Carlos A Guzman

Carlos A Guzman

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Carlos A Guzman

Carlos A Guzman

Publications by authors named "Carlos A Guzman"

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Influenza-Activated ILC1s Contribute to Antiviral Immunity Partially Influenced by Differential GITR Expression.

Front Immunol 2018 22;9:505. Epub 2018 Mar 22.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://journal.frontiersin.org/article/10.3389/fimmu.2018.00
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http://dx.doi.org/10.3389/fimmu.2018.00505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874297PMC
May 2019

Functional and immunogenic characterization of diverse HCV glycoprotein E2 variants.

J Hepatol 2019 Apr 13;70(4):593-602. Epub 2018 Nov 13.

Institute of Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research; a Joint Venture between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI), Hannover, Germany; German Centre for Infection Research (DZIF), partner site Hannover-Braunschweig, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01688278183252
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http://dx.doi.org/10.1016/j.jhep.2018.11.003DOI Listing
April 2019

The Combination Vaccine Adjuvant System Alum/c-di-AMP Results in Quantitative and Qualitative Enhanced Immune Responses Post Immunization.

Front Cell Infect Microbiol 2019 19;9:31. Epub 2019 Feb 19.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://dx.doi.org/10.3389/fcimb.2019.00031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390046PMC
February 2019

Mannose Metabolism Is Essential for Th1 Cell Differentiation and IFN-γ Production.

J Immunol 2018 09 20;201(5):1400-1411. Epub 2018 Jul 20.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.

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http://dx.doi.org/10.4049/jimmunol.1700042DOI Listing
September 2018

Respiratory Carriage is Associated with Broad Phenotypic Alterations of Peripheral CD4⁺CD25⁺ T Cells and Differentially Affects Immune Responses to Secondary Non-Infectious and Infectious Stimuli in Mice.

Int J Mol Sci 2018 Sep 1;19(9). Epub 2018 Sep 1.

Infection Immunology Group, Institute of Medical Microbiology, Infection Control and Prevention, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 39120 Magdeburg, Germany.

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http://dx.doi.org/10.3390/ijms19092602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165163PMC
September 2018

Rapid In Vivo Assessment of Adjuvant's Cytotoxic T Lymphocytes Generation Capabilities for Vaccine Development.

J Vis Exp 2018 06 19(136). Epub 2018 Jun 19.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research.

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http://dx.doi.org/10.3791/57401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101763PMC
June 2018

Dual dye in-vivo imaging of differentially charged PLGA carriers reveals antigen-depot effect, leading to improved immune responses in preclinical models.

Eur J Pharm Sci 2018 May 13;117:88-97. Epub 2018 Feb 13.

Institute of Pharmacy, Faculty I of Natural Sciences, Martin-Luther-University Halle-Wittenberg, Wolfgang-Langenbeck-Str. 4, 06120 Halle/Saale, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejps.2018.01.040DOI Listing
May 2018

In Silico Vaccine Strain Prediction for Human Influenza Viruses.

Trends Microbiol 2018 02 9;26(2):119-131. Epub 2017 Oct 9.

Department for Computational Biology of Infection Research, Helmholtz Centre for Infection Research, Braunschweig, Germany; German Centre for Infection Research (DZIF). Electronic address:

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http://dx.doi.org/10.1016/j.tim.2017.09.001DOI Listing
February 2018

Self-Replicating RNA Vaccine Delivery to Dendritic Cells.

Methods Mol Biol 2017 ;1499:37-75

Institute of Virology and Immunology (IVI), Sensemattstrasse 293, CH-3147, Mittelhäusern, Switzerland.

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http://dx.doi.org/10.1007/978-1-4939-6481-9_3DOI Listing
January 2018

Bivalent mucosal peptide vaccines administered using the LCP carrier system stimulate protective immune responses against Streptococcus pyogenes infection.

Nanomedicine 2017 Nov 5;13(8):2463-2474. Epub 2017 Sep 5.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.nano.2017.08.015DOI Listing
November 2017

Self-replicating RNA vaccine functionality modulated by fine-tuning of polyplex delivery vehicle structure.

J Control Release 2017 Nov 19;266:256-271. Epub 2017 Sep 19.

Institute of Virology and Immunology (IVI), Sensemattstrasse 293, CH-3147 Mittelhäusern, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S01683659173085
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http://dx.doi.org/10.1016/j.jconrel.2017.09.018DOI Listing
November 2017

Intranasal vaccination with an adjuvanted polyphosphazenes nanoparticle-based vaccine formulation stimulates protective immune responses in mice.

Nanomedicine 2017 Oct 1;13(7):2169-2178. Epub 2017 Jun 1.

Helmholtz Center for Infection Research (HZI), Department of Vaccinology and Applied Microbiology, Braunschweig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2017.05.012DOI Listing
October 2017

Roads to advanced vaccines: influenza case study.

Microb Biotechnol 2017 09 15;10(5):1036-1040. Epub 2017 Aug 15.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, D-38124, Braunschweig, Germany.

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http://dx.doi.org/10.1111/1751-7915.12835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609253PMC
September 2017

Role of Autophagy in HIV-1 Matrix Protein p17-Driven Lymphangiogenesis.

J Virol 2017 08 27;91(16). Epub 2017 Jul 27.

Department of Molecular and Translational Medicine, University of Brescia Medical School, Brescia, Italy

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http://dx.doi.org/10.1128/JVI.00801-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533914PMC
August 2017

Type I IFN and not TNF, is Essential for Cyclic Di-nucleotide-elicited CTL by a Cytosolic Cross-presentation Pathway.

EBioMedicine 2017 Aug 19;22:100-111. Epub 2017 Jul 19.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.ebiom.2017.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552247PMC
August 2017

Cyclic dinucleotides modulate induced type I IFN responses in innate immune cells by degradation of STING.

FASEB J 2017 07 10;31(7):3107-3115. Epub 2017 Apr 10.

Vaccinology Research Group, Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany;

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http://dx.doi.org/10.1096/fj.201601093RDOI Listing
July 2017

New Horizons in the Development of Novel Needle-Free Immunization Strategies to Increase Vaccination Efficacy.

Curr Top Microbiol Immunol 2016 ;398:207-234

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany.

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http://dx.doi.org/10.1007/82_2016_495DOI Listing
June 2017

Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against infection.

NPJ Vaccines 2017 10;2. Epub 2017 Apr 10.

Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Cátedra de Inmunología and Instituto de Estudios de la Inmunidad Humoral (IDEHU), UBA-CONICET, Buenos Aires, Argentina.

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http://dx.doi.org/10.1038/s41541-017-0010-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604744PMC
April 2017

Targeted antigen delivery to dendritic cells elicits robust antiviral T cell-mediated immunity in the liver.

Sci Rep 2017 03 7;7:43985. Epub 2017 Mar 7.

Immune Regulation Group, Helmholtz Centre for Infection Research, Braunschweig, Germany &Infection Immunology Group, Institute of Medical Microbiology, Infection Control and Prevention, Medical Faculty of the Otto-von-Guericke University Magdeburg, Magdeburg, Germany.

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http://dx.doi.org/10.1038/srep43985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339819PMC
March 2017

A New RNA-Based Adjuvant Enhances Virus-Specific Vaccine Responses by Locally Triggering TLR- and RLH-Dependent Effects.

J Immunol 2017 02 11;198(4):1595-1605. Epub 2017 Jan 11.

Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a Joint Venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, D-30625 Hannover, Germany;

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http://dx.doi.org/10.4049/jimmunol.1601129DOI Listing
February 2017

Immunization with Tc52 or its amino terminal domain adjuvanted with c-di-AMP induces Th17+Th1 specific immune responses and confers protection against Trypanosoma cruzi.

PLoS Negl Trop Dis 2017 02 24;11(2):e0005300. Epub 2017 Feb 24.

Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Cátedra de Inmunología and Instituto de Estudios de la Inmunidad Humoral (IDEHU), UBA-CONICET, Buenos Aires, Argentina.

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http://dx.doi.org/10.1371/journal.pntd.0005300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342303PMC
February 2017

Rodents as pre-clinical models for predicting vaccine performance in humans.

Expert Rev Vaccines 2015 ;14(9):1213-25

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany.

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May 2016

Polyethylenimine-based polyplex delivery of self-replicating RNA vaccines.

Nanomedicine 2016 Apr 1;12(3):711-722. Epub 2015 Dec 1.

Institute of Virology and Immunology (IVI), Mittelhäusern, Switzerland.

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http://dx.doi.org/10.1016/j.nano.2015.11.001DOI Listing
April 2016

TRANSVAC research infrastructure - Results and lessons learned from the European network of vaccine research and development.

Vaccine 2015 Oct 8;33(41):5481-5487. Epub 2015 Feb 8.

European Vaccine Initiative, UniversitätsKlinikum Heidelberg, Im Neuenheimer Feld 326 - 3.OG, 69120, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.01.079DOI Listing
October 2015

Induction of CD4(+) and CD8(+) anti-tumor effector T cell responses by bacteria mediated tumor therapy.

Int J Cancer 2015 Oct 9;137(8):2019-28. Epub 2015 May 9.

Department of Molecular Immunology, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany.

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http://doi.wiley.com/10.1002/ijc.29567
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http://dx.doi.org/10.1002/ijc.29567DOI Listing
October 2015

Modeling Influenza Virus Infection: A Roadmap for Influenza Research.

Viruses 2015 Oct 12;7(10):5274-304. Epub 2015 Oct 12.

Systems Medicine of Infectious Diseases, Department of Systems Immunology and Braunschweig Integrated Centre of Systems Biology, Helmholtz Centre for Infection Research, Braunschweig 38124, Germany.

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http://dx.doi.org/10.3390/v7102875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632383PMC
October 2015

Big Data in Vaccinology: Introduction and section summaries.

Vaccine 2015 Sep 2;33(40):5237-40. Epub 2015 May 2.

Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.vaccine.2015.04.078DOI Listing
September 2015

Activated NKT cells imprint NK-cell differentiation, functionality and education.

Eur J Immunol 2015 Jun 27;45(6):1794-807. Epub 2015 Apr 27.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://doi.wiley.com/10.1002/eji.201445209
Publisher Site
http://dx.doi.org/10.1002/eji.201445209DOI Listing
June 2015

Inverse micellar sugar glass (IMSG) nanoparticles for transfollicular vaccination.

J Control Release 2015 May 18;206:140-52. Epub 2015 Mar 18.

Saarland University, Biopharmaceutics and Pharmaceutical Technology, Saarbruecken, Germany; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Department of Drug Delivery, Helmholtz Centre for Infection Research (HZI), Saarland University, Saarbruecken, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2015.03.017DOI Listing
May 2015

Oral multicomponent DNA vaccine delivered by attenuated Salmonella elicited immunoprotection against American trypanosomiasis.

J Infect Dis 2015 Mar 25;211(5):698-707. Epub 2014 Aug 25.

Cátedra de Inmunología and Instituto de Estudios de la Inmunidad Humoral Dr. R. A. Margni, Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad de Buenos Aires (CONICET-UBA), Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires Instituto de Microbiología y Parasitología Médica (IMPaM), UBA-CONICET and Departamento de Microbiología, Parasitología e Inmunología, Facultad de Medicina, UBA.

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http://dx.doi.org/10.1093/infdis/jiu480DOI Listing
March 2015

Evaluation of invalid vaccine doses in 31 countries of the WHO African Region.

Vaccine 2015 Feb 15;33(7):892-901. Epub 2014 Dec 15.

Department of Epidemiology, Helmholtz Centre for Infection Research, Braunschweig, Germany; Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1016/j.vaccine.2014.10.089DOI Listing
February 2015

The mucosal adjuvant cyclic di-AMP exerts immune stimulatory effects on dendritic cells and macrophages.

PLoS One 2014 22;9(4):e95728. Epub 2014 Apr 22.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0095728PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996008PMC
January 2015

Efficient nanoparticle-mediated needle-free transcutaneous vaccination via hair follicles requires adjuvantation.

Nanomedicine 2015 Jan 6;11(1):147-54. Epub 2014 Sep 6.

Helmholtz Center for Infection Research Braunschweig, Department of Vaccinology and Applied Microbiology, Braunschweig, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15499634140043
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http://dx.doi.org/10.1016/j.nano.2014.08.009DOI Listing
January 2015

Intranasal formulations: promising strategy to deliver vaccines.

Expert Opin Drug Deliv 2014 Oct 25;11(10):1619-34. Epub 2014 Jun 25.

Helmholtz Centre for Infection Research, Department of Vaccinology and Applied Microbiology , Inhoffenstrasse 7, 38124 Braunschweig , Germany.

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http://dx.doi.org/10.1517/17425247.2014.931936DOI Listing
October 2014

Tc52 amino-terminal-domain DNA carried by attenuated Salmonella enterica serovar Typhimurium induces protection against a Trypanosoma cruzi lethal challenge.

Infect Immun 2014 Oct 28;82(10):4265-75. Epub 2014 Jul 28.

Cátedra de Inmunología and Instituto de Estudios de la Inmunidad Humoral, UBA-CONICET, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina Instituto de Microbiología y Parasitología Médica, UBA-CONICET, and Departamento de Microbiología, Parasitología e Inmunología, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina

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http://dx.doi.org/10.1128/IAI.02190-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187887PMC
October 2014

Gene Expression Driven by a Strong Viral Promoter in MVA Increases Vaccination Efficiency by Enhancing Antibody Responses and Unmasking CD8⁺ T Cell Epitopes.

Vaccines (Basel) 2014 Jul 22;2(3):581-600. Epub 2014 Jul 22.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, D-38124 Braunschweig, Germany.

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http://dx.doi.org/10.3390/vaccines2030581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494220PMC
July 2014

TRANSVAC workshop on standardisation and harmonisation of analytical platforms for HIV, TB and malaria vaccines: 'how can big data help?'.

Vaccine 2014 Jul 17;32(35):4365-8. Epub 2014 Jun 17.

Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2014.06.014DOI Listing
July 2014

Vaccine adjuvants: key tools for innovative vaccine design.

Curr Top Med Chem 2013 ;13(20):2562-80

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7 38124 Braunschweig, Germany.

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June 2014

A new adjuvanted nanoparticle-based H1N1 influenza vaccine induced antigen-specific local mucosal and systemic immune responses after administration into the lung.

Vaccine 2014 May 13;32(26):3216-22. Epub 2014 Apr 13.

Fraunhofer Institute for Toxicology and Experimental Medicine, Nikolai-Fuchs-Straße 1, 30625 Hannover, Germany, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Centre for Lung Research (DZL); Institute of Immunology, Hannover Medical School, Hannover, Germany. Electronic address:

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http://www.pfizerpro.com.co/sites/g/files/g10013506/f/public
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http://linkinghub.elsevier.com/retrieve/pii/S0264410X1400513
Publisher Site
http://dx.doi.org/10.1016/j.vaccine.2014.04.011DOI Listing
May 2014

Effects of aging on influenza virus infection dynamics.

J Virol 2014 Apr 29;88(8):4123-31. Epub 2014 Jan 29.

Department of Systems Immunology and Braunschweig Integrated Centre of Systems Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://dx.doi.org/10.1128/JVI.03644-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993746PMC
April 2014

HIV-1 matrix protein p17 promotes lymphangiogenesis and activates the endothelin-1/endothelin B receptor axis.

Arterioscler Thromb Vasc Biol 2014 Apr 30;34(4):846-56. Epub 2014 Jan 30.

From the Microbiology Section, Department of Molecular and Translational Medicine (F.C., C.G., D.B., S.Z., S.F., A.C.) and Section of Vascular Surgery, Department of Medical and Surgical Sciences (E.C.), University of Brescia, Brescia, Italy; Animal Models and Retroviral Vaccine Section, National Cancer Institute, National Institutes of Health, Bethesda, MD (F.C.); Department of Vaccinology and Applied Microbiology, Helmholtz Centre of Infection Research, Braunschweig, Germany (C.R., K.S., C.A.G.); Department of Pharmaco-Biology, University of Calabria, Arcavacata di Rende (Cosenza), Italy (S.M.); and School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom (M.S.).

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http://dx.doi.org/10.1161/ATVBAHA.113.302478DOI Listing
April 2014

HLA-universal platelet transfusions prevent platelet refractoriness in a mouse model.

Hum Gene Ther 2013 Dec 7;24(12):1018-28. Epub 2013 Nov 7.

1 Institute for Transfusion Medicine, Hannover Medical School , 30625 Hannover, Germany .

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http://dx.doi.org/10.1089/hum.2013.074DOI Listing
December 2013

Purification of hepatitis B surface antigen virus-like particles from recombinant Pichia pastoris and in vivo analysis of their immunogenic properties.

J Chromatogr B Analyt Technol Biomed Life Sci 2013 Dec 27;940:104-11. Epub 2013 Sep 27.

Department of Structural Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany; International Centre for Genetic Engineering and Biotechnology, New Delhi, India; Technology Research Centre, Department of Chemical, Biochemical and Environmental Engineering, University of Maryland Baltimore County, Baltimore, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2013.09.030DOI Listing
December 2013

A study of Chitosan and c-di-GMP as mucosal adjuvants for intranasal influenza H5N1 vaccine.

Influenza Other Respir Viruses 2013 Nov 21;7(6):1181-93. Epub 2012 Nov 21.

Influenza Centre, The Gade Institute, University of Bergen, Bergen, NorwayDepartment of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, GermanyUniversity of Siena, Siena, ItalyVisMederi, Siena, ItalyArchimedes Development Ltd., Reading, UKDepartment of Research and Development, Haukeland University Hospital, Bergen, Norway.

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http://dx.doi.org/10.1111/irv.12056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634239PMC
November 2013

Non-invasive delivery of nanoparticles to hair follicles: a perspective for transcutaneous immunization.

Vaccine 2013 Jul 2;31(34):3442-51. Epub 2013 Jan 2.

Saarland University, Biopharmaceutics and Pharmaceutical Technology, Saarbruecken, Germany.

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http://dx.doi.org/10.1016/j.vaccine.2012.12.048DOI Listing
July 2013

Vaccines: from empirical development to rational design.

PLoS Pathog 2012 8;8(11):e1003001. Epub 2012 Nov 8.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://dx.doi.org/10.1371/journal.ppat.1003001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493475PMC
April 2013

Development and characterization of attenuated metabolic mutants of Bordetella bronchiseptica for applications in vaccinology.

Environ Microbiol 2013 Jan 7;15(1):64-76. Epub 2012 Jun 7.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, D-38124 Braunschweig, Germany.

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http://dx.doi.org/10.1111/j.1462-2920.2012.02779.xDOI Listing
January 2013

Toll-like receptor-2 agonist-allergen coupling efficiently redirects Th2 cell responses and inhibits allergic airway eosinophilia.

Am J Respir Cell Mol Biol 2012 Dec 6;47(6):852-63. Epub 2012 Sep 6.

Department for Clinical Immunology and Rheumatology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1165/rcmb.2011-0414OCDOI Listing
December 2012

HIV-1 matrix protein p17 promotes angiogenesis via chemokine receptors CXCR1 and CXCR2.

Proc Natl Acad Sci U S A 2012 Sep 17;109(36):14580-5. Epub 2012 Aug 17.

Section of Microbiology, Department of Experimental and Applied Medicine, Medical School, University of Brescia, 25123 Brescia, Italy.

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http://dx.doi.org/10.1073/pnas.1206605109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437870PMC
September 2012

Lymph node-derived lymphatic endothelial cells express functional costimulatory molecules and impair dendritic cell-induced allogenic T-cell proliferation.

FASEB J 2012 Jul 29;26(7):2835-46. Epub 2012 Mar 29.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre of Infection Research, Braunschweig, Germany.

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http://www.fasebj.org/doi/10.1096/fj.12-205278
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http://dx.doi.org/10.1096/fj.12-205278DOI Listing
July 2012

NKT cell stimulation with α-galactosylceramide results in a block of Th17 differentiation after intranasal immunization in mice.

PLoS One 2012 26;7(1):e30382. Epub 2012 Jan 26.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030382PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266900PMC
June 2012

Cyclic di-nucleotides: new era for small molecules as adjuvants.

Microb Biotechnol 2012 Mar 29;5(2):168-76. Epub 2011 Sep 29.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.

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http://doi.wiley.com/10.1111/j.1751-7915.2011.00306.x
Publisher Site
http://dx.doi.org/10.1111/j.1751-7915.2011.00306.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815777PMC
March 2012

Peritoneal cavity is dominated by IFNγ-secreting CXCR3+ Th1 cells.

PLoS One 2011 18;6(7):e18032. Epub 2011 Jul 18.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0018032PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138734PMC
November 2011

Exploitation of prokaryotic expression systems based on the salicylate-dependent control circuit encompassing nahR/P(sal)::xylS2 for biotechnological applications.

Bioeng Bugs 2010 Jul-Aug;1(4):244-51. Epub 2010 Jan 12.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://dx.doi.org/10.4161/bbug.1.4.11247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026463PMC
September 2011

Bis-(3',5')-cyclic dimeric adenosine monophosphate: strong Th1/Th2/Th17 promoting mucosal adjuvant.

Vaccine 2011 Jul 25;29(32):5210-20. Epub 2011 May 25.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.vaccine.2011.05.026DOI Listing
July 2011

Gene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase.

J Clin Immunol 2011 Jun 3;31(3):498-508. Epub 2011 Feb 3.

Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, 110 070, New Delhi, India.

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http://dx.doi.org/10.1007/s10875-010-9506-2DOI Listing
June 2011

Immune modulators with defined molecular targets: cornerstone to optimize rational vaccine design.

Adv Exp Med Biol 2009 ;655:171-88

Department of Vaccinology and Applied Micobiology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, D-38124, Braunschweig, Germany.

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http://dx.doi.org/10.1007/978-1-4419-1132-2_13DOI Listing
August 2010

Redirection of the immune response to the functional catalytic domain of the cystein proteinase cruzipain improves protective immunity against Trypanosoma cruzi infection.

J Infect Dis 2010 Jul;202(1):136-44

Cátedra de Inmunología and Instituto de Estudios de la Inmunidad Humoral (IDEHU), Universidad de BuenosAires, 1113 Buenos Aires, Argentina.

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http://dx.doi.org/10.1086/652872DOI Listing
July 2010

A Toll-like receptor 2/6 agonist reduces allergic airway inflammation in chronic respiratory sensitisation to Timothy grass pollen antigens.

Int Arch Allergy Immunol 2010 16;152(2):131-9. Epub 2009 Dec 16.

Department of Immunology, Allergology and Immunotoxicology, Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.

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http://dx.doi.org/10.1159/000265534DOI Listing
June 2010

Modified vaccinia virus Ankara exerts potent immune modulatory activities in a murine model.

PLoS One 2010 Jun 30;5(6):e11400. Epub 2010 Jun 30.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0011400PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900180PMC
June 2010

The member of the cyclic di-nucleotide family bis-(3', 5')-cyclic dimeric inosine monophosphate exerts potent activity as mucosal adjuvant.

Vaccine 2010 Mar 7;28(10):2249-58. Epub 2010 Jan 7.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre of Infection Research, Inhoffenstrasse 7, D-38124 Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.vaccine.2009.12.045DOI Listing
March 2010

Subchronic toxicological evaluation of brea gum (Parkinsonia preacox) as a food additive in BALB/c mice.

Drug Chem Toxicol 2009 ;32(4):307-11

Facultad de Ciencias Agropecuarias, Universidad Nacional de Córdoba, Córdoba, Argentina.

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http://dx.doi.org/10.1080/01480540902976903DOI Listing
January 2010

Intranasal immunization promotes th17 immune responses.

J Immunol 2009 Dec 4;183(11):6933-8. Epub 2009 Nov 4.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany.

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http://dx.doi.org/10.4049/jimmunol.0901144DOI Listing
December 2009

Pidotimod promotes functional maturation of dendritic cells and displays adjuvant properties at the nasal mucosa level.

Int Immunopharmacol 2009 Nov 25;9(12):1366-73. Epub 2009 Aug 25.

Department of Experimental and Applied Medicine, Section of Microbiology, University of Brescia, Medical School, Brescia, Italy.

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http://dx.doi.org/10.1016/j.intimp.2009.08.010DOI Listing
November 2009

HIV pseudovirion vaccine exposing Env "fusion intermediates"-response to immunisation in human CD4/CCR5-transgenic rats.

Vaccine 2009 Apr 13;27(16):2202-12. Epub 2009 Feb 13.

Forschungsschwerpunkt Infektion und Krebs, F020, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 242, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.vaccine.2009.02.014DOI Listing
April 2009

The toll-like receptor 2/6 ligand MALP-2 reduces the viability of Mycobacterium tuberculosis in murine macrophages.

Open Microbiol J 2009 Apr 3;3:47-52. Epub 2009 Apr 3.

Department of Infectious, Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.2174/1874285800903010047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685717PMC
April 2009