Carmel M Quinn

Carmel M Quinn

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Carmel M Quinn

Carmel M Quinn

Publications by authors named "Carmel M Quinn"

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HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export.

Circ Res 2015 Mar 14;116(7):1133-42. Epub 2015 Jan 14.

From the Centre for Vascular Research, University of New South Wales, Sydney, New South Wales, Australia (X.-M.D., M.-J.K., L.H., S.P.C., C.M.Q., K.-A.R); INSERM, UMR_1166, Research Institute of Cardiovascular Disease, Metabolism and Nutrition, Pitié-Salpétrière University Hospital, Paris, France (W.L.G., M.J.C., A.K.); Université Pierre et Marie Curie-Paris 6, Paris, France (W.L.G., M.J.C., A.K.); Division of Biopharmaceutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands (M.V.E.); Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA (L.K.C.); Department of Clinical Biochemistry, Royal Perth Hospital, Perth, Western Australia, Australia (J.R.B.); School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia (J.R.B.); Atherosclerosis Laboratory, ANZAC Research Institute, University of Sydney, Sydney, New South Wales, Australia (M.K., L.K., W.J.); and Department of Cardiology, Concord Hospital, Sydney, New South Wales, Australia (L.K.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.305485DOI Listing
March 2015

Sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is a novel nucleotide phosphodiesterase regulated by cholesterol in human macrophages.

J Biol Chem 2014 Nov 6;289(47):32895-913. Epub 2014 Oct 6.

From the Atherosclerosis Laboratory, ANZAC Research Institute, University of Sydney, Sydney, New South Wales 2139, the Department of Cardiology, Concord Repatriation General Hospital, Concord, New South Wales 2139, Australia.

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http://dx.doi.org/10.1074/jbc.M114.612341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239637PMC
November 2014

Dyslipidemic diabetic serum increases lipid accumulation and expression of stearoyl-CoA desaturase in human macrophages.

Lipids 2011 Oct 15;46(10):931-41. Epub 2011 Jun 15.

School of Medicine and Pharmacology, Fremantle and Royal Perth Hospitals, University of Western Australia, Perth, WA, Australia.

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http://dx.doi.org/10.1007/s11745-011-3578-5DOI Listing
October 2011

Modulation of macrophage fatty acid content and composition by exposure to dyslipidemic serum in vitro.

Lipids 2011 Apr 1;46(4):371-80. Epub 2011 Feb 1.

School of Medicine and Pharmacology, Fremantle and Royal Perth Hospitals, University of Western Australia, Perth, WA, Australia.

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http://dx.doi.org/10.1007/s11745-011-3528-2DOI Listing
April 2011

Independent protective roles for macrophage Abcg1 and Apoe in the atherosclerotic lesion development.

Atherosclerosis 2009 Aug 23;205(2):420-6. Epub 2009 Jan 23.

Gorlaeus Leiden/Amsterdam Center for Drug Research, Leiden University, The Netherlands.

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http://dx.doi.org/10.1016/j.atherosclerosis.2009.01.017DOI Listing
August 2009

Functional implications of plasma membrane condensation for T cell activation.

PLoS One 2008 May 28;3(5):e2262. Epub 2008 May 28.

Centre for Vascular Research, University of New South Wales and the Department of Haematology, Prince of Wales Hospital, Sydney, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0002262PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2384009PMC
May 2008

Myriocin slows the progression of established atherosclerotic lesions in apolipoprotein E gene knockout mice.

J Lipid Res 2008 Feb 31;49(2):324-31. Epub 2007 Oct 31.

Prince of Wales Medical Research Institute, Randwick, NSW 2031, Australia.

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http://dx.doi.org/10.1194/jlr.M700261-JLR200DOI Listing
February 2008

The effect of statins on ABCA1 and ABCG1 expression in human macrophages is influenced by cellular cholesterol levels and extent of differentiation.

Atherosclerosis 2008 Jan 26;196(1):180-9. Epub 2007 Apr 26.

School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney 2052, Australia.

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http://dx.doi.org/10.1016/j.atherosclerosis.2007.03.030DOI Listing
January 2008

Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis.

J Biol Chem 2008 Jan 2;283(2):700-7. Epub 2007 Nov 2.

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney 2052, Australia.

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http://dx.doi.org/10.1074/jbc.M706416200DOI Listing
January 2008

Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis.

J Neurochem 2007 Dec 13;103(5):1764-73. Epub 2007 Sep 13.

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/j.1471-4159.2007.04913.xDOI Listing
December 2007

Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol.

Lipids Health Dis 2007 Apr 5;6:10. Epub 2007 Apr 5.

School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1186/1476-511X-6-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1854894PMC
April 2007

SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR.

Biochem J 2006 Dec;400(3):485-91

School of Biotechnology and Biomolecular Sciences, Biosciences Building D26, The University of New South Wales, Sydney, NSW 2052, Australia.

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http://dx.doi.org/10.1042/BJ20060914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698594PMC
December 2006

Glycosphingolipid accumulation inhibits cholesterol efflux via the ABCA1/apolipoprotein A-I pathway: 1-phenyl-2-decanoylamino-3-morpholino-1-propanol is a novel cholesterol efflux accelerator.

J Biol Chem 2005 Jul 11;280(26):24515-23. Epub 2005 May 11.

Centre for Vascular Research, University of New South Wales, Sydney, New South Wales 2052, Australia.

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http://dx.doi.org/10.1074/jbc.M413862200DOI Listing
July 2005

Expression and regulation of sterol 27-hydroxylase (CYP27A1) in human macrophages: a role for RXR and PPARgamma ligands.

Biochem J 2005 Feb;385(Pt 3):823-30

Centre for Vascular Research, School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia.

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http://dx.doi.org/10.1042/BJ20041776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1134759PMC
February 2005

Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux.

Arterioscler Thromb Vasc Biol 2004 Dec 28;24(12):2365-71. Epub 2004 Oct 28.

School of Biotechnology and Biomolecular Sciences, The University of New South Wales and Centre for Vascular Research, Sydney, Australia.

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http://dx.doi.org/10.1161/01.ATV.0000148707.93054.7dDOI Listing
December 2004

Induction of fibroblast apolipoprotein E expression during apoptosis, starvation-induced growth arrest and mitosis.

Biochem J 2004 Mar;378(Pt 3):753-61

Centre for Vascular Research, School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia.

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http://dx.doi.org/10.1042/BJ20031352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224017PMC
March 2004

Apolipoprotein A-1 interaction with plasma membrane lipid rafts controls cholesterol export from macrophages.

FASEB J 2004 Mar 20;18(3):574-6. Epub 2004 Jan 20.

Macrophage Biology Group, Centre for Vascular Research, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.

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http://dx.doi.org/10.1096/fj.03-0486fjeDOI Listing
March 2004

Multiple Ets factors and interferon regulatory factor-4 modulate CD68 expression in a cell type-specific manner.

J Biol Chem 2003 Jun 3;278(24):21909-19. Epub 2003 Apr 3.

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M212150200DOI Listing
June 2003