Publications by authors named "Carlos J Ciudad"

64Publications

Detection of a G-Quadruplex as a Regulatory Element in for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins.

Int J Mol Sci 2020 Jul 16;21(14). Epub 2020 Jul 16.

Department of Biochemistry and Physiology, School of Pharmacy and Food sciences, and IN2UB, University of Barcelona, 08028 Barcelona, Spain.

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http://dx.doi.org/10.3390/ijms21145028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404261PMC
July 2020

Targeting replication stress response using polypurine reverse hoogsteen hairpins directed against WEE1 and CHK1 genes in human cancer cells.

Biochem Pharmacol 2020 05 13;175:113911. Epub 2020 Mar 13.

Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences and Institute of Nanoscience and Nanotechnology (IN2UB), University of Barcelona (UB), 08028 Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2020.113911DOI Listing
May 2020

Correction of the aprt Gene Using Repair-Polypurine Reverse Hoogsteen Hairpins in Mammalian Cells.

Mol Ther Nucleic Acids 2020 Mar 24;19:683-695. Epub 2019 Dec 24.

Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain; Institute for Nanoscience and Nanotechnology IN2UB, University of Barcelona, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.omtn.2019.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965513PMC
March 2020

g-Nomic: a new pharmacogenetics interpretation software.

Pharmgenomics Pers Med 2019 29;12:75-85. Epub 2019 May 29.

Department of Information Technology, EUGENOMIC, Barcelona 08012, Spain.

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http://dx.doi.org/10.2147/PGPM.S203585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554524PMC
May 2019

A novel DNA-binding motif in prostate tumor overexpressed-1 (PTOV1) required for the expression of ALDH1A1 and CCNG2 in cancer cells.

Cancer Lett 2019 06 25;452:158-167. Epub 2019 Mar 25.

Biochemistry Service, Vall d'Hebron University Hospital and Universitat Autònoma de Barcelona, Pg. Vall d'Hebron 119-129, Barcelona, 08035, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2019.03.019DOI Listing
June 2019

Parallel Clamps and Polypurine Hairpins (PPRH) for Gene Silencing and Triplex-Affinity Capture: Design, Synthesis, and Use.

Curr Protoc Nucleic Acid Chem 2019 06 26;77(1):e78. Epub 2019 Mar 26.

School of Pharmacy and IN2UB, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/cpnc.78DOI Listing
June 2019

Silencing PD-1 and PD-L1: the potential of PolyPurine Reverse Hoogsteen hairpins for the elimination of tumor cells.

Immunotherapy 2019 04;11(5):369-372

Department of Biochemistry & Physiology School of Pharmacy & Food Sciences & Institute of Nanoscience & Nanotechnology IN2UB University of Barcelona 08028 Barcelona, Spain.

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http://dx.doi.org/10.2217/imt-2018-0215DOI Listing
April 2019

Cancer immunotherapy using PolyPurine Reverse Hoogsteen hairpins targeting the PD-1/PD-L1 pathway in human tumor cells.

PLoS One 2018 6;13(11):e0206818. Epub 2018 Nov 6.

Department of Biochemistry and Physiology, School of Pharmacy, and Institute of Nanoscience and Nanotechnology, University of Barcelona, Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206818PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219785PMC
April 2019

Functional pharmacogenomics and toxicity of PolyPurine Reverse Hoogsteen hairpins directed against survivin in human cells.

Biochem Pharmacol 2018 09 22;155:8-20. Epub 2018 Jun 22.

Department of Biochemistry and Physiology, School of Pharmacy, and IN2UB, University of Barcelona, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bcp.2018.06.020DOI Listing
September 2018

Glucose-6-phosphate dehydrogenase and transketolase modulate breast cancer cell metabolic reprogramming and correlate with poor patient outcome.

Oncotarget 2017 Dec 7;8(63):106693-106706. Epub 2017 Oct 7.

Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.18632/oncotarget.21601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739767PMC
December 2017

Polypurine Reverse Hoogsteen Hairpins as a Gene Silencing Tool for Cancer.

Curr Med Chem 2017 ;24(26):2809-2826

Department of Biochemistry and Physiology, Faculty of Pharmacy, University of Barcelona, Barcelona. Spain.

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http://dx.doi.org/10.2174/0929867324666170301114127DOI Listing
September 2017

Polypurine reverse-Hoogsteen (PPRH) oligonucleotides can form triplexes with their target sequences even under conditions where they fold into G-quadruplexes.

Sci Rep 2017 01 9;7:39898. Epub 2017 Jan 9.

Structure et Instability of Genomes, Sorbonne Universités, Muséum National d'Histoire Naturelle, Inserm U 1154, CNRS UMR 7196, Paris, France.

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http://dx.doi.org/10.1038/srep39898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220335PMC
January 2017

Silencing of CD47 and SIRPα by Polypurine reverse Hoogsteen hairpins to promote MCF-7 breast cancer cells death by PMA-differentiated THP-1 cells.

BMC Immunol 2016 Sep 26;17(1):32. Epub 2016 Sep 26.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, IN2UB, Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037635PMC
http://dx.doi.org/10.1186/s12865-016-0170-zDOI Listing
September 2016

Correction of point mutations at the endogenous locus of the dihydrofolate reductase gene using repair-PolyPurine Reverse Hoogsteen hairpins in mammalian cells.

Biochem Pharmacol 2016 06 7;110-111:16-24. Epub 2016 Apr 7.

Department of Biochemistry and Molecular Biology, School of Pharmacy, IN2UB, University of Barcelona, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bcp.2016.04.002DOI Listing
June 2016

Health benefits of walnut polyphenols: An exploration beyond their lipid profile.

Crit Rev Food Sci Nutr 2017 Nov;57(16):3373-3383

a Department of Nutrition, Food Science and Gastronomy , Facultad de Farmacia y Ciencias de la Alimentación, Universidad de Barcelona , Barcelona , Spain.

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http://dx.doi.org/10.1080/10408398.2015.1126218DOI Listing
November 2017

Alcohol enhances the psychostimulant and conditioning effects of mephedrone in adolescent mice; postulation of unique roles of D3 receptors and BDNF in place preference acquisition.

Br J Pharmacol 2015 Oct 9;172(20):4970-84. Epub 2015 Oct 9.

Department of Pharmacology and Therapeutic Chemistry (Pharmacology Section), Institute of Biomedicine (IBUB), Faculty of Pharmacy, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/bph.13266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621996PMC
October 2015

Effect of Polypurine Reverse Hoogsteen Hairpins on Relevant Cancer Target Genes in Different Human Cell Lines.

Nucleic Acid Ther 2015 Aug 4;25(4):198-208. Epub 2015 Jun 4.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona , Barcelona, Spain .

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http://dx.doi.org/10.1089/nat.2015.0531DOI Listing
August 2015

Urolithin A causes p21 up-regulation in prostate cancer cells.

Eur J Nutr 2016 Apr 12;55(3):1099-112. Epub 2015 May 12.

Biochemistry and Molecular Biology Department, School of Pharmacy, University of Barcelona, Av. Joan XXIII s/n, 08028, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00394-015-0924-zDOI Listing
April 2016

Improved design of PPRHs for gene silencing.

Mol Pharm 2015 Mar 23;12(3):867-77. Epub 2015 Jan 23.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona , 08028 Barcelona, Spain.

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http://dx.doi.org/10.1021/mp5007008DOI Listing
March 2015

Repair of single-point mutations by polypurine reverse Hoogsteen hairpins.

Hum Gene Ther Methods 2014 Oct 14;25(5):288-302. Epub 2014 Oct 14.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona , E08028 Barcelona, Spain .

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http://dx.doi.org/10.1089/hgtb.2014.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208591PMC
October 2014

Walnut polyphenol metabolites, urolithins A and B, inhibit the expression of the prostate-specific antigen and the androgen receptor in prostate cancer cells.

Food Funct 2014 Nov;5(11):2922-30

Nutrition and Food Science Department, School of Pharmacy, University of Barcelona, Barcelona, Spain.

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http://xlink.rsc.org/?DOI=C4FO00542B
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http://dx.doi.org/10.1039/c4fo00542bDOI Listing
November 2014

Stability and immunogenicity properties of the gene-silencing polypurine reverse Hoogsteen hairpins.

Mol Pharm 2014 Jan 27;11(1):254-64. Epub 2013 Nov 27.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona , Av. Diagonal 643, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1021/mp400431fDOI Listing
January 2014

Validation of miRNA-mRNA interactions by electrophoretic mobility shift assays.

BMC Res Notes 2013 Nov 12;6:454. Epub 2013 Nov 12.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Avenue Diagonal 643, Barcelona E-08028, Spain.

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http://dx.doi.org/10.1186/1756-0500-6-454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830445PMC
November 2013

Polypurine reverse Hoogsteen hairpins as a gene therapy tool against survivin in human prostate cancer PC3 cells in vitro and in vivo.

Biochem Pharmacol 2013 Dec 23;86(11):1541-54. Epub 2013 Sep 23.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, 08028 Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2013.09.013DOI Listing
December 2013

The redox state of cytochrome c modulates resistance to methotrexate in human MCF7 breast cancer cells.

PLoS One 2013 13;8(5):e63276. Epub 2013 May 13.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063276PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652835PMC
December 2013

Cocoa flavanol metabolites activate HNF-3β, Sp1, and NFY-mediated transcription of apolipoprotein AI in human cells.

Mol Nutr Food Res 2013 Jun 7;57(6):986-95. Epub 2013 Jan 7.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/mnfr.201200507DOI Listing
June 2013

Identification of novel Sp1 targets involved in proliferation and cancer by functional genomics.

Biochem Pharmacol 2012 Dec 25;84(12):1581-91. Epub 2012 Sep 25.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bcp.2012.09.014DOI Listing
December 2012

Coffee polyphenols change the expression of STAT5B and ATF-2 modifying cyclin D1 levels in cancer cells.

Oxid Med Cell Longev 2012 7;2012:390385. Epub 2012 Aug 7.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1155/2012/390385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424007PMC
November 2012

Underexpression of miR-224 in methotrexate resistant human colon cancer cells.

Biochem Pharmacol 2011 Dec 16;82(11):1572-82. Epub 2011 Aug 16.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bcp.2011.08.009DOI Listing
December 2011

CYP1A1 is overexpressed upon incubation of breast cancer cells with a polyphenolic cocoa extract.

Eur J Nutr 2012 Jun 6;51(4):465-76. Epub 2011 Aug 6.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00394-011-0231-2DOI Listing
June 2012

A lyophilized red grape pomace containing proanthocyanidin-rich dietary fiber induces genetic and metabolic alterations in colon mucosa of female C57BL/6J mice.

J Nutr 2011 Sep 20;141(9):1597-604. Epub 2011 Jul 20.

Department of Biochemistry and Molecular Biology, Biology Faculty, Universitat de Barcelona, Biomedicine Institute from Universitat de Barcelona, and Associated Unit with CSIC (Consejo Superior de Investigaciones Científicas), Barcelona, Spain.

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http://jn.nutrition.org/content/early/2011/07/20/jn.110.1331
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http://jn.nutrition.org/cgi/doi/10.3945/jn.110.133199
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http://dx.doi.org/10.3945/jn.110.133199DOI Listing
September 2011

Coding polypurine hairpins cause target-induced cell death in breast cancer cells.

Hum Gene Ther 2011 Apr 16;22(4):451-63. Epub 2011 Feb 16.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1089/hum.2010.102DOI Listing
April 2011

UDP-glucuronosyltransferase 1A6 overexpression in breast cancer cells resistant to methotrexate.

Biochem Pharmacol 2011 Jan 18;81(1):60-70. Epub 2010 Sep 18.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Av. Diagonal 643, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bcp.2010.09.008DOI Listing
January 2011

Overexpression of S100A4 in human cancer cell lines resistant to methotrexate.

BMC Cancer 2010 Jun 1;10:250. Epub 2010 Jun 1.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1186/1471-2407-10-250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903526PMC
June 2010

Networking of differentially expressed genes in human cancer cells resistant to methotrexate.

Genome Med 2009 Sep 4;1(9):83. Epub 2009 Sep 4.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Diagonal Avenue, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1186/gm83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768990PMC
September 2009

Polypurine hairpins directed against the template strand of DNA knock down the expression of mammalian genes.

J Biol Chem 2009 Apr 3;284(17):11579-89. Epub 2009 Mar 3.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Av. Diagonal 643, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1074/jbc.M900981200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670163PMC
April 2009

Regulation of Sp1 by cell cycle related proteins.

Cell Cycle 2008 Sep 24;7(18):2856-67. Epub 2008 Sep 24.

Department of Biochemistry and Molecular Biology, School of Pharmacy, IBUB, University of Barcelona, Barcelona, Spain.

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http://www.tandfonline.com/doi/abs/10.4161/cc.7.18.6671
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810142PMC
http://dx.doi.org/10.4161/cc.7.18.6671DOI Listing
September 2008

Role of caveolin 1, E-cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells.

BMC Med Genomics 2008 Aug 11;1:35. Epub 2008 Aug 11.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1186/1755-8794-1-35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527490PMC
August 2008

Transcriptional regulation of the 5'-flanking region of the human transcription factor Sp3 gene by NF-1, c-Myb, B-Myb, AP-1 and E2F.

Biochim Biophys Acta 2008 May 10;1779(5):318-29. Epub 2008 Mar 10.

Department of Biochemistry and Molecular Biology, School of Pharmacy, IBUB, University of Barcelona, Av. Diagonal 643, E-08028, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbagrm.2008.02.006DOI Listing
May 2008

Transcriptional regulation of aldo-keto reductase 1C1 in HT29 human colon cancer cells resistant to methotrexate: role in the cell cycle and apoptosis.

Biochem Pharmacol 2008 Jan 8;75(2):414-26. Epub 2007 Sep 8.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Av. Diagonal 643, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bcp.2007.08.034DOI Listing
January 2008

Short-term oleoyl-estrone treatment affects capacity to manage lipids in rat adipose tissue.

BMC Genomics 2007 Aug 28;8:292. Epub 2007 Aug 28.

Departament de Nutrició i Bromatologia, Facultat de Biologia, Universitat de Barcelona, Av, Diagonal 645, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1186/1471-2164-8-292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2020488PMC
August 2007

Pentose phosphate cycle oxidative and nonoxidative balance: A new vulnerable target for overcoming drug resistance in cancer.

Int J Cancer 2006 Dec;119(12):2733-41

Department of Biochemistry and Molecular Biology, Faculty of Biology, CeRQT-Parc Cientific de Barcelona, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/ijc.22227DOI Listing
December 2006

Strand displacement of double-stranded DNA by triplex-forming antiparallel purine-hairpins.

Oligonucleotides 2005 Dec;15(4):269-83

Department of Biochemistry, School of Pharmacy, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1089/oli.2005.15.269DOI Listing
December 2005

Gene identification by cDNA arrays in HPV-positive cervical cancer.

Arch Med Res 2005 Sep-Oct;36(5):448-58

Oncogenomics Laboratory, Oncological Diseases Research Unit, Oncology Hospital, 21st Century National Medical Center, Mexico City, Mexico.

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http://dx.doi.org/10.1016/j.arcmed.2005.04.016DOI Listing
October 2005

Characterization of the 5'-flanking region of the human transcription factor Sp3 gene.

Biochim Biophys Acta 2005 Aug;1730(2):126-36

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Avenue Diagonal 643, Barcelona E-08028, Spain.

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http://dx.doi.org/10.1016/j.bbaexp.2005.06.002DOI Listing
August 2005

Modulation of IMPDH2, survivin, topoisomerase I and vimentin increases sensitivity to methotrexate in HT29 human colon cancer cells.

FEBS J 2005 Feb;272(3):696-710

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.1111/j.1742-4658.2004.04504.xDOI Listing
February 2005

Targeting of sterically stabilised pH-sensitive liposomes to human T-leukaemia cells.

Eur J Pharm Biopharm 2005 Feb;59(2):359-66

Laboratory of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.ejpb.2004.08.012DOI Listing
February 2005

Sensitization of human erythroleukemia K562 cells resistant to methotrexate by inhibiting IMPDH.

Med Sci Monit 2005 Jan;11(1):BR6-12

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Barcelona, Spain.

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January 2005

A highly efficient electroporation method for the transfection of endothelial cells.

Angiogenesis 2004 ;7(3):235-41

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.1007/s10456-004-4180-8DOI Listing
April 2005

Up-regulation of the Kv3.4 potassium channel subunit in early stages of Alzheimer's disease.

J Neurochem 2004 Nov;91(3):547-57

Department of Biochemistry and Molecular Biology, School of Chemistry, Universitat de Barcelona, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1111/j.1471-4159.2004.02771.xDOI Listing
November 2004

Epicatechin and a cocoa polyphenolic extract modulate gene expression in human Caco-2 cells.

J Nutr 2004 Oct;134(10):2509-16

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1093/jn/134.10.2509DOI Listing
October 2004

Rosiglitazone upregulates caveolin-1 expression in THP-1 cells through a PPAR-dependent mechanism.

J Lipid Res 2004 Nov 16;45(11):2015-24. Epub 2004 Aug 16.

Unitat de Farmacologia, Facultat de Farmàcia, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1194/jlr.M400049-JLR200DOI Listing
November 2004

Atorvastatin reduces CD68, FABP4, and HBP expression in oxLDL-treated human macrophages.

Biochem Biophys Res Commun 2004 May;318(1):265-74

Department of Pharmacology and Therapeutic Chemistry, School of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbrc.2004.04.021DOI Listing
May 2004

CD4 expression decrease by antisense oligonucleotides: inhibition of rat T CD4+ cell reactivity.

Oligonucleotides 2003 ;13(4):217-28

Department of Physiology-Division IV, Faculty of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.1089/154545703322460603DOI Listing
June 2005

The expression of retinoblastoma and Sp1 is increased by low concentrations of cyclin-dependent kinase inhibitors.

Eur J Biochem 2003 Dec;270(24):4809-22

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.1046/j.1432-1033.2003.03874.xDOI Listing
December 2003

An intron is required for dihydrofolate reductase protein stability.

J Biol Chem 2003 Oct 15;278(40):38292-300. Epub 2003 Jul 15.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona E-08028, Spain.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M212746200
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http://dx.doi.org/10.1074/jbc.M212746200DOI Listing
October 2003

Inhibition of CD4 expression by antisense oligonucleotides in PMA-treated lymphocytes.

Antisense Nucleic Acid Drug Dev 2002 Dec;12(6):399-410

Department of Physiology, Division IV, Faculty of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.1089/108729002321082474DOI Listing
December 2002

Transcriptional regulation of the human Sp1 gene promoter by the specificity protein (Sp) family members nuclear factor Y (NF-Y) and E2F.

Biochem J 2003 Apr;371(Pt 2):265-75

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1042/BJ20021166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1223280PMC
April 2003

Development and effects of immunoliposomes carrying an antisense oligonucleotide against DHFR RNA and directed toward human breast cancer cells overexpressing HER2.

Antisense Nucleic Acid Drug Dev 2002 Oct;12(5):311-25

Department of Biochemistry, School of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.1089/108729002761381294DOI Listing
October 2002