Carmen Martin-Ruiz

Carmen Martin-Ruiz

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Carmen Martin-Ruiz

Carmen Martin-Ruiz

Publications by authors named "Carmen Martin-Ruiz"

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62Publications

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A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Nat Commun 2019 Aug 14;10(1):3669. Epub 2019 Aug 14.

NHLBI's and Boston University's Framingham Heart Study, Framingham, MA, 01702, USA.

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http://dx.doi.org/10.1038/s41467-019-11558-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694136PMC
August 2019

Peripheral inflammation in mild cognitive impairment with possible and probable Lewy body disease and Alzheimer's disease.

Int Psychogeriatr 2019 04 11;31(4):551-560. Epub 2019 Mar 11.

Institute of Neuroscience, Campus for Ageing and Vitality,Newcastle University,Newcastle upon Tyne,UK.

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http://dx.doi.org/10.1017/S1041610218001126DOI Listing
April 2019

Telomere length is associated with childhood trauma in patients with severe mental disorders.

Transl Psychiatry 2019 03 21;9(1):97. Epub 2019 Mar 21.

NORMENT K.G Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1038/s41398-019-0432-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428889PMC
March 2019

Plasma Vitamin B12, Supplementation and Mortality.

J Gerontol A Biol Sci Med Sci 2019 01;74(1):138

Faculty of Medical Sciences, Institute of Cellular Medicine, Newcastle upon Tyne.

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http://dx.doi.org/10.1093/gerona/gly200DOI Listing
January 2019

Peripheral inflammation in prodromal Alzheimer's and Lewy body dementias.

J Neurol Neurosurg Psychiatry 2018 04 16;89(4):339-345. Epub 2017 Dec 16.

Institute of Neuroscience, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1136/jnnp-2017-317134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869446PMC
April 2018

Homocysteine, Tryptophan, and Cognition in the Very Old.

J Am Med Dir Assoc 2017 10 23;18(10):895-896. Epub 2017 Aug 23.

School of Agriculture Food and Rural Development, Newcastle University, Newcastle-upon-Tyne, United Kingdom; Newcastle University Institute for Aging, Newcastle-upon-Tyne, United Kingdom; Human Nutrition Research Center, Newcastle University, Newcastle-upon-Tyne, United Kingdom; Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom.

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http://dx.doi.org/10.1016/j.jamda.2017.07.010DOI Listing
October 2017

One-Carbon Metabolism Biomarkers and Cognitive Decline in the Very Old: The Newcastle 85+ Study.

J Am Med Dir Assoc 2017 Sep 21;18(9):806.e19-806.e27. Epub 2017 Jun 21.

School of Agriculture, Food, and Rural Development, Newcastle University, Newcastle-upon-Tyne, UK; Newcastle University Institute for Ageing, Newcastle-upon-Tyne, UK; Human Nutrition Research Centre, Newcastle University, Newcastle-upon-Tyne, UK; Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, UK.

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http://dx.doi.org/10.1016/j.jamda.2017.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576913PMC
September 2017

Serum Thyroid Function, Mortality and Disability in Advanced Old Age: The Newcastle 85+ Study.

J Clin Endocrinol Metab 2016 11 23;101(11):4385-4394. Epub 2016 Aug 23.

Institute of Genetic Medicine (S.H.S.P., S.R.), Newcastle University, Newcastle upon Tyne NE1 3BZ, United Kingdom; Institute of Health and Society (M.E.Y., C.M.-R., A.K., J.C., T.B.K., C.J.), Newcastle University, Newcastle upon Tyne NE2 4AX, United Kingdom; and Department of Internal Medicine (T.J.V.), Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2016-1935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095241PMC
November 2016

Brood size moderates associations between relative size, telomere length, and immune development in European starling nestlings.

Ecol Evol 2016 Nov 17;6(22):8138-8148. Epub 2016 Oct 17.

Institute of Neuroscience and Centre for Behaviour & Evolution Newcastle University Henry Wellcome Building Newcastle UK.

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http://dx.doi.org/10.1002/ece3.2551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108265PMC
November 2016

Intakes of Folate and Vitamin B12 and Biomarkers of Status in the Very Old: The Newcastle 85+ Study.

Nutrients 2016 Sep 28;8(10). Epub 2016 Sep 28.

School of Agriculture Food and Rural Development, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.

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http://dx.doi.org/10.3390/nu8100604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083992PMC
September 2016

Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921.

Mech Ageing Dev 2016 Mar 10;154:43-8. Epub 2016 Feb 10.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK; Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK.

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http://dx.doi.org/10.1016/j.mad.2016.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798845PMC
March 2016

Age-related frailty and its association with biological markers of ageing.

BMC Med 2015 Jul 13;13:161. Epub 2015 Jul 13.

Institute for Cell and Molecular Biosciences and Newcastle University Institute for Ageing, Newcastle upon Tyne, NE4 5PL, UK.

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http://dx.doi.org/10.1186/s12916-015-0400-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499935PMC
July 2015

Neuropathologically mixed Alzheimer's and Lewy body disease: burden of pathological protein aggregates differs between clinical phenotypes.

Acta Neuropathol 2015 May 11;129(5):729-48. Epub 2015 Mar 11.

Institute of Neuroscience and Institute for Ageing, Newcastle University, Campus for Ageing and Vitality, NE4 5PL, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1007/s00401-015-1406-3DOI Listing
May 2015

Myocardial ischemia and reperfusion leads to transient CD8 immune deficiency and accelerated immunosenescence in CMV-seropositive patients.

Circ Res 2015 Jan 10;116(1):87-98. Epub 2014 Nov 10.

From the Institute of Genetic Medicine (J.H., E.V.S., S.E.B., S.M., B.K., I.S.), Institute of Aging and Health (C.M.-R., T.v.Z.), and Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom (A.B., M.E., R.D., S.T.), Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, United Kingdom (A.B., M.E., R.D., I.S.); Flow Cytometry Core Facility, International Center for Life, Newcastle upon Tyne, United Kingdom (I.D.); Department of Immunology, Institute of Medical Microbiology and Hygiene, Freiburg University, Germany (H.P.); CLIP-Childhood Leukaemia Investigation Prague, Department of Paediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic (K.F.); University Hospital Motol, Prague, Czech Republic (K.F.); Institute of Cardiovascular Sciences, The University of Manchester, United Kingdom (B.K.); and Department of Applied Sciences, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, United Kingdom (S.M., S.T.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.116.30439
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http://dx.doi.org/10.1161/CIRCRESAHA.116.304393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280279PMC
January 2015

Rate of telomere shortening and cardiovascular damage: a longitudinal study in the 1946 British Birth Cohort.

Eur Heart J 2014 Dec 22;35(46):3296-303. Epub 2014 Jun 22.

Vascular Physiology Unit, Institute of Cardiovascular Science, University College London, London, UK National Centre for Cardiovascular Prevention and Outcomes, University College London, 170 Tottenham Court Road, W1T 7HA London, UK

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http://dx.doi.org/10.1093/eurheartj/ehu226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258223PMC
December 2014

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

Hum Mol Genet 2014 Aug 31;23(16):4420-32. Epub 2014 Mar 31.

Department of Molecular Epidemiology, Netherlands Consortium for Healthy Ageing,

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http://dx.doi.org/10.1093/hmg/ddu139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103672PMC
August 2014

Biomarkers of healthy ageing: expectations and validation.

Proc Nutr Soc 2014 Aug 9;73(3):422-9. Epub 2014 May 9.

Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality,Newcastle upon Tyne NE4 5PL,UK.

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http://www.journals.cambridge.org/abstract_S0029665114000147
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http://dx.doi.org/10.1017/S0029665114000147DOI Listing
August 2014

Inflammation, telomere length, and grip strength: a 10-year longitudinal study.

Calcif Tissue Int 2014 Jul 25;95(1):54-63. Epub 2014 May 25.

MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD, UK.

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http://dx.doi.org/10.1007/s00223-014-9862-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098723PMC
July 2014

Frailty and mortality are not influenced by mitochondrial DNA haplotypes in the very old.

Neurobiol Aging 2013 Dec 30;34(12):2889.e1-4. Epub 2013 Apr 30.

Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906612PMC
December 2013

Telomere length and aging biomarkers in 70-year-olds: the Lothian Birth Cohort 1936.

Neurobiol Aging 2012 Jul 30;33(7):1486.e3-8. Epub 2010 Dec 30.

Centre for Cognitive Ageing and Cognitive Epidemiology, Medical Genetics Section, University of Edinburgh, Edinburgh, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S01974580100049
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http://dx.doi.org/10.1016/j.neurobiolaging.2010.11.013DOI Listing
July 2012

Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: cross-sectional findings from the Newcastle 85+ Study.

Mech Ageing Dev 2012 Jun 1;133(6):456-66. Epub 2012 Jun 1.

Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, United Kingdom.

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http://dx.doi.org/10.1016/j.mad.2012.05.005DOI Listing
June 2012

A senescent cell bystander effect: senescence-induced senescence.

Aging Cell 2012 Apr 9;11(2):345-9. Epub 2012 Feb 9.

Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1111/j.1474-9726.2012.00795.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488292PMC
April 2012

Telomere length and anaemia in old age: results from the Newcastle 85-plus Study and the Leiden 85-plus Study.

Age Ageing 2011 Jul 27;40(4):494-500. Epub 2011 May 27.

Department of Public Health and Primary Care, Leiden University Medical Centre, The Netherlands.

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http://dx.doi.org/10.1093/ageing/afr048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114621PMC
July 2011

DNA damage response and cellular senescence in tissues of aging mice.

Aging Cell 2009 Jun 9;8(3):311-23. Epub 2009 Apr 9.

Ageing Research Laboratories, Institute for Ageing and Health and Center for Integrated Systems Biology of Ageing and Nutrition (CISBAN), Newcastle University, Newcastle upon Tyne NE4 6BE, UK.

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http://doi.wiley.com/10.1111/j.1474-9726.2009.00481.x
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http://dx.doi.org/10.1111/j.1474-9726.2009.00481.xDOI Listing
June 2009

Premature senescence of mesothelial cells is associated with non-telomeric DNA damage.

Biochem Biophys Res Commun 2007 Oct 20;362(3):707-11. Epub 2007 Aug 20.

Department of Pathophysiology, University of Medical Sciences, Swiecickiego 6, 60781 Poznan, Poland.

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http://dx.doi.org/10.1016/j.bbrc.2007.08.047DOI Listing
October 2007

No association between socio-economic status and white blood cell telomere length.

Aging Cell 2007 Feb 5;6(1):125-8. Epub 2006 Dec 5.

Institute of Health and Society, Newcastle University, 21 Claremont Place, Newcastle upon Tyne NE2 4AA, UK.

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http://dx.doi.org/10.1111/j.1474-9726.2006.00258.xDOI Listing
February 2007

Telomere length is associated with left ventricular function in the oldest old: the Newcastle 85+ study.

Eur Heart J 2007 Jan 10;28(2):172-6. Epub 2007 Jan 10.

Institute for Ageing and Health, Newcastle University, and Department of Cardiology, Freeman Hospital, Newcastle-upon-Tyne, UK.

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http://dx.doi.org/10.1093/eurheartj/ehl437DOI Listing
January 2007

Telomere length predicts poststroke mortality, dementia, and cognitive decline.

Ann Neurol 2006 Aug;60(2):174-80

Institute for Ageing and Health, Newcastle General Hospital, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/ana.20869DOI Listing
August 2006

Extended lifespan and long telomeres in rectal fibroblasts from late-onset ulcerative colitis patients.

Eur J Gastroenterol Hepatol 2006 Feb;18(2):133-41

Department of Biological Sciences, University of Warwick, Coventry, UK.

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http://dx.doi.org/10.1097/00042737-200602000-00005DOI Listing
February 2006

Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: a population-based study.

Aging Cell 2005 Dec;4(6):287-90

Henry Wellcome Biogerontology Research Laboratory, University of Newcastle, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1111/j.1474-9726.2005.00171.xDOI Listing
December 2005

Stochastic variation in telomere shortening rate causes heterogeneity of human fibroblast replicative life span.

J Biol Chem 2004 Apr 12;279(17):17826-33. Epub 2004 Feb 12.

Henry Wellcome Biogerontology Laboratory, School of Clinical Medical Sciences, University of Newcastle, General Hospital, Newcastle NE4 6BE, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M311980200DOI Listing
April 2004

Dementia rating and nicotinic receptor expression in the prefrontal cortex in schizophrenia.

Biol Psychiatry 2003 Dec;54(11):1222-33

Institute for Ageing and Health, Newcastle General Hospital, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1016/s0006-3223(03)00348-2DOI Listing
December 2003