Publications by authors named "Caroline Springer"

62Publications

Preclinical Evidence That Trametinib Enhances the Response to Antiangiogenic Tyrosine Kinase Inhibitors in Renal Cell Carcinoma.

Mol Cancer Ther 2016 Jan 20;15(1):172-83. Epub 2015 Oct 20.

Tumour Biology Team, The Breast Cancer Now Toby Robins Research Centre, Mary-Jean Mitchell Green Building, The Institute of Cancer Research (ICR), London, United Kingdom.

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January 2016

Detection of the prodrug-activating enzyme carboxypeptidase G2 activity with chemical exchange saturation transfer magnetic resonance.

Mol Imaging Biol 2014 Apr;16(2):152-7

Cancer Research UK and EPRSC Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK,

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April 2014

Bacterial-directed enzyme prodrug therapy.

J Control Release 2013 Aug 17;170(1):120-31. Epub 2013 May 17.

Cork Cancer Research Centre, Biosciences Institute, University College Cork, Cork, Ireland.

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August 2013

Potent BRAF kinase inhibitors based on 2,4,5-trisubstituted imidazole with naphthyl and benzothiophene 4-substituents.

Bioorg Med Chem 2013 Mar 3;21(5):1284-304. Epub 2013 Jan 3.

The Institute of Cancer Research, Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, 15 Cotswold Road, Sutton, Surrey SM2 5NG, United Kingdom.

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March 2013

BRAF as a therapeutic target: a patent review (2006 - 2012).

Expert Opin Ther Pat 2013 Feb 7;23(2):155-64. Epub 2013 Jan 7.

The Institute of Cancer Research, Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK.

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February 2013

Topical 5-fluorouracil elicits regressions of BRAF inhibitor-induced cutaneous squamous cell carcinoma.

J Invest Dermatol 2013 Jan 16;133(1):274-6. Epub 2012 Aug 16.

Seccio Dermatologia, Departament de Medicina, Hospital Universitari Vall d’Hebron, Universitat Autonomade Barcelona, Spain.

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January 2013

Small molecule inhibitors of BRAF in clinical trials.

Bioorg Med Chem Lett 2012 Jan 3;22(2):789-92. Epub 2011 Dec 3.

The Institute of Cancer Research, Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, 15 Cotswold Road, Sutton, Surrey SM2 5NG, United Kingdom.

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January 2012