Caroline F Thorn

Caroline F Thorn

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Caroline F Thorn

Caroline F Thorn

Publications by authors named "Caroline F Thorn"

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PharmGKB summary: clozapine pathway, pharmacokinetics.

Pharmacogenet Genomics 2018 09;28(9):214-222

Departments of Biomedical Data Sciences.

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http://dx.doi.org/10.1097/FPC.0000000000000347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449846PMC
September 2018

PharmGKB summary: pazopanib pathway, pharmacokinetics.

Pharmacogenet Genomics 2017 08;27(8):307-312

Departments of aBiomedical Data Sciences bBiomedical Engineering cGenetics, Stanford University, Stanford, California dDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862561PMC
August 2017

PharmGKB summary: isoniazid pathway, pharmacokinetics.

Pharmacogenet Genomics 2016 09;26(9):436-44

Departments of aGenetics bBioengineering, Stanford University, Stanford cKeck School of Medicine of University of Southern California, Los Angeles, California, USA dDepartment of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece eDepartment of Pharmacology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1097/FPC.0000000000000232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970941PMC
September 2016

PharmGKB summary: pathways of acetaminophen metabolism at the therapeutic versus toxic doses.

Pharmacogenet Genomics 2015 Aug;25(8):416-26

aDepartment of Systems Pharmacology and Translational Therapeutics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Departments of bGenetics cBioengineering, Stanford University Medical Center, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498995PMC
August 2015

PharmGKB summary: ibuprofen pathways.

Pharmacogenet Genomics 2015 Feb;25(2):96-106

aDepartment of Systems Pharmacology and Translational Therapeutics bInstitute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Departments of cGenetics dBioengineering, Stanford University, Stanford, California, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/FPC.0000000000000113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355401PMC
February 2015

PharmGKB summary: gemcitabine pathway.

Pharmacogenet Genomics 2014 Nov;24(11):564-74

Departments of aGenetics bBioengineering, Stanford University, Stanford, California, USA cDepartment of Pharmacotherapy and Translational Research dCenter for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, Florida eDepartment of Molecular Pharmacology & Experimental Therapeutics, Division of Clinical Pharmacology, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189987PMC
November 2014

PharmGKB summary: uric acid-lowering drugs pathway, pharmacodynamics.

Pharmacogenet Genomics 2014 Sep;24(9):464-76

Departments of aGenetics bBioengineering, Stanford University, Stanford, California cACOS for Research, Department of Veterans Affairs Medical Center Departments of dMedicine ePharmacology/Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/FPC.0000000000000058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122637PMC
September 2014

PharmGKB: the Pharmacogenomics Knowledge Base.

Methods Mol Biol 2013 ;1015:311-20

Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.1007/978-1-62703-435-7_20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084821PMC
February 2014

PharmGKB summary: ifosfamide pathways, pharmacokinetics and pharmacodynamics.

Pharmacogenet Genomics 2014 Feb;24(2):133-8

Departments of aGenetics bBioengineering, Stanford University Medical Center, Stanford, California cDepartments of Medicine, Indiana University Simon Cancer Center, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084804PMC
February 2014

PharmGKB summary: tamoxifen pathway, pharmacokinetics.

Pharmacogenet Genomics 2013 Nov;23(11):643-7

Departments of aGenetics bBioengineering, Stanford University Medical Center, Stanford, California cDepartment of Medicine, Indiana University Simon Cancer Center, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1097/FPC.0b013e3283656bc1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084801PMC
November 2013

PharmGKB summary: Diuretics pathway, pharmacodynamics.

Pharmacogenet Genomics 2013 Aug;23(8):449-53

Department of Genetics, Stanford University Medical Center, Stanford, California 94305-5120, USA.

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http://dx.doi.org/10.1097/FPC.0b013e3283636822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084786PMC
August 2013

Valproic acid pathway: pharmacokinetics and pharmacodynamics.

Pharmacogenet Genomics 2013 Apr;23(4):236-41

Department of Experimental and Clinical Pharmacology, University of Minnesota-Twin Cities, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32835ea0b2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696515PMC
April 2013

PharmGKB summary: very important pharmacogene information for GSTT1.

Pharmacogenet Genomics 2012 Aug;22(8):646-51

Department of Genetics, Stanford University Medical Center, Stanford, California, USA.

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http://dx.doi.org/10.1097/FPC.0b013e3283527c02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395771PMC
August 2012

Using ODIN for a PharmGKB revalidation experiment.

Database (Oxford) 2012 23;2012:bas021. Epub 2012 Apr 23.

Institute of Computational Linguistics, Binzmuhlestrasse 171, 8050 Zurich, Switzerland.

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http://dx.doi.org/10.1093/database/bas021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332569PMC
June 2012

PharmGKB summary: phenytoin pathway.

Pharmacogenet Genomics 2012 Jun;22(6):466-70

Department of Genetics, Stanford University Medical Center, Stanford, California, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32834aeedbDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349446PMC
June 2012

PharmGKB summary: caffeine pathway.

Pharmacogenet Genomics 2012 May;22(5):389-95

Department of Genetics, Stanford University Medical Center, Stanford, California 94305-5120, USA.

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http://dx.doi.org/10.1097/FPC.0b013e3283505d5eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381939PMC
May 2012

Celecoxib pathways: pharmacokinetics and pharmacodynamics.

Pharmacogenet Genomics 2012 Apr;22(4):310-8

Department of Genetics, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32834f94cbDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303994PMC
April 2012

PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19.

Pharmacogenet Genomics 2012 Feb;22(2):159-65

Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32834d4962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349992PMC
February 2012

PharmGKB summary: very important pharmacogene information for CYP1A2.

Pharmacogenet Genomics 2012 Jan;22(1):73-7

Department of Genetics, Stanford University Medical Center, Stanford, California 94305-5120, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32834c6efdDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346273PMC
January 2012

PharmGKB summary: carbamazepine pathway.

Pharmacogenet Genomics 2011 Dec;21(12):906-10

Department of Genetics, Stanford University Medical Center, Stanford, California 94305-5120, USA.

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https://insights.ovid.com/crossref?an=01213011-201112000-000
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http://dx.doi.org/10.1097/FPC.0b013e328348c6f2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349991PMC
December 2011

PharmGKB summary: very important pharmacogene information for PTGS2.

Pharmacogenet Genomics 2011 Sep;21(9):607-13

Department of Genetics, Stanford University Medical Center, Stanford, California 94305-5120, USA.

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http://dx.doi.org/10.1097/FPC.0b013e3283415515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141084PMC
September 2011

Doxorubicin pathways: pharmacodynamics and adverse effects.

Pharmacogenet Genomics 2011 Jul;21(7):440-6

Departments of Genetics, Stanford University Medical Center, California 94305-5120, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32833ffb56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116111PMC
July 2011

PharmGKB summary: fluoropyrimidine pathways.

Pharmacogenet Genomics 2011 Apr;21(4):237-42

Department of Genetics, Stanford University Medical Center, Stanford, California, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32833c6107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098754PMC
April 2011

KCNH2 pharmacogenomics summary.

Pharmacogenet Genomics 2010 Dec;20(12):775-7

Department of Genetics, Stanford University bBioengineering, Stanford University Medical Center, Stanford, California 94305-5120, USA.

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http://dx.doi.org/10.1097/FPC.0b013e3283349e9cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086352PMC
December 2010

PharmGKB summary: very important pharmacogene information for CYP2B6.

Pharmacogenet Genomics 2010 Aug;20(8):520-3

Department of Genetics, Stanford University Medical Center, Stanford, California 94305-5120, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086041PMC
August 2010

Pharmacogenomics and bioinformatics: PharmGKB.

Pharmacogenomics 2010 Apr;11(4):501-5

Department of Genetics, Stanford University Medical Center, Stanford, CA 94305-5120, USA.

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http://dx.doi.org/10.2217/pgs.10.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098752PMC
April 2010

PharmGKB summary: very important pharmacogene information for angiotensin-converting enzyme.

Pharmacogenet Genomics 2010 Feb;20(2):143-6

Department of Genetics, Stanford University Medical Center, Stanford, CA 94305-5120, USA.

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http://dx.doi.org/10.1097/FPC.0b013e3283339bf3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098760PMC
February 2010

Codeine and morphine pathway.

Pharmacogenet Genomics 2009 Jul;19(7):556-8

Department of Genetics, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32832e0eacDOI Listing
July 2009

Cytotoxic doses of ketoconazole affect expression of a subset of hepatic genes.

J Toxicol Environ Health A 2007 Nov;70(22):1946-55

Center for Biologics Research, Biologics and Genetic Therapies Directorate, Health Canada, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1080/15287390701551407DOI Listing
November 2007

Warfarin and cytochrome P450 2C9 genotype: possible ethnic variation in warfarin sensitivity.

Pharmacogenomics 2007 Mar;8(3):217-25

University of Pennsylvania, Department of Pharmacology and Center for Pharmacogenetics, School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.2217/14622416.8.3.217DOI Listing
March 2007

PharmGKB: the pharmacogenetics and pharmacogenomics knowledge base.

Methods Mol Biol 2005 ;311:179-91

Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1385/1-59259-957-5:179DOI Listing
November 2005

A statistical approach to scanning the biomedical literature for pharmacogenetics knowledge.

J Am Med Inform Assoc 2005 Mar-Apr;12(2):121-9. Epub 2004 Nov 23.

Section of Medical Informatics, MSOB X-215, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1197/jamia.M1640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC551544PMC
March 2005

TGF-beta down-regulates IL-1alpha-induced TLR2 expression in murine hepatocytes.

J Leukoc Biol 2004 Jun 23;75(6):1056-61. Epub 2004 Mar 23.

Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, Japan.

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http://dx.doi.org/10.1189/jlb.0104108DOI Listing
June 2004

TGF-β down-regulates IL-1α-induced TLR2 expression in murine hepatocytes.

J Leukoc Biol 2004 Jun;75(6):1056-1061

Department of Molecular Health Sciences, Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan.

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http://doi.wiley.com/10.1189/jlb.0104108
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http://dx.doi.org/10.1189/jlb.0104108DOI Listing
June 2004

A common ABCC2 promoter polymorphism is not a determinant of the risk of spina bifida.

Birth Defects Res A Clin Mol Teratol 2004 Jun;70(6):396-9

Department of Pharmacology and Center for Pharmacogenetics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1002/bdra.20023DOI Listing
June 2004

Tissue-specific regulation of the human acute-phase serum amyloid A genes, SAA1 and SAA2, by glucocorticoids in hepatic and epithelial cells.

Eur J Immunol 2003 Sep;33(9):2630-9

Department of Pharmacology and Center for Pharmacogenetics, University of Pennsylvania School of Medicine, Philadelphia 19104, USA.

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http://dx.doi.org/10.1002/eji.200323985DOI Listing
September 2003

Differential transcription of the mouse acute phase serum amyloid A genes in response to pro-inflammatory cytokines.

Amyloid 2002 Dec;9(4):229-36

Department of Pharmacology, Center for Pharmacogenetics, University of Pennsylvania School of Medicine, 159 Johnson Pavilion, 3620 Hamilton Walk, Philadelphia, PA 19104, USA.

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December 2002

Differential glucocorticoid enhancement of the cytokine-driven transcriptional activation of the human acute phase serum amyloid A genes, SAA1 and SAA2.

J Immunol 2002 Jul;169(1):399-406

Department of Pharmacology and Center for Pharmacogenetics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.169.1.399DOI Listing
July 2002