Publications by authors named "Caroline B M Porter"

12Publications

A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-Seq.

Mol Ther 2020 Jul 25. Epub 2020 Jul 25.

Cellular Immunotherapy Program and Cancer Center, Massachusetts General Hospital, Charlestown, MA 02129, USA; Harvard Medical School, Boston, MA 02115, USA; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02139, USA; Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2020.07.023DOI Listing
July 2020

Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses.

Immunity 2019 10;51(4):696-708.e9

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02114, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613193037
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http://dx.doi.org/10.1016/j.immuni.2019.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991097PMC
October 2019

Author Correction: Design, execution, and analysis of CRISPR-Cas9-based deletions and genetic interaction networks in the fungal pathogen Candida albicans.

Nat Protoc 2019 Aug;14(8):2595

Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.

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http://dx.doi.org/10.1038/s41596-019-0157-3DOI Listing
August 2019

Design, execution, and analysis of CRISPR-Cas9-based deletions and genetic interaction networks in the fungal pathogen Candida albicans.

Nat Protoc 2019 03 8;14(3):955-975. Epub 2019 Feb 8.

Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.

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http://dx.doi.org/10.1038/s41596-018-0122-6DOI Listing
March 2019

A CRISPR-Cas9-based gene drive platform for genetic interaction analysis in Candida albicans.

Nat Microbiol 2018 Jan 23;3(1):73-82. Epub 2017 Oct 23.

Department of Biological Engineering, Institute for Medical Engineering and Science, Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.

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http://dx.doi.org/10.1038/s41564-017-0043-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832965PMC
January 2018

Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control.

Cell Chem Biol 2017 Feb 19;24(2):195-206. Epub 2017 Jan 19.

Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA; Department of Biological Engineering, Institute for Medical Engineering & Science, Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard-MIT Program, Health Sciences and Technology, Cambridge, MA 02139, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2016.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426816PMC
February 2017

Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage.

Cell Rep 2015 Nov 22;13(5):968-80. Epub 2015 Oct 22.

Institute for Medical Engineering & Science, Department of Biological Engineering, and Synthetic Biology Center, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, 3 Blackfan Circle, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.09.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648786PMC
November 2015

Antibiotic efficacy is linked to bacterial cellular respiration.

Proc Natl Acad Sci U S A 2015 Jul 22;112(27):8173-80. Epub 2015 Jun 22.

Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115; Institute for Medical Engineering & Science, Department of Biological Engineering, and Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA 02139; Broad Institute of MIT and Harvard, Cambridge, MA 02139; Harvard-MIT Program in Health Sciences and Technology, Cambridge, MA 02139

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http://dx.doi.org/10.1073/pnas.1509743112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500273PMC
July 2015