Publications by authors named "Carolyn Worby"

35Publications

The 5th International Lafora Epilepsy Workshop: Basic science elucidating therapeutic options and preparing for therapies in the clinic.

Epilepsy Behav 2020 02 10;103(Pt A):106839. Epub 2020 Jan 10.

Lafora Epilepsy Cure Initiative (LECI), USA; Laboratory of Neurology, IIS-Jimenez Diaz Foundation, UAM, 28045 Madrid, Spain; Biomedical Research Networking Center on Rare Diseases (CIBERER), 28029 Madrid, Spain.

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http://dx.doi.org/10.1016/j.yebeh.2019.106839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024738PMC
February 2020

Reversible phosphorylation: a birthday tribute to Herb Tabor.

J Biol Chem 2019 02;294(5):1638-1642

From the Departments of Pharmacology.

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http://dx.doi.org/10.1074/jbc.TME118.004161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364790PMC
February 2019

Unpacking the unfolded protein response.

Cell 2014 Sep;158(6):1221-1224

Departments of Pharmacology, Cellular and Molecular Medicine, and Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.08.025DOI Listing
September 2014

PTEN.

Annu Rev Biochem 2014 ;83:641-69

Department of Pharmacology, University of California, San Diego, La Jolla, California 92093-0721; email:

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http://dx.doi.org/10.1146/annurev-biochem-082411-113907DOI Listing
January 2015

A malachite green-based assay to assess glucan phosphatase activity.

Anal Biochem 2013 Apr 29;435(1):54-6. Epub 2012 Nov 29.

Department of Molecular and Cellular Biochemistry, Center for Structural Biology, University of Kentucky, Lexington, KY 40536, USA.

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http://dx.doi.org/10.1016/j.ab.2012.10.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577954PMC
April 2013

Secreted kinase phosphorylates extracellular proteins that regulate biomineralization.

Science 2012 Jun 10;336(6085):1150-3. Epub 2012 May 10.

Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093-0721, USA.

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http://dx.doi.org/10.1126/science.1217817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754843PMC
June 2012

Antibody responses of calves to Histophilus somni recombinant IbpA subunits.

Comp Immunol Microbiol Infect Dis 2012 Sep 2;35(5):453-9. Epub 2012 May 2.

Department of Pathology, University of California, San Diego, San Diego, CA 92103, USA.

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http://dx.doi.org/10.1016/j.cimid.2012.04.002DOI Listing
September 2012

Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity.

Hum Mol Genet 2012 Apr 20;21(7):1604-10. Epub 2011 Dec 20.

Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1093/hmg/ddr598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298283PMC
April 2012

Comparative analysis of Histophilus somni immunoglobulin-binding protein A (IbpA) with other fic domain-containing enzymes reveals differences in substrate and nucleotide specificities.

J Biol Chem 2011 Sep 27;286(37):32834-42. Epub 2011 Jul 27.

Department of Pharmacology, Howard Hughes Medical Institute, University of California, San Diego, La Jolla, California 92093-0721, USA.

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http://dx.doi.org/10.1074/jbc.M111.227603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173180PMC
September 2011

Glycogen synthase: an old enzyme with a new trick.

Cell Metab 2011 Mar;13(3):233-4

Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1016/j.cmet.2011.02.006DOI Listing
March 2011

Structural basis of Fic-mediated adenylylation.

Nat Struct Mol Biol 2010 Aug 11;17(8):1004-10. Epub 2010 Jul 11.

Department of Pharmacology, Howard Hughes Medical Institute, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1038/nsmb.1867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920259PMC
August 2010

Histophilus somni IbpA DR2/Fic in virulence and immunoprotection at the natural host alveolar epithelial barrier.

Infect Immun 2010 May 22;78(5):1850-8. Epub 2010 Feb 22.

Department of Pathology, University of California San Diego, 200 W. Arbor Drive, San Diego, CA 92103-8416, USA.

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http://dx.doi.org/10.1128/IAI.01277-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863524PMC
May 2010

Lafora disease: insights into neurodegeneration from plant metabolism.

Trends Biochem Sci 2009 Dec 7;34(12):628-39. Epub 2009 Oct 7.

Department of Molecular and Cellular Biochemistry and Center for Structural Biology, University of Kentucky, Lexington, KY 40536-0509, USA.

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http://dx.doi.org/10.1016/j.tibs.2009.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805077PMC
December 2009

A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate.

Proc Natl Acad Sci U S A 2008 Jun 4;105(23):7970-5. Epub 2008 Jun 4.

Section for Developmental Neurophysiology, Okazaki Center for Integrative Biosciences, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 4448787, Japan.

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http://dx.doi.org/10.1073/pnas.0803936105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430346PMC
June 2008

RNA interference in cultured Drosophila cells.

Curr Protoc Mol Biol 2004 Feb;Chapter 26:Unit 26.5

University of California at San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1002/0471142727.mb2605s65DOI Listing
February 2004

Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG).

J Biol Chem 2008 Feb 10;283(7):4069-76. Epub 2007 Dec 10.

Department of Pharmacology, University of California at San Diego, La Jolla, California 92093-0721, USA.

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http://dx.doi.org/10.1074/jbc.M708712200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2251628PMC
February 2008

A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease.

Genes Dev 2007 Oct;21(19):2399-409

Department of Internal Medicine, Life Sciences Institute, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1101/gad.1553207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1993871PMC
October 2007

The phosphatase laforin crosses evolutionary boundaries and links carbohydrate metabolism to neuronal disease.

J Cell Biol 2007 Jul 23;178(3):477-88. Epub 2007 Jul 23.

Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1083/jcb.200704094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064834PMC
July 2007

Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates.

J Biol Chem 2006 Oct 10;281(41):30412-8. Epub 2006 Aug 10.

Department of Pharmacology, University of California at San Diego, La Jolla, California 92093-0721, USA.

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http://dx.doi.org/10.1074/jbc.M606117200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774450PMC
October 2006

Microbiology. Bacteria seize control by acetylating host proteins.

Science 2006 May;312(5777):1150-1

Department of Pharmacology, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1126/science.1128785DOI Listing
May 2006

Phosphoinositide phosphatases: emerging roles as voltage sensors?

Mol Interv 2005 Oct;5(5):274-7

Department of Pharmacology, University of California-San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1124/mi.5.5.5DOI Listing
October 2005

Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin.

Proc Natl Acad Sci U S A 2005 Jun 1;102(24):8501-6. Epub 2005 Jun 1.

Department of Pharmacology, School of Medicine, University of California at San Diego, La Jolla, CA 92093-0721, USA.

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http://dx.doi.org/10.1073/pnas.0503285102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1150849PMC
June 2005

A PTEN-like phosphatase with a novel substrate specificity.

J Biol Chem 2004 Sep 9;279(37):38590-6. Epub 2004 Jul 9.

Department of Pharmacology, University of California, San Diego, La Jolla, California 92093-0721, USA.

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http://dx.doi.org/10.1074/jbc.M404959200DOI Listing
September 2004

Sorting out the cellular functions of sorting nexins.

Nat Rev Mol Cell Biol 2002 Dec;3(12):919-31

Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1038/nrm974DOI Listing
December 2002

Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance.

J Biol Chem 2002 Mar 28;277(11):9422-8. Epub 2001 Dec 28.

Life Sciences Institute and Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109-0606, USA.

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http://dx.doi.org/10.1074/jbc.M110172200DOI Listing
March 2002