Carolyn R Bertozzi

Carolyn R Bertozzi

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Carolyn R Bertozzi

Publications by authors named "Carolyn R Bertozzi"

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CRISPR-Cas9 screens identify regulators of antibody-drug conjugate toxicity.

Nat Chem Biol 2019 10 26;15(10):949-958. Epub 2019 Aug 26.

Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1038/s41589-019-0342-2DOI Listing
October 2019

Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs.

J Am Chem Soc 2019 Aug 16;141(34):13442-13453. Epub 2019 Aug 16.

Bio-Organic Chemistry Research Group, Department of Chemical Engineering and Chemistry , Eindhoven University of Technology , P.O. Box 513, 5600 MB Eindhoven , Netherlands.

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http://dx.doi.org/10.1021/jacs.9b04695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813768PMC
August 2019

Identification of new components of the RipC-FtsEX cell separation pathway of Corynebacterineae.

PLoS Genet 2019 Aug 22;15(8):e1008284. Epub 2019 Aug 22.

Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1008284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705760PMC
August 2019

Physical Principles of Membrane Shape Regulation by the Glycocalyx.

Cell 2019 Jun 2;177(7):1757-1770.e21. Epub 2019 May 2.

Robert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA; Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA; Field of Biophysics, Cornell University, Ithaca, NY 14853, USA; Kavli Institute at Cornell for Nanoscale Science, Ithaca, NY 14853, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768631PMC
June 2019

A Sugar Cloak of Invisibility.

Biochemistry 2019 May 1;58(19):2385-2386. Epub 2019 May 1.

Department of Chemistry , Stanford University , Stanford , California 94305 , United States.

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http://dx.doi.org/10.1021/acs.biochem.9b00170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608708PMC
May 2019

Sequential assembly of the septal cell envelope prior to V snapping in Corynebacterium glutamicum.

Nat Chem Biol 2019 03 21;15(3):221-231. Epub 2019 Jan 21.

Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1038/s41589-018-0206-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693342PMC
March 2019

Imaging Mycobacterial Trehalose Glycolipids.

Methods Enzymol 2018 21;598:355-369. Epub 2017 Nov 21.

Stanford University, Stanford, CA, United States; Howard Hughes Medical Institute, Stanford University, Chevy Chase, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2017.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038140PMC
January 2019

The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation.

iScience 2019 Jan 20;11:160-177. Epub 2018 Dec 20.

Department of Tumor Immunology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Geert Grooteplein 28, 6525GA Nijmegen, the Netherlands; Department of Molecular Immunology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, Groningen 9747 AG, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2018.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319320PMC
January 2019

Site-specific incorporation of quadricyclane into a protein and photocleavage of the quadricyclane ligation adduct.

Bioorg Med Chem 2018 10 4;26(19):5280-5290. Epub 2018 Apr 4.

Department of Chemistry, Stanford University, Stanford, CA 94305, United States; Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, United States; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2018.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170726PMC
October 2018

Cyclopropane Modification of Trehalose Dimycolate Drives Granuloma Angiogenesis and Mycobacterial Growth through Vegf Signaling.

Cell Host Microbe 2018 10;24(4):514-525.e6

Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Immunology, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19313128183048
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http://dx.doi.org/10.1016/j.chom.2018.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201760PMC
October 2018

Is the Nobel Prize in Chemistry Having a Boston Red Sox Moment?

ACS Cent Sci 2018 Oct;4(10):1291

Department of Chemistry, Stanford University.

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http://dx.doi.org/10.1021/acscentsci.8b00740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202648PMC
October 2018

Computation-Guided Rational Design of a Peptide Motif That Reacts with Cyanobenzothiazoles via Internal Cysteine-Lysine Relay.

J Org Chem 2018 07 30;83(14):7467-7479. Epub 2018 May 30.

Department of Chemistry , University of California , Berkeley , California 94720 , United States.

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http://dx.doi.org/10.1021/acs.joc.8b00625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258261PMC
July 2018

Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics.

J Am Chem Soc 2018 06 30;140(23):7046-7051. Epub 2018 May 30.

Center for Tissue Regeneration, Repair and Restoration , V.A. Palo Alto Healthcare System , Palo Alto , California 94304 , United States.

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http://dx.doi.org/10.1021/jacs.8b03074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598694PMC
June 2018

Isotype-specific agglutination-PCR (ISAP): A sensitive and multiplex method for measuring allergen-specific IgE.

J Allergy Clin Immunol 2018 05 14;141(5):1901-1904.e15. Epub 2017 Dec 14.

Department of Pathology, Microbiology and Immunology, Stanford University School of Medicine, Stanford, Calif; Sean N. Parker Center for Allergy and Asthma Research, Stanford, Calif; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, Calif. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.11.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938140PMC
May 2018

Acute Modulation of Mycobacterial Cell Envelope Biogenesis by Front-Line Tuberculosis Drugs.

Angew Chem Int Ed Engl 2018 05 14;57(19):5267-5272. Epub 2018 Apr 14.

Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1002/anie.201712020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924460PMC
May 2018

Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement.

Cell 2018 01;172(1-2):305-317.e10

Program in Cell Biology, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON M5C 1N8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.12.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929997PMC
January 2018

Werner Reutter: A Visionary Pioneer in Molecular Glycobiology.

Chembiochem 2017 07 16;18(13):1141-1145. Epub 2017 Jun 16.

Leibniz-Forschungsinstitut für Molekulare Pharmakologie FMP, Department of Chemical Biology, Robert-Roessle-Strasse 10, 13125, Berlin, Germany.

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http://dx.doi.org/10.1002/cbic.201700277DOI Listing
July 2017

Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics.

Angew Chem Int Ed Engl 2017 07 26;56(31):8992-8997. Epub 2017 Jun 26.

Department of Chemistry, Stanford University, Stanford, CA, 94305-4401, USA.

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http://dx.doi.org/10.1002/anie.201701424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675001PMC
July 2017

Development of IsoTaG, a Chemical Glycoproteomics Technique for Profiling Intact N- and O-Glycopeptides from Whole Cell Proteomes.

J Proteome Res 2017 04 28;16(4):1706-1718. Epub 2017 Feb 28.

Department of Chemistry; §School of Engineering; #Canary Center at Stanford for Cancer Early Detection, Stanford University School of Medicine; ∇Howard Hughes Medical Institute, Stanford University , Stanford, California 94305, United States.

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http://dx.doi.org/10.1021/acs.jproteome.6b01053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507588PMC
April 2017

Subcellular Partitioning and Intramacrophage Selectivity of Antimicrobial Compounds against Mycobacterium tuberculosis.

Antimicrob Agents Chemother 2017 03 23;61(3). Epub 2017 Feb 23.

Graduate Group in Infectious Diseases and Immunity, School of Public Health, University of California, Berkeley, California, USA

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http://aac.asm.org/lookup/doi/10.1128/AAC.01639-16
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http://dx.doi.org/10.1128/AAC.01639-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328571PMC
March 2017

Visualization of mycobacterial membrane dynamics in live cells.

J Am Chem Soc 2017 03 23;139(9):3488-3495. Epub 2017 Feb 23.

Department of Chemistry, Stanford University , Stanford, California 94305, United States.

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http://dx.doi.org/10.1021/jacs.6b12541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345120PMC
March 2017

Click-Chemistry Based High Throughput Screening Platform for Modulators of Ras Palmitoylation.

Sci Rep 2017 01 23;7:41147. Epub 2017 Jan 23.

Department of Integrated Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/srep41147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5255568PMC
January 2017

Chemical Glycoproteomics.

Chem Rev 2016 Dec 18;116(23):14277-14306. Epub 2016 Nov 18.

Verily Life Sciences , 269 East Grand Ave., South San Francisco, California 94080, United States.

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http://dx.doi.org/10.1021/acs.chemrev.6b00023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327817PMC
December 2016

A Season of Giving to Science.

ACS Cent Sci 2016 Dec;2(12):872-873

American Chemical Society.

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http://dx.doi.org/10.1021/acscentsci.6b00382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200921PMC
December 2016

Ingredients for a Positive Safety Culture.

ACS Cent Sci 2016 Nov;2(11):764-766

Department of Chemistry, Stanford University.

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http://dx.doi.org/10.1021/acscentsci.6b00341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126708PMC
November 2016

Biosynthesis and Regulation of Sulfomenaquinone, a Metabolite Associated with Virulence in Mycobacterium tuberculosis.

ACS Infect Dis 2016 11 15;2(11):800-806. Epub 2016 Aug 15.

Department of Nutritional Science and Toxicology, University of California, Berkeley , 127 Morgan Hall, Berkeley, California 94720, United States.

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http://pubs.acs.org/doi/10.1021/acsinfecdis.6b00106
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http://dx.doi.org/10.1021/acsinfecdis.6b00106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505729PMC
November 2016

Piperidine-based glycodendrons as protein N-glycan prosthetics.

Bioorg Med Chem 2016 10 25;24(20):4791-4800. Epub 2016 May 25.

Department of Chemistry, Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052108PMC
http://dx.doi.org/10.1016/j.bmc.2016.05.050DOI Listing
October 2016

Proteomic dataset for altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells.

Data Brief 2016 Sep 30;8:342-9. Epub 2016 May 30.

Department of Molecular Medicine, Laval University, Québec PQ, Canada; Centre de recherche du CHU de Québec, L'Hôtel-Dieu de Québec, Québec PQ, Canada.

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http://dx.doi.org/10.1016/j.dib.2016.05.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908283PMC
September 2016

Precision glycocalyx editing as a strategy for cancer immunotherapy.

Proc Natl Acad Sci U S A 2016 09 22;113(37):10304-9. Epub 2016 Aug 22.

Department of Chemistry, Stanford University, Stanford, CA 94305-4404; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305-4404

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http://dx.doi.org/10.1073/pnas.1608069113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027407PMC
September 2016

A fluorogenic screening platform enables directed evolution of an alkyne biosynthetic tool.

Chem Commun (Camb) 2016 Sep 25;52(75):11239-42. Epub 2016 Aug 25.

Department of Chemical and Biomolecular Engineering, University of California, Berkeley, CA 94704, USA.

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http://dx.doi.org/10.1039/c6cc05990bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023497PMC
September 2016

A metabolic labeling approach for glycoproteomic analysis reveals altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells.

J Proteomics 2016 08 17;145:91-102. Epub 2016 Apr 17.

Department of Molecular Medicine, Laval University, Québec, PQ, Canada; Centre de recherche du CHU de Québec, L'Hôtel-Dieu de Québec, Québec, PQ, Canada.

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http://dx.doi.org/10.1016/j.jprot.2016.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436706PMC
August 2016

Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction.

J Am Chem Soc 2016 08 17;138(34):10722-5. Epub 2016 Aug 17.

Departments of †Chemistry, ‡Molecular and Cell Biology, and §Molecular Environmental Biology, University of California , Berkeley, California 94720, United States.

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http://dx.doi.org/10.1021/jacs.6b03861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327792PMC
August 2016

Nuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesis.

Proc Natl Acad Sci U S A 2016 08 5;113(33):E4820-7. Epub 2016 Aug 5.

Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720;

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http://dx.doi.org/10.1073/pnas.1609135113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995945PMC
August 2016

Back to the Lecture.

ACS Cent Sci 2016 Aug;2(8):483-5

Department of Chemistry, Stanford University.

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http://dx.doi.org/10.1021/acscentsci.6b00224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999963PMC
August 2016

Exercise Your Brain.

ACS Cent Sci 2016 Jul;2(7):430-1

Department of Chemistry, Stanford University.

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http://dx.doi.org/10.1021/acscentsci.6b00194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965850PMC
July 2016

Click-EM for imaging metabolically tagged nonprotein biomolecules.

Nat Chem Biol 2016 06 25;12(6):459-65. Epub 2016 Apr 25.

Department of Pharmacology, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1038/nchembio.2076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871776PMC
June 2016

Sialic Acid Glycobiology Unveils Trypanosoma cruzi Trypomastigote Membrane Physiology.

PLoS Pathog 2016 Apr 8;12(4):e1005559. Epub 2016 Apr 8.

Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín, San Martín, Buenos Aires, Argentina and Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.

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http://dx.doi.org/10.1371/journal.ppat.1005559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825991PMC
April 2016

Achieving Gender Balance in the Chemistry Professoriate Is Not Rocket Science.

ACS Cent Sci 2016 Apr;2(4):181-2

Department of Chemistry, Stanford University.

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http://dx.doi.org/10.1021/acscentsci.6b00102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850509PMC
April 2016

Isotope Targeted Glycoproteomics (IsoTaG) to Characterize Intact, Metabolically Labeled Glycopeptides from Complex Proteomes.

Curr Protoc Chem Biol 2016 Mar 16;8(1):59-82. Epub 2016 Mar 16.

Department of Chemistry, Stanford University, Stanford, California.

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http://dx.doi.org/10.1002/9780470559277.ch150185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809415PMC
March 2016

Ultrasensitive Antibody Detection by Agglutination-PCR (ADAP).

ACS Cent Sci 2016 Mar 16;2(3):139-147. Epub 2016 Feb 16.

Department of Chemistry and Howard Hughes Medical Institute, Stanford University, Stanford, California 94305, United States; Department of Chemistry and Howard Hughes Medical Institute, Stanford University, Stanford, California 94305, United States.

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http://dx.doi.org/10.1021/acscentsci.5b00340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819452PMC
March 2016

Happy Birthday ACS Central Science!

ACS Cent Sci 2016 Mar;2(3):117-8

Department of Chemistry, Stanford University.

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http://dx.doi.org/10.1021/acscentsci.6b00070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827488PMC
March 2016

Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis.

Cell 2016 Jan;164(1-2):128-140

Program in Cell Biology, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Keenan Research Centre, St. Michael's Hospital, Toronto, ON M5S 1T8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.11.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715264PMC
January 2016

A Bioorthogonal Reaction of N-Oxide and Boron Reagents.

Angew Chem Int Ed Engl 2015 Dec 16;54(52):15777-81. Epub 2015 Nov 16.

Department of Chemistry and Howard Hughes Medical Institute, Stanford University, 380 Roth Way, Stanford, CA 94305 (USA).

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http://dx.doi.org/10.1002/anie.201508861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715665PMC
December 2015

Glycocalyx Engineering with a Recycling Glycopolymer that Increases Cell Survival In Vivo.

Angew Chem Int Ed Engl 2015 Dec 13;54(52):15782-8. Epub 2015 Nov 13.

Department of Chemistry, Stanford University, Stanford, CA 94305-4401 (USA).

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http://dx.doi.org/10.1002/anie.201508783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736730PMC
December 2015

Advice for "Hunting Season".

ACS Cent Sci 2015 Dec;1(9):464-5

Department of Chemistry, Stanford University.

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http://dx.doi.org/10.1021/acscentsci.5b00386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827657PMC
December 2015

Chemically tunable mucin chimeras assembled on living cells.

Proc Natl Acad Sci U S A 2015 Oct 29;112(41):12574-9. Epub 2015 Sep 29.

Department of Chemistry, Stanford University, Stanford, CA 94305; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305

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http://dx.doi.org/10.1073/pnas.1516127112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611660PMC
October 2015

Systemic Fluorescence Imaging of Zebrafish Glycans with Bioorthogonal Chemistry.

Angew Chem Int Ed Engl 2015 Sep 31;54(39):11504-10. Epub 2015 Jul 31.

Department of Chemistry and Howard Hughes Medical Institute, Stanford University, 333 Campus Drive, Stanford, CA 94305.

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http://dx.doi.org/10.1002/anie.201504249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694582PMC
September 2015

It's about the Students.

ACS Cent Sci 2015 Sep;1(6):279-80

Department of Chemistry, Stanford University.

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http://dx.doi.org/10.1021/acscentsci.5b00301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827521PMC
September 2015

Chemical Lectinology: Tools for Probing the Ligands and Dynamics of Mammalian Lectins In Vivo.

Chem Biol 2015 Aug 6;22(8):983-93. Epub 2015 Aug 6.

Department of Chemistry and Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305-4401, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2015.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567249PMC
August 2015

Live-Cell Labeling of Specific Protein Glycoforms by Proximity-Enhanced Bioorthogonal Ligation.

J Am Chem Soc 2015 Aug 17;137(33):10452-5. Epub 2015 Aug 17.

Departments of Chemistry and Molecular and Cell Biology and the Howard Hughes Medical Institute, University of California , Berkeley, California 94720, United States.

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http://dx.doi.org/10.1021/jacs.5b04279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748840PMC
August 2015

On Being a Closer.

ACS Cent Sci 2015 Aug;1(5):217-8

Department of Chemistry, Stanford University.

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http://dx.doi.org/10.1021/acscentsci.5b00275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827550PMC
August 2015

On the Move.

ACS Cent Sci 2015 Jul;1(4):157-8

Department of Chemistry, Stanford University.

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http://dx.doi.org/10.1021/acscentsci.5b00245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827477PMC
July 2015

Isotope-targeted glycoproteomics (IsoTaG): a mass-independent platform for intact N- and O-glycopeptide discovery and analysis.

Nat Methods 2015 Jun 20;12(6):561-7. Epub 2015 Apr 20.

1] Department of Chemistry, University of California, Berkeley, California, USA. [2] Department of Molecular and Cell Biology, University of California, Berkeley, California, USA. [3] Howard Hughes Medical Institute, Berkeley, California, USA.

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http://dx.doi.org/10.1038/nmeth.3366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599779PMC
June 2015

CalFluors: A Universal Motif for Fluorogenic Azide Probes across the Visible Spectrum.

J Am Chem Soc 2015 Jun 2;137(22):7145-51. Epub 2015 Jun 2.

∥Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, United States.

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http://dx.doi.org/10.1021/jacs.5b02383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487548PMC
June 2015

A Meeting Full of Firsts.

ACS Cent Sci 2015 May;1(2):57

Department of Chemistry, HHMI/Stanford University.

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http://dx.doi.org/10.1021/acscentsci.5b00185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827500PMC
May 2015

Xylosyltransferase II is the predominant isoenzyme which is responsible for the steady-state level of xylosyltransferase activity in human serum.

Biochem Biophys Res Commun 2015 Apr 3;459(3):469-74. Epub 2015 Mar 3.

Institut für Laboratoriums- und Transfusionsmedizin, Herz- und Diabeteszentrum Nordrhein-Westfalen, Universitätsklinik der Ruhr-Universität Bochum, Georgstraße 11, 32545 Bad Oeynhausen, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2015.02.129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598695PMC
April 2015

Host actin polymerization tunes the cell division cycle of an intracellular pathogen.

Cell Rep 2015 Apr 16;11(4):499-507. Epub 2015 Apr 16.

Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.03.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417095PMC
April 2015

Illumination of growth, division and secretion by metabolic labeling of the bacterial cell surface.

FEMS Microbiol Rev 2015 Mar 23;39(2):184-202. Epub 2015 Jan 23.

Department of Chemistry, University of California, Berkeley, CA 94720, USA Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA

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http://dx.doi.org/10.1093/femsre/fuu012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462956PMC
March 2015

The Centrality of Chemistry.

ACS Cent Sci 2015 Mar 23;1(1):1-2. Epub 2015 Mar 23.

Department of Chemistry, HHMI/UC Berkeley.

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http://dx.doi.org/10.1021/acscentsci.5b00090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827486PMC
March 2015

Site-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug development.

Bioconjug Chem 2015 Feb 30;26(2):176-92. Epub 2015 Jan 30.

Departments of Chemistry and ‡Molecular and Cell Biology and §Howard Hughes Medical Institute, University of California , Berkeley, California 94720, United States.

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http://dx.doi.org/10.1021/bc5004982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335810PMC
February 2015

The rv1184c locus encodes Chp2, an acyltransferase in Mycobacterium tuberculosis polyacyltrehalose lipid biosynthesis.

J Bacteriol 2015 Jan 20;197(1):201-10. Epub 2014 Oct 20.

Department of Pharmacological Sciences, Stony Brook University, Stony Brook, New York, USA

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http://dx.doi.org/10.1128/JB.02015-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288680PMC
January 2015

Formylglycine, a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.

ACS Chem Biol 2015 Jan;10(1):72-84

Department of Molecular and Cell Biology, University of California, Berkeley , Berkeley, California 94720, United States.

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http://dx.doi.org/10.1021/cb500897wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492166PMC
January 2015

Design strategies for bioorthogonal smart probes.

Org Biomol Chem 2014 Dec 15;12(46):9307-20. Epub 2014 Oct 15.

Department of Chemistry, University of California, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1039/c4ob01632gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259128PMC
December 2014

Subpolar addition of new cell wall is directed by DivIVA in mycobacteria.

Proc Natl Acad Sci U S A 2014 Aug 21;111(31):E3243-51. Epub 2014 Jul 21.

Department of Microbiology and Physiological Systems andHoward Hughes Medical Institute, University of Massachusetts Medical School, Worcester, MA 01605;

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http://dx.doi.org/10.1073/pnas.1402158111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128124PMC
August 2014

The cancer glycocalyx mechanically primes integrin-mediated growth and survival.

Nature 2014 Jul 25;511(7509):319-25. Epub 2014 Jun 25.

1] Department of Surgery and Center for Bioengineering and Tissue Regeneration, University of California, San Francisco, California 94143, USA [2] Bay Area Physical Sciences-Oncology Program, University of California, Berkeley, California 94720, USA [3] Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94143, USA [4] Departments of Anatomy and Bioengineering and Therapeutic Sciences and Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/nature13535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487551PMC
July 2014

An expanded set of fluorogenic sulfatase activity probes.

Chembiochem 2014 May 24;15(8):1101-5. Epub 2014 Apr 24.

Departments of Chemistry and Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, B84 Hildebrand Hall, #1460, Berkeley, CA 94720 (USA).

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http://dx.doi.org/10.1002/cbic.201400032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084507PMC
May 2014

Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

Bioconjug Chem 2014 Apr 7;25(4):788-95. Epub 2014 Apr 7.

Departments of Chemistry and ‡Molecular and Cell Biology and §Howard Hughes Medical Institute, ∥QB3/Chemistry Mass Spectrometry Facility, University of California , Berkeley, California 94720, United States.

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http://dx.doi.org/10.1021/bc500061sDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004622PMC
April 2014

Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes.

Proc Natl Acad Sci U S A 2014 Apr 31;111(15):5456-61. Epub 2014 Mar 31.

Departments of Chemistry and Molecular and Cell Biology and Howard Hughes Medical Institute, University of California, Berkeley, CA 94720.

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http://dx.doi.org/10.1073/pnas.1322727111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992625PMC
April 2014

A visualizable chain-terminating inhibitor of glycosaminoglycan biosynthesis in developing zebrafish.

Angew Chem Int Ed Engl 2014 Mar 19;53(13):3347-52. Epub 2014 Feb 19.

Department of Chemistry and Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, CA 94720 (USA).

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http://dx.doi.org/10.1002/anie.201310569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029504PMC
March 2014

A homologation approach to the synthesis of difluorinated cycloalkynes.

Org Lett 2014 Mar 3;16(6):1634-7. Epub 2014 Mar 3.

Department of Chemistry, University of California , Berkeley, California 94720, United States.

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http://dx.doi.org/10.1021/ol500260dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993865PMC
March 2014

Glycotherapy: new advances inspire a reemergence of glycans in medicine.

Chem Biol 2014 Jan 21;21(1):16-37. Epub 2013 Nov 21.

Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2013.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111574PMC
January 2014

Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion.

Nat Chem Biol 2014 Jan 24;10(1):69-75. Epub 2013 Nov 24.

1] Department of Chemistry, University of California-Berkeley, Berkeley, California, USA. [2] Molecular and Cell Biology, University of California-Berkeley, Berkeley, California, USA. [3] Howard Hughes Medical Institute, University of California-Berkeley, Berkeley, California, USA.

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http://dx.doi.org/10.1038/nchembio.1388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893890PMC
January 2014

Mycobacterial lipid logic.

Cell Host Microbe 2014 Jan;15(1):1-2

Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2013.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123792PMC
January 2014

Imaging the glycosylation state of cell surface glycoproteins by two-photon fluorescence lifetime imaging microscopy.

Angew Chem Int Ed Engl 2013 Dec 20;52(52):14045-9. Epub 2013 Nov 20.

Departments of Chemistry and Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, CA 94720 (USA).

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http://doi.wiley.com/10.1002/anie.201307512
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http://dx.doi.org/10.1002/anie.201307512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920747PMC
December 2013

Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase.

Proc Natl Acad Sci U S A 2013 Dec 5;110(52):E5069-77. Epub 2013 Dec 5.

Departments of Chemistry and Molecular and Cell Biology, California Institute for Quantitative Biosciences (QB3), and Howard Hughes Medical Institute, University of California, Berkeley, CA 94720.

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http://dx.doi.org/10.1073/pnas.1321205110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876250PMC
December 2013

In vivo chemistry.

Curr Opin Chem Biol 2013 Oct 21;17(5):717-8. Epub 2013 Oct 21.

Departments of Chemistry, Berkeley, CA 94720, United States; Molecular and Cell Biology, Berkeley, CA 94720, United States; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cbpa.2013.10.012DOI Listing
October 2013