Publications by authors named "Carolyn Owen"

54Publications

Cucurbit chlorotic yellows virus p22 suppressor of RNA silencing binds single-, double-stranded long and short interfering RNA molecules in vitro.

Virus Res 2020 04 8;279:197887. Epub 2020 Feb 8.

Department of Sustainable Agriculture, Mediterranean Agronomic Institute of Chania, Alsylio Agrokepion, GR-73100, Chania, Crete, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.virusres.2020.197887DOI Listing
April 2020

Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL.

N Engl J Med 2018 12 1;379(26):2517-2528. Epub 2018 Dec 1.

From Ohio State University Comprehensive Cancer Center, Columbus (J.A.W., A.S.R., N.A.H., W.Z., K.A.R., G.L., J.S.B., H.G.O., J.C.B.); the Alliance Statistics and Data Center (A.S.R., A.M.B., B.M.-E., B.F., S.J.M.), Mayo Clinic (W.D., S.A.P., M.L.), Rochester, MN; Washington University School of Medicine, St. Louis (N.L.B.); Duke Cancer Institute, Duke University Medical Center, Durham (D.M.B., H.E.), and First Health of the Carolinas Cancer Center, Pinehurst (C.K.) - both in North Carolina; the University of Rochester Medical Center, Rochester, NY (P.M.B.); Stanford University School of Medicine, Stanford (S.C.), and the City of Hope Comprehensive Cancer Center, Duarte (A.H.) - both in California; Dana-Farber Partners CancerCare (J.R.B., R.M.S.) and the Massachusetts General Hospital Cancer Center (J.S.A.) - both in Boston; Fort Wayne Medical Oncology and Hematology, Fort Wayne, IN (S.N.); University of Chicago Comprehensive Cancer Center (R.A.L.) and Loyola University Chicago (S.E.S.) - both in Chicago; the University of Calgary, Tom Baker Cancer Centre, Calgary, AB, Canada (C.O.); and the Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD (R.F.L.).

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http://dx.doi.org/10.1056/NEJMoa1812836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325637PMC
December 2018

A Thioredoxin Domain-Containing Protein Interacts with Triple Gene Block Protein 1.

Int J Mol Sci 2018 Nov 25;19(12). Epub 2018 Nov 25.

Mediterranean Agronomic Institute of Chania, Department of Sustainable Agriculture, Alsylio Agrokepio, GR-73100 Chania, Greece.

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http://www.mdpi.com/1422-0067/19/12/3747
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http://dx.doi.org/10.3390/ijms19123747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320799PMC
November 2018

Venetoclax-Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia.

N Engl J Med 2018 Mar;378(12):1107-1120

From the Peter MacCallum Cancer Centre, Royal Melbourne Hospital, and University of Melbourne, Melbourne, VIC (J.F.S.), and the John Curtin School of Medical Research, Australian National University, Canberra, ACT (J.D.) - all in Australia; the University of California School of Medicine, San Diego (T.J.K.), and Genentech, South San Francisco (E.A.P., Y.L., M. Mobasher) - both in California; University Hospital Cologne and the Center for Integrated Oncology Cologne-Bonn, Cologne, Germany (B.E.); St. James's University Hospital, Leeds (P.H.), and F. Hoffmann-La Roche, Welwyn Garden City (M.B., K.H.) - both in the United Kingdom; Segal Cancer Center, Lady Davis Institute, Jewish General Hospital, Montreal (S.A.), and the Departments of Medicine and Oncology, University of Calgary, Calgary, AB (C.O.) - all in Canada; Memorial Sloan Kettering Cancer Center, New York (J.G.); the Department of Hematology, Medical University of Lodz and Copernicus Memorial Hospital, Lodz, Poland (T.R.); Hospital Universitario 12 de Octubre, Madrid (J.D.S.); Medical University of Vienna, Department of Medicine I, Division of Hematology and Hemostaseology, Vienna (U.J.); the Department of Hematology, Centre Hospitalier Universitaire Montpellier, Montpellier, France (G.C.); the Department of Onco-Hematology, Division of Hematology, Niguarda Cancer Center, Niguarda Hospital, Milan (M. Montillo); AbbVie, North Chicago, IL (R.H.); and the Department of Hematology, Cancer Center Amsterdam, Academic Medical Center, Amsterdam (A.P.K.).

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http://dx.doi.org/10.1056/NEJMoa1713976DOI Listing
March 2018

Blastic plasmacytoid dendritic cell neoplasm: challenges and future prospects.

Blood Lymphat Cancer 2017 11;7:85-93. Epub 2017 Dec 11.

Division of Hematology and Hematological Malignancies, University of Calgary, Foothills Medical Centre, Calgary, AB, Canada,

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http://dx.doi.org/10.2147/BLCTT.S132060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467341PMC
December 2017

Obinutuzumab for the First-Line Treatment of Follicular Lymphoma.

N Engl J Med 2017 10;377(14):1331-1344

From King's College Hospital (R.M.) and the Cancer Research UK and University College London Cancer Trials Centre (E.P., W.T.), London, and the Cancer Research UK Centre, University of Southampton, Southampton (A.D.) - all in the United Kingdom; the Tokai University School of Medicine, Isehara, Japan (K.A.); the University of Kiel, Kiel (W.K.), Gemeinschaftspraxis, Würzburg (R. Schlag), HELIOS Klinikum Erfurt, Erfurt (M.H.), and the Ludwig-Maximilians-University Hospital Grosshadern, Munich (W.H.) - all in Germany; Monash Health and Monash University (S.O.) and the Peter MacCallum Cancer Centre and University of Melbourne (J.F.S.), Melbourne, VIC, Australia; Foothills Medical Centre and Tom Baker Cancer Centre, Calgary, AB (C.O.), and the Cross Cancer Institute, Edmonton, AB (R. Sangha) - both in Canada; Charles University, Prague, Czech Republic (M.T.); and F. Hoffmann-La Roche, Basel, Switzerland (M.W., G.F.-R., K.R., T.M.).

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http://dx.doi.org/10.1056/NEJMoa1614598DOI Listing
October 2017

Use of minimal residual disease assessment in the treatment of chronic lymphocytic leukemia.

Leuk Lymphoma 2017 12 16;58(12):2777-2785. Epub 2017 May 16.

f Hoffmann-La Roche , Basel , Switzerland.

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http://dx.doi.org/10.1080/10428194.2017.1318439DOI Listing
December 2017

Azacitidine in the treatment of blastic plasmacytoid dendritic cell neoplasm: a report of 3 cases.

Leuk Lymphoma 2016 11 17;57(11):2720-2. Epub 2016 Mar 17.

a Cumming School of Medicine , Tom Baker Cancer Centre, University of Calgary , Calgary , Alberta , Canada ;

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http://dx.doi.org/10.3109/10428194.2016.1160084DOI Listing
November 2016

Quantifying Benefit of Autologous Transplantation for Relapsed Follicular Lymphoma Patients via Instrumental Variable Analysis.

Biol Blood Marrow Transplant 2016 May 16;22(5):941-8. Epub 2016 Jan 16.

Departments of Oncology and Medicine, University of Calgary and Tom Baker Cancer Centre, Calgary, Alberta, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2016.01.015DOI Listing
May 2016

Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia.

N Engl J Med 2015 Dec 6;373(25):2425-37. Epub 2015 Dec 6.

From the University of Texas MD Anderson Cancer Center, Houston (J.A.B.); Azienda Ospedaliera Niguarda Cà Granda (A.T.) and Università Vita-Salute San Raffaele and IRCCS Istituto Scientifico San Raffaele (P.G.), Milan, and the Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara (G.G.) - all in Italy; Wilmot Cancer Institute, University of Rochester, Rochester, NY (P.M.B.); Medical University of Lodz and Copernicus Memorial Hospital, Lodz (T.R.), the Department of Cancer Prevention, School of Public Health, Medical University of Silesia, Katowice (S.G.), and the Department of Hematology, University Clinical Center of Medical University of Gdansk, Gdansk (A.H.) - all in Poland; Tom Baker Cancer Centre, Calgary, AB, Canada (C.O.); Rabin Medical Center, Beilinson Hospital and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (O.B.), and Hadassah University Hospital, Hebrew University Medical School, Jerusalem (A.P.) - both in Israel; Leeds Teaching Hospitals, St. James Institute of Oncology, Leeds (P.H.), Kings College Hospital, London (S.D.), Royal Bournemouth Hospital, Bournemouth (H.M.), and University of Oxford, Oxford (A.S.) - all in the United Kingdom; Washington University School of Medicine, St. Louis (N.L.B.); Jiangsu Province Hospital, Nanjing, China (J.L.); North Shore Hospital, Auckland, New Zealand (D. Simpson); Stanford University School of Medicine, Stanford (S.C.), City of Hope National Medical Center, Duarte (T.S.), Pharmacyclics, Sunnyvale (D. Suri, M.C., F.C., L.S., D.F.J.), and Moores Cancer Center, University of California, San Diego, San Diego (T.J.K.) - all in California; St. Vincent's Hospital, University of Melbourne (H.Q.), and Peter MacCallum Cancer Centre and St. Vincent's Hospital (C.S.T.), Melbourne, VIC, Australia; Institute of Blood Pathology and Transfusion Medicine, National Academy of Medical Sciences of Ukraine, Lviv, Ukraine (Z.M.); Norton Cancer Institute, Louisville, KY (D.A.S.);

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http://dx.doi.org/10.1056/NEJMoa1509388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722809PMC
December 2015

Novel Therapies for Chronic Lymphocytic Leukemia: A Canadian Perspective.

Clin Lymphoma Myeloma Leuk 2015 Nov 5;15(11):627-634.e5. Epub 2015 Aug 5.

BC Cancer Agency, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.clml.2015.07.649DOI Listing
November 2015

Obinutuzumab for the treatment of patients with previously untreated chronic lymphocytic leukemia: overview and perspective.

Ther Adv Hematol 2015 Aug;6(4):161-70

Departments of Medicine and Oncology, University of Calgary, Alberta, Canada.

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http://dx.doi.org/10.1177/2040620715586528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530370PMC
August 2015

A canadian perspective on the first-line treatment of chronic lymphocytic leukemia.

Clin Lymphoma Myeloma Leuk 2015 Jun 26;15(6):303-13. Epub 2015 Mar 26.

Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S21522650150010
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http://dx.doi.org/10.1016/j.clml.2015.03.002DOI Listing
June 2015

Clinical role of obinutuzumab in the treatment of naive patients with chronic lymphocytic leukemia.

Biologics 2015 16;9:13-22. Epub 2015 Feb 16.

Department of Hematology, Tom Baker Cancer Centre, Calgary, AB, Canada.

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http://dx.doi.org/10.2147/BTT.S61600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337412PMC
March 2015

Comparative effectiveness analysis of different salvage therapy intensities used for diffuse large B-cell lymphoma in Northern or Southern Alberta: an instrumental variable analysis.

Leuk Lymphoma 2015 Jun 3;56(6):1756-62. Epub 2014 Nov 3.

Department of Oncology and Medicine, University of Calgary, Tom Baker Cancer Centre , Calgary, AB , Canada.

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http://dx.doi.org/10.3109/10428194.2014.971409DOI Listing
June 2015

Obinutuzumab for B-cell malignancies.

Expert Opin Biol Ther 2014 Aug 23;14(8):1197-205. Epub 2014 May 23.

University of Calgary, Tom Baker Cancer Centre, Division of Hematology and Hematological Malignancies , 603 South Tower, Foothills Medical Centre, 1403-29th St NW, Calgary, Alberta, T2N 2T9 , Canada

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http://dx.doi.org/10.1517/14712598.2014.922535DOI Listing
August 2014

Obinutuzumab plus chlorambucil in patients with CLL and coexisting conditions.

N Engl J Med 2014 Mar 8;370(12):1101-10. Epub 2014 Jan 8.

From the German CLL Study Group, Department I of Internal Medicine, Center of Integrated Oncology Cologne-Bonn, University Hospital Cologne, Cologne (V.G., K.F., A.E., B.E., C.M.W., K.-A.K., M.H.), the Department for Geriatric Medicine and Research, St. Marien Hospital and University of Cologne, Cologne (V.G.), Institute of Medical Statistics and Epidemiology, Technical University Munich, Munich (R.B.), Klinikum Schwabing, Munich (C.M.W.), private oncology practice, Dresden (T.I.), Medical Department II, University of Schleswig-Holstein, City Hospital Kiel, Kiel (M.R., M.K.), the Department of Internal Medicine III, Ulm University, Ulm (S.S., H.D.), and Cluster of Excellence "Cellular Stress Responses in Aging-Associated Diseases" (CECAD), University of Cologne, Cologne (M.H.) - all in Germany; Penza Regional Oncology Dispensary, Penza (T.C.), and Regional Clinical Hospital N.A. Semashko, Nizhny Novgorod (O.S.) - both in Russia; Servicio De Hematologia, Hospital Universitario 12 De Octubre, Madrid (J.S.); Hôpital Haut Lévêque, Bordeaux, Pessac, France (M.-S.D.); the Department of Haematology, Monash Medical Centre, Clayton, Australia (S.O.); University of Calgary, Calgary, AB, Canada (C.J.O.); the Department of Immunology, Erasmus Medical Center Rotterdam, Rotterdam, the Netherlands (A.W.L.); F. Hoffmann-La Roche, Basel, Switzerland (E.A.); F. Hoffmann-La Roche, Welwyn, United Kingdom (K.H.); and Genentech, South San Francisco, CA (M.W.).

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http://dx.doi.org/10.1056/NEJMoa1313984DOI Listing
March 2014

Proposal for the clinical detection and management of patients and their family members with familial myelodysplastic syndrome/acute leukemia predisposition syndromes.

Leuk Lymphoma 2013 Jan 9;54(1):28-35. Epub 2012 Jul 9.

Section of Hematology/Oncology, Department of Medicine and Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA.

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http://www.tandfonline.com/doi/full/10.3109/10428194.2012.70
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http://dx.doi.org/10.3109/10428194.2012.701738DOI Listing
January 2013

Obinutuzumab for the treatment of lymphoproliferative disorders.

Expert Opin Biol Ther 2012 Mar 28;12(3):343-51. Epub 2012 Jan 28.

Tom Baker Cancer Centre & University of Calgary, 1331-29th St NW, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1517/14712598.2012.657622DOI Listing
March 2012

Upfront thiotepa, busulfan, cyclophosphamide, and autologous stem cell transplantation for primary CNS lymphoma: a single centre experience.

Leuk Lymphoma 2012 May 6;53(5):862-7. Epub 2011 Dec 6.

Department of Oncology and Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.3109/10428194.2011.633250DOI Listing
May 2012

Familial myelodysplastic syndromes: a review of the literature.

Haematologica 2011 Oct 23;96(10):1536-42. Epub 2011 May 23.

Division of Hematology and Hematologic Malignancies, Department of Medicine, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.3324/haematol.2011.043422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186316PMC
October 2011

Characterization of two carnation petal prolyl 4 hydroxylases.

Physiol Plant 2010 Oct;140(2):199-207

Department of Horticultural Genetics & Biotechnology, Mediterranean Agronomic Institute at Chania, Chania, Greece.

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http://dx.doi.org/10.1111/j.1399-3054.2010.01390.xDOI Listing
October 2010

The clinical relevance of Wilms Tumour 1 (WT1) gene mutations in acute leukaemia.

Hematol Oncol 2010 Mar;28(1):13-9

Division of Hematology and Hematological Malignancies, University of Calgary, 601A South Tower, Foothills Medical Centre, 1403-29th Street NW, Calgary, Alberta, T2N 2T9, Canada.

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http://doi.wiley.com/10.1002/hon.931
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http://dx.doi.org/10.1002/hon.931DOI Listing
March 2010

Insights into familial platelet disorder with propensity to myeloid malignancy (FPD/AML).

Authors:
Carolyn Owen

Leuk Res 2010 Feb 19;34(2):141-2. Epub 2009 Aug 19.

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http://dx.doi.org/10.1016/j.leukres.2009.07.037DOI Listing
February 2010

SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL.

Blood 2008 Jul 23;112(2):394-7. Epub 2008 Apr 23.

Hematology Division and Center for Cell-Based Therapy, Faculty of Medicine of Ribeirão Preto, University of São Paulo, São Paulo, Brazil.

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http://dx.doi.org/10.1182/blood-2007-11-124065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442748PMC
July 2008

Familial myelodysplasia and acute myeloid leukaemia--a review.

Br J Haematol 2008 Jan;140(2):123-32

Centre for Medical Oncology, Barts & the London School of Medicine & Dentistry, London, UK.

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http://dx.doi.org/10.1111/j.1365-2141.2007.06909.xDOI Listing
January 2008

Does this patient have deep vein thrombosis?

JAMA 2006 Jan;295(2):199-207

Department of Medicine, University of Ottawa, Ontario.

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.29
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http://dx.doi.org/10.1001/jama.295.2.199DOI Listing
January 2006

AFLP reveals structural details of genetic diversity within cultivated olive germplasm from the Eastern Mediterranean.

Theor Appl Genet 2005 May 18;110(7):1169-76. Epub 2004 Dec 18.

Department of Horticultural Genetics and Biotechnology, Mediterranean Agronomic Institute, Chania, 73100, Greece.

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http://dx.doi.org/10.1007/s00122-004-1861-zDOI Listing
May 2005

Effect on CD4 T-cell count of replacing protease inhibitors in patients with successful HIV suppression: a meta-analysis.

AIDS 2004 Mar;18(4):693-5

Department of Medicine, Ottawa Hospital, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1097/00002030-200403050-00016DOI Listing
March 2004

Catalytic asymmetric rearrangement of allylic N-aryl trifluoroacetimidates. A useful method for transforming prochiral allylic alcohols to chiral allylic amines.

Org Lett 2003 May;5(11):1809-12

Department of Chemistry, University of California, Irvine, 516 Rowland Hall, Irvine, California 92697-2025, USA.

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http://pubs.acs.org/doi/abs/10.1021/ol0271786
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http://dx.doi.org/10.1021/ol0271786DOI Listing
May 2003

JNK and ERK signaling pathways in multistage mouse carcinogenesis: studies in the inhibition of signaling cascades as a means to understand their in vivo biological role.

Anticancer Res 2002 Mar-Apr;22(2A):755-9

Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, Athens, Greece.

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June 2002

Characterization of two CTR-like protein kinases in Rosa hybrida and their expression during flower senescence and in response to ethylene.

J Exp Bot 2002 May;53(371):1223-5

Department of Agricultural Science, Horticulture, Royal Veterinary and Agricultural University, Thorvaldsensvej 40, DK-1871 Frederiksberg C, Denmark.

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http://dx.doi.org/10.1093/jexbot/53.371.1223DOI Listing
May 2002