Carlos Faro

Carlos Faro

UNVERIFIED PROFILE

Are you Carlos Faro?   Register this Author

Register author
Carlos Faro

Carlos Faro

Publications by authors named "Carlos Faro"

Are you Carlos Faro?   Register this Author

40Publications

582Reads

21Profile Views

Cardosin A endocytosis mediated by integrin leads to lysosome leakage and apoptosis of epithelial cells.

Proteins 2019 06 15;87(6):502-511. Epub 2019 Mar 15.

Protein Studies Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/prot.25672DOI Listing
June 2019

An atypical aspartic protease modulates lateral root development in Arabidopsis thaliana.

J Exp Bot 2019 Apr;70(7):2157-2171

Institute for Interdisciplinary Research, University of Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jxb/erz059DOI Listing
April 2019

Miniature cheeses made with blends of chymosin and a vegetable rennet from flowers of Silybum marianum: Enzymatic characterization of the flower-coagulant peptidase.

Food Chem 2018 Nov 4;266:223-231. Epub 2018 Jun 4.

CIPROVE-Centro Asociado CICPBA, Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, UNLP, Calle 47 y 115 S/N, B1900AJL La Plata, Argentina; CONICET, Argentina; Centre for Neuroscience and Cell Biology (CNC), University of Coimbra, 3004-517 Coimbra, Portugal. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.foodchem.2018.06.007DOI Listing
November 2018

Functional and structural characterization of synthetic cardosin B-derived rennet.

Appl Microbiol Biotechnol 2017 Sep 2;101(18):6951-6968. Epub 2017 Aug 2.

Biocant, Biotechnology Innovation Center, Parque Tecnológico de Cantanhede, Núcleo 4 Lote 8, 3060-197, Cantanhede, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00253-017-8445-8DOI Listing
September 2017

Biophysical characterization of laforin-carbohydrate interaction.

Biochem J 2016 Feb 17;473(3):335-45. Epub 2015 Nov 17.

Biocant-Biotechnology Innovation Center, Parque Tecnológico de Cantanhede, Núcleo 4, Lote 8-3060-197 Cantanhede, Portugal

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BJ20141555DOI Listing
February 2016

Structure of RC1339/APRc from Rickettsia conorii, a retropepsin-like aspartic protease.

Acta Crystallogr D Biol Crystallogr 2015 Oct 30;71(Pt 10):2109-18. Epub 2015 Sep 30.

Protein Structure Section, Macromolecular Crystallography Laboratory, National Cancer Institute, Frederick, MD 21702, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1107/S1399004715013905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601372PMC
October 2015

Engineering a cardosin B-derived rennet for sheep and goat cheese manufacture.

Appl Microbiol Biotechnol 2015 Jan 2;99(1):269-81. Epub 2014 Jul 2.

Biocant, Biotechnology Innovation Center, Parque Tecnológico de Cantanhede, Núcleo 4, Lote 3, 3060-197, Cantanhede, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00253-014-5902-5DOI Listing
January 2015

RC1339/APRc from Rickettsia conorii is a novel aspartic protease with properties of retropepsin-like enzymes.

PLoS Pathog 2014 Aug 21;10(8):e1004324. Epub 2014 Aug 21.

The Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal; Biocant, Biotechnology Innovation Center, Cantanhede, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1004324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140852PMC
August 2014

Dose-dependent inhibition of BACE-1 by the monoterpenoid 2,3,4,4-tetramethyl-5-methylenecyclopent-2-enone in cellular and mouse models of Alzheimer's disease.

J Nat Prod 2014 Jun 12;77(6):1275-9. Epub 2014 Jun 12.

Center of Pharmaceutical Studies, Faculty of Pharmacy, University of Coimbra , Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/np400903wDOI Listing
June 2014

Identification of DLEC1 D215N Somatic Mutation in Formalin Fixed Paraffin Embedded Melanoma and Melanocytic Nevi Specimens.

J Skin Cancer 2013 13;2013:469671. Epub 2013 Oct 13.

Serviço de Dermatologia, Centro Hospitalar e Universitário de Coimbra, Praceta Mota Pinto, 3000-375 Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2013/469671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810429PMC
November 2013

Molecular cloning and characterization of procirsin, an active aspartic protease precursor from Cirsium vulgare (Asteraceae).

Phytochemistry 2012 Sep 21;81:7-18. Epub 2012 Jun 21.

Laboratorio de Investigación de Proteínas Vegetales (LIPROVE), Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phytochem.2012.05.028DOI Listing
September 2012

Chlapsin, a chloroplastidial aspartic proteinase from the green algae Chlamydomonas reinhardtii.

Planta 2012 Jul 19;236(1):283-96. Epub 2012 Feb 19.

Biocant, Biotechnology Innovation Center, Molecular Biotechnology Unit, Parque Tecnológico de Cantanhede, Núcleo 4 Lote 3, 3060-197, Cantanhede, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00425-012-1605-2DOI Listing
July 2012

Shewasin A, an active pepsin homolog from the bacterium Shewanella amazonensis.

FEBS J 2011 Sep 11;278(17):3177-86. Epub 2011 Aug 11.

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1742-4658.2011.08243.x
Publisher Site
http://dx.doi.org/10.1111/j.1742-4658.2011.08243.xDOI Listing
September 2011

Self-assembled dextrin nanogel as protein carrier: controlled release and biological activity of IL-10.

Biotechnol Bioeng 2011 Aug 22;108(8):1977-86. Epub 2011 Mar 22.

Institute for Biotechnology and Bioengineering, Centre of Biological Engineering, Universidade do Minho, Campus de Gualtar, 4710-057 Braga, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bit.23125DOI Listing
August 2011

Expression of the functional carbohydrate-binding module (CBM) of human laforin.

Protein Expr Purif 2010 Dec 1;74(2):169-74. Epub 2010 Jul 1.

IBB-Institute for Biotechnology and Bioengineering, Centre of Biological Engineering, Universidade do Minho, Braga, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pep.2010.06.019DOI Listing
December 2010

Biological activity of heterologous murine interleukin-10 and preliminary studies on the use of a dextrin nanogel as a delivery system.

Int J Pharm 2010 Nov 9;400(1-2):234-42. Epub 2010 Sep 9.

Institute for Biotechnology and Bioengineering, Centre of Biological Engineering, Universidade do Minho, Campus de Gualtar, 4710-057, Braga, Portugal.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S037851731000670
Publisher Site
http://dx.doi.org/10.1016/j.ijpharm.2010.08.040DOI Listing
November 2010

Serine protease-mediated host invasion by the parasitic nematode Steinernema carpocapsae.

J Biol Chem 2010 Oct 23;285(40):30666-75. Epub 2010 Jul 23.

Departamento de Biologia, Universidade dos Açores, Centro de Investigação de Recursos Naturais, Apartado 1422, Ponta Delgada 9501-801, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M110.129346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945561PMC
October 2010

Escherichia coli expression, refolding and characterization of human laforin.

Protein Expr Purif 2010 Jun 10;71(2):195-9. Epub 2010 Feb 10.

Biocant, Molecular Biotechnology Unit, Parque Tecnológico de Cantanhede, Núcleo 4, Lote 3, Cantanhede, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pep.2010.02.004DOI Listing
June 2010

African swine fever virus p10 protein exhibits nuclear import capacity and accumulates in the nucleus during viral infection.

Vet Microbiol 2008 Jul 28;130(1-2):47-59. Epub 2007 Dec 28.

Centro de Neurociências e Biologia Celular, Universidade de Coimbra, 3004-517 Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vetmic.2007.12.010DOI Listing
July 2008

Characterization of recombinant CDR1, an Arabidopsis aspartic proteinase involved in disease resistance.

J Biol Chem 2007 Oct 24;282(43):31358-65. Epub 2007 Jul 24.

Departamento de Biologia Molecular e Biotecnologia, Centro de Neurociências e Biologia Celular, Universidade de Coimbra, Apt. 3126, Coimbra 3000, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M702477200DOI Listing
October 2007

Characterization and expression analysis of the aspartic protease gene family of Cynara cardunculus L.

FEBS J 2007 May 13;274(10):2523-39. Epub 2007 Apr 13.

Departamento de Biologia Molecular e Biotecnologia do Centro de Neurociências de Coimbra, Universidade de Coimbra, Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1742-4658.2007.05787.xDOI Listing
May 2007

Purification of a novel aminopeptidase from the pollen of Parietaria judaica that alters epithelial integrity and degrades neuropeptides.

J Allergy Clin Immunol 2006 Oct 4;118(4):878-84. Epub 2006 Aug 4.

Center for Neurosciences and Cell Biology, University of Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2006.05.029DOI Listing
October 2006

Aspartic proteinase content of the Arabidopsis genome.

Curr Protein Pept Sci 2005 Dec;6(6):493-500

Departamento Bioquímica, Faculdade de Ciencias e Tecnologia, Universidade de Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/138920305774933268DOI Listing
December 2005

Molecular analysis of the interaction between cardosin A and phospholipase D(alpha). Identification of RGD/KGE sequences as binding motifs for C2 domains.

FEBS J 2005 Nov;272(22):5786-98

Departamento de Biologia Molecular e Biotecnologia, Centro de Neurociências e Biologia Celular, Universidade de Coimbra and Departamento de Bioquímica, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1742-4658.2005.04967.xDOI Listing
November 2005

Molecular cloning of a potato leaf cDNA encoding an aspartic protease (StAsp) and its expression after P. infestans infection.

Plant Physiol Biochem 2005 Sep 31;43(9):882-9. Epub 2005 Aug 31.

Instituto de Investigaciones Biológicas, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata, CC 1245, 7600 Mar del Plata, Argentina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.plaphy.2005.07.004DOI Listing
September 2005

Activation, proteolytic processing, and peptide specificity of recombinant cardosin A.

J Biol Chem 2005 Apr 27;280(13):13047-54. Epub 2005 Jan 27.

Departamento de Bioquímica, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, Apartado 3126, P-3001-401 Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M412076200
Publisher Site
http://dx.doi.org/10.1074/jbc.M412076200DOI Listing
April 2005

A new method for C-terminal sequence analysis in the proteomic era.

Nat Methods 2005 Mar 17;2(3):193-200. Epub 2005 Feb 17.

Department of Biochemistry, Physiology and Microbiology, Laboratory of Protein Biochemistry and Protein Engineering, Ghent University, K.L. Ledeganckstraat 35, B-9000 Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nmeth738DOI Listing
March 2005

Downregulation of retinal GLUT1 in diabetes by ubiquitinylation.

Mol Vis 2004 Aug 30;10:618-28. Epub 2004 Aug 30.

Biomedical Institute for Research in Light and Image, Center of Ophthalmology, University of Coimbra, Coimbra, Portugal.

View Article

Download full-text PDF

Source
August 2004

Structure and function of plant aspartic proteinases.

Eur J Biochem 2004 Jun;271(11):2067-75

Departamento de Biologia Molecular e Biotecnologia, Centro de Neurociências e Biologia Celular, Universidade de Coimbra, 3000 Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1432-1033.2004.04136.x
Publisher Site
http://dx.doi.org/10.1111/j.1432-1033.2004.04136.xDOI Listing
June 2004

Transthyretin, a new cryptic protease.

J Biol Chem 2004 May 19;279(20):21431-8. Epub 2004 Mar 19.

Molecular Neurobiology, Instituto de Biologia Molecular e Celular, Rua Campo Alegre 823, 4150-180 Porto, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M402212200DOI Listing
May 2004

Pharmacological effects of extracts from Valeriana adscendens Trel. II. Effects on GABA uptake and amino acids.

Phytother Res 2003 Jun;17(6):661-4

Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, Fisciano (Salerno), Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ptr.1225DOI Listing
June 2003

Protein kinase C gamma associates directly with the GluR4 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subunit. Effect on receptor phosphorylation.

J Biol Chem 2003 Feb 5;278(8):6307-13. Epub 2002 Dec 5.

Center for Neuroscience and Cell Biology and Department of Biochemistry, University of Coimbra, 3004-517 Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M205587200DOI Listing
February 2003