Carolyn A Felix

Carolyn A Felix

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Carolyn A Felix

Carolyn A Felix

Publications by authors named "Carolyn A Felix"

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35Publications

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Unique Familial MLL(KMT2A)-Rearranged Precursor B-Cell Infant Acute Lymphoblastic Leukemia in Non-twin Siblings.

Pediatr Blood Cancer 2016 07 21;63(7):1175-80. Epub 2016 Mar 21.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/pbc.25957DOI Listing
July 2016

Topoisomerase II and leukemia.

Ann N Y Acad Sci 2014 Mar 3;1310:98-110. Epub 2014 Feb 3.

Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee.

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http://dx.doi.org/10.1111/nyas.12358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961513PMC
March 2014

Infant leukemia 2010: a call to action for the west and the "four Asian Tigers".

Authors:
Carolyn A Felix

Pediatr Blood Cancer 2010 Dec;55(7):1247-9

Division of Oncology, The Children's Hospital of Philadelphia, Department of Pediatrcs, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4318, USA.

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http://dx.doi.org/10.1002/pbc.22817DOI Listing
December 2010

A safer regimen for high-risk neuroblastoma.

Authors:
Carolyn A Felix

Pediatr Blood Cancer 2009 Jul;53(1):3-6

Division of Oncology, Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1002/pbc.22020DOI Listing
July 2009

Panhandle PCR approaches to cloning MLL genomic breakpoint junctions and fusion transcript sequences.

Methods Mol Biol 2009 ;538:85-114

Division of Oncology, Children's Hospital of Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/978-1-59745-418-6_6DOI Listing
May 2009

Abundant anti-apoptotic BCL-2 is a molecular target in leukaemias with t(4;11) translocation.

Br J Haematol 2008 Jun 18;141(6):827-39. Epub 2008 Apr 18.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/j.1365-2141.2008.07100.xDOI Listing
June 2008

Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome.

Blood 2008 Apr 14;111(7):3802-12. Epub 2008 Jan 14.

Division of Oncology, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine 19104-4318, USA.

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http://dx.doi.org/10.1182/blood-2007-07-096065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275033PMC
April 2008

Characterization of an etoposide-glutathione conjugate derived from metabolic activation by human cytochrome p450.

Curr Drug Metab 2006 Dec;7(8):897-911

Center for Cancer Pharmacology, University of Pennsylvania School of Medicine, 854 BRB II/III, 421 Curie Boulevard, Philadelphia, PA 19104-6160, USA.

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December 2006

Proteomics-based strategy to identify biomarkers and pharmacological targets in leukemias with t(4;11) translocations.

J Proteome Res 2006 Oct;5(10):2743-53

Center for Cancer Pharmacology, University of Pennsylvania School of Medicine, and Division of Oncology, The Children's Hospital of Philadelphia, Department of Pediatrics, Pennsylvania 19104-4318, USA.

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http://dx.doi.org/10.1021/pr060235vDOI Listing
October 2006

Topoisomerase II and the etiology of chromosomal translocations.

DNA Repair (Amst) 2006 Sep 20;5(9-10):1093-108. Epub 2006 Jul 20.

Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.dnarep.2006.05.031DOI Listing
September 2006

BglII-based panhandle and reverse panhandle PCR approaches increase capability for cloning der(II) and der(other) genomic breakpoint junctions of MLL translocations.

Genes Chromosomes Cancer 2006 Aug;45(8):740-53

Division of Oncology, The Children's Hospital of Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1002/gcc.20336DOI Listing
August 2006

Development of cold agglutinin autoimmune hemolytic anemia during treatment for pediatric acute lymphoblastic leukemia.

J Pediatr Hematol Oncol 2005 Jul;27(7):397-9

Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1097/01.mph.0000174031.63108.ebDOI Listing
July 2005

The molecular basis of leukemia.

Hematology Am Soc Hematol Educ Program 2004 :80-97

Brigham and Women's Hospital, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.

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http://www.asheducationbook.org/cgi/doi/10.1182/asheducation
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http://dx.doi.org/10.1182/asheducation-2004.1.80DOI Listing
April 2005

Therapy-related acute myeloid leukemia-like MLL rearrangements are induced by etoposide in primary human CD34+ cells and remain stable after clonal expansion.

Blood 2005 Mar 4;105(5):2124-31. Epub 2004 Nov 4.

Institute of Cancer Genetics, Department of Pathology, Columbia University College of Physicians and Surgeons, 1150 St Nicholas Ave, New York, NY, USA.

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http://dx.doi.org/10.1182/blood-2004-07-2683DOI Listing
March 2005

Maternal diet and infant leukemia: the DNA topoisomerase II inhibitor hypothesis: a report from the children's oncology group.

Cancer Epidemiol Biomarkers Prev 2005 Mar;14(3):651-5

Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-04-0602DOI Listing
March 2005

Kinetics and regulation of cytochrome P450-mediated etoposide metabolism.

Drug Metab Dispos 2004 Sep;32(9):993-1000

Center for Cancer Pharmacology, Department of Pharmacology, University of Pennsylvania School of Medicine, 421 Curie Boulevard, Philadelphia, PA 19104-6160, USA.

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September 2004

1,4-Benzoquinone is a topoisomerase II poison.

Biochemistry 2004 Jun;43(23):7563-74

Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146, USA.

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http://dx.doi.org/10.1021/bi049756rDOI Listing
June 2004

Plasma etoposide catechol increases in pediatric patients undergoing multiple-day chemotherapy with etoposide.

Clin Cancer Res 2004 May;10(9):2977-85

Center for Cancer Pharmacology, Department of Pharmacology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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May 2004

Low NAD(P)H:quinone oxidoreductase activity is associated with increased risk of leukemia with MLL translocations in infants and children.

Blood 2002 Dec 1;100(13):4590-3. Epub 2002 Aug 1.

Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley 94720-7360, USA.

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http://dx.doi.org/10.1182/blood-2001-12-0264DOI Listing
December 2002

Isolated extramedullary relapse in acute myeloid leukemia: A retrospective analysis.

Med Pediatr Oncol 2002 Jun;38(6):387-90

Division of Oncology, The Children's Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1002/mpo.10069DOI Listing
June 2002

Pediatric Acute Lymphoblastic Leukemia: Challenges and Controversies in 2000.

Hematology Am Soc Hematol Educ Program 2000 :285-302

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January 2000