Publications by authors named "Carlos Vieira"

88 Publications

Biochemical response and metals bioaccumulation in planktonic communities from marine areas impacted by the Fundão mine dam rupture (southeast Brazil).

Sci Total Environ 2021 Oct 2;806(Pt 3):150727. Epub 2021 Oct 2.

Programa de Pós-Graduação em Ciências Fisiológicas, Instituto de Ciências Biológicas, Universidade Federal do Rio Grande (FURG), Av. Itália, s/n, Carreiros, Rio Grande, RS, Brazil; Fundação Espírito-santense de Tecnologia - FEST. Av. Fernando Ferrari, 845 - Goiabeiras, Vitória, ES, Brazil.

The rupture of the Fundão dam (Mariana, MG, southeast Brazil) released a huge flood of mine tailings to Doce river basin and its adjacent coastal area, in November 2015. This catastrophic event exposed aquatic communities to metal contamination related to mine tailings, but its biological effects are still poorly understood. This study investigates how biochemical response related to metal exposure vary between locations and seasons during the years of 2018-2020, in planktonic communities (micro and mesoplankton). Marine microplankton collected in sectors in front and south of the Doce river mouth presented the highest lipid peroxidation (LPO) and induction of metallothioneins (MT). Mesoplankton collected in sectors in front and north of the Doce river mouth presented highest LPO, while MT in this size class did not respond to a clear spatial pattern. Our results showed that metals affected biomarkers in a non-linear pattern and highlighted the complex relationship between metals, biochemical parameters, and seasonality. The variation in biochemical biomarkers indicates physiological stress related to metals, once sectors contaminated by metals, especially Fe, Mn and Cd, presented stronger biochemical responses. Comparison of metal levels with bioaccumulation data collected before the impact indicates Fe, Cd, Cr and Cu more than 2-fold higher after disaster in sectors closer to the river. Literature showed that these sectors present zooplanktonic assemblages with lower biomass and biodiversity, suggesting that the opportunistic species that thrives in the area are also under biochemical stress, but possibly relies on repair or defense mechanisms. The physiological stress detected by this study is possibly related to the mine tailings, considering the metals that stood out and the proximity with the Doce river mouth. This suggests that the impacts related to the failure of Fundão dam are still affecting the marine planktonic community even three to four years after the environmental disaster.
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http://dx.doi.org/10.1016/j.scitotenv.2021.150727DOI Listing
October 2021

The reliability and validity of the 30-seconds sit-to-stand test and its capacity for assessment of the functional status of hemodialysis patients.

J Bodyw Mov Ther 2021 Jul 4;27:157-164. Epub 2021 Mar 4.

Physical Therapy School, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Minas Gerais, Brazil.

Purpose: To investigate the validity of the 30-seconds sit-to-stand test (STS-30) and its reliability in hemodialysis patients.

Methods: Patients receiving hemodialysis treatment three times a week for at least six months were evaluated using STS-30, Incremental Shuttle Walking Test, and health-related quality of life by KDQOL-SF questionnaire. The data obtained from the Incremental Shuttle Walking Test were divided into tertiles, and the STS-30 results were compared among tertiles. The accuracy of the STS-30 to identify low exercise capacity was evaluated. A second STS-30 was performed after 6 to 8-weeks for the reliability analyses using Intraclass Correlation Coefficient (ICC). Minimal detectable change scores were calculated.

Results: Sixty-three individuals (66.7% men) aged 48.3 years (95%CI 44.6-51.9) were evaluated. There were significant correlations between STS-30, exercise capacity (r = 0.72), and physical domains of health-related quality of life (0.30 ≤ r ≤ 0.51). Tertile 1 of the Incremental Shuttle Walking Test was different from tertiles 2 and 3 for STS-30 [difference of 3.4 repetitions (95%CI 1.5-5.4) and 4.7 repetitions (95%CI 2.8-6.7), respectively]. The value of 12 repetitions was the cut-off points for stratification of individuals with low exercise capacity. The STS-30 had a high test-retest reliability (ICC = 0.93) and the minimal detectable change was 2.1 repetitions.

Conclusion: The STS-30 is a reliable test, associated with exercise capacity and physical domains of health-related quality of life. Thus, is a valid method for functional evaluation in hemodialysis patients.
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http://dx.doi.org/10.1016/j.jbmt.2021.02.020DOI Listing
July 2021

Natural Fibers as an Alternative to Synthetic Fibers in Reinforcement of Geopolymer Matrices: A Comparative Review.

Polymers (Basel) 2021 Jul 28;13(15). Epub 2021 Jul 28.

North Caucasus Branch, Belgorod State Technological University Named after V.G. Shukhov, 357202 Mineralnye Vody, Russia.

Geopolymer materials have been gaining ground in the civil construction sector not only for having superior physical properties when compared to conventional cement, but also for being less harmful to the environment, since the synthesis of the geopolymer does not release toxic gases or require high energy costs. On the other hand, geopolymer materials like cementitious matrices have low flexural strength and have fragile breakage. To overcome these deficiencies, the insertion of fibers in geopolymeric matrices has been evaluated as a solution. Although most research on this practice focuses on the use of synthetic fibers, the use of natural fibers has been growing and brings as an advantage the possibility of producing an even more ecological material, satisfying the need to create eco-friendly materials that exists today in society. Thus, this paper aimed to, through the evaluation of research available in the literature, understand the behavior of fibers in geopolymer matrices, identify similarities and differences between the performance of geopolymer composites reinforced with natural and synthetic fibers and, understanding that it is possible, point out ways to optimize the performance of these composites.
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http://dx.doi.org/10.3390/polym13152493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347070PMC
July 2021

Materials for Production of High and Ultra-High Performance Concrete: Review and Perspective of Possible Novel Materials.

Materials (Basel) 2021 Jul 31;14(15). Epub 2021 Jul 31.

LAMAV-Advanced Materials Laboratory, UENF-State University of the Northern Rio de Janeiro, Av. Alberto Lamego, 2000, Campos dos Goytacazes 28013-602, Brazil.

This review article proposes the identification and basic concepts of materials that might be used for the production of high-performance concrete (HPC) and ultra-high-performance concrete (UHPC). Although other reviews have addressed this topic, the present work differs by presenting relevant aspects on possible materials applied in the production of HPC and UHPC. The main innovation of this review article is to identify the perspectives for new materials that can be considered in the production of novel special concretes. After consulting different bibliographic databases, some information related to ordinary Portland cement (OPC), mineral additions, aggregates, and chemical additives used for the production of HPC and UHPC were highlighted. Relevant information on the application of synthetic and natural fibers is also highlighted in association with a cement matrix of HPC and UHPC, forming composites with properties superior to conventional concrete used in civil construction. The article also presents some relevant characteristics for the application of HPC and UHPC produced with alkali-activated cement, an alternative binder to OPC produced through the reaction between two essential components: precursors and activators. Some information about the main types of precursors, subdivided into materials rich in aluminosilicates and rich in calcium, were also highlighted. Finally, suggestions for future work related to the application of HPC and UHPC are highlighted, guiding future research on this topic.
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http://dx.doi.org/10.3390/ma14154304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347951PMC
July 2021

A pilot randomized controlled trial of smartphone-assisted mindfulness-based intervention with contingency management for smokers with mood disorders.

Exp Clin Psychopharmacol 2021 Jul 22. Epub 2021 Jul 22.

School of Nursing.

Cigarette smoking disproportionately affects individuals with mood disorders, but smoking cessation interventions have modest effects in this population. Home mindfulness practice during abstinence incentivized via contingency management (CM) may help those in affective distress quit smoking.

Method: Adult smokers receiving outpatient psychiatric treatment for mood disorders were randomized to receive a smartphone-assisted mindfulness-based smoking cessation intervention with contingency management (SMI-CM, = 25) or enhanced standard treatment (EST, = 24) with noncontingent rewards. Participants in SMI-CM were prompted to practice audio-guided mindfulness five times per day for 38 days (vs. no comparison intervention in EST), and received monetary incentives for carbon monoxide (CO) ≤ 6 ppm. The primary outcome was biochemically verified 7-day point prevalence abstinence rates 2, 4, and 13 weeks after a target quit day.

Results: Of the 49 participants, 63.3% were Latinx and 30.6% Black; 75.5% reported household incomes < $25,000. Abstinence rates for SMI-CM were 40.0%, 36.0%, and 16.0% versus 4.2%, 8.3%, and 4.2% in EST at weeks 2, 4, and 13. A generalized estimating equations (GEE) model showed significant overall differences in abstinence rates in SMI-CM versus EST (adjusted odds ratio [A] = 8.12, 95% CI = 1.42-46.6, = .019). Those who received SMI-CM reported significantly greater reduction in smoking-specific experiential avoidance from baseline to 3 days prior to quit date (β = -7.21, 95% CI = -12.1-2.33, = .006).

Conclusions: SMI-CM may increase cessation rates among smokers with mood disorders, potentially through reduced smoking-specific experiential avoidance. SMI-CM is a promising intervention, and warrants investigation in a fully powered randomized controlled trial (RCT). (PsycInfo Database Record (c) 2021 APA, all rights reserved).
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http://dx.doi.org/10.1037/pha0000506DOI Listing
July 2021

[Active COVID-19 clusters in Santa Catarina, Brazil, and workplace mobility trends].

Cad Saude Publica 2021 25;37(6):e00301620. Epub 2021 Jun 25.

Universidade Federal de Santa Catarina, Florianópolis, Brasil.

The application of spatial analysis to the study of human epidemiological data has gained great momentum in the last two decades. This article approaches the scan statistic for the detection of spatial-temporal clusters of COVID-19 cases in the State of Santa Catarina, Brazil. The aim is to apply the scan statistic to identify active clusters, determining their location, size, and order (priority). Organization of the descriptive based included COVID-19 cases from March 1 to August 31, 2020, available in the Santa Catarina State Open Data Portal. The vector base of the municipal limits and mesoregions in Santa Catarina and the population estimates for 2020 were obtained from the Brazilian Institute of Geography and Statistics (IBGE) website. The workplace mobility trend covariable was obtained from the document COVID-19: Report on Community Mobility in Google. Execution of the statistic considered the discrete Poisson model, supported by the prospective approach. The study's results evidenced the procedure's capacity to demarcate clusters, identifying 17 active clusters with the response variable and 18 active clusters after inclusion of the covariable, distributed throughout the state and predominantly on the coast and the Western region. The primary cluster was in Southern Santa Catarina. The workplace mobility trend covariable moderately influenced 38.89% of the clusters. The method proved to be efficient for understanding the epidemic's spatial distribution. This characterizes the scan statistic as a tool to support the execution of actions by policymakers, prioritizing areas most affected by the disease.
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http://dx.doi.org/10.1590/0102-311X00301620DOI Listing
July 2021

Structural resistance of orthodontic mini-screws inserted for extra-alveolar anchorage.

Acta Odontol Latinoam 2021 Apr;34(1):27-34

Universidade Federal de Uberlândia, Faculdade de Odontologia, Programa de Pós-Graduação em Odontologia, Uberlândia, Brasil.

The risk of fracture or strain in mini-screws is higher if diameter, length, type of alloy or insertion angle is selected inappropriately. The aims of this study were to test the structural resistance of two types of orthodontic mini-screws -one made of stainless steel and another of titanium- from an international brand and to evaluate the efficacy of two other titanium miniscrews of Brazilian origin, during an extra-alveolar anchorage procedure. The mini-screws analyzed were: Bomei stainless steel and Bomei titanium / Taiwan, Morelli titanium and Neodent titanium/ Brazil. Experiments were conducted on pig mandibles to simulate the process of extra-alveolar anchorage. Two insertion processes were used: Direct at 30º, and Indirect, starting at 60º and ending at 30º with gradual continuous movement. Strain was evaluated using Optical and Scanning Electron Microscopy. Data were evaluated using Kruskal-Wallis non-parametric statistical analysis and post hoc Tamhane test. Significant statistical differences in strain were observed among the mini-screws used in the extra-alveolar insertions, both for the direct and indirect procedures. In the indirect insertion tests, both stainless steel and titanium mini-screws suffered deformation, showing that angling can be an important factor in mini-screw failure rates. The change in angle during the insertion movement increased deformation rates independently of alloy type, increasing the risk of failure. These results could help orthodontists in choosing mini-screws for extra-alveolar anchorage, which can be performed with direct or indirect insertion. In vivo studies should be conducted to confirm the findings of this study.
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April 2021

Rheological and the Fresh State Properties of Alkali-Activated Mortars by Blast Furnace Slag.

Materials (Basel) 2021 Apr 20;14(8). Epub 2021 Apr 20.

LAMAV-Advanced Materials Laboratory, UENF-State University of the Northern Rio de Janeiro, Av. Alberto Lamego, 2000, 28013-602 Campos dos Goytacazes, Brazil.

The fresh and rheological properties of alkali mortars activated by blast furnace slag (BFS) were investigated. Consistency tests, squeeze flow, dropping ball, mass density in the hardened state, incorporated air, and water retention were performed. Mortars were produced with the ratio 1:2:0.45 (binder:sand:water), using not only ordinary Portland cement for control but also BFS, varying the sodium content of the activated alkali mortars from 2.5 to 15%. The results obtained permitted understanding that mortars containing 2.5 to 7.5% sodium present a rheological behavior similar to cementitious mortars by the Bingham model. In turn, the activated alkali mortars containing 10 to 15% sodium showed a very significant change in the properties of dynamic viscosity, which is associated with a change in the type of model, starting to behave similar to the Herschel-Bulkley model. Evaluating the properties of incorporated air and water retention, it appears that mortars containing 12.5% and 15% sodium do not have compatible properties, which is related to the occupation of sodium ions in the interstices of the material. Thus, it is concluded that the techniques used were consistent in the rheological characterization of activated alkali mortars.
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http://dx.doi.org/10.3390/ma14082069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073173PMC
April 2021

Surgical treatment of verrucous carcinoma: a review.

J Dermatolog Treat 2021 Apr 14:1-19. Epub 2021 Apr 14.

Cooper Center for Dermatologic Surgery, Evesham, NJ.

Background: Verrucous carcinoma is a rare mucocutaneous malignancy characterized by slow, relentless growth and a low metastasis rate.

Objective: Herein we summarize surgical success rates and review newer approaches to the treatment of verrucous carcinomas. PubMed electronic searches were performed by B.F. and C.V. using combinations of the following terms: ''verrucous carcinoma,'' ''Ackerman tumor,'' ''Buschke Lowenstein,'' ''epithelioma cuniculatum,'' ''carcinoma cuniculatum,'' ''papillomatosis cutis,'' ''treatment,'' ''therapeutics,'' ''management,'' ''mohs surgery,'' and ''excision.'' A systematic review was conducted on 49 articles in accordance with PRISMA guidelines.

Results: Surgical management remains first-line therapy. Wide local excision is most commonly utilized, with highly variable margins (0.5-3.0 cm) and recurrence rates (4.6-75.0%). Mohs Micrographic Surgery has also been used, especially for recurrent tumors, with an overall recurrence rate of 12.9%.

Conclusion: Surgery is the treatment of choice, either by Mohs Micrographic Surgery or wide local excision. However, surgical recurrence rates are high, and tissue-sparing therapies are desirable given the sensitive locations involved. Ultimately, randomized control trials are needed to develop evidence-based guidelines for the management of VCs.
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http://dx.doi.org/10.1080/09546634.2021.1914312DOI Listing
April 2021

Can the insecticide Imidacloprid affect the health of the Neotropical freshwater fish Astyanax altiparanae (Teleostei: Characidae)?

Environ Toxicol Pharmacol 2021 Jul 16;85:103634. Epub 2021 Mar 16.

Natural Resources Institute, Federal University of Itajubá, Av. BPS, Pinheirinho, Itajubá, MG, CEP 37500-903, Brazil. Electronic address:

Female juveniles of the Neotropical fish Astyanax altiparanae were exposed for 96 h to four treatments containing the active ingredient from Imidacloprid® commercial formulation (IMI 1, IMI 2, IMI 3, and IMI 4) and to a control treatment (only dechlorinated tap water). Glutathione content, glutathione S-transferase activity, lipid peroxidation (LPO) and protein carbonylation levels, acetylcholinesterase (AChE) activity, and frequency of micronuclei and erythrocyte nuclear abnormalities (ENA) were measured in the fish. The muscle and gills were the most affected organs; their antioxidant defense was not enough to prevent oxidative damage (LPO) in the IMI 2 and IMI 4 treatment fish. IMI also inhibited AChE activity in the muscle (IMI 3 and IMI 4) and increased ENA frequency (IMI 4). IMI can affect the health of A. altiparanae in environmentally relevant concentrations, causing oxidative damage in different organs, neurotoxic effects in the muscle, and genotoxicity.
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http://dx.doi.org/10.1016/j.etap.2021.103634DOI Listing
July 2021

Effect of both dance exergame and a traditional exercise on state anxiety and enjoyment in women.

J Sports Med Phys Fitness 2021 Mar 15. Epub 2021 Mar 15.

Laboratório de Avaliação do Movimento Humano, Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiânia, Brazil -

Background: Anxiety disorders affect many people around the world and women are more affected than men. Physical exercise might be an important nonpharmacological tool to ameliorate these disorders. The aim of this study was to compare state anxiety level and enjoyment between a dance exergame session and a traditional aerobic exercise.

Methods: Twenty healthy young women completed 3 visits, on separate days. At the first visit, participants performed a graded exercise testing and familiarization procedures. In other two visits, participants completed two exercise sessions (dance exergame and traditional aerobic exercise), with similar intensities and duration. Each session lasted approximately 45 minutes. State anxiety level was evaluated before, immediately post- and 10 minutes post sessions. Enjoyment was evaluated immediately post sessions.

Results: There was a significant interaction between session and time (p<0.001), a main effect of time (p=0.007) but no significant main effect of session (p=0.057) on state anxiety level. State anxiety level immediately post (p<0.001) and 10 minutes post-session (p<0.001) were significantly lower than pre-dance exergame session. There were no significant changes between pre-, immediately post and 10 minutes post-traditional aerobic exercise session (p>0.05). State anxiety level at immediately post dance exergame session was significantly lower than immediately post traditional aerobic exercise session (p=0.026). Dance exergame session was significantly more enjoyable than traditional aerobic exercise session (p<0.0001).

Conclusions: Dance exergames might be used as a tool to reduce anxiety level in young women.
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http://dx.doi.org/10.23736/S0022-4707.21.12237-6DOI Listing
March 2021

Resistance Training, Fatigue, Quality of Life, Anxiety in Breast Cancer Survivors.

J Strength Cond Res 2021 May;35(5):1350-1356

College of Physical Education and Dance, Federal University of Goias, Goiania, GO, Brazil.

Abstract: Moraes, RF, Ferreira-Júnior, JB, Marques, VA, Vieira, A, Lira, CAB, Campos, MH, Freitas-Junior, R, Rahal, RMS, Gentil, P, and Vieira, CA. Resistance training, fatigue, quality of life, anxiety in breast cancer survivors. J Strength Cond Res 35(5): 1350-1356, 2021-Resistance training (RT) has shown to be effective in improving fatigue, quality of life (QOL), and anxiety levels among breast cancer survivors (BCS), but there is no consensus as to how this practice should be prescribed for optimal performance. This study analyses the effects of once weekly RT on fatigue, QOL, and anxiety levels among BCS. Randomized controlled trial. Twenty-five BCS (aged 54.6 ± 5.5 years) were randomized into RT or control groups. The RT group performed 8 weeks of RT (once per week). Fatigue was assessed using the Piper Fatigue scale, QOL was assessed using the SF-36, and anxiety was assessed using the STAI State-Trait Anxiety Inventory. Resistance training significantly improved the following subscales of SF-36: aspects of physical functioning (+27%, p = 0.027); physical role functioning (+54%, p = 0.008); emotional role functioning (+42%, p = 0.027); and mental health (+16%, p = 0.032). Furthermore, RT improved fatigue levels (-55%, p = 0.001 for general fatigue) and anxiety (anxiety state, -19%, p = 0.012; anxiety trait, -23%, p = 0.001). Resistance training seemed to be a positive nonpharmacological tool for the reduction of fatigue, anxiety, and for improvement of several aspects of QOL in BCS.
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http://dx.doi.org/10.1519/JSC.0000000000003817DOI Listing
May 2021

Presence of exercise physiology or similar coursework in the curricula of Brazilian health science undergraduate programs.

Adv Physiol Educ 2021 Mar;45(1):172-177

Programa de Pós-Graduação em Ciências Aplicadas à Saúde, Universidade Federal de Jataí, Jataí, Brazil.

Bolstered by evidence of the health benefits of exercise, health professionals advise their patients about it. Thus these professionals should have a basic knowledge of exercise physiology. In Brazil, a graduate degree is not mandatory, so for many health providers, the only opportunity to receive information on exercise physiology content is during their undergraduate study. Therefore, it is imperative that health science undergraduate programs include content on exercise physiology. The aim of the study was to verify the presence of exercise physiology (or similar coursework) in the curricula of seven health science undergraduate programs (biomedicine, physical education, nursing, physiotherapy, medicine, nutrition, and psychology). The study was divided into three phases: ) a survey of the total number of undergraduate programs ( = 4,940) through an electronic system of the Brazilian Ministry of Education (e-MEC); ) a random selection of 10% of the total undergraduate programs ( = 494) for further analysis of the curriculum; and ) analysis of the curricula of the selected undergraduate programs. Of 494 undergraduate programs, we did not find curricula for 77 of them. Therefore, the final sample consisted of 417 undergraduate programs. In total, 65.9% of the undergraduate programs did not offer coursework in exercise physiology. The chi-square test revealed a significant association between undergraduate curricula in health science and the presence or absence of exercise physiology coursework [(6, = 417) = 293.0, < 0.0001]. We did not find exercise physiology coursework in most of the analyzed undergraduate programs. Alternatives to solve the lack of exercise physiology coursework would be the inclusion of content related to exercise physiology in professional/graduate education or in continuing education programs.
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http://dx.doi.org/10.1152/advan.00044.2020DOI Listing
March 2021

Effects of Chemotherapy Treatment on Muscle Strength, Quality of Life, Fatigue, and Anxiety in Women with Breast Cancer.

Int J Environ Res Public Health 2020 10 6;17(19). Epub 2020 Oct 6.

Postgraduate Program in Health Sciences, Federal University of Goias, Goiania 74605-050, GO, Brazil.

The study aimed to evaluate the effects of chemotherapy treatment on muscle strength, quality of life, fatigue, and anxiety in women with breast cancer. Nineteen women who were undergoing a chemotherapy treatment (breast cancer treatment [BCT] group, 52.2 ± 13.1 years) and 18 women without cancer (control [CNT] group, 55.8 ± 8.4 years) answered questionnaires for evaluation of fatigue (Fatigue Scale), quality of life (Short-Form Healthy Survey [SF-36] questionnaire), and anxiety (State-Trait Anxiety Inventory [IDATE]) levels. Muscle strength was also assessed by an isometric grip test and an isokinetic knee extension test. Physical limitations, social and emotional domains of quality of life were lower in the BCT group in comparison to the CNT group ( = 0.002; = 0.003; = 0.0003, respectively). The other domains did not differ between groups ( > 0.05). There were no differences in fatigue and anxiety levels between both the BCT and CNT groups ( > 0.05). Additionally, isometric grip strength was higher in the CNT group when compared to the BCT group ( = 0.048). However, there were no differences between the BCT and CNT groups for peak torque and total work at both 60°.s ( = 0.95 and = 0.61, respectively) and 180°.s ( = 0.94 and = 0.72, respectively). These results suggest that three cycles of chemotherapy treatment may impair handgrip isometric strength and quality of life in women with breast cancer.
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http://dx.doi.org/10.3390/ijerph17197289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579368PMC
October 2020

Maximal inspiratory pressure is associated with health-related quality of life and is a reliable method for evaluation of patients on hemodialysis.

Physiother Theory Pract 2020 Sep 11:1-9. Epub 2020 Sep 11.

Programa de Pós-Graduação em Reabilitação e Desempenho Funcional, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Brazil.

Objective: To evaluate the association between Maximal Inspiratory Pressure (MIP) and health-related quality of life (HRQoL) and to verify the reliability of the MIP in patients on hemodialysis.

Methods: In a repeated-measures design, patients on hemodialysis performed MIP and specific HRQoL questionnaire (trial 1). The MIP was repeated after 6 to 8 weeks (trial 2) and reliability was assessed using Intra-class Correlation Coefficient. Standard Error of Measurement and Minimal Detectable Change scores were calculated.

Results: Sixty-one individuals (68.9% men) were evaluated in trial 1. MIP was associated with specific domains "Symptoms" (r = 0.45; R adjusted = 0.192) and the kidney disease component summary (r = 0.38; R adjusted = 0.138). Regarding generic domains, the MIP was associated with "Physical Functioning" (r = 0.57; R adjusted = 0.375) and Physical component summary (r = 0.47; R adjusted = 0.258). Thirty-three patients were randomly selected to perform a second MIP test (trial 2). The Intra-class Correlation Coefficient was 0.94 (95%CI 0.88-0.97). By Bland-Altman analysis, the bias was 3.2 cmH2O, which represents a difference of 3.7%. The Standard Error of Measurement and Minimal Detectable Change for MIP were 5.9 cmH2O and 13.8 cmH2O, respectively.

Conclusion: The MIP is a reliable test, associated with physical domains of HRQoL in patients on hemodialysis. Thus, it is a useful method for respiratory evaluation in this population.
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http://dx.doi.org/10.1080/09593985.2020.1818338DOI Listing
September 2020

NEOTROPICAL CARNIVORES: a data set on carnivore distribution in the Neotropics.

Ecology 2020 11;101(11):e03128

Independent researcher, Rua Afonso Pena, 226, Lavras, MG, 37200-000, Brazil.

Mammalian carnivores are considered a key group in maintaining ecological health and can indicate potential ecological integrity in landscapes where they occur. Carnivores also hold high conservation value and their habitat requirements can guide management and conservation plans. The order Carnivora has 84 species from 8 families in the Neotropical region: Canidae; Felidae; Mephitidae; Mustelidae; Otariidae; Phocidae; Procyonidae; and Ursidae. Herein, we include published and unpublished data on native terrestrial Neotropical carnivores (Canidae; Felidae; Mephitidae; Mustelidae; Procyonidae; and Ursidae). NEOTROPICAL CARNIVORES is a publicly available data set that includes 99,605 data entries from 35,511 unique georeferenced coordinates. Detection/non-detection and quantitative data were obtained from 1818 to 2018 by researchers, governmental agencies, non-governmental organizations, and private consultants. Data were collected using several methods including camera trapping, museum collections, roadkill, line transect, and opportunistic records. Literature (peer-reviewed and grey literature) from Portuguese, Spanish and English were incorporated in this compilation. Most of the data set consists of detection data entries (n = 79,343; 79.7%) but also includes non-detection data (n = 20,262; 20.3%). Of those, 43.3% also include count data (n = 43,151). The information available in NEOTROPICAL CARNIVORES will contribute to macroecological, ecological, and conservation questions in multiple spatio-temporal perspectives. As carnivores play key roles in trophic interactions, a better understanding of their distribution and habitat requirements are essential to establish conservation management plans and safeguard the future ecological health of Neotropical ecosystems. Our data paper, combined with other large-scale data sets, has great potential to clarify species distribution and related ecological processes within the Neotropics. There are no copyright restrictions and no restriction for using data from this data paper, as long as the data paper is cited as the source of the information used. We also request that users inform us of how they intend to use the data.
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http://dx.doi.org/10.1002/ecy.3128DOI Listing
November 2020

"NO LOAD" Resistance Training Promotes High Levels of Knee Extensor Muscles Activation-A Pilot Study.

Diagnostics (Basel) 2020 Jul 29;10(8). Epub 2020 Jul 29.

Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiania 74690-900, Brazil.

The present article aims to compare electromyographic (EMG) activity of the knee extensors during traditional resistance training (TRT) and no load resistance training with or without visual feedback (NL-VF and NL-NF). Sixteen healthy men (age: 25.2 ± 3.6) volunteered to participate in the study. Participants visited the laboratory on three occasions involving: (1) a 10 repetition maximum test (10 RM test), (2) familiarization and (3) performance of knee extensions using TRT, NL-VF and NL-NF in a random order, with 10 min of rest between them. TRT involved the performance of a set to momentary muscle failure using the 10 RM load. NL-NF involved the performance of 10 repetitions with no external load, but with the intention to maximally contract the muscles during the whole set. NL-VF involved the same procedure as NL-NF, but a monitor was positioned in front of the participants to provide visual feedback on the EMG activity. Peak and mean EMG activity were evaluated on the vastus medialis (VM), vastus lateralis (VL) and rectus femoris (RF). Results: there were no significant differences in VM and VL peak EMG activity among different situations. There was a significant difference for peak EMG activity for RF, where TRT resulted in higher values than NL-VF and NL-NF ( < 0.05). Higher values of mean EMG activity were found for VM, VL and RF during TRT in comparison with both NL-VF and NL-NF. Conclusions: resistance training with no external load produced high levels of peak muscle activation, independent of visual feedback, but mean activation was higher during TRT. These results suggest that training with no external load might be used as a strategy for stimulating the knee extensors when there is limited access to specialized equipment. Although the clinical applications of no load resistance training are promising, it is important to perform long-term studies to test if these acute results will reflect in muscle morphological and functional changes.
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http://dx.doi.org/10.3390/diagnostics10080526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459905PMC
July 2020

NEOTROPICAL ALIEN MAMMALS: a data set of occurrence and abundance of alien mammals in the Neotropics.

Ecology 2020 11;101(11):e03115

Universidade Federal da Integração Latino-Americana, Foz do Iguaçu, Paraná, Brazil.

Biological invasion is one of the main threats to native biodiversity. For a species to become invasive, it must be voluntarily or involuntarily introduced by humans into a nonnative habitat. Mammals were among first taxa to be introduced worldwide for game, meat, and labor, yet the number of species introduced in the Neotropics remains unknown. In this data set, we make available occurrence and abundance data on mammal species that (1) transposed a geographical barrier and (2) were voluntarily or involuntarily introduced by humans into the Neotropics. Our data set is composed of 73,738 historical and current georeferenced records on alien mammal species of which around 96% correspond to occurrence data on 77 species belonging to eight orders and 26 families. Data cover 26 continental countries in the Neotropics, ranging from Mexico and its frontier regions (southern Florida and coastal-central Florida in the southeast United States) to Argentina, Paraguay, Chile, and Uruguay, and the 13 countries of Caribbean islands. Our data set also includes neotropical species (e.g., Callithrix sp., Myocastor coypus, Nasua nasua) considered alien in particular areas of Neotropics. The most numerous species in terms of records are from Bos sp. (n = 37,782), Sus scrofa (n = 6,730), and Canis familiaris (n = 10,084); 17 species were represented by only one record (e.g., Syncerus caffer, Cervus timorensis, Cervus unicolor, Canis latrans). Primates have the highest number of species in the data set (n = 20 species), partly because of uncertainties regarding taxonomic identification of the genera Callithrix, which includes the species Callithrix aurita, Callithrix flaviceps, Callithrix geoffroyi, Callithrix jacchus, Callithrix kuhlii, Callithrix penicillata, and their hybrids. This unique data set will be a valuable source of information on invasion risk assessments, biodiversity redistribution and conservation-related research. There are no copyright restrictions. Please cite this data paper when using the data in publications. We also request that researchers and teachers inform us on how they are using the data.
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http://dx.doi.org/10.1002/ecy.3115DOI Listing
November 2020

Priapism Associated With Atypical Antipsychotic Medications: A Clinical Report.

Prim Care Companion CNS Disord 2020 07 16;22(4). Epub 2020 Jul 16.

Department of Psychiatry, Hospital Prof. Doutor Fernando da Fonseca, Amadora, Portugal.

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http://dx.doi.org/10.4088/PCC.19l02543DOI Listing
July 2020

Incidence of Surgical Site Infections in Second Intention Healing After Dermatologic Surgery.

Dermatol Surg 2020 12;46(12):1492-1497

Department of Dermatology, Cooper Center for Dermatologic Surgery, Evesham, New Jersey.

Background: There are few studies analyzing the surgical site infection (SSI) rate of second intention wounds after dermatologic surgery, and the results are inconclusive. Yet, the current dogma in dermatologic surgery is that wounds healed by second intention have lower infection rates.

Objective: To determine the rate of SSI and associated pathogenic organisms of second intention wounds compared with sutured wounds after skin cancer extirpation.

Materials And Methods: This was a retrospective cohort study of patients who had either Mohs micrographic surgery or wide local excision (WLE) for skin cancer extirpation between 2012 and 2016. Wounds were stratified by closure type, location, and associated organisms. Infection was diagnosed by a positive wound culture.

Results: The overall infection rate was 3.9%. The infection rate for sutured and second intention wounds was 3.2% and 6.8%, respectively. Second intention wounds were associated with a significantly higher risk of infection compared with sutured wounds (odds ratio = 2.22, 95% confidence interval 1.63-2.99). The lower extremity (LE) had the highest overall infection rate (10.5%). The face had the lowest overall infection rate (2.5%).

Conclusion: Mohs micrographic surgery or WLE performed on the LE or lesions allowed to heal by second intention has an increased risk of SSI.
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http://dx.doi.org/10.1097/DSS.0000000000002409DOI Listing
December 2020

The effects of exergames on anxiety levels: A systematic review and meta-analysis.

Scand J Med Sci Sports 2020 Jul 15;30(7):1100-1116. Epub 2020 Apr 15.

Laboratório de Avaliação do Movimento Humano, Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiânia, Brazil.

There are currently many different approaches to performing exergames and there is still no consensus as to whether exergames are able to reduce anxiety levels, as well as whether exergames provide greater reductions on anxiety levels when added to traditional forms of clinical interventions. Therefore, the aim of the present systematic review and meta-analysis was to access data from studies that evaluated the effects of exergames on anxiety levels in humans. PubMed, Scopus and Cochrane databases were searched up to 22 February 2019. Inclusion criteria were acute and chronic (short-term and long-term interventions) studies which evaluated the effects of exergames in anxiety levels as primary or secondary aim. Of the 1342 studies found, 17 and 10 were included in qualitative analyses and meta-analyses, respectively. The within-group analysis found that exergames (standardized mean difference [SMD]: -0.57 [95% Confidence interval (CI): -0.86 to -0.28], P < .001) and usual care (SMD: -0.21 [95% CI: -0.34 to -0.08], P = .002) resulted in significant improvements on anxiety levels. However, the between-group meta-analysis on the effects of control interventions vs exergames (SMD: 0.02 [95% CI: -0.55 to 0.60], P = .939) found no significant difference between groups in anxiety levels reductions. There was also no significant difference (SMD: -0.04 [95% CI: -0.32 to 0.25], P = .805) between usual care vs exergames plus usual care interventions in anxiety levels reductions. Although exergames demonstrated within-group improvements in anxiety levels across different clinical populations, it was not greater than the effects from non-exercise interventions. Also, given the paucity of studies, small sample sizes, different research designs, and different population investigated, the existing evidence is insufficient to support the advantages of usual care supplemented by exergame intervention over usual care standalone in anxiety levels reduction.
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http://dx.doi.org/10.1111/sms.13654DOI Listing
July 2020

Studies of Classical Ballet Dancers' Equilibrium at Different Levels of Development and Versus Non-Dancers: A Systematic Review.

J Dance Med Sci 2020 Mar;24(1):33-43

Laboratory of Human Movement Assessment, Faculty of Physical education and dance, Universidade Federal de Goiás, Goiás, Brazil.

In classical ballet, the execution of extreme movements on small bases of support causes the dancers constantly to seek balance. The objective of this systematic literature review was to evaluate the effects of classical ballet training on static and dynamic balance in order to emphasize the differences between dancers and non-dancers and between dancers with different levels of experience. Searches for scientific papers were conducted by two independent researchers in the PubMed, Science Direct, and LILACS databases. A secondary search was carried out by "snowballing" references in the selected studies. A modified Downs and Black checklist and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) scale were used to evaluate the methodological quality and evidence strength of the included studies, respectively. From 364 initial studies, nine were found to be eligible (five did analyses in static situations, two in dyna- mic situations, and two in both). With a maximum potential of 10 points, the methodological quality ranged from 6 to 8 on the Downs and Black checklist. It was found that the level of experience in ballet makes for better balance. However, there are indications that classical ballet dancers become more dependent on vision to control balance compared to non-dancers.
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http://dx.doi.org/10.12678/1089-313X.24.1.33DOI Listing
March 2020

"NO LOAD" resistance training increases functional capacity and muscle size in hospitalized female patients: A pilot study.

Eur J Transl Myol 2019 Oct 12;29(4):8492. Epub 2019 Nov 12.

Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiânia, Goiás, Brasil.

The aim of the present study was to compare the effects of resistance training performed with no external load (NLRT) versus resistance training performed with elastic bands (RTEB) on muscle hypertrophy and functional performance in hospitalized patients. Twenty hospitalized females (age, 59.05±3.2 years; height 163.6±2.5 cm; body mass 70.2±3.6 kgs) were randomly assigned to RTEB or NLRT. Both groups trained three times a week for five weeks. RTEB was performed with elastic bands, while NLRT involved maximum voluntary contractions with no external loads. Biceps brachii, triceps brachii and pectoralis muscle thickness (MT) were measured by ultrasound. Functional performance was measured by the 30s elbow flexion test. MT significantly increased in all muscles tested for both groups, with no differences between groups. Changes ranged from 14 to 38%. Functional performance significantly improved by 42.7% for NLRT and 52.1% for RTEB, with no difference between them. The present results suggest that NLRT might be an efficient, feasible and low-cost strategy to promote morphological and functional benefits in the upper limb of hospitalized patients.
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http://dx.doi.org/10.4081/ejtm.2019.8492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926436PMC
October 2019

Interleukin-6, tumor necrosis factor-α, C-reactive protein, and hematological parameters in experimental periodontal disease after β-adrenergic blockade.

J Indian Soc Periodontol 2019 Nov-Dec;23(6):511-516

Neuroimmune Interface of Pain Research, Faculdade São Leopoldo Mandic, Instituto São Leopoldo Mandic, Campinas, SP, Brazil.

Background: Changes in the levels of C-reactive protein (CRP), tumor necrosis factor α (TNF-α), and interleukin 6 (IL-6) observed during periodontal disease were linked with vascular manifestations. Recent studies showed that the beta-blocker propranolol reduces the pathological parameters associated with certain molecules at sites of bone injury. Hence, in this study, we evaluated the activity of propranolol on hematological parameters and systemic concentrations of inflammatory proteins in a model of experimental periodontitis.

Materials And Methods: Periodontal disease was induced in rats. After euthanasia, the number of inflammatory cells in each rat was quantified using histopathological assays. In addition, hematological parameters were quantitated using automated analysers, cytokine levels were determined using an enzyme-linked immunosorbent assay, and CRP levels were determined using a high-sensitivity immunoturbidimetric assay.

Results: Low doses of propranolol suppressed the systemic production of CRP, TNF-α, and IL-6; however, the hematological parameters were not affected.

Conclusions: β-adrenergic activation indirectly contributes to the pattern of systemic inflammatory molecules observed in periodontal disease. These molecules may initiate cardiovascular diseases as a consequence of periodontitis.
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http://dx.doi.org/10.4103/jisp.jisp_77_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906902PMC
December 2019

Reliability and Agreement of the 10-Repetition Maximum Test in Breast Cancer Survivors.

Front Oncol 2019 26;9:918. Epub 2019 Sep 26.

College of Physical Education and Dance, Federal University of Goias - UFG, Goiânia, Brazil.

The aim of this study was to evaluate the reliability and agreement between the test and retest of the 10-repetition maximum (10-RM) test for leg press and bench press in breast cancer survivors (BCS). Thirty-one BCS participated in this study, age 54.87 ± 5.7 years. All performed 10-RM tests and retests for the leg press 45° and the bench press. For reliability analyses, an intraclass coefficient correlation (ICC) and coefficient of variation (CV) were performed. The limits of agreement were calculated using a Bland-Altman plot with 95% CIs. For absolute and relative error of measurement, we used standard error of measurement and minimally detectable change. The result showed a high reliability for the bench press and leg press; ICC of 0.94 and 0.98, respectively. CV was <10% for both exercises. The systematic error were 1.5 kg (10%) and 6.1 (8%) for the bench press and leg press, respectively. The standard errors of measurements were 0.96 kg (6.08%) and 4.11 kg (5.27%) for the bench press and leg press, respectively. The minimally detectable changes were 2.72 kg (17.20%) and 5.62 kg (7.21%) for the bench press and leg press, respectively. In breast cancer survivors, the muscular strength measurement for the 10-RM test showed a high to very high rate of reliability and agreement, with acceptable error of measurement.
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http://dx.doi.org/10.3389/fonc.2019.00918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775190PMC
September 2019

Effects of Static and Dynamic Stretching Performed Before Resistance Training on Muscle Adaptations in Untrained Men.

J Strength Cond Res 2019 Sep 17. Epub 2019 Sep 17.

University of Brasília, Brasília, DF, Brazil.

Ferreira-Júnior, JB, Benine, RPC, Chaves, SFN, Borba, DA, Martins-Costa, HC, Freitas, EDS, Bemben, MG, Vieira, CA, and Bottaro, M. Effects of static and dynamic stretching performed before resistance training on muscle adaptations in untrained men. J Strength Cond Res XX(X): 000-000, 2019-This study evaluated the effects of dynamic and static stretching (SS) performed before resistance training on biceps femoris hypertrophy and knee flexor strength gains in untrained young men. Forty-five untrained young men (age, 21.2 ± 0.5 years; mass, 72.2 ± 5.6 kg; height, 178 ± 1 cm) were randomly assigned to 1 of the 3 groups: (a) 80 seconds of SS (n = 14); (b) 80 seconds of dynamic stretching (DS, n = 13); or (c) control group (CON, n = 18) in which subjects performed no stretching before exercise. Both SS and DS were performed before resistance exercise. Resistance training consisted of 4 sets of 8-12 repetition maximum of seated leg curl exercise 2 days per week for 8 weeks, with a period of at least 48 hours between sessions. Unilateral biceps femoris muscle thickness (MT) and maximal isometric strength (MIS) of the knee flexors were measured 1 week before training and 1 week after the last training session. There were significant increases in MIS (SS = 13.9 ± 10.3 kgf; DS = 10.2 ± 13.1 kgf; CON = 12.7 ± 7.6 kgf; p < 0.05) and MT (SS = 6.0 ± 3.5 mm; DS = 6.7 ± 4.1 mm; CON = 5.7 ± 3.0 mm; p < 0.05) with no significant differences across groups (p > 0.05). Additionally, all groups demonstrated moderate effect sizes for MIS (1.27-1.4), and DS was the only group that had a large effect size for MT increases (DS = 2.18; SS = 1.35; CON = 0.92). In conclusion, 80 seconds of SS and DS did not induce any additional muscular adaptations to resistance training in untrained young men.
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http://dx.doi.org/10.1519/JSC.0000000000003283DOI Listing
September 2019

Postactivation Potentiation Improves Performance in a Resistance Training Session in Trained Men.

J Strength Cond Res 2019 Sep 25. Epub 2019 Sep 25.

Faculty of Physical Education and Dance, Federal University of Goiás, Goiânia, Brazil.

Alves, RR, Viana, RB, Silva, MH, Guimarães, TC, Vieira, CA, Santos, DdAT, and Gentil, PRV. Postactivation potentiation improves performance in a resistance training session in trained men. J Strength Cond Res XX(X): 000-000, 2019-This study aims to analyze the influence of postactivation potentiation (PAP) on performance during a resistance training (RT) session in trained individuals. Fourteen trained men (25.0 ± 3.5 years; 89.9 ± 16.3 kg; 1.77 ± 0:08 m; 28.0 ± 4.0 kg·m; and 5 ± 4 years of RT experience) were tested in 2 situations: with PAP and without PAP (CON). Both situations involved 3 sets of the bench press exercise performed to muscle failure at 75% of the 1 repetition maximum load and with 1.5-minute interval between sets. Total work was greater (p < 0.001) for PAP (1,601 ± 504 kg) than for CON (1,379 ± 364 kg). The number of repetitions performed in the first and second sets of PAP (11.5 ± 3.1 and 6.5 ± 1.9, respectively) were greater (p < 0.05) than those performed in CON (10.4 ± 2.7, 5.5 ± 1.8, respectively). No significant difference was found in the number of repetitions in the last set between the situations. The present study suggests that PAP might be beneficial to improve total work and performance during multiple sets of RT in trained men. Therefore, PAP might be used during RT to promote higher total work and potentially increase results over long term. Thus, the protocol can use in sports centers, fitness centers, and gyms per coaches and athletes to increase performance and total work in trained individuals.
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http://dx.doi.org/10.1519/JSC.0000000000003367DOI Listing
September 2019

Once a Week Resistance Training Improves Muscular Strength in Breast Cancer Survivors: A Randomized Controlled Trial.

Integr Cancer Ther 2019 Jan-Dec;18:1534735419879748

Federal University of Goias-UFG, Goiania, Brazil.

Exercise has been shown to reduce adverse outcomes related to breast cancer. However, the rate of adherence to physical exercise is very low among breast cancer survivors (BCS). This study investigated the effects of high supervision ratio resistance training (RT), once a week for 8 weeks, on changes in body composition and muscular strength in BCS. Twenty-five female BCS undergoing hormone therapy were randomized into resistance training group (TG, n = 12) or control (CG, n = 13) group. The TG performed 8 weeks of supervised RT, with 1 trainer per volunteer, once a week. Body composition was evaluated by dual-energy X-ray absorptiometry, and muscle strength was evaluated by 10 repetition maximum (10 RM) for leg press (45°) and bench press exercises. A 1-way analysis of variance was used to compare within-group effects at pre- and post-intervention. An analysis of covariance test was used to compare post-intervention values, using pre-intervention measures as covariates. The effect size (ES) was calculated by Cohen's . The TG improved muscle strength in 10 RM leg press (45°; Δ 33.75 ± 11.51 kg, = .02; ES = 0.96) and bench press (Δ 4.08 ± 1.83 kg, = .01; ES = 1.15). Adherence to training was more than 99%. Changes in body composition were not detected. There were no changes in the CG for any assessment. Once-weekly supervised RT could be an alternative to increase the adherence to exercise and improve muscular strength in BCS.
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http://dx.doi.org/10.1177/1534735419879748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767726PMC
March 2020

Assessment of functional performance in Chagas heart disease by Human Activity Profile questionnaire.

Disabil Rehabil 2021 05 17;43(9):1255-1259. Epub 2019 Aug 17.

Departamento de Fisioterapia, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Brazil.

Purpose: To verify the association between Human Activity Profile and functional capacity, functional class and systolic function of the patients with Chagas heart disease (CHD).

Methods: Sixty-two patients with CHD were evaluated by echocardiography, maximal exercise testing and Human Activity Profile questionnaire. The sample was stratified, according to the values of peak oxygen uptake (low or normal), functional class (symptomatic or asymptomatic), and left ventricular ejection fraction (preserved or systolic dysfunction). Linear regression and two-group comparisons analyses were used. Receiver-operating characteristic analysis was used to determine different cutoff values of the Human Activity Profile for low peak oxygen uptake prediction.

Results: Peak oxygen uptake was an independent predictor of Human Activity Profile (-adjusted = 0.27). Patients with low peak oxygen uptake had lower scores in Human Activity Profile [difference of 6.9 (95%CI 2.5-11.4)] than those with normal peak oxygen uptake. Symptomatic patients also showed lower scores when compared to the asymptomatic [difference of 6.2 (95%CI 1.7-10.8)]. There was no difference between left ventricular ejection fraction classes. The Human Activity Profile score of 76.5 was the optimal cut point value in predicting low peak oxygen uptake (sensitivity = 66.0% and specificity = 71.8%).

Conclusion: The Human Activity Profile questionnaire is associated with functional capacity of patients with CHD and is able to identify individuals with low peak oxygen uptake.Implications for rehabilitationFunctional impairment is one of the most common clinical findings in all stages and is an important predictor of poor prognosis of the Chagas heart disease;A patient-derived measure of functional capacity is potentially useful in the setting of the Chagas heart disease;The Human Activity Profile questionnaire is effective in the identification of patients with Chagas heart disease with functional impairment and may be a valid method for functional evaluation.
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http://dx.doi.org/10.1080/09638288.2019.1653999DOI Listing
May 2021

An integrated approach in subtropical agro-ecosystems: Active biomonitoring, environmental contaminants, bioaccumulation, and multiple biomarkers in fish.

Sci Total Environ 2019 May 18;666:508-524. Epub 2019 Feb 18.

Departamento de Ciências Fisiológicas, Universidade Estadual de Londrina, Rod. Celso Garcia Cid, km 380, Londrina, Paraná, Brazil.

Aquatic contamination in agricultural areas is a global problem, characterized by a complex mixture of organic and inorganic pollutants whose effects on biota are unpredictable and poorly investigated. In this context, in the present study, the Neotropical fish Prochilodus lineatus was confined in situ for 120 days in two sites with different levels of anthropic impact: 1) a fish hatchery station, within the State University of Londrina (reference site - REF) and 2) an agro-ecosystem area in one of the most productive regions of southern Brazil (experimental site - EXP). We evaluated multiple biomarkers at different levels of biological organization, such as biotransformation and antioxidant enzymes, oxidative damages, DNA damages and liver histopathology. We also evaluated the occurrence of 22 organochlorine pesticides (OCPs) and 6 trace metals in water and sediment; and 33 current-use pesticides (CUPs) in the water; besides the presence of OCPs in the liver and metals in different tissues of the confined fish. The chemical analysis confirmed that the two environments presented different levels of contamination. We verified a distribution gradient of data in the principal component analysis (PCA), separating the REF fish to one side and the fish at the agricultural area (EXP) to the other side. In general, the biomarker responses were more altered in fish from the EXP than fish from the hatchery station; and this fish presented a greater accumulation of endosulfan (an increase of 18× compared to basal value) and showed oxidative, genetic, and histological damage. Through the Biomarkers Response Index (BRI), we found that the EXP fish demonstrated a decrease in health status compared with the REF fish during the confinement time, due to their exposure to a higher concentration of contaminants. In conclusion, the use of multiple biomarkers at different response levels is an important tool for environmental monitoring.
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http://dx.doi.org/10.1016/j.scitotenv.2019.02.209DOI Listing
May 2019
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