Carsten Janke

Carsten Janke

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Carsten Janke

Publications by authors named "Carsten Janke"

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Microtubule-Associated Proteins: Structuring the Cytoskeleton.

Trends Cell Biol 2019 Oct 12;29(10):804-819. Epub 2019 Aug 12.

Institut Curie, Paris Sciences et Lettres (PSL) Research University, Centre National de la Recherche Scientifique (CNRS) Unité Mixte de Recherche (UMR) 3348, F-91405 Orsay, France; Université Paris Sud, Université Paris-Saclay, CNRS UMR 3348, F-91405 Orsay, France. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2019.07.004DOI Listing
October 2019

Purification of tubulin with controlled post-translational modifications by polymerization-depolymerization cycles.

Nat Protoc 2019 05 17;14(5):1634-1660. Epub 2019 Apr 17.

Institut Curie, PSL Research University, CNRS UMR 3348, Orsay, France.

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http://dx.doi.org/10.1038/s41596-019-0153-7DOI Listing
May 2019

An essential role for α4A-tubulin in platelet biogenesis.

Life Sci Alliance 2019 02 13;2(1). Epub 2019 Feb 13.

Université de Strasbourg, Institut National de la Santé et de la Recherche Médicale, Etablissement Français du Sang Grand Est, Unité Mixte de Recherche-S 1255, Fédération de Médecine Translationnelle de Strasbourg, Strasbourg, France

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http://dx.doi.org/10.26508/lsa.201900309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374996PMC
February 2019

Kinesin-3 Responds to Local Microtubule Dynamics to Target Synaptic Cargo Delivery to the Presynapse.

Curr Biol 2019 Jan 3;29(2):268-282.e8. Epub 2019 Jan 3.

Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6085, USA; The Pennsylvania Muscle Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6085, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2018.11.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342647PMC
January 2019

Tubulin Posttranslational Modifications and Emerging Links to Human Disease.

Cell 2018 05 31;173(6):1323-1327. Epub 2018 May 31.

Institut Curie, PSL Research University, CNRS UMR3348, Orsay, France; Université Paris Sud, Université Paris-Saclay, CNRS UMR3348, Orsay, France. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.05.018DOI Listing
May 2018

SnapShot: Functions of Tubulin Posttranslational Modifications.

Cell 2018 05 31;173(6):1552-1552.e1. Epub 2018 May 31.

Institut Curie, 91405 Orsay, France.

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http://dx.doi.org/10.1016/j.cell.2018.05.032DOI Listing
May 2018

The comeback of hand drawing in modern life sciences.

Nat Rev Mol Cell Biol 2018 03 20;19(3):137-138. Epub 2017 Dec 20.

Institut Curie, PSL Research University, CNRS UMR3348, F-91405 Orsay, France.

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http://dx.doi.org/10.1038/nrm.2017.126DOI Listing
March 2018

A unified reviewing format for grant applications and evaluations.

Authors:
Carsten Janke

EMBO Rep 2018 02 27;19(2):187-188. Epub 2017 Dec 27.

Institut Curie, PSL Research University, CNRS UMR3348, Orsay, France.

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http://dx.doi.org/10.15252/embr.201745611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797963PMC
February 2018

Cytoskeleton stability is essential for the integrity of the cerebellum and its motor- and affective-related behaviors.

Sci Rep 2018 02 15;8(1):3072. Epub 2018 Feb 15.

Laboratory of Neural Plasticity and Neurorepair. Institute for Neurosciences of Castile and Leon (INCyL), University of Salamanca, E-37007, Salamanca, Spain.

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http://dx.doi.org/10.1038/s41598-018-21470-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814431PMC
February 2018

Causes and Consequences of Microtubule Acetylation.

Curr Biol 2017 Dec;27(23):R1287-R1292

Inserm U1170, Gustave Roussy Institute, Université Paris-Saclay, F-94800 Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2017.10.044DOI Listing
December 2017

Spindle asymmetry drives non-Mendelian chromosome segregation.

Science 2017 11;358(6363):668-672

Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/science.aan0092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906099PMC
November 2017

Tubulin glycylation controls primary cilia length.

J Cell Biol 2017 09 7;216(9):2701-2713. Epub 2017 Jul 7.

Institut Curie, Paris Sciences et Lettres Research University, Centre National de la Recherche Scientifique UMR3348, Orsay, France

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http://dx.doi.org/10.1083/jcb.201612050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584158PMC
September 2017

The tubulin code at a glance.

J Cell Sci 2017 04 21;130(8):1347-1353. Epub 2017 Mar 21.

Institut Curie, PSL Research University, CNRS UMR3348, Orsay F-91405, France

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http://dx.doi.org/10.1242/jcs.199471DOI Listing
April 2017

Alterations in the balance of tubulin glycylation and glutamylation in photoreceptors leads to retinal degeneration.

J Cell Sci 2017 03 19;130(5):938-949. Epub 2017 Jan 19.

Institut Curie, PSL Research University, CNRS UMR3348, Orsay F-91405, France

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http://dx.doi.org/10.1242/jcs.199091DOI Listing
March 2017

The emerging role of the tubulin code: From the tubulin molecule to neuronal function and disease.

Cytoskeleton (Hoboken) 2016 Oct 9;73(10):521-550. Epub 2016 May 9.

Children's National Health System, Center for Neuroscience Research, Washington, District of Columbia.

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http://dx.doi.org/10.1002/cm.21290DOI Listing
October 2016

Microtubules: 50 years on from the discovery of tubulin.

Nat Rev Mol Cell Biol 2016 04;17(5):322-8

Biochemistry, Biophysics and Structural Biology Division, Molecular and Cell Biology Department, University of California, Berkeley, California 94720-3220, USA; the Howard Hughes Medical Institute, Maryland, USA; and the Lawrence Berkeley National Laboratory, USA.

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http://dx.doi.org/10.1038/nrm.2016.45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116387PMC
April 2016

α-Tubulin Tyrosination and CLIP-170 Phosphorylation Regulate the Initiation of Dynein-Driven Transport in Neurons.

Cell Rep 2016 Mar 10;14(11):2637-52. Epub 2016 Mar 10.

Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.02.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819336PMC
March 2016

Evidence for new C-terminally truncated variants of α- and β-tubulins.

Mol Biol Cell 2016 Feb 6;27(4):640-53. Epub 2016 Jan 6.

Université Grenoble Alpes, Grenoble Institut des Neurosciences, GIN, F-38000 Grenoble, France Inserm, U1216, F-38000 Grenoble, France

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http://dx.doi.org/10.1091/mbc.E15-03-0137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750924PMC
February 2016

Ependymal cell differentiation, from monociliated to multiciliated cells.

Methods Cell Biol 2015 7;127:19-35. Epub 2015 Mar 7.

Institut de Biologie de l'Ecole Normal Supérieure (IBENS), Paris, France; INSERM, U1024, Paris, France; CNRS, UMR 8197, Paris, France.

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http://dx.doi.org/10.1016/bs.mcb.2015.01.004DOI Listing
January 2016

Optochemistry to control the microtubule cytoskeleton.

EMBO J 2015 Aug 17;34(16):2114-6. Epub 2015 Jul 17.

Laboratory of Biomolecular Research, Department of Biology and Chemistry, Paul Scherrer Institut, Villigen PSI, Switzerland.

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http://dx.doi.org/10.15252/embj.201592415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557664PMC
August 2015

Mitosis. Microtubule detyrosination guides chromosomes during mitosis.

Science 2015 May 23;348(6236):799-803. Epub 2015 Apr 23.

Chromosome Instability and Dynamics Laboratory, Instituto de Biologia Molecular e Celular, Universidade do Porto, Rua do Campo Alegre 823, 4150-180 Porto, Portugal. Instituto de Investigação e Inovação em Saúde-i3S, Universidade do Porto, Portugal. Cell Division Unit, Department of Experimental Biology, Faculdade de Medicina, Universidade do Porto, Alameda Professor Hernâni Monteiro, 4200-319 Porto, Portugal.

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http://dx.doi.org/10.1126/science.aaa5175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506776PMC
May 2015

Characterisation of polyglutamylases in trypanosomatids.

Int J Parasitol 2015 Feb 13;45(2-3):121-32. Epub 2014 Nov 13.

Centre National de la Recherche Scientifique (CNRS), 5290-IRD 224-University Montpellier 1, Research Unit "MIVEGEC", Montpellier, France; CHU (Hospital University Centre) of Montpellier and University Montpellier 1 (Faculty of Medicine), Laboratoire de Parasitologie-Mycologie, Montpellier, France. Electronic address:

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http://dx.doi.org/10.1016/j.ijpara.2014.09.005DOI Listing
February 2015

The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids.

Mol Biol Cell 2014 Oct 7;25(19):3017-27. Epub 2014 Aug 7.

Institut Curie, 91405 Orsay, France PSL Research University, 75005 Paris, France Centre National de la Recherche Scientifique, UMR3306, 91405 Orsay, France Institut National de la Santé et de la Recherche Médicale, U1005, 91405 Orsay, France

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http://dx.doi.org/10.1091/mbc.E14-06-1072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230590PMC
October 2014

The tubulin code: molecular components, readout mechanisms, and functions.

Authors:
Carsten Janke

J Cell Biol 2014 Aug;206(4):461-72

Institut Curie, 91405 Orsay, France Centre National de la Recherche Scientifique Unité Mixte de Recherche 3306, 91405 Orsay, France Institut National de la Santé et de la Recherche Médicale U1005, 91405 Orsay, France Paris Sciences et Lettres Research University, 75005 Paris, France

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http://dx.doi.org/10.1083/jcb.201406055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137062PMC
August 2014

Post-translational modifications of tubulin.

Curr Biol 2014 May;24(9):R351-4

Institut Curie, CNRS UMR3306, INSERM U1005, Centre Universitaire, Bâtiment 110, 91405 Orsay, France. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2014.03.032DOI Listing
May 2014

Investigating tubulin posttranslational modifications with specific antibodies.

Methods Cell Biol 2013 ;115:247-67

Institut Curie, CNRS UMR3306, INSERM U1005, Orsay, France.

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http://dx.doi.org/10.1016/B978-0-12-407757-7.00016-5DOI Listing
April 2014

Towards elucidating the tubulin code.

Nat Cell Biol 2014 Apr;16(4):303-5

Institut Curie, Department of Signalling, Neurobiology and Cancer, CNRS UMR 3306/INSERM U1005, Bat 110, Centre Universitaire, 91405 Orsay Cedex, France.

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http://dx.doi.org/10.1038/ncb2938DOI Listing
April 2014

Bug22 influences cilium morphology and the post-translational modification of ciliary microtubules.

Biol Open 2014 Feb 15;3(2):138-51. Epub 2014 Feb 15.

Institut Curie, CNRS UMR144, 12 rue Lhomond, 75005 Paris, France.

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http://dx.doi.org/10.1242/bio.20146577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925317PMC
February 2014

Generation of differentially polyglutamylated microtubules.

Methods Mol Biol 2011 ;777:57-69

CRBM, Université Montpellier 2 and 1, CNRS, Montpellier, France.

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http://dx.doi.org/10.1007/978-1-61779-252-6_4DOI Listing
November 2011

Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions.

Nat Rev Mol Cell Biol 2011 Nov 16;12(12):773-86. Epub 2011 Nov 16.

Department of Signalling, Neurobiology and Cancer, Institut Curie, Bât. 110, Centre Universitaire, 91405 Orsay Cedex, France.

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http://dx.doi.org/10.1038/nrm3227DOI Listing
November 2011

Tubulin post-translational modifications: encoding functions on the neuronal microtubule cytoskeleton.

Trends Neurosci 2010 Aug 11;33(8):362-72. Epub 2010 Jun 11.

Institut Curie, Bâtiment 110, Centre Universitaire, F-91405 Orsay Cedex, France.

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http://dx.doi.org/10.1016/j.tins.2010.05.001DOI Listing
August 2010

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing.

J Cell Biol 2010 Jun 7;189(6):945-54. Epub 2010 Jun 7.

Centre de Recherche de Biochimie Macromoléculaire, Université Montpellier 2 and 1, Centre National de la Recherche Scientifique UMR 5237, Montpellier, France.

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http://dx.doi.org/10.1083/jcb.201001024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886356PMC
June 2010

Synaptic activation modifies microtubules underlying transport of postsynaptic cargo.

Proc Natl Acad Sci U S A 2009 May 13;106(21):8731-6. Epub 2009 May 13.

Zentrum für Molekulare Neurobiologie Hamburg, Universität Hamburg, Hamburg, Germany.

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http://dx.doi.org/10.1073/pnas.0812391106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681317PMC
May 2009

CLIP-170 tracks growing microtubule ends by dynamically recognizing composite EB1/tubulin-binding sites.

J Cell Biol 2008 Dec 22;183(7):1223-33. Epub 2008 Dec 22.

European Molecular Biology Laboratory, Cell Biology and Biophysics Unit, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1083/jcb.200809190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606963PMC
December 2008

Polyglutamylation: a fine-regulator of protein function? 'Protein Modifications: beyond the usual suspects' review series.

EMBO Rep 2008 Jul 20;9(7):636-41. Epub 2008 Jun 20.

Centre de Recherches de Biochimie Macromoléculaire, Centre National de la Recherche Scientifique, University Montpellier 2 and 1, 1919 Route de Mende, 34293 Montpellier, France.

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http://dx.doi.org/10.1038/embor.2008.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475320PMC
July 2008

Polyglutamylation is a post-translational modification with a broad range of substrates.

J Biol Chem 2008 Feb 28;283(7):3915-22. Epub 2007 Nov 28.

Centre de Recherche de Biochimie Macromoléculaire, Universités Montpellier 2 and 1, CNRS, 34293 Montpellier, France.

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http://dx.doi.org/10.1074/jbc.M705813200DOI Listing
February 2008

Nsl1p is essential for the establishment of bipolarity and the localization of the Dam-Duo complex.

EMBO J 2003 Dec;22(24):6584-97

Biochemie-Zentrum Heidelberg Ruprecht-Karls Universität, Im Neuenheimer Feld 328, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/emboj/cdg636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC291831PMC
December 2003

Characterisation of PGs1, a subunit of a protein complex co-purifying with tubulin polyglutamylase.

J Cell Sci 2003 Oct;116(Pt 20):4181-90

Centre de Recherches de Biochimie Macromoléculaire, CNRS, 34293 Montpellier, France.

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http://dx.doi.org/10.1242/jcs.00743DOI Listing
October 2003

Drosophila DSP1 and rat HMGB1 have equivalent DNA binding properties and share a similar secondary fold.

J Biochem 2003 Apr;133(4):533-9

Centre de Biophysique Moléculaire, CNRS, conventionné avec l'Université d'Orléans, rue Charles Sadron, 45071 Orléans cedex 2, France.

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http://dx.doi.org/10.1093/jb/mvg063DOI Listing
April 2003

Four new subunits of the Dam1-Duo1 complex reveal novel functions in sister kinetochore biorientation.

EMBO J 2002 Jan;21(1-2):181-93

The Beatson Institute for Cancer Research, CRC Beatson Laboratories, Glasgow G61 1BD, UK.

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http://dx.doi.org/10.1093/emboj/21.1.181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC125813PMC
January 2002