalmed4030108DOI Listing
July 2019

Discovery of Kirromycins with Anti- Wolbachia Activity from Streptomyces sp. CB00686.

ACS Chem Biol 2019 Jun 10;14(6):1174-1182. Epub 2019 May 10.

Department of Chemistry , The Scripps Research Institute , Jupiter , Florida 33458 , United States.

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http://dx.doi.org/10.1021/acschembio.9b00086DOI Listing
June 2019

Antibacterial Oligomeric Polyphenols from the Green Alga Cladophora socialis.

J Org Chem 2019 May 3;84(9):5035-5045. Epub 2019 Apr 3.

Aquatic Chemical Ecology Center , Georgia Institute of Technology , Atlanta , Georgia 30332 , United States.

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http://pubs.acs.org/doi/10.1021/acs.joc.8b03218
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http://dx.doi.org/10.1021/acs.joc.8b03218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503470PMC
May 2019

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.

Proc Natl Acad Sci U S A 2019 04 20;116(14):7015-7020. Epub 2019 Mar 20.

Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1814685116
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http://dx.doi.org/10.1073/pnas.1814685116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452685PMC
April 2019

Herbicidins from Streptomyces sp. CB01388 Showing Anti- Cryptosporidium Activity.

J Nat Prod 2018 04 22;81(4):791-797. Epub 2018 Feb 22.

Department of Chemistry , The Scripps Research Institute , Jupiter , Florida 33458 , United States.

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http://dx.doi.org/10.1021/acs.jnatprod.7b00850DOI Listing
April 2018

A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis.

PLoS Negl Trop Dis 2017 02 3;11(2):e0005373. Epub 2017 Feb 3.

California Institute for Biomedical Research, La Jolla, California, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0005373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310922PMC
February 2017

High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria.

ACS Infect Dis 2016 Apr 10;2(4):281-293. Epub 2016 Feb 10.

School of Medicine, Department of Pediatrics, Pharmacology & Drug Discovery, University of California, San Diego , 9500 Gilman Drive, La Jolla, California 92093, United States.

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http://dx.doi.org/10.1021/acsinfecdis.5b00143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890880PMC
April 2016

Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease.

PLoS Pathog 2015 Jul 17;11(7):e1005058. Epub 2015 Jul 17.

Department of Genetics and Neglected Diseases, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506092PMC
July 2015

Mutations in the P-type cation-transporter ATPase 4, PfATP4, mediate resistance to both aminopyrazole and spiroindolone antimalarials.

ACS Chem Biol 2015 Feb 5;10(2):413-20. Epub 2014 Nov 5.

Division of Pharmacology and Drug Discovery, Department of Pediatrics, ‡Division of Infectious Diseases, Department of Medicine, University of California San Diego School of Medicine , La Jolla, California 92093, United States.

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http://dx.doi.org/10.1021/cb500616xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340351PMC
February 2015

Identification of pathogen genomic variants through an integrated pipeline.

BMC Bioinformatics 2014 Mar 3;15:63. Epub 2014 Mar 3.

Department of Pediatrics, University of California, San Diego, School of Medicine, 9500 Gilman Drive 0741, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1186/1471-2105-15-63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945619PMC
March 2014

A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor.

ACS Chem Biol 2011 Nov 8;6(11):1214-22. Epub 2011 Sep 8.

Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

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http://dx.doi.org/10.1021/cb200105dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220786PMC
November 2011