Carlos Cordon-Cardo

Carlos Cordon-Cardo

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Carlos Cordon-Cardo

Carlos Cordon-Cardo

Publications by authors named "Carlos Cordon-Cardo"

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Intragenic antagonistic roles of protein and circRNA in tumorigenesis.

Cell Res 2019 Aug 17;29(8):628-640. Epub 2019 Jun 17.

Cancer Research Institute, Beth Israel Deaconess Cancer Center, Departments of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1038/s41422-019-0192-1DOI Listing
August 2019

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts.

J Vis Exp 2019 Jun 13(148). Epub 2019 Jun 13.

Department of Pathology, Icahn School of Medicine at Mount Sinai;

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http://dx.doi.org/10.3791/57011DOI Listing
June 2019

Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis.

J Clin Invest 2019 Jan 26;129(1):215-222. Epub 2018 Nov 26.

Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center (BIDMC), Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1172/JCI99699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307955PMC
January 2019

Development and validation of a novel automated Gleason grade and molecular profile that define a highly predictive prostate cancer progression algorithm-based test.

Prostate Cancer Prostatic Dis 2018 11 7;21(4):594-603. Epub 2018 Aug 7.

Department of Pathology, Icahn School of Medicine at Mt. Sinai, 1468 Madison Avenue, New York City, NY, 10029, USA.

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http://dx.doi.org/10.1038/s41391-018-0067-4DOI Listing
November 2018

Myocardial Amyloid Quantification with Look-Locker Magnetic Resonance Sequence in Cardiac Amyloidosis. Diagnostic Accuracy in Clinical Practice and Histological Validation.

J Card Fail 2018 02 8;24(2):78-86. Epub 2017 Aug 8.

The Zena and Michael A. Wiener Cardiovascular Institute/Marie-Josee and Henry R. Kravis Center for Cardiovascular Health, Icahn School of Medicine, New York, New York.

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http://dx.doi.org/10.1016/j.cardfail.2017.08.445DOI Listing
February 2018

Erratum: Retraction for Gonzalez et al., "p73α Regulation by Chk1 in Response to DNA Damage".

Mol Cell Biol 2017 Sep 28;37(18). Epub 2017 Aug 28.

Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021.

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http://dx.doi.org/10.1128/MCB.00365-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574037PMC
September 2017

Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel.

J Vis Exp 2017 09 8(127). Epub 2017 Sep 8.

Department of Pathology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai;

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http://dx.doi.org/10.3791/56327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607877PMC
September 2017

PTEN counteracts FBXL2 to promote IP3R3- and Ca-mediated apoptosis limiting tumour growth.

Nature 2017 06 14;546(7659):554-558. Epub 2017 Jun 14.

Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, 522 First Avenue, SRB 1107, New York, New York 10016, USA.

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http://dx.doi.org/10.1038/nature22965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627969PMC
June 2017

Targeting sarcoma tumor-initiating cells through differentiation therapy.

Stem Cell Res 2017 05 13;21:117-123. Epub 2017 Apr 13.

Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2017.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988213PMC
May 2017

Implementation of a Precision Pathology Program Focused on Oncology-Based Prognostic and Predictive Outcomes.

Mol Diagn Ther 2017 04;21(2):115-123

Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

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http://dx.doi.org/10.1007/s40291-016-0249-5DOI Listing
April 2017

Reappraising hyalinizing clear cell carcinoma: A population-based study with molecular confirmation.

Head Neck 2017 03 29;39(3):503-511. Epub 2016 Nov 29.

Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1002/hed.24637DOI Listing
March 2017

The role of GATA2 in lethal prostate cancer aggressiveness.

Nat Rev Urol 2017 Jan 22;14(1):38-48. Epub 2016 Nov 22.

Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

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http://dx.doi.org/10.1038/nrurol.2016.225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489122PMC
January 2017

Immunopathologic Assessment of PTEN Expression.

Methods Mol Biol 2016 ;1388:23-37

Department of Pathology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, 1194, New York, NY, 10029, USA.

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http://dx.doi.org/10.1007/978-1-4939-3299-3_3DOI Listing
December 2016

H-RAS mutation is a key molecular feature of pediatric urothelial bladder cancer. A detailed report of three cases.

J Pediatr Urol 2016 Apr 22;12(2):91.e1-7. Epub 2015 Oct 22.

Department of Pathology, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jpurol.2015.08.020DOI Listing
April 2016

Characterization of desmoglein expression in the normal prostatic gland. Desmoglein 2 is an independent prognostic factor for aggressive prostate cancer.

PLoS One 2014 4;9(6):e98786. Epub 2014 Jun 4.

Department of Pathology and Cell Biology, Columbia University, New York, New York, United States of America; Department of Urology, Columbia University, New York, New York, United States of America; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York, United States of America; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098786PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045811PMC
August 2015

PI3K/AKT pathway regulates E-cadherin and Desmoglein 2 in aggressive prostate cancer.

Cancer Med 2015 Aug 29;4(8):1258-71. Epub 2015 May 29.

Department of Pathology, Icahn School of Medicine at Mount Sinai, New York City, New York.

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http://dx.doi.org/10.1002/cam4.463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559037PMC
August 2015

Expression of the cancer testis antigen IGF2BP3 in colorectal cancers; IGF2BP3 holds promise as a specific immunotherapy target.

Oncoscience 2015 1;2(6):607-14. Epub 2015 Jul 1.

Division of Colon and Rectal Surgery, Department of Surgery, Mount Sinai Roosevelt Hospital Center, Suite 7B, New York, USA ; Icahn School of Medicine at Mount Sinai, New York, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506364PMC
http://dx.doi.org/10.18632/oncoscience.174DOI Listing
August 2015

ΔNp63 expression is a protective factor of progression in clinical high grade T1 bladder cancer.

J Urol 2015 Apr 28;193(4):1144-50. Epub 2014 Oct 28.

Department of Pathology, Columbia University, New York, New York; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2014.10.098DOI Listing
April 2015

A genetic platform to model sarcomagenesis from primary adult mesenchymal stem cells.

Cancer Discov 2015 Apr 22;5(4):396-409. Epub 2015 Jan 22.

Cancer Research Institute, Beth Israel Deaconess Cancer Center, Departments of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1158/2159-8290.CD-14-1022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418175PMC
April 2015

Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma.

Nat Commun 2015 Jan 22;6:6087. Epub 2015 Jan 22.

1] Barcelona-Clínic Liver Cancer Group (HCC Translational Research Laboratory, Liver Unit, Hepato-biliary Surgery), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic, CIBERehd, Universitat de Barcelona, Barcelona 08036, Spain [2] Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Medicine, Department of Pathology, Recanati Miller Transplantation Institute), Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York 10029, USA [3] Institució Catalana de Recerca i Estudis Avançats, Barcelona 08010, Spain.

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http://dx.doi.org/10.1038/ncomms7087DOI Listing
January 2015

Overcoming tumor heterogeneity in the molecular diagnosis of urological cancers.

Expert Rev Mol Diagn 2014 Nov;14(8):1023-31

Department of Pathology, Icahn School of Medicine, 1468 Madison Avenue, New York City, NY 10029, USA.

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http://dx.doi.org/10.1586/14737159.2014.965151DOI Listing
November 2014

Biomarkers for bladder cancer management: present and future.

Am J Clin Exp Urol 2014 5;2(1):1-14. Epub 2014 Apr 5.

Department of Pathology, Icahn School of Medicine at Mount Sinai New York City, New York.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219291PMC
November 2014

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia.

Nat Med 2014 Oct 7;20(10):1130-7. Epub 2014 Sep 7.

1] Institute for Cancer Genetics, Columbia University, New York, New York, USA. [2] Department of Pathology, Columbia University Medical Center, New York, New York, USA. [3] Department of Pediatrics, Columbia University Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1038/nm.3665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192073PMC
October 2014

Bladder cancers arise from distinct urothelial sub-populations.

Nat Cell Biol 2014 Oct 14;16(10):982-91, 1-5. Epub 2014 Sep 14.

Departments of Urology, Genetics &Development, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1038/ncb3038DOI Listing
October 2014

Defining the role of CD2 in disease progression and overall survival among patients with completely resected stage-II to -III cutaneous melanoma.

J Am Acad Dermatol 2014 Jun 31;70(6):1036-44. Epub 2014 Mar 31.

Department of Dermatology, Mount Sinai School of Medicine, New York, New York; Department of Hematology and Medical Oncology, Mount Sinai School of Medicine, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2014.01.914DOI Listing
June 2014

FBXW7 mutations in melanoma and a new therapeutic paradigm.

J Natl Cancer Inst 2014 Jun 16;106(6):dju107. Epub 2014 May 16.

Affiliations of authors: Department of Dermatology (ITY, SJA, AD, DB, JTC) and Department of Pathology (ITA, SJA, MC-M, AD, DB, CC-C, JTC), Icahn School of Medicine at Mount Sinai, New York, NY; Department of Biomedical Informatics (RDM, RR) and Department of Systems Biology (RDM, RR), Columbia University Medical Center, New York, NY; Department of Cancer Research, Skin Cancer Center Hornheide, Munster, Germany (GB); Department of Dermatology, New York University, New York, NY (IO).

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http://jnci.oxfordjournals.org/content/106/6/dju107.full.pdf
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http://jnci.oxfordjournals.org/cgi/doi/10.1093/jnci/dju107
Publisher Site
http://dx.doi.org/10.1093/jnci/dju107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081626PMC
June 2014

Genomic analysis in active surveillance: predicting high-risk disease using tissue biomarkers.

Curr Opin Urol 2014 May;24(3):303-10

Icahn School of Medicine at Mt. Sinai, Department of Pathology, New York, New York, USA.

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http://dx.doi.org/10.1097/MOU.0000000000000051DOI Listing
May 2014

RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis.

Cancer Discov 2014 Mar 20;4(3):318-33. Epub 2014 Jan 20.

1Cold Spring Harbor Laboratory, Cancer Center, Cold Spring Harbor; 2Department of Pathology and Laboratory Medicine, New York-Presbyterian Hospital, Weill Cornell Medical College; 3Mount Sinai School of Medicine, New York, New York; 4Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; and 5Unit for Laboratory Animal Medicine, Medical School, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084646PMC
March 2014

MAGE-A3 is highly expressed in a subset of colorectal cancer patients.

Cancer Immun 2012 28;12:16. Epub 2012 Dec 28.

Division of Colon and Rectal Surgery, Department of Surgery, St Luke's-Roosevelt Hospital Center, New York, NY 10019, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554221PMC
July 2013

Predicting high-risk disease using tissue biomarkers.

Curr Opin Urol 2013 May;23(3):245-51

Department of Pathology, Mt. Sinai School of Medicine, New York City, NY 10029-6574, USA.

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http://dx.doi.org/10.1097/MOU.0b013e32835f89ccDOI Listing
May 2013

Compound In Vivo Inactivation of Pml and p53 Uncovers a Functional Interaction in Angiosarcoma Suppression.

Genes Cancer 2012 Sep;3(9-10):599-603

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA ; Cancer Biology and Genetics Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1177/1947601912473604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591099PMC
September 2012

A BAC-based transgenic mouse specifically expresses an inducible Cre in the urothelium.

PLoS One 2012 9;7(4):e35243. Epub 2012 Apr 9.

Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035243PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322165PMC
August 2012

CpG ODN, Toll like receptor (TLR)-9 agonist, inhibits metastatic colon adenocarcinoma in a murine hepatic tumor model.

J Surg Res 2012 May 15;174(2):284-90. Epub 2011 Jan 15.

Department of Surgery and Institute of Basic Medical Science, Yonsei University, Wonju College of Medicine, Wonju, Korea.

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http://linkinghub.elsevier.com/retrieve/pii/S002248041001887
Publisher Site
http://dx.doi.org/10.1016/j.jss.2010.12.021DOI Listing
May 2012

PAX7-FKHR fusion gene inhibits myogenic differentiation via NF-kappaB upregulation.

Clin Transl Oncol 2012 Mar;14(3):197-206

School of Exercise Biomedical and Health Science, Edith Cowan University, Joondalup, Western Australia 6027, Australia.

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March 2012

A comparison of the outcomes of neoadjuvant and adjuvant chemotherapy for clinical T2-T4aN0-N2M0 bladder cancer.

Cancer 2012 Jan 29;118(2):358-64. Epub 2011 Jun 29.

Department of Urology, Columbia University Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1002/cncr.26278DOI Listing
January 2012

Predictive value of microtubule associated proteins tau and stathmin in patients with nonmuscle invasive bladder cancer receiving adjuvant intravesical taxane therapy.

J Urol 2011 Nov 23;186(5):2094-100. Epub 2011 Sep 23.

Department of Urology, Columbia University College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1016/j.juro.2011.06.051DOI Listing
November 2011

Personalized approach to prostate cancer prognosis.

Arch Esp Urol 2011 Oct;64(8):783-91

Aureon Biosciences Inc., Yonkers, New York 10701, USA.

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October 2011

Alternate PAX3 and PAX7 C-terminal isoforms in myogenic differentiation and sarcomagenesis.

Clin Transl Oncol 2011 Mar;13(3):194-203

School of Exercise Biomedical and Health Science, Edith Cowan University, Joondalup, Australia.

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http://dx.doi.org/10.1007/s12094-011-0640-yDOI Listing
March 2011

Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation.

Cancer Res 2011 Feb 28;71(3):964-75. Epub 2010 Dec 28.

Department of Cancer Biology and Oncology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-3172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033220PMC
February 2011

A Role for PML in Innate Immunity.

Genes Cancer 2011 Jan;2(1):10-9

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1177/1947601911402682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111006PMC
January 2011

Molecular pathways of urothelial development and bladder tumorigenesis.

Urol Oncol 2010 Jul-Aug;28(4):401-8

Department of Pathology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.urolonc.2009.04.019DOI Listing
November 2010

Impact of stromal sensitivity on radiation response of tumors implanted in SCID hosts revisited.

Cancer Res 2010 Oct 5;70(20):8179-86. Epub 2010 Oct 5.

Laboratory of Signal Transduction and Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center; Department of Pathology, Columbia University, New York, NY 10065, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-1871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976483PMC
October 2010

Galectin-3 expression is associated with bladder cancer progression and clinical outcome.

Tumour Biol 2010 Aug 17;31(4):277-85. Epub 2010 Apr 17.

Tumor Markers Group, Molecular Pathology Program, Spanish National Cancer Center, Madrid, Spain.

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http://dx.doi.org/10.1007/s13277-010-0033-9DOI Listing
August 2010

Mouse models of human bladder cancer as a tool for drug discovery.

Curr Protoc Pharmacol 2010 Jun;Chapter 14:Unit14.14

Department of Urology, Columbia University Medical Center, Herbert Irving Comprehensive Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1002/0471141755.ph1414s49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272628PMC
June 2010

Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.

Nature 2010 Mar;464(7287):374-9

Cancer Biology and Genetics Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nature08815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928066PMC
March 2010