Publications by authors named "Carsten C Scholz"

28Publications

Inhibition of firefly luciferase activity by a HIF prolyl hydroxylase inhibitor.

J Photochem Photobiol B 2020 Sep 27;210:111980. Epub 2020 Jul 27.

Institute of Physiology, University of Zurich, Zurich, & National Centre of Competence in Research 'Kidney.CH', Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jphotobiol.2020.111980DOI Listing
September 2020

HIF hydroxylase inhibitors decrease cellular oxygen consumption depending on their selectivity.

FASEB J 2020 02 19;34(2):2344-2358. Epub 2019 Dec 19.

Institute of Physiology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1096/fj.201902240RDOI Listing
February 2020

Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1.

Redox Biol 2019 09 2;26:101265. Epub 2019 Jul 2.

Institute of Physiology, University of Zurich, 8057, Zurich, Switzerland; National Centre of Competence in Research 'Kidney.CH', Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624438PMC
September 2019

Genetic Knockdown and Pharmacologic Inhibition of Hypoxia-Inducible Factor (HIF) Hydroxylases.

Methods Mol Biol 2018 ;1742:1-14

Institute of Physiology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1007/978-1-4939-7665-2_1DOI Listing
August 2018

The functional interplay between the HIF pathway and the ubiquitin system - more than a one-way road.

Exp Cell Res 2017 07 15;356(2):152-159. Epub 2017 Mar 15.

Institute of Physiology, University of Zurich, 8057 Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2017.03.027DOI Listing
July 2017

Intermittent hypoxia confers pro-metastatic gene expression selectively through NF-κB in inflammatory breast cancer cells.

Free Radic Biol Med 2016 12 5;101:129-142. Epub 2016 Oct 5.

Institute of Physiology, University of Zurich, 8057 Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.10.002DOI Listing
December 2016

Hypoxia: from basic mechanisms to therapeutics - a meeting report on the Keystone and HypoxiaNet Symposium.

Hypoxia (Auckl) 2015 23;3:67-72. Epub 2015 Oct 23.

Institute of Physiology, University of Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.2147/HP.S83240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045090PMC
October 2015

Frequently asked questions in hypoxia research.

Hypoxia (Auckl) 2015 18;3:35-43. Epub 2015 Sep 18.

Institute of Physiology and Zurich Center for Human Physiology (ZIHP), University of Zurich; National Center of Competence in Research "Kidney. CH", Zurich, Switzerland; Institute of Physiology, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.2147/HP.S92198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045069PMC
September 2015

Hypercapnia Suppresses the HIF-dependent Adaptive Response to Hypoxia.

J Biol Chem 2016 May 4;291(22):11800-8. Epub 2016 Apr 4.

From the School of Medicine and Medical Science, Conway Institute, and Systems Biology Ireland, University College Dublin, Belfield, Dublin 4, Ireland,

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http://dx.doi.org/10.1074/jbc.M116.713941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882447PMC
May 2016

Editorial: a PHD in macrophage survival.

J Leukoc Biol 2014 Sep;96(3):359-61

Systems Biology Ireland, School of Medicine and Medical Science and The Conway Institute, University College Dublin, Belfield, Dublin, Ireland.

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http://dx.doi.org/10.1189/jlb.3CE0314-157RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395932PMC
September 2014

Paricalcitol protects against TGF-β1-induced fibrotic responses in hypoxia and stabilises HIF-α in renal epithelia.

Exp Cell Res 2015 Jan 5;330(2):371-381. Epub 2014 Aug 5.

Diabetes Complications Research Centre, Conway Institute of Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Belfield, Dublin 4, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2014.07.034DOI Listing
January 2015

Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.

Proc Natl Acad Sci U S A 2013 Nov 21;110(46):18490-5. Epub 2013 Oct 21.

Systems Biology Ireland, School of Medicine and Medical Science, and Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1073/pnas.1309718110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832034PMC
November 2013

Targeting the HIF pathway in inflammation and immunity.

Curr Opin Pharmacol 2013 Aug 7;13(4):646-53. Epub 2013 May 7.

Systems Biology Ireland, School of Medicine and Medical Science & The Conway Institute, University College Dublin, Ireland.

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http://dx.doi.org/10.1016/j.coph.2013.04.009DOI Listing
August 2013

A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.

J Cell Sci 2013 Mar 6;126(Pt 6):1454-63. Epub 2013 Feb 6.

Systems Biology Ireland, University College Dublin, Dublin 4, Ireland.

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http://dx.doi.org/10.1242/jcs.119974DOI Listing
March 2013

Hydroxylase-dependent regulation of the NF-κB pathway.

Biol Chem 2013 Apr;394(4):479-93

School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1515/hsz-2012-0338DOI Listing
April 2013

MicroRNA-155 promotes resolution of hypoxia-inducible factor 1alpha activity during prolonged hypoxia.

Mol Cell Biol 2011 Oct 1;31(19):4087-96. Epub 2011 Aug 1.

School of Medicine and Medical Science and UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1128/MCB.01276-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187364PMC
October 2011

Small ubiquitin-related modifier (SUMO)-1 promotes glycolysis in hypoxia.

J Biol Chem 2011 Feb 1;286(6):4718-26. Epub 2010 Dec 1.

UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1074/jbc.M110.115931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039330PMC
February 2011

NF-κB links CO2 sensing to innate immunity and inflammation in mammalian cells.

J Immunol 2010 Oct 3;185(7):4439-45. Epub 2010 Sep 3.

UCD Conway Institute for Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland.

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http://dx.doi.org/10.4049/jimmunol.1000701DOI Listing
October 2010