Carolyn S P Lam

Carolyn S P Lam

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Carolyn S P Lam

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Time to rename the middle child of heart failure: heart failure with mildly reduced ejection fraction.

Eur Heart J 2020 Jul;41(25):2353-2355

Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/eurheartj/ehaa158DOI Listing
July 2020

Risk of cardiovascular events and death associated with initiation of SGLT2 inhibitors compared with DPP-4 inhibitors: an analysis from the CVD-REAL 2 multinational cohort study.

Lancet Diabetes Endocrinol 2020 Jul;8(7):606-615

George Institute for Global Health, Sydney, NSW, Australia; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA; University of Missouri-Kansas City, Kansas City, MO, USA; University of New South Wales in Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/S2213-8587(20)30130-3DOI Listing
July 2020

Left atrial strain as sensitive marker of left ventricular diastolic dysfunction in heart failure.

ESC Heart Fail 2020 Jul 2. Epub 2020 Jul 2.

Department of Internal Medicine and Cardiology, Charité University Medicine (Campus Virchow Klinikum), Augustenburger Platz 1, Berlin, 13353, Germany.

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http://dx.doi.org/10.1002/ehf2.12820DOI Listing
July 2020

Sex differences in mineralocorticoid receptor antagonist trials: a pooled analysis of three large clinical trials.

Eur J Heart Fail 2020 May 19;22(5):834-844. Epub 2020 Feb 19.

Centre d'Investigation Clinique-Plurithématique INSERM CIC-P 1433, and INSERM U1116, CHRU Nancy Brabois, F-CRIN INI-CRCT, Université de Lorraine, Nancy, France.

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http://dx.doi.org/10.1002/ejhf.1740DOI Listing
May 2020

Interactions between left ventricular ejection fraction, sex and effect of neurohumoral modulators in heart failure.

Eur J Heart Fail 2020 May 2;22(5):898-901. Epub 2020 Mar 2.

BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1002/ejhf.1776DOI Listing
May 2020

Natriuretic Peptide-Based Inclusion Criteria in a Heart Failure Clinical Trial: Insights From COMMANDER HF.

JACC Heart Fail 2020 05 11;8(5):359-368. Epub 2020 Mar 11.

Centre d'Investigations Cliniques-Plurithématique 1433, and INSERM U1116, CHRU, F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), Nancy, France. Electronic address:

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http://dx.doi.org/10.1016/j.jchf.2019.12.009DOI Listing
May 2020

Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction.

N Engl J Med 2020 05 28;382(20):1883-1893. Epub 2020 Mar 28.

From the Canadian VIGOUR Centre, University of Alberta, Edmonton, AB, Canada (P.W.A., J.E.); Charité University Medicine and German Heart Center, Berlin (B.P.), and Bayer, Wuppertal (L.R.) - all in Germany; Duke Clinical Research Institute, Duke University, Durham, NC (K.J.A., A.F.H., S.E.M., C.M.O.); University of Mississippi Medical Center, Jackson (J.B.); National Heart Center Singapore and Duke-National University of Singapore, Singapore (C.S.P.L.); the Cardiology Department, Wroclaw Medical University, Wroclaw, Poland (P.P.); University of Groningen, Groningen, the Netherlands (A.A.V.); Merck, Kenilworth, NJ (G.J., M.J.P., J.K.); and Inova Heart and Vascular Institute, Falls Church, VA (C.M.O.).

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http://dx.doi.org/10.1056/NEJMoa1915928DOI Listing
May 2020

Assessing the evidence-practice gap for heart failure in China: the Heart Failure Registry of Patient Outcomes (HERO) study design and baseline characteristics.

Eur J Heart Fail 2020 Apr 9;22(4):646-660. Epub 2019 Dec 9.

Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.

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http://dx.doi.org/10.1002/ejhf.1630DOI Listing
April 2020

Systolic Blood Pressure in Heart Failure With Preserved Ejection Fraction Treated With Sacubitril/Valsartan.

J Am Coll Cardiol 2020 Apr 16;75(14):1644-1656. Epub 2020 Mar 16.

Division of Cardiology, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2020.02.009DOI Listing
April 2020

Left atrial function in heart failure with preserved ejection fraction: a systematic review and meta-analysis.

Eur J Heart Fail 2020 Mar 9;22(3):472-485. Epub 2020 Jan 9.

Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

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http://dx.doi.org/10.1002/ejhf.1643DOI Listing
March 2020

Evaluation of high-sensitivity C-reactive protein and uric acid in vericiguat-treated patients with heart failure with reduced ejection fraction.

Eur J Heart Fail 2020 Mar 25. Epub 2020 Mar 25.

Department of Internal Medicine and Cardiology, Campus Virchow Klinikum, Charité Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/ejhf.1787DOI Listing
March 2020

Therapeutic approaches in heart failure with preserved ejection fraction: past, present, and future.

Clin Res Cardiol 2020 Mar 31. Epub 2020 Mar 31.

Klinik für Innere Medizin III-Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes, Kirrberger Straße, 66421, Homburg/Saar, Germany.

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http://dx.doi.org/10.1007/s00392-020-01633-wDOI Listing
March 2020

Reply in response to 'Defining a "frequent admitter" phenotype among patients with repeat heart failure admissions'.

Eur J Heart Fail 2020 Feb 21;22(2):385-386. Epub 2019 Oct 21.

National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore.

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http://dx.doi.org/10.1002/ejhf.1622DOI Listing
February 2020

Risk Factors for Heart Failure: 20-Year Population-Based Trends by Sex, Socioeconomic Status, and Ethnicity.

Circ Heart Fail 2020 Feb 14;13(2):e006472. Epub 2020 Feb 14.

Diabetes Research Centre (C.A.L., F.Z., H.O., M.D., K.K., U.T.K.), University of Leicester, United Kingdom.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.119.006472DOI Listing
February 2020

Women's Participation in Cardiovascular Clinical Trials From 2010 to 2017.

Circulation 2020 Feb 17;141(7):540-548. Epub 2020 Feb 17.

Global Heath Research Center, Duke Kunshan University, China (X.J., E.G., L.L.Y.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.043594DOI Listing
February 2020

Sex differences in heart failure.

Eur Heart J 2019 12;40(47):3859-3868c

University Medical Centre Groningen, Hanzeplein 1, GZ Groningen, The Netherlands.

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http://dx.doi.org/10.1093/eurheartj/ehz835DOI Listing
December 2019

Seipin Knockout Mice Develop Heart Failure With Preserved Ejection Fraction.

JACC Basic Transl Sci 2019 Dec 20;4(8):924-937. Epub 2019 Nov 20.

State Key Laboratory of Pharmaceutical Biotechnology and Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1016/j.jacbts.2019.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939002PMC
December 2019

Heart failure around the world.

Eur J Heart Fail 2019 Oct 16;21(10):1187-1196. Epub 2019 Aug 16.

National Heart Centre Singapore, Singapore.

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http://dx.doi.org/10.1002/ejhf.1585DOI Listing
October 2019

Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction.

N Engl J Med 2019 10 1;381(17):1609-1620. Epub 2019 Sep 1.

From the Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston (S.D.S., M.A.P., A.S.D., B.C.); the British Heart Foundation Cardiovascular Research Centre (J.J.V.M., P.S.J.) and the Robertson Centre for Biostatistics and Clinical Trials, Institute of Health and Well-being (J.C.), University of Glasgow, Glasgow, and the National Heart and Lung Institute, Royal Brompton and Harefield Hospitals, Imperial College, London (J.C.) - all in the United Kingdom; University of Minnesota, Minneapolis (I.S.A), and Mayo Clinic, Rochester (M.M.R.) - both in Minnesota; Shanghai Institute of Cardiovascular Diseases (J. Ge) and the Department of Cardiology (J.Z.), Zhongshan Hospital, Fudan University, Shanghai, China; National Heart Center Singapore and Duke-National University of Singapore, Singapore (C.S.P.L); National Association of Hospital Cardiologists Research Center, Florence (A.P.M.), and the Cardiology Division, Cardiovascular Department, Hospital Papa Giovanni XXIII, Bergamo (M.S.) - both in Italy; National University of Cordoba, Cordoba, Argentina (F.M.); Baylor University Medical Center, Dallas (M.P.); the Department of Internal Medicine and Cardiology, German Center for Cardiovascular Research partner site Berlin (B.P.), and the Department of Cardiology, Charité Universitätsmedizin, Campus Virchow-Klinikum (H.-D.D.) - both in Berlin; Institut de Cardiologie de Montréal, Université de Montréal, Montreal (J.L.R.); the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (D.J.V.); INSERM Centre d'Investigation Clinic 1433 and Université de Lorraine, Centre Hospitalier Régional et Universitaire, Nancy, France (F.Z.); Medical University of South Carolina and the Ralph H. Johnson Department of Veterans Affairs Medical Center, Charleston (M.R.Z.); National Research Center for Cardiology of the Ministry of Health of the Russian Federation, Moscow (S.A.B.); Community Heart Failure Program, Department of Cardiology, Bellvitge University Hospital and Bellvitge Institute for Biomedical Research, University of Barcelona, Barcelona (J.C.-C.); Department of Heart Failure-Transplantation, National Cardiovascular Institute, Bratislava, Slovakia (E.G.); Clinic of Cardiology, National Cardiology Hospital, Sofia, Bulgaria (T.K.); Disciplina de Cardiologia Faculdade de Medicina Pontifícia Universidade Católica de Campinas, São Paulo (J.F.K.S.); the Department of Noninvasive Cardiology, Medical University of Lodz, Lodz, Poland (M.L.); Heart and Vascular Center, Semmelweis University, Budapest, Hungary (B.M.); Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago (S.J.S); and Novartis Pharmaceuticals, East Hanover, NJ (A.R.R., J. Gong, V.C.S., M.P.L.).

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http://dx.doi.org/10.1056/NEJMoa1908655DOI Listing
October 2019

SGLT-2 Inhibitors in Heart Failure: Current Management, Unmet Needs, and Therapeutic Prospects.

J Am Heart Assoc 2019 10 12;8(20):e013389. Epub 2019 Oct 12.

Division of Cardiac Surgery Keenan Research Centre for Biomedical Science and Li Ka Shing Knowledge Institute of St Michael's Hospital University of Toronto Toronto Ontario Canada.

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http://dx.doi.org/10.1161/JAHA.119.013389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818035PMC
October 2019

World Heart Federation Roadmap for Heart Failure.

Glob Heart 2019 09;14(3):197-214

Hatter Institute for Cardiovascular Research in Africa, Department of Cardiology and Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.gheart.2019.07.004DOI Listing
September 2019

Choosing a Career in Heart Failure.

Authors:
Carolyn S P Lam

Circ Heart Fail 2019 07 12;12(7):e006026. Epub 2019 Jul 12.

National University Heart Centre, Singapore. Cardiovascular Academic Clinical Program, Duke-NUS Graduate Medical School, Singapore. Department of Cardiology, University Medical Centre Groningen, Netherlands. The George Institute for Global Health, Australia.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.119.006026DOI Listing
July 2019

Sex Differences in 1-Year Rehospitalization for Heart Failure and Myocardial Infarction After Primary Percutaneous Coronary Intervention.

Am J Cardiol 2019 06 19;123(12):1935-1940. Epub 2019 Mar 19.

National University Heart Centre, National University Hospital, Singapore; Cardiovascular Research Institute, National University of Singapore, Singapore; Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2019.03.021DOI Listing
June 2019

Understanding Contemporary Use of Thiazolidinediones.

Circ Heart Fail 2019 06;12(6):e005855

Saint Luke's Mid America Heart Institute (S.V.A., F.T., M.K.).

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.118.005855DOI Listing
June 2019

Empagliflozin and Heart Failure.

Circulation 2019 06 17;139(25):2831-2834. Epub 2019 Jun 17.

The George Institute for Global Health, Sydney, Australia (C.S.P.L., M.K.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.040921DOI Listing
June 2019

Prevalence and Prognostic Implications of Longitudinal Ejection Fraction Change in Heart Failure.

JACC Heart Fail 2019 04 6;7(4):306-317. Epub 2019 Mar 6.

Department of Medicine, Karolinska Institutet and Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jchf.2018.11.019DOI Listing
April 2019

Defining a 'frequent admitter' phenotype among patients with repeat heart failure admissions.

Eur J Heart Fail 2019 03 13;21(3):311-318. Epub 2018 Dec 13.

National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore.

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http://dx.doi.org/10.1002/ejhf.1348DOI Listing
March 2019

Sex Differences in Heart Failure With Preserved Ejection Fraction Pathophysiology: A Detailed Invasive Hemodynamic and Echocardiographic Analysis.

JACC Heart Fail 2019 03;7(3):239-249

Department of Cardiology, Alfred Hospital, Melbourne, Victoria, Australia; Heart Failure Research Group, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia; Department of Medicine, Monash University, Clayton, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jchf.2019.01.004DOI Listing
March 2019

Combining Circulating MicroRNA and NT-proBNP to Detect and Categorize Heart Failure Subtypes.

J Am Coll Cardiol 2019 03;73(11):1300-1313

Cardiovascular Research Institute, National University Health System, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Cardiac Department, National University Health System, Singapore; Christchurch Heart Institute, University of Otago, Christchurch, New Zealand. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2018.11.060DOI Listing
March 2019

Management of patients with diabetes and heart failure with reduced ejection fraction: An international comparison.

Diabetes Obes Metab 2019 02 25;21(2):261-266. Epub 2018 Sep 25.

Saint Luke's Mid America Heart Institute and University of Missouri-Kansas City, Kansas City, Missouri.

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http://doi.wiley.com/10.1111/dom.13511
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http://dx.doi.org/10.1111/dom.13511DOI Listing
February 2019

Discussion forum response to Canepa et al.

Eur Heart J 2019 02;40(8):705-706

Department of Cardiology, University Medical Center Groningen, University of Groningen, AB31, Hanzeplein 1, Groningen, the Netherlands.

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http://dx.doi.org/10.1093/eurheartj/ehy796DOI Listing
February 2019

Assessing use of patient-focused pharmacotherapy in glycemic management through the Diabetes Collaborative Registry (DCR).

J Diabetes Complications 2018 Nov 9;32(11):1035-1039. Epub 2018 Aug 9.

Saint Luke's Mid America Heart Institute, Kansas, MO, United States of America; University of Missouri-Kansas City, Kansas, MO, United States of America.

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http://dx.doi.org/10.1016/j.jdiacomp.2018.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021208PMC
November 2018

Rivaroxaban in Patients with Heart Failure, Sinus Rhythm, and Coronary Disease.

N Engl J Med 2018 10 27;379(14):1332-1342. Epub 2018 Aug 27.

From the Université de Lorraine, INSERM Unité 1116 and Clinical Investigation Center 1433, French Clinical Research Infrastructure Network, Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional et Universitaire de Nancy, Vandoeuvre lès Nancy, France (F.Z.); the Department of Cardiology and Berlin-Brandenburg Center for Regenerative Therapies, German Center for Cardiovascular Research partner site Berlin, Charité Universitätsmedizin Berlin, Berlin (S.D.A.); Janssen Research and Development, Raritan (W.M.B., C.C.N.), and Bayer U.S., Research and Development, Pharmaceuticals, Thrombosis and Hematology Therapeutic Area, Whippany (T.E.S.) - both in New Jersey; Robertson Centre for Biostatistics and Clinical Trials, University of Glasgow, Glasgow, and the National Heart and Lung Institute, Imperial College London, London - both in the United Kingdom (J.G.F.C.); Janssen Research and Development, Spring House, PA (M.F.); Northwestern University, Chicago (M.G.); National Heart Centre Singapore and Duke-National University of Singapore, Singapore (C.S.P.L.); the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (C.S.P.L., D.J.V.); Brigham and Women's Hospital and Harvard Medical School, Boston (M.R.M.); the Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis (J.D.N.); and the Department of Medicine, Cardiology Division, University of California, San Diego, San Diego (B.G.).

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http://www.nejm.org/doi/10.1056/NEJMoa1808848
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http://dx.doi.org/10.1056/NEJMoa1808848DOI Listing
October 2018

Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC).

Atherosclerosis 2018 10;277:234-255

Imperial Centre for Cardiovascular Disease Prevention (ICCP), Department of Primary Care and Public Health, School of Public Health, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.08.051DOI Listing
October 2018

Renal Function and Exercise Training in AmbulatoryHeart Failure Patients With a Reduced Ejection Fraction.

Am J Cardiol 2018 09 23;122(6):999-1007. Epub 2018 Jun 23.

Duke University Medical Center, Durham, North Carolina; Duke Clinical Research Institute, Durham, North Carolina.

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https://linkinghub.elsevier.com/retrieve/pii/S00029149183125
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http://dx.doi.org/10.1016/j.amjcard.2018.06.011DOI Listing
September 2018