Carlos H Villa

Carlos H Villa

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Carlos H Villa

Carlos H Villa

Publications by authors named "Carlos H Villa"

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Vascular Targeting of Radiolabeled Liposomes with Bio-Orthogonally Conjugated Ligands: Single Chain Fragments Provide Higher Specificity than Antibodies.

Bioconjug Chem 2018 Nov 16;29(11):3626-3637. Epub 2018 Oct 16.

Department of Systems Pharmacology and Translational Therapeutics , Perelman School of Medicine , 3400 Civic Center Boulevard, Bldg 421 , Philadelphia , Pennsylvania 19104-5158 , United States.

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http://pubs.acs.org/doi/10.1021/acs.bioconjchem.8b00564
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http://dx.doi.org/10.1021/acs.bioconjchem.8b00564DOI Listing
November 2018

Rapid prediction of stem cell mobilization using volume and conductivity data from automated hematology analyzers.

Transfusion 2018 02 11;58(2):330-338. Epub 2017 Dec 11.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania.

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http://dx.doi.org/10.1111/trf.14449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803359PMC
February 2018

Targeting superoxide dismutase to endothelial caveolae profoundly alleviates inflammation caused by endotoxin.

J Control Release 2018 02 29;272:1-8. Epub 2017 Dec 29.

Department of Pharmacology, Center for Translational Targeted Therapeutics, Nanomedicine of the Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2017.12.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825285PMC
February 2018

Biocompatible coupling of therapeutic fusion proteins to human erythrocytes.

Blood Adv 2018 02;2(3):165-176

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; and.

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http://www.bloodadvances.org/lookup/doi/10.1182/bloodadvance
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http://dx.doi.org/10.1182/bloodadvances.2017011734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812327PMC
February 2018

Site-Specific Modification of Single-Chain Antibody Fragments for Bioconjugation and Vascular Immunotargeting.

Bioconjug Chem 2018 01 29;29(1):56-66. Epub 2017 Dec 29.

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine and ‡Department of Bioengineering, University of Pennsylvania , Philadelphia, Pennsylvania 19104, United States.

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http://dx.doi.org/10.1021/acs.bioconjchem.7b00592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477694PMC
January 2018

Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions.

Nanomedicine 2017 05 5;13(4):1495-1506. Epub 2017 Jan 5.

Department of Pharmacology and Center for Translational Targeted Therapeutics and Nanomedicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2016.12.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518469PMC
May 2017

Erythrocytes as Carriers for Drug Delivery in Blood Transfusion and Beyond.

Transfus Med Rev 2017 01 17;31(1):26-35. Epub 2016 Aug 17.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.tmrv.2016.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161683PMC
January 2017

Drug delivery by erythrocytes: "Primum non nocere".

Transfus Apher Sci 2016 Dec 31;55(3):275-280. Epub 2016 Oct 31.

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1016/j.transci.2016.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424546PMC
December 2016

Red blood cells: Supercarriers for drugs, biologicals, and nanoparticles and inspiration for advanced delivery systems.

Adv Drug Deliv Rev 2016 11 3;106(Pt A):88-103. Epub 2016 Mar 3.

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2016.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424548PMC
November 2016

Delivery of drugs bound to erythrocytes: new avenues for an old intravascular carrier.

Ther Deliv 2015 Jul;6(7):795-826

Department of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4155/tde.15.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712023PMC
July 2015

Encapsulation of α-Particle-Emitting 225Ac3+ Ions Within Carbon Nanotubes.

J Nucl Med 2015 Jun 30;56(6):897-900. Epub 2015 Apr 30.

Department of Chemistry, and the Smalley Institute for Nanoscale Science and Technology, Rice University, Houston, Texas

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http://jnm.snmjournals.org/cgi/doi/10.2967/jnumed.115.158311
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http://dx.doi.org/10.2967/jnumed.115.158311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863440PMC
June 2015

Nontranscriptional role of Hif-1α in activation of γ-secretase and notch signaling in breast cancer.

Cell Rep 2014 Aug 14;8(4):1077-92. Epub 2014 Aug 14.

Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA; Program of Pharmacology, Weill Graduate School of Medical Sciences of Cornell University, New York, NY 10021, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.07.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346175PMC
August 2014

Self-assembly of carbon nanotubes and antibodies on tumours for targeted amplified delivery.

Nat Nanotechnol 2013 Oct 29;8(10):763-71. Epub 2013 Sep 29.

1] Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA [2] Weill-Cornell Medical College, 468 East 68th Street, New York, New York 10065, USA [3].

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http://dx.doi.org/10.1038/nnano.2013.190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798027PMC
October 2013

Addition of plerixafor to mobilization regimens in autologous peripheral blood stem cell transplants does not affect the correlation of preharvest hematopoietic precursor cell enumeration with first-harvest CD34+ stem cell yield.

Biol Blood Marrow Transplant 2012 Dec 13;18(12):1867-75. Epub 2012 Jul 13.

Department of Pathology and Laboratory Medicine, University of Pennsylvania Health System, Philadelphia, USA.

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http://dx.doi.org/10.1016/j.bbmt.2012.07.002DOI Listing
December 2012

Selective killing of tumor neovasculature paradoxically improves chemotherapy delivery to tumors.

Cancer Res 2010 Nov 2;70(22):9277-86. Epub 2010 Nov 2.

Molecular Pharmacology and Chemistry Program, Cancer Biology and Genetics Program, and Departments of Medicine and Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-2029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058681PMC
November 2010

Imaging and treating tumor vasculature with targeted radiolabeled carbon nanotubes.

Int J Nanomedicine 2010 Oct 5;5:783-802. Epub 2010 Oct 5.

Department of Medicine and Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.2147/IJN.S13300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962274PMC
October 2010

Paradoxical glomerular filtration of carbon nanotubes.

Proc Natl Acad Sci U S A 2010 Jul 21;107(27):12369-74. Epub 2010 Jun 21.

Departments of Medicine, Radiology, Molecular Pharmacology and Chemistry or the Molecular Cytology Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0913667107
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http://dx.doi.org/10.1073/pnas.0913667107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901461PMC
July 2010

Conscripts of the infinite armada: systemic cancer therapy using nanomaterials.

Nat Rev Clin Oncol 2010 May 30;7(5):266-76. Epub 2010 Mar 30.

Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1038/nrclinonc.2010.38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411965PMC
May 2010

Synthesis and biodistribution of oligonucleotide-functionalized, tumor-targetable carbon nanotubes.

Nano Lett 2008 Dec;8(12):4221-8

Molecular Pharmacology and Chemistry Program and Departments of Medicine and Radiology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1021/nl801878dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059415PMC
December 2008

Targeted nanomaterials for radiotherapy.

Nanomedicine (Lond) 2007 Dec;2(6):805-15

Memorial Sloan Kettering Cancer Center, Molecular Pharmacology and Chemistry Program, New York, NY 10021, USA.

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http://dx.doi.org/10.2217/17435889.2.6.805DOI Listing
December 2007