Caryn Lerman

Caryn Lerman

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Caryn Lerman

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Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activity.

Authors:
Ahmed El-Boraie Taraneh Taghavi Meghan J Chenoweth Koya Fukunaga Taisei Mushiroda Michiaki Kubo Caryn Lerman Nicole L Nollen Neal L Benowitz Rachel F Tyndale

Addict Biol 2020 Jan 27;25(1):e12741. Epub 2019 Feb 27.

Department of Pharmacology and Toxicology, University of Toronto, Toronto, M5S 1A8, Canada.

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http://dx.doi.org/10.1111/adb.12741DOI Listing
January 2020

Toward Precision Medicine for Smoking Cessation: Developing a Neuroimaging-Based Classification Algorithm to Identify Smokers at Higher Risk for Relapse.

Authors:
David W Frank Paul M Cinciripini Menton M Deweese Maher Karam-Hage George Kypriotakis Caryn Lerman Jason D Robinson Rachel F Tyndale Damon J Vidrine Francesco Versace

Nicotine Tob Res 2019 Nov 14. Epub 2019 Nov 14.

Department of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1093/ntr/ntz211DOI Listing
November 2019

Impact of early nausea on varenicline adherence and smoking cessation.

Authors:
Annie R Peng Walter Swardfager Neal L Benowitz Jasjit S Ahluwalia Caryn Lerman Nicole L Nollen Rachel F Tyndale

Addiction 2019 Sep 10. Epub 2019 Sep 10.

Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/add.14810DOI Listing
September 2019

Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes.

Authors:
Jingchun Chen Anu Loukola Nathan A Gillespie Roseann Peterson Peilin Jia Brien Riley Hermine Maes Daniella M Dick Kenneth S Kendler M Imad Damaj Michael F Miles Zhongming Zhao Ming D Li Jacqueline M Vink Camelia C Minica Gonneke Willemsen Dorret I Boomsma Beenish Qaiser Pamela A F Madden Tellervo Korhonen Pekka Jousilahti Jenni Hällfors Joel Gelernter Henry R Kranzler Richard Sherva Lindsay Farrer Brion Maher Michael Vanyukov Michelle Taylor Jenifer J Ware Marcus R Munafò Sharon M Lutz John E Hokanson Fangyi Gu Maria T Landi Neil E Caporaso Dana B Hancock Nathan C Gaddis Timothy B Baker Laura J Bierut Eric O Johnson Meghan Chenoweth Caryn Lerman Rachel Tyndale Jaakko Kaprio Xiangning Chen

Nicotine Tob Res 2019 Jul 11. Epub 2019 Jul 11.

Nevada Institute of Personalized Medicine, University of Nevada Las Vegas, Las Vegas, NV.

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http://dx.doi.org/10.1093/ntr/ntz099DOI Listing
July 2019

Differences in the rate of nicotine metabolism among smokers with and without HIV.

Authors:
Rebecca L Ashare Morgan Thompson Frank Leone David Metzger Robert Gross Karam Mounzer Rachel F Tyndale Caryn Lerman Martin C Mahoney Paul Cinciripini Tony P George Ronald G Collman Robert Schnoll

AIDS 2019 May;33(6):1083-1088

Department of Psychiatry, University of Pennsylvania Perelman School of Medicine.

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http://dx.doi.org/10.1097/QAD.0000000000002127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457129PMC
May 2019

Brain Marker Links Stress and Nicotine Abstinence.

Authors:
Cheyenne Allenby Mary Falcone Rebecca L Ashare Wen Cao Leah Bernardo E Paul Wileyto Jens Pruessner James Loughead Caryn Lerman

Nicotine Tob Res 2019 May 22. Epub 2019 May 22.

Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1093/ntr/ntz077DOI Listing
May 2019

Transcranial direct current brain stimulation decreases impulsivity in ADHD.

Authors:
Cheyenne Allenby Mary Falcone Leah Bernardo E Paul Wileyto Anthony Rostain J Russell Ramsay Caryn Lerman James Loughead

Brain Stimul 2018 Sep - Oct;11(5):974-981. Epub 2018 Apr 23.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2018.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109423PMC
March 2019

Evaluating the temporal relationships between withdrawal symptoms and smoking relapse.

Authors:
Jason D Robinson Liang Li Minxing Chen Caryn Lerman Rachel F Tyndale Robert A Schnoll Larry W Hawk Tony P George Neal L Benowitz Paul M Cinciripini

Psychol Addict Behav 2019 Mar 7;33(2):105-116. Epub 2019 Jan 7.

Department of Behavioral Science.

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http://doi.apa.org/getdoi.cfm?doi=10.1037/adb0000434
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http://dx.doi.org/10.1037/adb0000434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405298PMC
March 2019

Neural cue reactivity during acute abstinence predicts short-term smoking relapse.

Authors:
Cheyenne Allenby Mary Falcone E Paul Wileyto Wen Cao Leah Bernardo Rebecca L Ashare Amy Janes James Loughead Caryn Lerman

Addict Biol 2019 Feb 25. Epub 2019 Feb 25.

Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/adb.12733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708755PMC
February 2019

Lack of effect of transcranial direct current stimulation (tDCS) on short-term smoking cessation: Results of a randomized, sham-controlled clinical trial.

Authors:
Mary Falcone Leah Bernardo E Paul Wileyto Cheyenne Allenby Anne Marie Burke Roy Hamilton Mario Cristancho Rebecca L Ashare James Loughead Caryn Lerman

Drug Alcohol Depend 2019 01 13;194:244-251. Epub 2018 Nov 13.

Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.drugalcdep.2018.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312458PMC
January 2019

Got chocolate? Bilateral prefrontal cortex stimulation augments chocolate consumption.

Authors:
Chan To Mary Falcone James Loughead Erin Logue-Chamberlain Roy Hamilton Joseph Kable Caryn Lerman Rebecca L Ashare

Appetite 2018 12 29;131:28-35. Epub 2018 Aug 29.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01956663183049
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http://dx.doi.org/10.1016/j.appet.2018.08.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197906PMC
December 2018

Predicting smoking abstinence with biological and self-report measures of adherence to varenicline: Impact on pharmacogenetic trial outcomes.

Authors:
Annie R Peng Robert Schnoll Larry W Hawk Paul Cinciripini Tony P George Caryn Lerman Rachel F Tyndale

Drug Alcohol Depend 2018 09 26;190:72-81. Epub 2018 Jun 26.

Department of Pharmacology and Toxicology, University of Toronto, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada; Addictions Division, Centre for Addiction and Mental Health and Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, 100 Stokes Street BGB 3288, Toronto, ON, M6J 1H4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2018.04.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085881PMC
September 2018

A Comparison of Direct and Indirect Analytical Approaches to Measuring Total Nicotine Equivalents in Urine.

Authors:
Taraneh Taghavi Maria Novalen Caryn Lerman Tony P George Rachel F Tyndale

Cancer Epidemiol Biomarkers Prev 2018 08 31;27(8):882-891. Epub 2018 May 31.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072604PMC
August 2018

Association of Reduced Nicotine Content Cigarettes With Smoking Behaviors and Biomarkers of Exposure Among Slow and Fast Nicotine Metabolizers: A Nonrandomized Clinical Trial.

Authors:
Melissa Mercincavage Kirsten Lochbuehler E Paul Wileyto Neal L Benowitz Rachel F Tyndale Caryn Lerman Andrew A Strasser

JAMA Netw Open 2018 08 24;1(4):e181346. Epub 2018 Aug 24.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1001/jamanetworkopen.2018.1346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322845PMC
August 2018

Leadership Development in Medicine.

Authors:
Caryn Lerman J Larry Jameson

N Engl J Med 2018 May;378(20):1862-1863

From the Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1056/NEJMp1801610DOI Listing
May 2018

What a medical school chair wants from the dean.

Authors:
Robert Hromas Robert Leverence Lazarus K Mramba J Larry Jameson Caryn Lerman Thomas L Schwenk Ellen M Zimmermann Michael L Good

J Healthc Leadersh 2018 23;10:33-44. Epub 2018 May 23.

Department of Anesthesiology, College of Medicine, University of Florida Health, Gainesville, FL, USA.

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http://dx.doi.org/10.2147/JHL.S158937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973440PMC
May 2018

Improvement of the association between self-reported pill count and varenicline levels following exclusion of participants with misreported pill count: A commentary on Peng et al. (2017).

Authors:
Annie R Peng Bernard Le Foll Mark Morales Caryn Lerman Robert Schnoll Rachel F Tyndale

Addict Behav 2018 04 2;79:14-16. Epub 2017 Dec 2.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.addbeh.2017.11.032DOI Listing
April 2018

Amygdala Functional and Structural Connectivity Predicts Individual Risk Tolerance.

Authors:
Wi Hoon Jung Sangil Lee Caryn Lerman Joseph W Kable

Neuron 2018 04 5;98(2):394-404.e4. Epub 2018 Apr 5.

Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.03.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910234PMC
April 2018

Genome-wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences.

Authors:
Meghan J Chenoweth Jennifer J Ware Andy Z X Zhu Christopher B Cole Lisa Sanderson Cox Nikki Nollen Jasjit S Ahluwalia Neal L Benowitz Robert A Schnoll Larry W Hawk Paul M Cinciripini Tony P George Caryn Lerman Joanne Knight Rachel F Tyndale

Addiction 2018 03 2;113(3):509-523. Epub 2017 Nov 2.

Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/add.14032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807179PMC
March 2018

Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism.

Authors:
Julie-Anne Tanner Andy Z Zhu Katrina G Claw Bhagwat Prasad Viktoriya Korchina Jianhong Hu HarshaVardhan Doddapaneni Donna M Muzny Erin G Schuetz Caryn Lerman Kenneth E Thummel Steven E Scherer Rachel F Tyndale

Pharmacogenet Genomics 2018 Jan;28(1):7-16

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH).

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http://dx.doi.org/10.1097/FPC.0000000000000317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729933PMC
January 2018

Measures and predictors of varenicline adherence in the treatment of nicotine dependence.

Authors:
Annie R Peng Mark Morales E Paul Wileyto Larry W Hawk Paul Cinciripini Tony P George Neal L Benowitz Nicole L Nollen Caryn Lerman Rachel F Tyndale Robert Schnoll

Addict Behav 2017 12 12;75:122-129. Epub 2017 Jul 12.

Department of Psychiatry, Abramson Cancer Center, University of Pennsylvania, 3535 Market Street, Philadelphia, PA 19104, United States. Electronic address:

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http://dx.doi.org/10.1016/j.addbeh.2017.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581992PMC
December 2017

No Effect of Commercial Cognitive Training on Brain Activity, Choice Behavior, or Cognitive Performance.

Authors:
Joseph W Kable M Kathleen Caulfield Mary Falcone Mairead McConnell Leah Bernardo Trishala Parthasarathi Nicole Cooper Rebecca Ashare Janet Audrain-McGovern Robert Hornik Paul Diefenbach Frank J Lee Caryn Lerman

J Neurosci 2017 08 10;37(31):7390-7402. Epub 2017 Jul 10.

Psychiatry, and.

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http://dx.doi.org/10.1523/JNEUROSCI.2832-16.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546110PMC
August 2017

Sleep Disturbance During Smoking Cessation: Withdrawal or Side Effect of Treatment?

Authors:
Rebecca L Ashare Caryn Lerman Rachel F Tyndale Larry W Hawk Tony P George Paul Cinciripini Robert A Schnoll

J Smok Cessat 2017 Jun 12;12(2):63-70. Epub 2016 Apr 12.

Department of Psychiatry and Abramson Cancer Center, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA, 19104.

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http://dx.doi.org/10.1017/jsc.2016.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443250PMC
June 2017

Transcranial Direct Current Brain Stimulation Increases Ability to Resist Smoking.

Authors:
Mary Falcone Leah Bernardo Rebecca L Ashare Roy Hamilton Olufunsho Faseyitan Sherry A McKee James Loughead Caryn Lerman

Brain Stimul 2016 Mar-Apr;9(2):191-6. Epub 2015 Oct 23.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.brs.2015.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789149PMC
February 2017

Translational Research on Nicotine Dependence.

Authors:
Mary Falcone Bridgin Lee Caryn Lerman Julie A Blendy

Curr Top Behav Neurosci 2016;28:121-50

Department of Pharmacology, University of Pennsylvania, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/7854_2015_5005DOI Listing
December 2016

Can brain games help smokers quit?: Results of a randomized clinical trial.

Authors:
James Loughead Mary Falcone E Paul Wileyto Benjamin Albelda Janet Audrain-McGovern Wen Cao Matthew M Kurtz Ruben C Gur Caryn Lerman

Drug Alcohol Depend 2016 Nov 27;168:112-118. Epub 2016 Aug 27.

Department of Psychiatry, University of PA, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2016.08.621DOI Listing
November 2016

Precision Medicine for Tobacco Dependence: Development and Validation of the Nicotine Metabolite Ratio.

Authors:
Cheyenne E Allenby Kelly A Boylan Caryn Lerman Mary Falcone

J Neuroimmune Pharmacol 2016 09 12;11(3):471-83. Epub 2016 Feb 12.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s11481-016-9656-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479354PMC
September 2016

Racial differences in the relationship between rate of nicotine metabolism and nicotine intake from cigarette smoking.

Authors:
Kathryn C Ross Noah R Gubner Rachel F Tyndale Larry W Hawk Caryn Lerman Tony P George Paul Cinciripini Robert A Schnoll Neal L Benowitz

Pharmacol Biochem Behav 2016 09 11;148:1-7. Epub 2016 May 11.

Center for Tobacco Control Research and Education, University of California San Francisco, San Francisco, CA, USA; Division of Clinical Pharmacology and Experimental Therapeutics, Department of Medicine, University of California San Francisco, San Francisco, CA, USA; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pbb.2016.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972680PMC
September 2016

Brain Responses to Smoking Cues Differ Based on Nicotine Metabolism Rate.

Authors:
Mary Falcone Wen Cao Leah Bernardo Rachel F Tyndale James Loughead Caryn Lerman

Biol Psychiatry 2016 08 26;80(3):190-7. Epub 2015 Nov 26.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2015.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625335PMC
August 2016

Nicotine withdrawal alters neural responses to psychosocial stress.

Authors:
Rebecca L Ashare Caryn Lerman Wen Cao Mary Falcone Leah Bernardo Kosha Ruparel Ryan Hopson Ruben Gur Jens C Pruessner James Loughead

Psychopharmacology (Berl) 2016 07 18;233(13):2459-67. Epub 2016 Apr 18.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, 3535 Market St., Suite 4100, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s00213-016-4299-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907902PMC
July 2016

Does cannabis use moderate smoking cessation outcomes in treatment-seeking tobacco smokers? Analysis from a large multi-center trial.

Authors:
Rachel A Rabin Rebecca L Ashare Robert A Schnoll Paul M Cinciripini Larry W Hawk Caryn Lerman Rachel F Tyndale Tony P George

Am J Addict 2016 06 17;25(4):291-6. Epub 2016 May 17.

The Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/ajad.12382DOI Listing
June 2016

Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline Smoking.

Authors:
Rachel F Tyndale Andy Z X Zhu Tony P George Paul Cinciripini Larry W Hawk Robert A Schnoll Gary E Swan Neal L Benowitz Daniel F Heitjan Caryn Lerman

PLoS One 2015 26;10(5):e0128109. Epub 2015 May 26.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128109PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444267PMC
April 2016

The Nicotine Metabolite Ratio is Associated With Early Smoking Abstinence Even After Controlling for Factors That Influence the Nicotine Metabolite Ratio.

Authors:
Meghan J Chenoweth Robert A Schnoll Maria Novalen Larry W Hawk Tony P George Paul M Cinciripini Caryn Lerman Rachel F Tyndale

Nicotine Tob Res 2016 Apr 11;18(4):491-5. Epub 2015 Jun 11.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada

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http://dx.doi.org/10.1093/ntr/ntv125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220835PMC
April 2016

Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption.

Authors:
Andrew W Bergen Martha Michel Denise Nishita Ruth Krasnow Harold S Javitz Karen N Conneely Christina N Lessov-Schlaggar Hyman Hops Andy Z X Zhu James W Baurley Jennifer B McClure Sharon M Hall Timothy B Baker David V Conti Neal L Benowitz Caryn Lerman Rachel F Tyndale Gary E Swan

PLoS One 2015 1;10(7):e0126113. Epub 2015 Jul 1.

Oregon Research Institute, Eugene, Oregon, United States of America; Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Palo Alto, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126113PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488893PMC
April 2016

Initial Evaluation of Fenofibrate for Efficacy in Aiding Smoking Abstinence.

Authors:
Kenneth A Perkins Joshua L Karelitz Valerie C Michael Margaret Fromuth Cynthia A Conklin K N Roy Chengappa Chris Hope Caryn Lerman

Nicotine Tob Res 2016 Jan 20;18(1):74-8. Epub 2015 Apr 20.

Department of Psychiatry and Abramson Cancer Center, University of Pennsylvania, Philadelphia PA.

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https://academic.oup.com/ntr/article-lookup/doi/10.1093/ntr/
Publisher Site
http://dx.doi.org/10.1093/ntr/ntv085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881827PMC
January 2016

Test-Retest Reliability and Stability of the Nicotine Metabolite Ratio Among Treatment-Seeking Smokers.

Authors:
Diana A Hamilton Martin C Mahoney Maria Novalen Meghan J Chenoweth Daniel F Heitjan Caryn Lerman Rachel F Tyndale Larry W Hawk

Nicotine Tob Res 2015 Dec 1;17(12):1505-9. Epub 2015 Mar 1.

Department of Psychology, University at Buffalo, SUNY, Buffalo, NY;

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http://dx.doi.org/10.1093/ntr/ntv031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654759PMC
December 2015

Decreased Nicotinic Receptor Availability in Smokers with Slow Rates of Nicotine Metabolism.

Authors:
Jacob G Dubroff Robert K Doot Mary Falcone Robert A Schnoll Riju Ray Rachel F Tyndale Arthur L Brody Catherine Hou Alexander Schmitz Caryn Lerman

J Nucl Med 2015 Nov 13;56(11):1724-9. Epub 2015 Aug 13.

Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.2967/jnumed.115.155002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646418PMC
November 2015

RNA sequencing of transcriptomes in human brain regions: protein-coding and non-coding RNAs, isoforms and alleles.

Authors:
Amy Webb Audrey C Papp Amanda Curtis Leslie C Newman Maciej Pietrzak Michal Seweryn Samuel K Handelman Grzegorz A Rempala Daqing Wang Erica Graziosa Rachel F Tyndale Caryn Lerman John R Kelsoe Deborah C Mash Wolfgang Sadee

BMC Genomics 2015 Nov 23;16:990. Epub 2015 Nov 23.

Center for Pharmacogenomics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA.

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http://dx.doi.org/10.1186/s12864-015-2207-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657279PMC
November 2015

Nicotine metabolite ratio (3-hydroxycotinine/cotinine) in plasma and urine by different analytical methods and laboratories: implications for clinical implementation.

Authors:
Julie-Anne Tanner Maria Novalen Peter Jatlow Marilyn A Huestis Sharon E Murphy Jaakko Kaprio Aino Kankaanpää Laurence Galanti Cristiana Stefan Tony P George Neal L Benowitz Caryn Lerman Rachel F Tyndale

Cancer Epidemiol Biomarkers Prev 2015 Aug 26;24(8):1239-46. Epub 2015 May 26.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada. Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. Schizophrenia Division, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1055-9965.EPI-14-1381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526326PMC
August 2015

Working memory-related neural activity predicts future smoking relapse.

Authors:
James Loughead E Paul Wileyto Kosha Ruparel Mary Falcone Ryan Hopson Ruben Gur Caryn Lerman

Neuropsychopharmacology 2015 May 3;40(6):1311-20. Epub 2014 Dec 3.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/npp.2014.318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397393PMC
May 2015

Use of the nicotine metabolite ratio as a genetically informed biomarker of response to nicotine patch or varenicline for smoking cessation: a randomised, double-blind placebo-controlled trial.

Authors:
Caryn Lerman Robert A Schnoll Larry W Hawk Paul Cinciripini Tony P George E Paul Wileyto Gary E Swan Neal L Benowitz Daniel F Heitjan Rachel F Tyndale

Lancet Respir Med 2015 Feb 12;3(2):131-138. Epub 2015 Jan 12.

Centre for Addiction and Mental Health and Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/S2213-2600(14)70294-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480925PMC
February 2015

Age-related differences in working memory deficits during nicotine withdrawal.

Authors:
Mary Falcone E Paul Wileyto Kosha Ruparel Raphael T Gerraty Leah LaPrate John A Detre Ruben Gur James Loughead Caryn Lerman

Addict Biol 2014 Sep 18;19(5):907-17. Epub 2013 Mar 18.

Department of Pharmacology, University of Pennsylvania, Philadelphia, PA, USA; Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.

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http://doi.wiley.com/10.1111/adb.12051
Publisher Site
http://dx.doi.org/10.1111/adb.12051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701751PMC
September 2014

Known and novel sources of variability in the nicotine metabolite ratio in a large sample of treatment-seeking smokers.

Authors:
Meghan J Chenoweth Maria Novalen Larry W Hawk Robert A Schnoll Tony P George Paul M Cinciripini Caryn Lerman Rachel F Tyndale

Cancer Epidemiol Biomarkers Prev 2014 Sep 10;23(9):1773-82. Epub 2014 Jul 10.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada. Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1055-9965.EPI-14-0427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154993PMC
September 2014

Large-scale brain network coupling predicts acute nicotine abstinence effects on craving and cognitive function.

Authors:
Caryn Lerman Hong Gu James Loughead Kosha Ruparel Yihong Yang Elliot A Stein

JAMA Psychiatry 2014 May;71(5):523-30

Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland.

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http://dx.doi.org/10.1001/jamapsychiatry.2013.4091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097018PMC
May 2014

Nicotine dependence as a moderator of genetic influences on smoking cessation treatment outcome.

Authors:
Adam M Leventhal Wonho Lee Andrew W Bergen Gary E Swan Rachel F Tyndale Caryn Lerman David V Conti

Drug Alcohol Depend 2014 May 5;138:109-17. Epub 2014 Mar 5.

Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1016/j.drugalcdep.2014.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095777PMC
May 2014

Cognitive function during nicotine withdrawal: Implications for nicotine dependence treatment.

Authors:
Rebecca L Ashare Mary Falcone Caryn Lerman

Neuropharmacology 2014 Jan 29;76 Pt B:581-91. Epub 2013 Apr 29.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2013.04.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779499PMC
January 2014

An efficient early phase 2 procedure to screen medications for efficacy in smoking cessation.

Authors:
Kenneth A Perkins Caryn Lerman

Psychopharmacology (Berl) 2014 Jan 3;231(1):1-11. Epub 2013 Dec 3.

Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA,

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http://dx.doi.org/10.1007/s00213-013-3364-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910509PMC
January 2014

Association of abstinence-induced alterations in working memory function and COMT genotype in smokers.

Authors:
Rebecca L Ashare Jeffrey N Valdez Kosha Ruparel Benjamin Albelda Ryan D Hopson John R Keefe James Loughead Caryn Lerman

Psychopharmacology (Berl) 2013 Dec 5;230(4):653-62. Epub 2013 Jul 5.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA, 19104, USA,

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http://dx.doi.org/10.1007/s00213-013-3197-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840089PMC
December 2013

Influence of a dopamine pathway additive genetic efficacy score on smoking cessation: results from two randomized clinical trials of bupropion.

Authors:
Sean P David David R Strong Adam M Leventhal Molly A Lancaster John E McGeary Marcus R Munafò Andrew W Bergen Gary E Swan Neal L Benowitz Rachel F Tyndale David V Conti Richard A Brown Caryn Lerman Raymond Niaura

Addiction 2013 Dec 18;108(12):2202-11. Epub 2013 Sep 18.

Stanford University School of Medicine, Center for Education and Research in Family and Community Medicine, Division of General Medical Disciplines, Department of Medicine, Stanford, CA, USA; SRI International, Center for Health Sciences, Menlo Park, CA, USA; Alpert Medical School of Brown University, Department of Family Medicine, Pawtucket, RI, USA.

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http://dx.doi.org/10.1111/add.12325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834197PMC
December 2013

Effects of tolcapone on working memory and brain activity in abstinent smokers: a proof-of-concept study.

Authors:
Rebecca L Ashare E Paul Wileyto Kosha Ruparel Patricia M Goelz Ryan D Hopson Jeffrey N Valdez Ruben C Gur James Loughead Caryn Lerman

Drug Alcohol Depend 2013 Dec 14;133(3):852-6. Epub 2013 Sep 14.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2013.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960598PMC
December 2013

Applying Quantitative Approaches to the Formative Evaluation of Antismoking Campaign Messages.

Authors:
Sarah Parvanta Laura Gibson Heather Forquer Dina Shapiro-Luft Lorraine Dean Derek Freres Caryn Lerman Giridhar Mallya Mihaela Moldovan-Johnson Andy Tan Joseph Cappella Robert Hornik

Soc Mar Q 2013 Dec;19(4):242-264

Annenberg School for Communication, University of Pennsylvania, Philadelphia, PA, USA.

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http://journals.sagepub.com/doi/10.1177/1524500413506004
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http://dx.doi.org/10.1177/1524500413506004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012855PMC
December 2013

Effects of bupropion on cognitive performance during initial tobacco abstinence.

Authors:
Kenneth A Perkins Joshua L Karelitz Nancy C Jao Ruben C Gur Caryn Lerman

Drug Alcohol Depend 2013 Nov 31;133(1):283-6. Epub 2013 May 31.

Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03768716130017
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http://dx.doi.org/10.1016/j.drugalcdep.2013.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786016PMC
November 2013

No untoward effects of smoking cues in anti-smoking public service announcements.

Authors:
Mary Falcone Caryn Lerman Joseph N Cappella Paul Sanborn Christopher Jepson Andrew A Strasser

Drug Alcohol Depend 2013 Nov 3;133(1):279-82. Epub 2013 Jun 3.

Department of Pharmacology, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.drugalcdep.2013.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786034PMC
November 2013

Sensitivity and specificity of a procedure for early human screening of novel smoking cessation medications.

Authors:
Kenneth A Perkins Caryn Lerman Joshua L Karelitz Nancy C Jao K N Roy Chengappa Garrett M Sparks

Addiction 2013 Nov 12;108(11):1962-8. Epub 2013 Jul 12.

Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.

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http://doi.wiley.com/10.1111/add.12273
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797155PMC
November 2013

Neuroimaging in psychiatric pharmacogenetics research: the promise and pitfalls.

Authors:
Mary Falcone Ryan M Smith Meghan J Chenoweth Abesh Kumar Bhattacharjee John R Kelsoe Rachel F Tyndale Caryn Lerman

Neuropsychopharmacology 2013 Nov 24;38(12):2327-37. Epub 2013 Jun 24.

1] Department of Pharmacology, University of Pennsylvania, Philadelphia, PA, USA [2] Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.

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http://www.nature.com/articles/npp2013152
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http://dx.doi.org/10.1038/npp.2013.152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799069PMC
November 2013

Brain activity and emotional processing in smokers treated with varenicline.

Authors:
James Loughead Riju Ray E Paul Wileyto Kosha Ruparel Gregory P O'Donnell Nicole Senecal Steven Siegel Ruben C Gur Caryn Lerman

Addict Biol 2013 Jul 20;18(4):732-8. Epub 2011 Apr 20.

Brain Behavior Laboratory, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1111/j.1369-1600.2011.00324.xDOI Listing
July 2013

The DRD4 exon III VNTR, bupropion, and associations with prospective abstinence.

Authors:
Andrew W Bergen Harold S Javitz Li Su Yungang He David V Conti Neal L Benowitz Rachel F Tyndale Caryn Lerman Gary E Swan

Nicotine Tob Res 2013 Jul 3;15(7):1190-200. Epub 2012 Dec 3.

Center for Health Sciences, SRI International, Menlo Park, CA 94025, USA.

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http://dx.doi.org/10.1093/ntr/nts245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682839PMC
July 2013

Nicotine receptor subtype-specific effects on auditory evoked oscillations and potentials.

Authors:
Robert E Featherstone Jennifer M Phillips Tony Thieu Richard S Ehrlichman Tobias B Halene Steven C Leiser Edward Christian Edwin Johnson Caryn Lerman Steven J Siegel

PLoS One 2012 20;7(7):e39775. Epub 2012 Jul 20.

Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039775PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401200PMC
April 2013

The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race, and sex.

Authors:
Andy Z X Zhu Caroline C Renner Dorothy K Hatsukami Gary E Swan Caryn Lerman Neal L Benowitz Rachel F Tyndale

Cancer Epidemiol Biomarkers Prev 2013 Apr 31;22(4):708-18. Epub 2013 Jan 31.

Departments of Psychiatry, Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1055-9965.EPI-12-1234-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617060PMC
April 2013

Content matters: neuroimaging investigation of brain and behavioral impact of televised anti-tobacco public service announcements.

Authors:
An-Li Wang Kosha Ruparel James W Loughead Andrew A Strasser Shira J Blady Kevin G Lynch Dan Romer Joseph N Cappella Caryn Lerman Daniel D Langleben

J Neurosci 2013 Apr;33(17):7420-7

Annenberg Public Policy Center, Department of Psychiatry, and Annenberg School for Communication, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3840-12.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773220PMC
April 2013

Effects of smoking cues and argument strength of antismoking advertisements on former smokers' self-efficacy, attitude, and intention to refrain from smoking.

Authors:
Sungkyoung Lee Joseph N Cappella Caryn Lerman Andrew A Strasser

Nicotine Tob Res 2013 Feb 4;15(2):527-33. Epub 2012 Sep 4.

Center of Excellence in Cancer Communication Research, Annenberg School for Communication, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/ntr/nts171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545718PMC
February 2013

Nicotinic acetylcholine receptor variation and response to smoking cessation therapies.

Authors:
Andrew W Bergen Harold S Javitz Ruth Krasnow Denise Nishita Martha Michel David V Conti Jinghua Liu Won Lee Christopher K Edlund Sharon Hall Pui-Yan Kwok Neal L Benowitz Timothy B Baker Rachel F Tyndale Caryn Lerman Gary E Swan

Pharmacogenet Genomics 2013 Feb;23(2):94-103

Center for Health Sciences, SRI International, Menlo Park, CA 94025, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32835cdabdDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563676PMC
February 2013

Smoking in response to negative mood in men versus women as a function of distress tolerance.

Authors:
Kenneth A Perkins Grace E Giedgowd Joshua L Karelitz Cynthia A Conklin Caryn Lerman

Nicotine Tob Res 2012 Dec 13;14(12):1418-25. Epub 2012 Mar 13.

Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1093/ntr/nts075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509012PMC
December 2012

Cognitive effects of the acetylcholinesterase inhibitor, donepezil, in healthy, non-treatment seeking smokers: a pilot feasibility study.

Authors:
Rebecca L Ashare Riju Ray Caryn Lerman Andrew A Strasser

Drug Alcohol Depend 2012 Nov 15;126(1-2):263-7. Epub 2012 May 15.

University of Pennsylvania Perelman School of Medicine, Department of Psychiatry, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.drugalcdep.2012.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424358PMC
November 2012

Comparative dynamics of four smoking withdrawal symptom scales.

Authors:
Harold S Javitz Caryn Lerman Gary E Swan

Addiction 2012 Aug 17;107(8):1501-11. Epub 2012 Apr 17.

Center for Health Sciences, SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025, USA.

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http://dx.doi.org/10.1111/j.1360-0443.2012.03838.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394903PMC
August 2012

μ-Opioid receptor availability in the amygdala is associated with smoking for negative affect relief.

Authors:
Mary Falcone Allison B Gold E Paul Wileyto Riju Ray Kosha Ruparel Andrew Newberg Jacob Dubroff Jean Logan Jon-Kar Zubieta Julie A Blendy Caryn Lerman

Psychopharmacology (Berl) 2012 Aug 3;222(4):701-8. Epub 2012 Mar 3.

Department of Pharmacology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1007/s00213-012-2673-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670416PMC
August 2012

DRD1 associations with smoking abstinence across slow and normal nicotine metabolizers.

Authors:
Wonho Lee Riju Ray Andrew W Bergen Gary E Swan Paul Thomas Rachel F Tyndale Neal L Benowitz Caryn Lerman David V Conti

Pharmacogenet Genomics 2012 Jul;22(7):551-4

Department of Preventive Medicine, University of Southern California, Los Angeles, USA.

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http://dx.doi.org/10.1097/FPC.0b013e3283539062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376177PMC
July 2012

Pharmacogenetic association of the galanin receptor (GALR1) SNP rs2717162 with smoking cessation.

Authors:
Allison B Gold E Paul Wileyto Adriana Lori David Conti Joseph F Cubells Caryn Lerman

Neuropsychopharmacology 2012 Jun 29;37(7):1683-8. Epub 2012 Feb 29.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/npp.2012.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358736PMC
June 2012

Narrative Health Communication and Behavior Change: The Influence of Exemplars in the News on Intention to Quit Smoking.

Authors:
Hyun Suk Kim Cabral A Bigman Amy E Leader Caryn Lerman Joseph N Cappella

J Commun 2012 Jun 25;62(3):473-492. Epub 2012 Apr 25.

Annenberg School for Communication, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1111/j.1460-2466.2012.01644.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377164PMC
June 2012

Extended duration therapy with transdermal nicotine may attenuate weight gain following smoking cessation.

Authors:
Robert A Schnoll E Paul Wileyto Caryn Lerman

Addict Behav 2012 Apr 26;37(4):565-8. Epub 2011 Dec 26.

Department of Psychiatry, Abramson Cancer Center, and Annenberg Public Policy Center, University of Pennsylvania, Philadelphia, PA 19104, United States.

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http://dx.doi.org/10.1016/j.addbeh.2011.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288882PMC
April 2012

Nicotine normalizes event related potentials in COMT-Val-tg mice and increases gamma and theta spectral density.

Authors:
Yufei A Cao Robert E Featherstone Michael J Gandal Yuling Liang Catherine Jutzeler John Saunders Valerie Tatard-Leitman Jingshan Chen Daniel R Weinberger Caryn Lerman Steven J Siegel

Behav Neurosci 2012 Apr 6;126(2):332-43. Epub 2012 Feb 6.

ranslational Neuroscience Program, Department of Psychiatry, University of Pennsylvania, PA, USA.

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http://dx.doi.org/10.1037/a0027047DOI Listing
April 2012

Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials.

Authors:
David P King Sara Paciga Eve Pickering Neal L Benowitz Laura J Bierut David V Conti Jaakko Kaprio Caryn Lerman Peter W Park

Neuropsychopharmacology 2012 Feb 2;37(3):641-50. Epub 2011 Nov 2.

Pfizer Global Research and Development, Groton, CT 06340, USA.

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http://dx.doi.org/10.1038/npp.2011.232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260990PMC
February 2012

Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.

Authors:
Allison B Gold Caryn Lerman

Hum Genet 2012 Jan 31. Epub 2012 Jan 31.

Center for Interdisciplinary Research on Nicotine Addiction, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA, 19104, USA.

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http://link.springer.com/10.1007/s00439-012-1143-9
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http://dx.doi.org/10.1007/s00439-012-1143-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864572PMC
January 2012

A novel recruitment message to increase enrollment into a smoking cessation treatment program: preliminary results from a randomized trial.

Authors:
Robert A Schnoll Joseph Cappella Caryn Lerman Angela Pinto Freda Patterson E Paul Wileyto Cabral Bigman Frank Leone

Health Commun 2011 Dec 11;26(8):735-42. Epub 2011 Jun 11.

Department of Psychiatry, University of Pennsylvania, Philadelphia, 19104, USA.

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http://dx.doi.org/10.1080/10410236.2011.566829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243839PMC
December 2011

The dynamics of the urge-to-smoke following smoking cessation via pharmacotherapy.

Authors:
Harold S Javitz Gary E Swan Caryn Lerman

Addiction 2011 Oct 18;106(10):1835-45. Epub 2011 Aug 18.

SRI International, Menlo Park, CA 94025, USA.

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http://dx.doi.org/10.1111/j.1360-0443.2011.03495.xDOI Listing
October 2011

Facilitating clinical implementation of pharmacogenomics.

Authors:
David A Mrazek Caryn Lerman

JAMA 2011 Jul;306(3):304-5

Department of Psychiatry, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1001/jama.2011.1010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189505PMC
July 2011

Association of the nicotine metabolite ratio and CHRNA5/CHRNA3 polymorphisms with smoking rate among treatment-seeking smokers.

Authors:
Mary Falcone Christopher Jepson Neal Benowitz Andrew W Bergen Angela Pinto E Paul Wileyto Don Baldwin Rachel F Tyndale Caryn Lerman Riju Ray

Nicotine Tob Res 2011 Jun 8;13(6):498-503. Epub 2011 Mar 8.

Department of Pharmacology, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1093/ntr/ntr012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103715PMC
June 2011

Human Mu Opioid Receptor (OPRM1 A118G) polymorphism is associated with brain mu-opioid receptor binding potential in smokers.

Authors:
Riju Ray Kosha Ruparel Andrew Newberg E Paul Wileyto James W Loughead Chaitanya Divgi Julie A Blendy Jean Logan Jon-Kar Zubieta Caryn Lerman

Proc Natl Acad Sci U S A 2011 May 16;108(22):9268-73. Epub 2011 May 16.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1073/pnas.1018699108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107291PMC
May 2011

Smoking cues, argument strength, and perceived effectiveness of antismoking PSAs.

Authors:
Sungkyoung Lee Joseph N Cappella Caryn Lerman Andrew A Strasser

Nicotine Tob Res 2011 Apr 24;13(4):282-90. Epub 2011 Jan 24.

Center of Excellence in Cancer Communication Research, Annenberg School of Communication, University of Pennsylvania, 3620 Walnut St., Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/ntr/ntq255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066405PMC
April 2011

A Measure of Perceived Argument Strength: Reliability and Validity.

Authors:
Xiaoquan Zhao Andrew Strasser Joseph N Cappella Caryn Lerman Martin Fishbein

Commun Methods Meas 2011 Mar;5(1):48-75

University of Pennsylvania.

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http://dx.doi.org/10.1080/19312458.2010.547822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283835PMC
March 2011

Nicotine metabolite ratio predicts smoking topography and carcinogen biomarker level.

Authors:
Andrew A Strasser Neal L Benowitz Angela G Pinto Kathy Z Tang Stephen S Hecht Steve G Carmella Rachel F Tyndale Caryn E Lerman

Cancer Epidemiol Biomarkers Prev 2011 Feb 6;20(2):234-8. Epub 2011 Jan 6.

Department of Psychiatry and Abramson Cancer Center, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104-3309, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-10-0674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077576PMC
February 2011

A new chapter in the history of SRNT: the formation of the European chapter of SRNT (SRNT-E)--a letter from the Presidents of SRNT and SRNT Europe.

Authors:
Christian Chiamulera Caryn Lerman Sakire Pogun

Nicotine Tob Res 2010 Dec 8;12(12):1181-2. Epub 2010 Nov 8.

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http://dx.doi.org/10.1093/ntr/ntq180DOI Listing
December 2010

Preclinical data elucidate molecular and neural mechanisms of perinatal nicotine effects on neurodevelopment and behavior: translational opportunities and implications.

Authors:
Caryn Lerman

Neuropsychopharmacology 2010 Nov;35(12):2322-3

Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/npp.2010.147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055325PMC
November 2010

Replication and extension of association of choline acetyltransferase with nicotine dependence in European and African American smokers.

Authors:
Jinxue Wei Jennie Z Ma Thomas J Payne Wenyan Cui Riju Ray Nandita Mitra Caryn Lerman Ming D Li

Hum Genet 2010 Jun 10;127(6):691-8. Epub 2010 Apr 10.

Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, 1670 Discovery Drive, Suite 110, Charlottesville, VA 22911, USA.

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http://dx.doi.org/10.1007/s00439-010-0818-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574174PMC
June 2010

Mouse model predicts effects of smoking and varenicline on event-related potentials in humans.

Authors:
Noam D Rudnick Andrew A Strasser Jennifer M Phillips Christopher Jepson Freda Patterson Joseph M Frey Bruce I Turetsky Caryn Lerman Steven J Siegel

Nicotine Tob Res 2010 Jun 15;12(6):589-97. Epub 2010 Apr 15.

Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/ntr/ntq049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878727PMC
June 2010

Convergent evidence that choline acetyltransferase gene variation is associated with prospective smoking cessation and nicotine dependence.

Authors:
Riju Ray Nandita Mitra Don Baldwin Mengye Guo Freda Patterson Daniel F Heitjan Christopher Jepson E Paul Wileyto Jinxue Wei Thomas Payne Jennie Z Ma Ming D Li Caryn Lerman

Neuropsychopharmacology 2010 May 10;35(6):1374-82. Epub 2010 Feb 10.

Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/npp.2010.7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855736PMC
May 2010

Varenicline's effects on acute smoking behavior and reward and their association with subsequent abstinence.

Authors:
Kenneth A Perkins Melissa Mercincavage Carolyn A Fonte Caryn Lerman

Psychopharmacology (Berl) 2010 May 20;210(1):45-51. Epub 2010 Mar 20.

Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1007/s00213-010-1816-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863002PMC
May 2010

Nicotine vaccines: will smokers take a shot at quitting?

Authors:
Amy E Leader Caryn Lerman Joseph N Cappella

Nicotine Tob Res 2010 Apr 25;12(4):390-7. Epub 2010 Feb 25.

Center of Excellence in Cancer Communication Research, Annenberg School for Communication, University of Pennsylvania, 3620 Walnut Street, 410, Philadelphia, PA 19104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847077PMC
April 2010

Effects of the alpha4beta2 partial agonist varenicline on brain activity and working memory in abstinent smokers.

Authors:
James Loughead Riju Ray E Paul Wileyto Kosha Ruparel Paul Sanborn Steven Siegel Ruben C Gur Caryn Lerman

Biol Psychiatry 2010 Apr 6;67(8):715-21. Epub 2010 Mar 6.

Brain Behavior Laboratory, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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April 2010

Reinforcing effects of smoking: more than a feeling.

Authors:
Caryn Lerman Janet Audrain-McGovern

Biol Psychiatry 2010 Apr;67(8):699-701

Transdisciplinary Tobacco Use Research Center, Department of Psychiatry and Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1016/j.biopsych.2010.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857778PMC
April 2010

The public health utility of genome-wide association study results for smoking behavior.

Authors:
Helena Furberg Jamie Ostroff Caryn Lerman Patrick F Sullivan

Genome Med 2010 Apr 27;2(4):26. Epub 2010 Apr 27.

Department of Psychiatry and Behavioral Science, Memorial Sloan Kettering Cancer Center, 641 Lexington Ave, New York, NY 10022, USA.

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http://genomemedicine.biomedcentral.com/articles/10.1186/gm1
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873804PMC
April 2010

Translational medication development for nicotine addiction.

Authors:
Glen Morgan Cathy Backinger Caryn Lerman Francis Vocci

Am J Health Behav 2010 May-Jun;34(3):267-74

Tobacco Control Research Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20852, USA.

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http://dx.doi.org/10.5993/ajhb.34.3.2DOI Listing
February 2010

Effectiveness of extended-duration transdermal nicotine therapy: a randomized trial.

Authors:
Robert A Schnoll Freda Patterson E Paul Wileyto Daniel F Heitjan Alexandra E Shields David A Asch Caryn Lerman

Ann Intern Med 2010 Feb;152(3):144-51

Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.7326/0003-4819-152-3-201002020-00005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782858PMC
February 2010

Working memory deficits predict short-term smoking resumption following brief abstinence.

Authors:
Freda Patterson Christopher Jepson James Loughead Kenneth Perkins Andrew A Strasser Steven Siegel Joseph Frey Ruben Gur Caryn Lerman

Drug Alcohol Depend 2010 Jan 5;106(1):61-4. Epub 2009 Sep 5.

Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2009.07.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815089PMC
January 2010

Transdisciplinary Tobacco Use Research Centers: research achievements and future implications.

Authors:
Timothy B Baker K Michael Cummings Dorothy K Hatsukami C Anderson Johnson Caryn Lerman Raymond Niaura Stephanie S O'Malley

Nicotine Tob Res 2009 Oct 24;11(10):1231-44. Epub 2009 Jul 24.

Center for Tobacco and Intervention, Department of Medicine, 1930 Monroe Street, Suite 200, Madison, WI 53711, USA.

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http://dx.doi.org/10.1093/ntr/ntp112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746833PMC
October 2009

Nicotinic acetylcholine receptor beta2 subunit (CHRNB2) gene and short-term ability to quit smoking in response to nicotine patch.

Authors:
Kenneth A Perkins Caryn Lerman Melissa Mercincavage Carolyn A Fonte Jessica L Briski

Cancer Epidemiol Biomarkers Prev 2009 Oct 15;18(10):2608-12. Epub 2009 Sep 15.

Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-09-0166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759850PMC
October 2009

Nicotine dependence: biology, behavior, and treatment.

Authors:
Riju Ray Robert A Schnoll Caryn Lerman

Annu Rev Med 2009 ;60:247-60

Transdisciplinary Tobacco Use Research Center, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1146/annurev.med.60.041707.160511DOI Listing
September 2009

Behavioral oncology and the war on cancer: partnering with biomedicine.

Authors:
Michael E Stefanek Michael A Andrykowski Caryn Lerman Sharon Manne Karen Glanz

Cancer Res 2009 Sep 25;69(18):7151-6. Epub 2009 Aug 25.

Behavioral Research Center, American Cancer Society, 250 Williams Street, Northwest, Atlanta, GA 30303, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-4005DOI Listing
September 2009

A systems biology network model for genetic association studies of nicotine addiction and treatment.

Authors:
Paul D Thomas Huaiyu Mi Gary E Swan Caryn Lerman Neal Benowitz Rachel F Tyndale Andrew W Bergen David V Conti

Pharmacogenet Genomics 2009 Jul;19(7):538-51

Evolutionary Systems Biology, Artificial Intelligence Center, SRI International, Menlo Park, CA 94025, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32832e2cedDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485245PMC
July 2009

Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior.

Authors:
Stephen D Mague Carolina Isiegas Peng Huang Lee-Yuan Liu-Chen Caryn Lerman Julie A Blendy

Proc Natl Acad Sci U S A 2009 Jun 15;106(26):10847-52. Epub 2009 Jun 15.

Department of Pharmacology, Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0901800106
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June 2009