Dr Carlos Palma-Flores, PhD - Instituto Politecnico Nacional   - Catedras-Conacyt Researcher

Dr Carlos Palma-Flores

PhD

Instituto Politecnico Nacional

Catedras-Conacyt Researcher

México, Distrito Federal. | Mexico

Main Specialties: Biochemical Genetics, Biology

Additional Specialties: Molecular and Cell Biology

ORCID logohttps://orcid.org/0000-0002-7150-7314

Dr Carlos Palma-Flores, PhD - Instituto Politecnico Nacional   - Catedras-Conacyt Researcher

Dr Carlos Palma-Flores

PhD

Introduction

Primary Affiliation: Instituto Politecnico Nacional - México, Distrito Federal. , Mexico

Specialties:

Additional Specialties:

Research Interests:

Education

Aug 2015 - Jul 2016
Universidad Autónoma de la Ciudad de México
Postdoctoral Researcher
Oncogenomic and Cancer Proteomics
Jul 2008 - Sep 2014
Universidad Nacional Autónoma de México
PhD in Molecular and Cell Biology
Institute of Biomedical Sciences, UNAM

Experience

Oct 2016
Instituto Politécnico Nacional
CONACYT Catedratic Researcher
Functional Genomics

Publications

12Publications

203Reads

23Profile Views

16PubMed Central Citations

Up-Regulates MicroRNA-643 to Promote Apoptosis by Targeting XIAP in Human Epithelial Colon Cells.

Front Cell Infect Microbiol 2018 8;8:437. Epub 2019 Jan 8.

Programa en Biomedicina Molecular y Red de Biotecnología, Escuela Nacional de Medicina y Homeopatía, Instituto Politécnico Nacional, Mexico City, Mexico.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fcimb.2018.00437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333105PMC
September 2019
11 Reads
2.620 Impact Factor

Chromatin Immunoprecipitation in Early Mouse Embryos.

Methods Mol Biol 2018 ;1752:145-155

Unidad de Investigación Médica en Genética Humana, Hospital de Pediatría, Colonia Doctores, Ciudad de México, Mexico.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-7714-7_14DOI Listing
January 2019
3 Reads

MicroRNAs driving invasion and metastasis in ovarian cancer: Opportunities for translational medicine (Review).

Int J Oncol 2017 May 4;50(5):1461-1476. Epub 2017 Apr 4.

Autonomous University of Mexico City, Genomics Sciences Program, Mexico City, Mexico.

Epithelial ovarian cancer is the fifth most frequent cause of cancer death in women. In spite of the advantages in early detection and treatment options, overall survival rates have improved only slightly in the last decades. Therefore, alternative therapeutic approaches need to overcome resistance and improve the patient survival and outcome. MicroRNAs are evolutionary conserved small non-coding RNAs that function as negative regulators of gene expression by inhibiting translation or inducing degradation of messenger RNAs. In cancer, microRNAs are aberrantly expressed thus representing potential prognostic biomarkers and novel therapeutic targets. The knowledge of novel and unexpected functions of microRNAs is rapidly evolving and the advance in the elucidation of potential clinical applications deserves attention. Recently, a specific set of microRNAs dubbed as metastamiRs have been shown to initiate invasion and metastasis in diverse types of cancer. We reviewed the current status of microRNAs in development and progression of ovarian cancer with a special emphasis on tumor cells invasion and metastasis. Also, we show an update of microRNA functions in oncogenic pathways and discuss the current scenario for potential applications in clinical and translational research in ovarian cancer.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/ijo.2017.3948DOI Listing
May 2017
12 Reads
3.025 Impact Factor

(-)-Epicatechin induces physiological cardiac growth by activation of the PI3K/Akt pathway in mice.

Mol Nutr Food Res 2017 02 10;61(2). Epub 2016 Oct 10.

Subdirección de Enseñanza e Investigación, División de Investigación Biomédica, Centro Médico Nacional 20 de Noviembre, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, San Lorenzo 502, México City, México.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mnfr.201600343DOI Listing
February 2017
8 Reads
4 Citations
4.603 Impact Factor

Association of the rs1801133 variant in the MTHFR gene and sporadic Parkinson's disease.

Folia Neuropathol 2015 ;53(1):24-8

Luz Berenice López Hernández, PhD, Subdirección de Enseñanza e Investigación, Centro Médico Nacional 20 de Noviembre, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, San Lorenzo 502, C.P. 03100, México, D.F., México, phone: 01 52 55 52 00 50 03, fax: 01 52 33 36 32 62 00, e-mail:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/fn.2015.49971DOI Listing
February 2016
6 Reads

Functional Polymorphism rs13306560 of the MTHFR Gene Is Associated With Essential Hypertension in a Mexican-Mestizo Population.

Circ Cardiovasc Genet 2015 Aug 28;8(4):603-9. Epub 2015 May 28.

From the División de Medicina Genómica (J.C.P.-R.), División de Investigación Biomédica (L.J.C.-M., B.R.-R., C.P.-F., B.L.-H.), and Subdirección de Enseñanza e Investigación (R.M.C.-V.), CMN 20 de Noviembre-ISSSTE, México, D.F., México; Departamento de Fisiología y Grupo de Estudio en Genómica y Proteómica de Enfermedades Cardiovasculares, Instituto Nacional de Cardiología "Ignacio Chávez", México, D.F., México (G.V.A., N.M.-R.); Unidad de Genómica de Poblaciones Aplicada a la Salud, Facultad de Química-UNAM, Instituto Nacional de Medicina Genómica, México, D.F., México (S.C.-Q.); Unidad de Investigación en Obesidad, Facultad de Medicina-UNAM, Clínica de Obesidad, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, D.F., México (P.C.); Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, México, D.F., México (R.E.-M., R.M.C.-V.); and Unidad de Medicina Física y Rehabilitación Centro, UMAE, Hospital de Traumatología y Ortopedia "Lomas Verdes", Instituto Mexicano del Seguro Social, México, D.F., México (D.R.-M.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCGENETICS.114.000942DOI Listing
August 2015
40 Reads
5.340 Impact Factor

Reduction of no-reflow and reperfusion injury with the synthetic 17β-aminoestrogen compound Prolame is associated with PI3K/Akt/eNOS signaling cascade.

Basic Res Cardiol 2015 Mar 15;110(2). Epub 2015 Jan 15.

Departamento de Biomedicina Cardiovascular, Instituto Nacional de Cardiología, I. Ch., Juan Badiano No. 1. Colonia Sección XVI, Mexico, DF, 14080, Mexico.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00395-015-0464-yDOI Listing
March 2015
12 Reads
4 Citations
5.414 Impact Factor

(-)-Epicatechin improves mitochondrial-related protein levels and ameliorates oxidative stress in dystrophic δ-sarcoglycan null mouse striated muscle.

FEBS J 2014 Dec 30;281(24):5567-80. Epub 2014 Oct 30.

Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, México, D.F., México; School of Medicine, University of California, San Diego, La Jolla, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/febs.13098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262719PMC
December 2014
8 Reads
2 Citations
4.001 Impact Factor

Description of a utrophin associated protein complex in lipid raft domains of human artery smooth muscle cells.

Biochim Biophys Acta 2014 Mar 20;1838(3):1047-54. Epub 2013 Sep 20.

Sección de Posgrado, Escuela Superior de Medicina, Instituto Politécnico Nacional, México, D.F., Mexico; Subdirección de Enseñanza e Investigación, Centro Médico Nacional 20 de Noviembre, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, México, D.F., Mexico. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamem.2013.09.010DOI Listing
March 2014
46 Reads
1 Citation

Caveolae and non-caveolae lipid raft microdomains of human umbilical vein endothelial cells contain utrophin-associated protein complexes.

Biochimie 2012 Sep 16;94(9):1884-90. Epub 2012 May 16.

Sección de Posgrado, Escuela Superior de Medicina, Instituto Politécnico Nacional, México, D.F., Mexico.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biochi.2012.05.001DOI Listing
September 2012
19 Reads
3 Citations
2.963 Impact Factor