Publications by authors named "Caroline Relton"

97Publications

Corrigendum to 'Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children' [Psychoneuroendocrinology 113 March (2020) 104484].

Psychoneuroendocrinology 2020 Nov 27;121:104829. Epub 2020 Aug 27.

Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA; Stanley Center for Psychiatric Research, The Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, 02115, USA; McCance Center for Brain Health at Massachusetts General Hospital, Boston, MA, 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.psyneuen.2020.104829DOI Listing
November 2020

DNA methylation signature of passive smoke exposure is less pronounced than active smoking: The Understanding Society study.

Environ Res 2020 Nov 31;190:109971. Epub 2020 Jul 31.

Population Health Sciences, Bristol Medical School, University of Bristol, BS8 2BN, UK; MRC Integrative Epidemiology Unit at University of Bristol, BS8 2BN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.envres.2020.109971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536273PMC
November 2020

Impact of sex hormone-binding globulin on the human phenome.

Hum Mol Genet 2020 Jul;29(11):1824-1832

Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1093/hmg/ddz269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372548PMC
July 2020

Impact of sex hormone-binding globulin on the human phenome.

Hum Mol Genet 2020 Jul;29(11):1824-1832

Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1093/hmg/ddz269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372548PMC
July 2020

Characterizing the Causal Pathway for Genetic Variants Associated with Neurological Phenotypes Using Human Brain-Derived Proteome Data.

Am J Hum Genet 2020 06 14;106(6):885-892. Epub 2020 May 14.

Medical Research Council (MRC) Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2020.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273531PMC
June 2020

DNA Methylation and Type 2 Diabetes: the Use of Mendelian Randomization to Assess Causality.

Curr Genet Med Rep 2019 Dec 15;7(4):191-207. Epub 2019 Nov 15.

MRC Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.

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http://dx.doi.org/10.1007/s40142-019-00176-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145450PMC
December 2019

The association of DNA methylation with body mass index: distinguishing between predictors and biomarkers.

Clin Epigenetics 2020 03 30;12(1):50. Epub 2020 Mar 30.

Medical Research Council Integrative Epidemiology Unit (MRC IEU), Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1186/s13148-020-00841-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106582PMC
March 2020

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age.

Genome Med 2020 03 2;12(1):25. Epub 2020 Mar 2.

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s13073-020-0716-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050134PMC
March 2020

Smoking, DNA Methylation, and Lung Function: a Mendelian Randomization Analysis to Investigate Causal Pathways.

Am J Hum Genet 2020 03 20;106(3):315-326. Epub 2020 Feb 20.

Medical Research Council Integrative Epidemiology Unit at the University of Bristol, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2020.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058834PMC
March 2020

Epigenomics of being bullied: changes in DNA methylation following bullying exposure.

Epigenetics 2020 Jun - Jul;15(6-7):750-764. Epub 2020 Jan 28.

Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC, University Medical Center Rotterdam , Rotterdam, The Netherlands.

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http://dx.doi.org/10.1080/15592294.2020.1719303DOI Listing
January 2020

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome.

Nat Commun 2020 01 10;11(1):185. Epub 2020 Jan 10.

MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1038/s41467-019-13921-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954187PMC
January 2020

Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children.

Psychoneuroendocrinology 2020 03 6;113:104484. Epub 2019 Nov 6.

Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA; Stanley Center for Psychiatric Research, The Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, 02115, USA; McCance Center for Brain Health at Massachusetts General Hospital, Boston, MA, 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.psyneuen.2019.104484DOI Listing
March 2020

Epigenome-wide association study of seizures in childhood and adolescence.

Clin Epigenetics 2020 01 8;12(1). Epub 2020 Jan 8.

Bristol Medical School, Population Health Sciences, University of Bristol, 5 Tyndall Avenue, Bristol, BS8 1UD, UK.

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http://dx.doi.org/10.1186/s13148-019-0793-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950851PMC
January 2020

Validation and characterisation of a DNA methylation alcohol biomarker across the life course.

Clin Epigenetics 2019 11 27;11(1):163. Epub 2019 Nov 27.

MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS82BN, UK.

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http://dx.doi.org/10.1186/s13148-019-0753-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880546PMC
November 2019

Epigenetics and gestational diabetes: a review of epigenetic epidemiology studies and their use to explore epigenetic mediation and improve prediction.

Diabetologia 2019 12 17;62(12):2171-2178. Epub 2019 Oct 17.

MRC Integrative Epidemiology Unit at the University of Bristol, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1007/s00125-019-05011-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861541PMC
December 2019

Serum cholesterol, MTHFR methylation, and symptoms of depression in children.

Dev Psychol 2019 Dec 17;55(12):2575-2586. Epub 2019 Oct 17.

Department of Psychology, Institute of Psychiatry, Psychology, and Neuroscience.

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http://dx.doi.org/10.1037/dev0000831DOI Listing
December 2019

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking.

Epigenomics 2019 10 19;11(13):1487-1500. Epub 2019 Sep 19.

Department of Health & Human Services, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.2217/epi-2019-0066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836223PMC
October 2019

An integrative approach to detect epigenetic mechanisms that putatively mediate the influence of lifestyle exposures on disease susceptibility.

Int J Epidemiol 2019 06;48(3):887-898

MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, UK.

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http://dx.doi.org/10.1093/ije/dyz119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659375PMC
June 2019

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

Authors:
Nicole M Warrington Robin N Beaumont Momoko Horikoshi Felix R Day Øyvind Helgeland Charles Laurin Jonas Bacelis Shouneng Peng Ke Hao Bjarke Feenstra Andrew R Wood Anubha Mahajan Jessica Tyrrell Neil R Robertson N William Rayner Zhen Qiao Gunn-Helen Moen Marc Vaudel Carmen J Marsit Jia Chen Michael Nodzenski Theresia M Schnurr Mohammad H Zafarmand Jonathan P Bradfield Niels Grarup Marjolein N Kooijman Ruifang Li-Gao Frank Geller Tarunveer S Ahluwalia Lavinia Paternoster Rico Rueedi Ville Huikari Jouke-Jan Hottenga Leo-Pekka Lyytikäinen Alana Cavadino Sarah Metrustry Diana L Cousminer Ying Wu Elisabeth Thiering Carol A Wang Christian T Have Natalia Vilor-Tejedor Peter K Joshi Jodie N Painter Ioanna Ntalla Ronny Myhre Niina Pitkänen Elisabeth M van Leeuwen Raimo Joro Vasiliki Lagou Rebecca C Richmond Ana Espinosa Sheila J Barton Hazel M Inskip John W Holloway Loreto Santa-Marina Xavier Estivill Wei Ang Julie A Marsh Christoph Reichetzeder Letizia Marullo Berthold Hocher Kathryn L Lunetta Joanne M Murabito Caroline L Relton Manolis Kogevinas Leda Chatzi Catherine Allard Luigi Bouchard Marie-France Hivert Ge Zhang Louis J Muglia Jani Heikkinen Camilla S Morgen Antoine H C van Kampen Barbera D C van Schaik Frank D Mentch Claudia Langenberg Jian'an Luan Robert A Scott Jing Hua Zhao Gibran Hemani Susan M Ring Amanda J Bennett Kyle J Gaulton Juan Fernandez-Tajes Natalie R van Zuydam Carolina Medina-Gomez Hugoline G de Haan Frits R Rosendaal Zoltán Kutalik Pedro Marques-Vidal Shikta Das Gonneke Willemsen Hamdi Mbarek Martina Müller-Nurasyid Marie Standl Emil V R Appel Cilius E Fonvig Caecilie Trier Catharina E M van Beijsterveldt Mario Murcia Mariona Bustamante Sílvia Bonas-Guarch David M Hougaard Josep M Mercader Allan Linneberg Katharina E Schraut Penelope A Lind Sarah E Medland Beverley M Shields Bridget A Knight Jin-Fang Chai Kalliope Panoutsopoulou Meike Bartels Friman Sánchez Jakob Stokholm David Torrents Rebecca K Vinding Sara M Willems Mustafa Atalay Bo L Chawes Peter Kovacs Inga Prokopenko Marcus A Tuke Hanieh Yaghootkar Katherine S Ruth Samuel E Jones Po-Ru Loh Anna Murray Michael N Weedon Anke Tönjes Michael Stumvoll Kim F Michaelsen Aino-Maija Eloranta Timo A Lakka Cornelia M van Duijn Wieland Kiess Antje Körner Harri Niinikoski Katja Pahkala Olli T Raitakari Bo Jacobsson Eleftheria Zeggini George V Dedoussis Yik-Ying Teo Seang-Mei Saw Grant W Montgomery Harry Campbell James F Wilson Tanja G M Vrijkotte Martine Vrijheid Eco J C N de Geus M Geoffrey Hayes Haja N Kadarmideen Jens-Christian Holm Lawrence J Beilin Craig E Pennell Joachim Heinrich Linda S Adair Judith B Borja Karen L Mohlke Johan G Eriksson Elisabeth E Widén Andrew T Hattersley Tim D Spector Mika Kähönen Jorma S Viikari Terho Lehtimäki Dorret I Boomsma Sylvain Sebert Peter Vollenweider Thorkild I A Sørensen Hans Bisgaard Klaus Bønnelykke Jeffrey C Murray Mads Melbye Ellen A Nohr Dennis O Mook-Kanamori Fernando Rivadeneira Albert Hofman Janine F Felix Vincent W V Jaddoe Torben Hansen Charlotta Pisinger Allan A Vaag Oluf Pedersen André G Uitterlinden Marjo-Riitta Järvelin Christine Power Elina Hyppönen Denise M Scholtens William L Lowe George Davey Smith Nicholas J Timpson Andrew P Morris Nicholas J Wareham Hakon Hakonarson Struan F A Grant Timothy M Frayling Debbie A Lawlor Pål R Njølstad Stefan Johansson Ken K Ong Mark I McCarthy John R B Perry David M Evans Rachel M Freathy

Nat Genet 2019 05 1;51(5):804-814. Epub 2019 May 1.

Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Royal Devon and Exeter Hospital, Exeter, UK.

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http://dx.doi.org/10.1038/s41588-019-0403-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522365PMC
May 2019

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Authors:
Leanne K Küpers Claire Monnereau Gemma C Sharp Paul Yousefi Lucas A Salas Akram Ghantous Christian M Page Sarah E Reese Allen J Wilcox Darina Czamara Anne P Starling Alexei Novoloaca Samantha Lent Ritu Roy Cathrine Hoyo Carrie V Breton Catherine Allard Allan C Just Kelly M Bakulski John W Holloway Todd M Everson Cheng-Jian Xu Rae-Chi Huang Diana A van der Plaat Matthias Wielscher Simon Kebede Merid Vilhelmina Ullemar Faisal I Rezwan Jari Lahti Jenny van Dongen Sabine A S Langie Tom G Richardson Maria C Magnus Ellen A Nohr Zongli Xu Liesbeth Duijts Shanshan Zhao Weiming Zhang Michelle Plusquin Dawn L DeMeo Olivia Solomon Joosje H Heimovaara Dereje D Jima Lu Gao Mariona Bustamante Patrice Perron Robert O Wright Irva Hertz-Picciotto Hongmei Zhang Margaret R Karagas Ulrike Gehring Carmen J Marsit Lawrence J Beilin Judith M Vonk Marjo-Riitta Jarvelin Anna Bergström Anne K Örtqvist Susan Ewart Pia M Villa Sophie E Moore Gonneke Willemsen Arnout R L Standaert Siri E Håberg Thorkild I A Sørensen Jack A Taylor Katri Räikkönen Ivana V Yang Katerina Kechris Tim S Nawrot Matt J Silver Yun Yun Gong Lorenzo Richiardi Manolis Kogevinas Augusto A Litonjua Brenda Eskenazi Karen Huen Hamdi Mbarek Rachel L Maguire Terence Dwyer Martine Vrijheid Luigi Bouchard Andrea A Baccarelli Lisa A Croen Wilfried Karmaus Denise Anderson Maaike de Vries Sylvain Sebert Juha Kere Robert Karlsson Syed Hasan Arshad Esa Hämäläinen Michael N Routledge Dorret I Boomsma Andrew P Feinberg Craig J Newschaffer Eva Govarts Matthieu Moisse M Daniele Fallin Erik Melén Andrew M Prentice Eero Kajantie Catarina Almqvist Emily Oken Dana Dabelea H Marike Boezen Phillip E Melton Rosalind J Wright Gerard H Koppelman Letizia Trevisi Marie-France Hivert Jordi Sunyer Monica C Munthe-Kaas Susan K Murphy Eva Corpeleijn Joseph Wiemels Nina Holland Zdenko Herceg Elisabeth B Binder George Davey Smith Vincent W V Jaddoe Rolv T Lie Wenche Nystad Stephanie J London Debbie A Lawlor Caroline L Relton Harold Snieder Janine F Felix

Nat Commun 2019 04 23;10(1):1893. Epub 2019 Apr 23.

The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41467-019-09671-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478731PMC
April 2019

Sensitive Periods for the Effect of Childhood Adversity on DNA Methylation: Results From a Prospective, Longitudinal Study.

Biol Psychiatry 2019 05 21;85(10):838-849. Epub 2019 Jan 21.

Medical Research Council Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom; Institute of Genetic Medicine, University of Newcastle, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2018.12.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552666PMC
May 2019

Response to: Prenatal smoke exposure, DNA methylation and a link between DRD1 and lung cancer.

Int J Epidemiol 2019 08;48(4):1378-1379

MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1093/ije/dyz036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830268PMC
August 2019

Using Openly Accessible Resources to Strengthen Causal Inference in Epigenetic Epidemiology of Neurodevelopment and Mental Health.

Genes (Basel) 2019 03 1;10(3). Epub 2019 Mar 1.

Medical Research Council Integrative Epidemiology Unit, University of Bristol, BS8 2BN Bristol, UK.

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http://dx.doi.org/10.3390/genes10030193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470715PMC
March 2019

Leveraging brain cortex-derived molecular data to elucidate epigenetic and transcriptomic drivers of complex traits and disease.

Transl Psychiatry 2019 02 28;9(1):105. Epub 2019 Feb 28.

MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1038/s41398-019-0437-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395652PMC
February 2019

Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization.

Genome Med 2019 01 31;11(1). Epub 2019 Jan 31.

MRC Integrative Epidemiology Unit, Bristol Medical School (Population Health Sciences), University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1186/s13073-019-0613-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354354PMC
January 2019

Differential methylation of the type 2 diabetes susceptibility locus KCNQ1 is associated with insulin sensitivity and is predicted by CpG site specific genetic variation.

Diabetes Res Clin Pract 2019 Feb 11;148:189-199. Epub 2019 Jan 11.

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 7RU, UK; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.diabres.2019.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395844PMC
February 2019

The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study.

Authors:
Mattias Johansson Robert Carreras-Torres Ghislaine Scelo Mark P Purdue Daniela Mariosa David C Muller Nicolas J Timpson Philip C Haycock Kevin M Brown Zhaoming Wang Yuanqing Ye Jonathan N Hofmann Matthieu Foll Valerie Gaborieau Mitchell J Machiela Leandro M Colli Peng Li Jean-Guillaume Garnier Helene Blanche Anne Boland Laurie Burdette Egor Prokhortchouk Konstantin G Skryabin Meredith Yeager Sanja Radojevic-Skodric Simona Ognjanovic Lenka Foretova Ivana Holcatova Vladimir Janout Dana Mates Anush Mukeriya Stefan Rascu David Zaridze Vladimir Bencko Cezary Cybulski Eleonora Fabianova Viorel Jinga Jolanta Lissowska Jan Lubinski Marie Navratilova Peter Rudnai Simone Benhamou Geraldine Cancel-Tassin Olivier Cussenot Elisabete Weiderpass Börje Ljungberg Raviprakash Tumkur Sitaram Christel Häggström Fiona Bruinsma Susan J Jordan Gianluca Severi Ingrid Winship Kristian Hveem Lars J Vatten Tony Fletcher Susanna C Larsson Alicja Wolk Rosamonde E Banks Peter J Selby Douglas F Easton Gabriella Andreotti Laura E Beane Freeman Stella Koutros Satu Männistö Stephanie Weinstein Peter E Clark Todd L Edwards Loren Lipworth Susan M Gapstur Victoria L Stevens Hallie Carol Matthew L Freedman Mark M Pomerantz Eunyoung Cho Kathryn M Wilson J Michael Gaziano Howard D Sesso Neal D Freedman Alexander S Parker Jeanette E Eckel-Passow Wen-Yi Huang Richard J Kahnoski Brian R Lane Sabrina L Noyes David Petillo Bin Tean Teh Ulrike Peters Emily White Garnet L Anderson Lisa Johnson Juhua Luo Julie Buring I-Min Lee Wong-Ho Chow Lee E Moore Timothy Eisen Marc Henrion James Larkin Poulami Barman Bradley C Leibovich Toni K Choueiri G Mark Lathrop Jean-Francois Deleuze Marc Gunter James D McKay Xifeng Wu Richard S Houlston Stephen J Chanock Caroline Relton J Brent Richards Richard M Martin George Davey Smith Paul Brennan

PLoS Med 2019 01 3;16(1):e1002724. Epub 2019 Jan 3.

International Agency for Research on Cancer (IARC), Lyon, France.

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http://dx.doi.org/10.1371/journal.pmed.1002724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317776PMC
January 2019

Epigenome-wide meta-analysis of DNA methylation and childhood asthma.

J Allergy Clin Immunol 2019 06 21;143(6):2062-2074. Epub 2018 Dec 21.

Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183278
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http://dx.doi.org/10.1016/j.jaci.2018.11.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556405PMC
June 2019

Associations of sex hormone-binding globulin and testosterone with genome-wide DNA methylation.

BMC Genet 2018 12 14;19(1):113. Epub 2018 Dec 14.

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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https://bmcgenet.biomedcentral.com/articles/10.1186/s12863-0
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http://dx.doi.org/10.1186/s12863-018-0703-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295101PMC
December 2018

Maternal smoking during pregnancy and autism: using causal inference methods in a birth cohort study.

Transl Psychiatry 2018 11 29;8(1):262. Epub 2018 Nov 29.

National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and the University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1038/s41398-018-0313-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265272PMC
November 2018

Use of Mendelian andomization for dentifying isk actors for rain umors.

Front Genet 2018 12;9:525. Epub 2018 Nov 12.

Brain Tumour Research Centre, Institute of Clinical Neurosciences, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.3389/fgene.2018.00525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240585PMC
November 2018

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults.

EBioMedicine 2018 Dec 13;38:206-216. Epub 2018 Nov 13.

Center for Life Course Health Research, University of Oulu, Oulu, Finland; Biocenter Oulu, University of Oulu, Oulu, Finland; Medical Research Centre (MRC) Oulu, Oulu University Hospital, University of Oulu, Oulu, Finland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23523964183048
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http://dx.doi.org/10.1016/j.ebiom.2018.10.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306313PMC
December 2018

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study.

Cancer Epidemiol Biomarkers Prev 2019 01 23;28(1):208-216. Epub 2018 Oct 23.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.

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http://cebp.aacrjournals.org/lookup/doi/10.1158/1055-9965.EP
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http://dx.doi.org/10.1158/1055-9965.EPI-18-0079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746173PMC
January 2019

Maternal Red Blood Cell Folate and Infant Vitamin B Status Influence Methylation of Genes Associated with Childhood Acute Lymphoblastic Leukemia.

Mol Nutr Food Res 2018 11 11;62(22):e1800411. Epub 2018 Oct 11.

Faculty of Health and Life Sciences, Department of Applied Sciences, Northumbria University, Newcastle upon Tyne, NE1 8SG, UK.

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http://dx.doi.org/10.1002/mnfr.201800411DOI Listing
November 2018

Assessing the Role of DNA Methylation-Derived Neutrophil-to-Lymphocyte Ratio in Rheumatoid Arthritis.

J Immunol Res 2018 14;2018:2624981. Epub 2018 Aug 14.

MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1155/2018/2624981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112073PMC
November 2018

Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes.

J Autoimmun 2018 09 29;93:66-75. Epub 2018 Jun 29.

MRC Integrative Epidemiology Unit, Bristol Medical School (Population Health Sciences), University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S08968411183020
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http://dx.doi.org/10.1016/j.jaut.2018.06.005DOI Listing
September 2018

Do Depression and Stressful Events Cause Premature Aging?

Am J Psychiatry 2018 08;175(8):714-715

From the Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, U.K.; and the School of Social and Community Medicine, University of Bristol, Clifton, U.K.

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http://dx.doi.org/10.1176/appi.ajp.2018.18050618DOI Listing
August 2018

Causal Inference in Cancer Epidemiology: What Is the Role of Mendelian Randomization?

Cancer Epidemiol Biomarkers Prev 2018 09 25;27(9):995-1010. Epub 2018 Jun 25.

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-17-1177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522350PMC
September 2018

Systematic Mendelian randomization framework elucidates hundreds of CpG sites which may mediate the influence of genetic variants on disease.

Hum Mol Genet 2018 09;27(18):3293-3304

MRC Integrative Epidemiology Unit (IEU), Bristol Medical School (Population Health Sciences), University of Bristol, Oakfield House, Oakfield Grove, Bristol, UK.

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http://dx.doi.org/10.1093/hmg/ddy210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121186PMC
September 2018

DNA methylation as a marker for prenatal smoke exposure in adults.

Int J Epidemiol 2018 08;47(4):1120-1130

MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1093/ije/dyy091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124615PMC
August 2018

Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception.

Epigenetics Chromatin 2018 05 30;11(1):25. Epub 2018 May 30.

Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.

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http://dx.doi.org/10.1186/s13072-018-0191-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975493PMC
May 2018

Role of obesity in smoking behaviour: Mendelian randomisation study in UK Biobank.

BMJ 2018 May 16;361:k1767. Epub 2018 May 16.

Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953237PMC
http://dx.doi.org/10.1136/bmj.k1767DOI Listing
May 2018

Longitudinal analysis strategies for modelling epigenetic trajectories.

Int J Epidemiol 2018 04;47(2):516-525

MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1093/ije/dyy012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913606PMC
April 2018

Exploring the utility of alcohol flushing as an instrumental variable for alcohol intake in Koreans.

Sci Rep 2018 01 11;8(1):458. Epub 2018 Jan 11.

Department of Public Health Sciences, BK21PLUS Program in Embodiment: Health-Society Interaction, Graduate School, Korea University, Seoul, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-017-18856-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765011PMC
January 2018

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics.

Hum Mol Genet 2018 02;27(4):742-756

Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK.

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http://dx.doi.org/10.1093/hmg/ddx429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886200PMC
February 2018