Carlo Napolitano, MD, PhD - Molecular Cardiology IRCCS Fondazione Salvatore Maugeri

Carlo Napolitano

MD, PhD

Molecular Cardiology IRCCS Fondazione Salvatore Maugeri

Pavia | Italy

Main Specialties: Cardiovascular Disease

Additional Specialties: Cardiology

Carlo Napolitano, MD, PhD - Molecular Cardiology IRCCS Fondazione Salvatore Maugeri

Carlo Napolitano

MD, PhD

Introduction

Primary Affiliation: Molecular Cardiology IRCCS Fondazione Salvatore Maugeri - Pavia , Italy

Specialties:

Additional Specialties:


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Publications

98Publications

2037Reads

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2679PubMed Central Citations

Unusual retrospective prenatal findings in a male newborn with Timothy syndrome type 1.

Eur J Med Genet 2015 Jun-Jul;58(6-7):332-5. Epub 2015 Apr 13.

Service of Pediatric Genetics and Cytogenetic Unit, Center for Registry and Research in Congenital Anomalies (CRIAC), "Dr. Juan I. Menchaca" Civil Hospital of Guadalajara, Mexico.

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http://dx.doi.org/10.1016/j.ejmg.2015.04.001DOI Listing
March 2016
6 Reads
3 Citations
1.490 Impact Factor

Flecainide monotherapy for catecholaminergic polymorphic ventricular tachycardia: Perspectives and limitations.

Authors:
Carlo Napolitano

Heart Rhythm 2016 Feb 21;13(2):614-5. Epub 2015 Oct 21.

Molecular Cardiology, IRCCS Fondazione Salvatore Maugeri, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2015.10.030DOI Listing
February 2016
22 Reads
1 Citation
5.080 Impact Factor

Programmed Ventricular Stimulation for Risk Stratification in the Brugada Syndrome: A Pooled Analysis.

Circulation 2016 Feb 21;133(7):622-30. Epub 2016 Jan 21.

From Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA (J.S.); Service de Cardiologue du CHU de Nantes, CHU de Nantes, Hôpital Nord, Nantes, France (V.P.); Molecular Cardiology, IRCCS Fondazione Salvatore Maugeri, Pavia, Italy (A.M., C.N., S.G.P.); Dipartimento di Medicina, Molecolare Università di Pavia, Pavia, Italy (S.G.P.); Division of Cardiology, Casa di Cura Pederzoli, Peschiera del Garda, Verona, Italy (P.D.); Arrhythmia Unit, Cardiovascular Surgery and Cardiology Institute, Havana, Cuba (J.C.H.); Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan (K.O., I.W.); Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy (A.Z., D.C.); Institut Universitaire de Cardiologie et Pneumologie de Québec, Quebec City, QC, Canada (J.C., I.N.); Department of Electrophysiology and Pacing, Onassis Cardiac Surgery Center, Athens, Greece (A.K., G.T.); Boston University and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA (X.Y.); Cardiovascular Research Center and Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston (D.J.M., P.T.E., S.A.L.); Heart Centre AMC, Department of Clinical and Experimental Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands (A.W.); Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders, Jeddah, Kingdom of Saudi Arabia (A.W.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S.); First Department of Medicine-Cardiology, University Medical Centre Mannheim, Mannheim, Germany (M.B.); DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Mannheim, Germany (M.B.); Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA (P.T.E., S.A.L.); Department of Cardiology, General Hospital of Conegliano, Conegliano, Treviso, Italy (G.A.); and Lankenau I

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http://circ.ahajournals.org/content/early/2016/01/21/CIRCULA
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http://circ.ahajournals.org/lookup/doi/10.1161/CIRCULATIONAH
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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.017885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758872PMC
February 2016
69 Reads
17 Citations
14.430 Impact Factor

From decision to shared-decision: Introducing patients' preferences into clinical decision analysis.

Artif Intell Med 2015 Sep 1;65(1):19-28. Epub 2014 Nov 1.

Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Via Ferrata 5, 27100 Pavia, Italy.

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http://dx.doi.org/10.1016/j.artmed.2014.10.004DOI Listing
September 2015
20 Reads
3 Citations
2.020 Impact Factor

Genetic modulators of the phenotype in the long QT syndrome: state of the art and clinical impact.

Curr Opin Genet Dev 2015 Aug 2;33:17-24. Epub 2015 Aug 2.

Department of Molecular Medicine University of Pavia, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2015.06.009DOI Listing
August 2015
3 Reads
4 Citations
7.574 Impact Factor

Graphical representation of life paths to better convey results of decision models to patients.

Med Decis Making 2015 04 14;35(3):398-402. Epub 2015 Jan 14.

University of Pavia, Italy (SR, CR, LS, EP, SQ)

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http://dx.doi.org/10.1177/0272989X14565822DOI Listing
April 2015
4 Reads
2 Citations
3.240 Impact Factor

Patient-tailored workflow patterns from clinical practice guidelines recommendations.

Stud Health Technol Inform 2013 ;192:392-6

Dipartimento di Ingegneria Industriale e dell'Informazione, University of Pavia, Italy.

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April 2015
15 Reads
2 Citations

[Role of standard resting ECG in the assessment of sudden cardiac death risk].

G Ital Cardiol (Rome) 2014 Dec;15(12):670-7

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http://dx.doi.org/10.1714/1718.18768DOI Listing
December 2014
3 Reads
1 Citation

Single delivery of an adeno-associated viral construct to transfer the CASQ2 gene to knock-in mice affected by catecholaminergic polymorphic ventricular tachycardia is able to cure the disease from birth to advanced age.

Circulation 2014 Jun 2;129(25):2673-81. Epub 2014 Jun 2.

From Molecular Cardiology, IRCCS Fondazione Salvatore Maugeri, Pavia, Italy (M.D., R.B., F.L., V.C.D.G., J.E.A.-C., S.P., A.C., F.E., P.B., C.N., S.G.P.); CeSI-Center for Research on Ageing & DNI-Department of Neuroscience and Imaging, University G. d'Annunzio, Chieti, Italy (S.B., L.P., F.P.); Facultad de Ciencias Médicas, Centro de Investigaciones Cardiovasculares, UNLP-CONICET, La Plata, Argentina (V.C.D.G.); Laboratorio de Cardiología Molecular, Insituto de Fisiología, Benemérita Universidad Autónoma de Puebla, Puebla, México (J.E.A.-C.); Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China (N.L.); Division of Cardiology, Department of Medical and Surgical Science, University of "Magna Graecia," Catanzaro, Italy (A.C.); Federico II University of Naples, Cardiology, Naples, Italy (F.E.); INSERM U836, Grenoble Institut des Neurosciences, Equipe Muscle et Pathologies, Grenoble, France (I.M.); Université Joseph Fourier, Grenoble, France (I.M.); Pathology Division, IRCCS Fondazione Salvatore Maugeri, Pavia, Italy (L.V.); Laboratorio de Ecología de la Conducta, Instituto de Fisiología, Benemérita Universidad Autónoma de Puebla, Puebla, México (A.M.); Telethon Institute of Genetics and Medicine, Naples, Italy (A.A.); Medical Genetics, Department of Translational Medicine, "Federico II" University, Naples, Italy (A.A.); and Department of Molecular Medicine, University of Pavia, Pavia, Italy (S.G.P.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.006901DOI Listing
June 2014
81 Reads
12 Citations
14.430 Impact Factor

Supporting shared decision making within the MobiGuide project.

AMIA Annu Symp Proc 2013 16;2013:1175-84. Epub 2013 Nov 16.

University of Pavia, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900138PMC
May 2014
14 Reads
4 Citations

Novel insight into the natural history of short QT syndrome.

J Am Coll Cardiol 2014 Apr 28;63(13):1300-1308. Epub 2013 Nov 28.

Molecular Cardiology, IRCCS Salvatore Maugeri Foundation, Pavia, Italy; Cardiovascular Genetics Program, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York; Department of Molecular Medicine, University of Pavia, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2013.09.078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988978PMC
April 2014
11 Reads
19 Citations
16.503 Impact Factor

Subclinical abnormalities in sarcoplasmic reticulum Ca(2+) release promote eccentric myocardial remodeling and pump failure death in response to pressure overload.

J Am Coll Cardiol 2014 Apr 4;63(15):1569-79. Epub 2013 Dec 4.

Department of Cardiology, Medical University of Graz, Graz, Austria; Ludwig Boltzmann Institute for Translational Heart Failure Research, Graz, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2013.11.010DOI Listing
April 2014
44 Reads
9 Citations
16.503 Impact Factor

The usual suspects in sudden cardiac death of the young: a focus on inherited arrhythmogenic diseases.

Expert Rev Cardiovasc Ther 2014 Apr;12(4):499-519

Molecular Cardiology, IRCCS Salvatore Maugeri Foundation, Pavia, Italy.

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http://dx.doi.org/10.1586/14779072.2014.894884DOI Listing
April 2014
25 Reads
4 Citations

Missense mutations in plakophilin-2 cause sodium current deficit and associate with a Brugada syndrome phenotype.

Circulation 2014 Mar 18;129(10):1092-103. Epub 2013 Dec 18.

Leon H. Charney Division of Cardiology (M.C., X.L., M.Z., E.A.-P., A.P., H.C.G., S.P., M.D.), and Cardiovascular Genetics Program (M.C., S.P.), NYU School of Medicine, New York, NY; Molecular Cardiology, Maugeri Foundation, Pavia, Italy (V.N., C.N., S.P.); Del E. Webb Center for Neuroscience, Aging & Stem Cell Research, Sanford-Burnham Medical Research Institute, La Jolla, CA (C.K., T.T., H.-S.V.C.); Department of Bioscience and Biotechnology, Sejong University, Seoul, Korea (C.K.); Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD (D.P.J.); and Department of Pharmacology, NYU School of Medicine, New York, NY (E.R.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.003077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954430PMC
March 2014
35 Reads
71 Citations
14.430 Impact Factor

Clinical utility gene card for: Catecholaminergic polymorphic ventricular tachycardia (CPVT).

Eur J Hum Genet 2014 Jan 3;22(1). Epub 2013 Apr 3.

1] IRCCS Fondazione Maugeri, Pavia, Italy [2] Cardiovascular Genetics, Leon Charney Division of Cardiology, New York University, New York, NY, USA [3] Department of Molecular Medicine, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1038/ejhg.2013.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865399PMC
January 2014
14 Reads
3 Citations
4.350 Impact Factor

Clinical and research data integration: the i2b2-FSM experience.

AMIA Jt Summits Transl Sci Proc 2013 18;2013:239-40. Epub 2013 Mar 18.

IRCCS Fondazione Salvatore Maugeri, Pavia, Italy;

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December 2013
22 Reads
1 Citation

Heart, brain, and the risk of sudden death.

Authors:
Carlo Napolitano

Heart Rhythm 2013 Jul 12;10(7):999-1000. Epub 2013 Apr 12.

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http://dx.doi.org/10.1016/j.hrthm.2013.04.008DOI Listing
July 2013
4 Reads
5.080 Impact Factor

Abnormal propagation of calcium waves and ultrastructural remodeling in recessive catecholaminergic polymorphic ventricular tachycardia.

Circ Res 2013 Jul 14;113(2):142-52. Epub 2013 May 14.

Leon H. Charney Division of Cardiology, Cardiovascular Genetics Program, New York University School of Medicine, New York, NY, USA.

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.113.30178
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http://dx.doi.org/10.1161/CIRCRESAHA.113.301783DOI Listing
July 2013
33 Reads
18 Citations
11.020 Impact Factor

Decreased RyR2 refractoriness determines myocardial synchronization of aberrant Ca2+ release in a genetic model of arrhythmia.

Proc Natl Acad Sci U S A 2013 Jun 3;110(25):10312-7. Epub 2013 Jun 3.

D. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1073/pnas.1300052110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690898PMC
June 2013
55 Reads
25 Citations
9.810 Impact Factor

The contradictory genetics of atrial fibrillation: the growing gap between knowledge and clinical implications.

Authors:
Carlo Napolitano

J Cardiovasc Electrophysiol 2013 May 1;24(5):570-2. Epub 2013 Feb 1.

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http://dx.doi.org/10.1111/jce.12091DOI Listing
May 2013
2.960 Impact Factor

Bridging the dimensions of research on cardiac ryanodine receptor mutations.

Authors:
Carlo Napolitano

J Cardiovasc Electrophysiol 2013 Feb 9;24(2):219-20. Epub 2012 Nov 9.

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http://dx.doi.org/10.1111/jce.12028DOI Listing
February 2013
4 Reads
1 Citation
2.960 Impact Factor

CARDIO-i2b2: integrating arrhythmogenic disease data in i2b2.

Stud Health Technol Inform 2012 ;180:1126-8

IRCCS Fondazione Salvatore Maugeri, Pavia, Italy.

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January 2013
8 Reads
5 Citations

Induced pluripotent stem cell-derived cardiomyocytes in studies of inherited arrhythmias.

J Clin Invest 2013 Jan 2;123(1):84-91. Epub 2013 Jan 2.

Division of Cardiology and Molecular Cardiology, Maugeri Foundation-University of Pavia, Via Maugeri 10/10°, 27100 Pavia, Italy.

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http://dx.doi.org/10.1172/JCI62838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533271PMC
January 2013
20 Reads
40 Citations
13.215 Impact Factor

Inherited calcium channelopathies in the pathophysiology of arrhythmias.

Nat Rev Cardiol 2012 Oct 26;9(10):561-75. Epub 2012 Jun 26.

Molecular Cardiology, IRCCS Fondazione Salvatore Maugeri, Via Maugeri 10/10a, Pavia 27100, Italy.

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http://dx.doi.org/10.1038/nrcardio.2012.93DOI Listing
October 2012
5 Reads
49 Citations
9.183 Impact Factor

Genetic testing of inherited arrhythmias.

Authors:
Carlo Napolitano

Pediatr Cardiol 2012 Aug 17;33(6):980-7. Epub 2012 Mar 17.

Molecular Cardiology Laboratories, IRCCS Fondazione Salvatore Maugeri, Via Maugeri 10, 27100, Pavia, Italy.

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http://dx.doi.org/10.1007/s00246-012-0287-7DOI Listing
August 2012
10 Reads
3 Citations
1.550 Impact Factor

Genetics of ion-channel disorders.

Curr Opin Cardiol 2012 May;27(3):242-52

Leon H. Charney Division of Cardiology, New York University, New York, New York, USA.

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http://dx.doi.org/10.1097/HCO.0b013e328352429dDOI Listing
May 2012
3 Reads
13 Citations
2.700 Impact Factor

Meandering pathway leading from genotyping to personalized management of long-QT syndrome.

Circulation 2012 Apr 28;125(16):1961-3. Epub 2012 Mar 28.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.112.102293DOI Listing
April 2012
7 Reads
14.430 Impact Factor

Sudden cardiac death and genetic ion channelopathies: long QT, Brugada, short QT, catecholaminergic polymorphic ventricular tachycardia, and idiopathic ventricular fibrillation.

Circulation 2012 Apr;125(16):2027-34

Molecular Cardiology, IRCCS Salvatore Maugeri Foundation, Pavia, Italy.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.111.055947DOI Listing
April 2012
14 Reads
12 Citations
14.430 Impact Factor

Genetics and arrhythmias: diagnostic and prognostic applications.

Rev Esp Cardiol (Engl Ed) 2012 Mar 14;65(3):278-86. Epub 2012 Jan 14.

Medicina Molecolare, IRCCS Fondazione Salvatore Maugeri, Pavía, Italy.

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http://dx.doi.org/10.1016/j.recesp.2011.10.008DOI Listing
March 2012
4 Reads
2 Citations

Flecainide and antiarrhythmic effects in a mouse model of catecholaminergic polymorphic ventricular tachycardia.

Trends Cardiovasc Med 2012 Feb 4;22(2):35-9. Epub 2012 Aug 4.

Cardiovascular Genetic Program, The Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.tcm.2012.06.008DOI Listing
February 2012
16 Reads
5 Citations
2.910 Impact Factor

Risk stratification in Brugada syndrome: results of the PRELUDE (PRogrammed ELectrical stimUlation preDictive valuE) registry.

J Am Coll Cardiol 2012 Jan;59(1):37-45

Cardiologia Molecolare, IRCCS Fondazione Salvatore Maugeri, Via Maugeri 10/10a, Pavia, Italy.

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http://dx.doi.org/10.1016/j.jacc.2011.08.064DOI Listing
January 2012
27 Reads
60 Citations
16.503 Impact Factor

Role of calmodulin kinase in catecholaminergic polymorphic ventricular tachycardia.

Heart Rhythm 2011 Oct 10;8(10):1601-5. Epub 2011 Mar 10.

Molecular Cardiology, IRCCS, Fondazione Salvatore Maugeri, Pavia, Italy.

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http://dx.doi.org/10.1016/j.hrthm.2011.03.012DOI Listing
October 2011
3 Reads
5.080 Impact Factor

Short communication: flecainide exerts an antiarrhythmic effect in a mouse model of catecholaminergic polymorphic ventricular tachycardia by increasing the threshold for triggered activity.

Circ Res 2011 Jul 16;109(3):291-5. Epub 2011 Jun 16.

Cardiovascular Genetics Program, Leon H. Charney Division of Cardiology, New York University School of Medicine, 522 First Ave, New York, NY 10016, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.111.247338DOI Listing
July 2011
8 Reads
30 Citations
11.020 Impact Factor

R engine cell: integrating R into the i2b2 software infrastructure.

J Am Med Inform Assoc 2011 May 24;18(3):314-7. Epub 2011 Jan 24.

IRCCS Fondazione S. Maugeri, Pavia, Italy.

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http://dx.doi.org/10.1136/jamia.2010.007914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078677PMC
May 2011
5 Reads
11 Citations
3.504 Impact Factor

Phenotypical manifestations of mutations in the genes encoding subunits of the cardiac voltage-dependent L-type calcium channel.

Circ Res 2011 Mar;108(5):607-18

Executive Director and Director of Research, Gordon K. Moe Scholar, Masonic Medical Research Laboratory, 2150 Bleecker St, Utica, NY 13501, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.110.224279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056572PMC
March 2011
6 Reads
14 Citations
11.020 Impact Factor

Y1767C, a novel SCN5A mutation, induces a persistent Na+ current and potentiates ranolazine inhibition of Nav1.5 channels.

Am J Physiol Heart Circ Physiol 2011 Jan 12;300(1):H288-99. Epub 2010 Nov 12.

Centre de Recherche, Université Laval Robert-Giffard, Quebec City, Quebec, Canada.

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http://dx.doi.org/10.1152/ajpheart.00539.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774256PMC
January 2011
25 Reads
18 Citations
3.840 Impact Factor

Calmodulin kinase II inhibition prevents arrhythmias in RyR2(R4496C+/-) mice with catecholaminergic polymorphic ventricular tachycardia.

J Mol Cell Cardiol 2011 Jan 23;50(1):214-22. Epub 2010 Oct 23.

Cardiovascular Genetics Program, The Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2010.10.001DOI Listing
January 2011
6 Reads
32 Citations
4.660 Impact Factor

The slow pace of the heart and the objectives of molecular cardiology.

Authors:
Carlo Napolitano

J Cardiovasc Electrophysiol 2010 Dec 30;21(12):1373-4. Epub 2010 Aug 30.

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http://dx.doi.org/10.1111/j.1540-8167.2010.01879.xDOI Listing
December 2010
3 Reads
2.960 Impact Factor

In the RyR2(R4496C) mouse model of CPVT, β-adrenergic stimulation induces Ca waves by increasing SR Ca content and not by decreasing the threshold for Ca waves.

Circ Res 2010 Dec 21;107(12):1483-9. Epub 2010 Oct 21.

Unit of Cardiac Physiology, Manchester Academic Health Sciences Centre, University of Manchester, 46 Grafton St, Manchester M13 9NT, United Kingdom.

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http://dx.doi.org/10.1161/CIRCRESAHA.110.227744DOI Listing
December 2010
9 Reads
36 Citations
11.020 Impact Factor

Genetic testing for inherited cardiac arrhythmias.

Hellenic J Cardiol 2010 Mar-Apr;51(2):92-103

Cardiovascular Genetics Program, Leon H. Charney Division of Cardiology, NYU Langone Medical Center, New York, USA.

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December 2010
4 Reads
1 Citation
0.785 Impact Factor

Na+-dependent SR Ca2+ overload induces arrhythmogenic events in mouse cardiomyocytes with a human CPVT mutation.

Cardiovasc Res 2010 Jul 15;87(1):50-9. Epub 2010 Jan 15.

Division of Cardiology, Medical University of Graz, Auenbruggerplatz 15, Graz A-8036, Austria.

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http://dx.doi.org/10.1093/cvr/cvq007DOI Listing
July 2010
31 Reads
38 Citations
5.940 Impact Factor

Polymorphisms in the NOS1AP gene modulate QT interval duration and risk of arrhythmias in the long QT syndrome.

J Am Coll Cardiol 2010 Jun;55(24):2745-52

Molecular Cardiology Laboratories, IRCCS Salvatore Maugeri Foundation, Pavia, Italy.

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http://dx.doi.org/10.1016/j.jacc.2009.12.065DOI Listing
June 2010
9 Reads
51 Citations
16.503 Impact Factor

Trafficking defects and gating abnormalities of a novel SCN5A mutation question gene-specific therapy in long QT syndrome type 3.

Circ Res 2010 Apr 25;106(8):1374-83. Epub 2010 Mar 25.

Cardiovascular Genetics Program, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.110.218891DOI Listing
April 2010
22 Reads
19 Citations
11.020 Impact Factor

When is genetic testing useful in patients suspected to have inherited cardiac arrhythmias?

Curr Opin Cardiol 2010 Jan;25(1):37-45

Cardiovascular Genetics Program, New York University Langone Medical Center, New York, New York 10016, USA.

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http://dx.doi.org/10.1097/HCO.0b013e3283335901DOI Listing
January 2010
7 Reads
2 Citations
2.700 Impact Factor

The genetics of cardiomyopathy: genotyping and genetic counseling.

Curr Treat Options Cardiovasc Med 2009 Dec;11(6):433-46

New York University Langone Medical Center, Leon H. Carney Division of Cardiology, Smilow Research Building, Room 701, 522 First Avenue, New York, NY 10016, USA.

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December 2009
6 Reads

Catecholaminergic polymorphic ventricular tachycardia: A paradigm to understand mechanisms of arrhythmias associated to impaired Ca(2+) regulation.

Heart Rhythm 2009 Nov 30;6(11):1652-9. Epub 2009 Jun 30.

Cardiovascular Genetics, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1016/j.hrthm.2009.06.033DOI Listing
November 2009
10 Reads
20 Citations
5.080 Impact Factor

Magnetic resonance investigations in Brugada syndrome reveal unexpectedly high rate of structural abnormalities.

Eur Heart J 2009 Sep 26;30(18):2241-8. Epub 2009 Jun 26.

Division of Cardiology, IRCCS Fondazione Salvatore Maugeri, via Maugeri 8, 27100 Pavia, Italy.

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http://dx.doi.org/10.1093/eurheartj/ehp252DOI Listing
September 2009
36 Reads
32 Citations
15.203 Impact Factor

The heritable nature of the electrocardiogram: How far can population genetics go?

Authors:
Carlo Napolitano

Heart Rhythm 2009 May 3;6(5):642-3. Epub 2009 Mar 3.

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http://dx.doi.org/10.1016/j.hrthm.2009.03.007DOI Listing
May 2009
2 Reads
5.080 Impact Factor

Yield of genetic screening in inherited cardiac channelopathies: how to prioritize access to genetic testing.

Circ Arrhythm Electrophysiol 2009 Feb 10;2(1):6-15. Epub 2009 Feb 10.

Molecular Cardiology, IRCCS Fondazione Salvatore Maugeri, Pavia, Italy.

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http://dx.doi.org/10.1161/CIRCEP.108.782888DOI Listing
February 2009
7 Reads
13 Citations

Increased Ca2+ sensitivity of the ryanodine receptor mutant RyR2R4496C underlies catecholaminergic polymorphic ventricular tachycardia.

Circ Res 2009 Jan 18;104(2):201-9, 12p following 209. Epub 2008 Dec 18.

Institut National de la Santé et de la Recherche Médicale, U637, Université de Montpellier, Montpellier, France.

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http://dx.doi.org/10.1161/CIRCRESAHA.108.177493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796688PMC
January 2009
85 Reads
50 Citations
11.020 Impact Factor

Therapeutic strategies for long-QT syndrome: does the molecular substrate matter?

Circ Arrhythm Electrophysiol 2008 Oct;1(4):290-7

Molecular Cardiology Fondazione Salvatore Maugeri, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1161/CIRCEP.108.795617DOI Listing
October 2008
11 Reads
15 Citations

Risk of death in the long QT syndrome when a sibling has died.

Heart Rhythm 2008 Jun 4;5(6):831-6. Epub 2008 Mar 4.

Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1016/j.hrthm.2008.02.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486317PMC
June 2008
91 Reads
6 Citations
5.080 Impact Factor

Long-QT syndrome after age 40.

Circulation 2008 Apr 21;117(17):2192-201. Epub 2008 Apr 21.

Cardiology Division of the Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.729368DOI Listing
April 2008
10 Reads
22 Citations
14.430 Impact Factor

Arrhythmogenic mechanisms in a mouse model of catecholaminergic polymorphic ventricular tachycardia.

Circ Res 2007 Nov 13;101(10):1039-48. Epub 2007 Sep 13.

Department of Pharmacology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.107.148064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515360PMC
November 2007
15 Reads
89 Citations
11.020 Impact Factor

Gating properties of SCN5A mutations and the response to mexiletine in long-QT syndrome type 3 patients.

Circulation 2007 Sep 13;116(10):1137-44. Epub 2007 Aug 13.

Molecular Cardiology, Fondazione Salvatore Maugeri, Via Maugeri 10/10A, 27100 Pavia, Italy.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.707877DOI Listing
September 2007
9 Reads
42 Citations
14.430 Impact Factor

Molecular and electrophysiological bases of catecholaminergic polymorphic ventricular tachycardia.

J Cardiovasc Electrophysiol 2007 Jul;18(7):791-7

Division of Cardiology, Department of Medicine, London Health Science Centre, London, Canada.

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http://dx.doi.org/10.1111/j.1540-8167.2007.00766.xDOI Listing
July 2007
47 Reads
27 Citations
2.960 Impact Factor

Diagnosis and treatment of catecholaminergic polymorphic ventricular tachycardia.

Heart Rhythm 2007 May 7;4(5):675-8. Epub 2007 Jan 7.

Molecular Cardiology, IRCCS Fondazione Maugeri, Pavia, Italy.

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http://dx.doi.org/10.1016/j.hrthm.2006.12.048DOI Listing
May 2007
3 Reads
17 Citations
5.080 Impact Factor

Long QT syndrome and pregnancy.

J Am Coll Cardiol 2007 Mar 27;49(10):1092-8. Epub 2007 Feb 27.

Cardiology Division of the Department of Medicine, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1016/j.jacc.2006.09.054DOI Listing
March 2007
30 Reads
41 Citations
16.503 Impact Factor

In silico assessment of Y1795C and Y1795H SCN5A mutations: implication for inherited arrhythmogenic syndromes.

Am J Physiol Heart Circ Physiol 2007 Jan 15;292(1):H56-65. Epub 2006 Sep 15.

DEIS, Viale Risorgimento, 2, I-40136, Bologna, Italy.

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http://dx.doi.org/10.1152/ajpheart.00270.2006DOI Listing
January 2007
78 Reads
5 Citations
3.840 Impact Factor

Just another Brugada syndrome mutation?

Authors:
Carlo Napolitano

Heart Rhythm 2007 Jan 17;4(1):54-5. Epub 2006 Nov 17.

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http://dx.doi.org/10.1016/j.hrthm.2006.11.006DOI Listing
January 2007
9 Reads
5.080 Impact Factor

Long QT syndrome in adults.

J Am Coll Cardiol 2007 Jan 4;49(3):329-37. Epub 2007 Jan 4.

Cardiology Unit of the Department of Medicine, University of Rochester Medical Center, Rochester, New York 14642-8653, USA.

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http://dx.doi.org/10.1016/j.jacc.2006.08.057DOI Listing
January 2007
6 Reads
73 Citations
16.503 Impact Factor

Female predominance and transmission distortion in the long-QT syndrome.

N Engl J Med 2006 Dec;355(26):2744-51

INSERM, Institut de Myologie, Université Pierre et Marie Curie, Institut Fédératif de Recherche 14 and Groupe Hospitalier Pitié-Salpêtrière, Paris, France.

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http://dx.doi.org/10.1056/NEJMoa042786DOI Listing
December 2006
15 Reads
11 Citations
55.873 Impact Factor

Brugada syndrome.

Orphanet J Rare Dis 2006 Sep 14;1:35. Epub 2006 Sep 14.

Molecular Cardiology Laboratories, IRCCS, Fondazione Salvatore Maugeri, Via Ferrata 8, 27100 Pavia, Italy.

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http://dx.doi.org/10.1186/1750-1172-1-35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592481PMC
September 2006
7 Reads
7 Citations
3.360 Impact Factor

Molecular underpinning of "good luck".

Circulation 2006 Aug;114(5):360-2

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.643866DOI Listing
August 2006
5 Reads
14.430 Impact Factor

Arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia: insights from a RyR2 R4496C knock-in mouse model.

Circ Res 2006 Aug 6;99(3):292-8. Epub 2006 Jul 6.

Molecular Cardiology, IRCCS Fondazione Salvatore Maugeri, Pavia, Italy.

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http://dx.doi.org/10.1161/01.RES.0000235869.50747.e1DOI Listing
August 2006
13 Reads
83 Citations
11.020 Impact Factor

Long QT syndrome and short QT syndrome: how to make correct diagnosis and what about eligibility for sports activity.

J Cardiovasc Med (Hagerstown) 2006 Apr;7(4):250-6

Molecular Cardiology, IRCCS Fondazione Salvatore Maugeri, Pavia, Italy.

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http://dx.doi.org/10.2459/01.JCM.0000219317.12504.5fDOI Listing
April 2006
25 Reads
3 Citations
1.410 Impact Factor

Gene-specific therapy for inherited arrhythmogenic diseases.

Pharmacol Ther 2006 Apr 15;110(1):1-13. Epub 2005 Sep 15.

Molecular Cardiology, IRCCS Fondazione Maugeri, Pavia, Italy.

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http://dx.doi.org/10.1016/j.pharmthera.2005.08.003DOI Listing
April 2006
1 Read
5 Citations
9.723 Impact Factor

Computer simulation of wild-type and mutant human cardiac Na+ current.

Med Biol Eng Comput 2006 Mar;44(1-2):35-44

Cellular and Molecular Engineering Laboratory, DEIS, University of Bologna, via Venezia 52, 47023 Cesena (FC), Italy.

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http://dx.doi.org/10.1007/s11517-005-0017-xDOI Listing
March 2006
8 Reads
4 Citations
1.500 Impact Factor

Role of genetic analyses in cardiology: part I: mendelian diseases: cardiac channelopathies.

Circulation 2006 Feb;113(8):1130-5

Molecular Cardiology, Maugeri Foundation, IRCCS, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.105.563205DOI Listing
February 2006
9 Reads
9 Citations
14.430 Impact Factor

Cardiac histological substrate in patients with clinical phenotype of Brugada syndrome.

Circulation 2005 Dec;112(24):3680-7

Heart and Great Vessels Department, Attilio Reale, La Sapienza University, Rome, Italy.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.105.520999DOI Listing
December 2005
10 Reads
44 Citations
14.430 Impact Factor

Genetic testing in the long QT syndrome: development and validation of an efficient approach to genotyping in clinical practice.

JAMA 2005 Dec;294(23):2975-80

Molecular Cardiology, IRCCS Fondazione S. Maugeri Foundation, Pavia, Italy.

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http://dx.doi.org/10.1001/jama.294.23.2975DOI Listing
December 2005
10 Reads
104 Citations
35.290 Impact Factor

Intracellular calcium handling dysfunction and arrhythmogenesis: a new challenge for the electrophysiologist.

Circ Res 2005 Nov;97(11):1077-9

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http://dx.doi.org/10.1161/01.RES.0000194556.41865.e2DOI Listing
November 2005
5 Reads
9 Citations
11.020 Impact Factor

Cardiac and skeletal muscle disorders caused by mutations in the intracellular Ca2+ release channels.

J Clin Invest 2005 Aug;115(8):2033-8

Molecular Cardiology, Istituto di Ricovero e Cura a Carattere Scientifico Fondazione Maugeri, Pavia, Italy.

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http://dx.doi.org/10.1172/JCI25664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180555PMC
August 2005
8 Reads
22 Citations
13.215 Impact Factor

Should patients with an asymptomatic Brugada electrocardiogram undergo pharmacological and electrophysiological testing?

Circulation 2005 Jul;112(2):279-92; discussion 279-92

Department of Cardiology, University of Pavia, Pavia, Italy.

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July 2005
14 Reads
5 Citations
14.430 Impact Factor

Bidirectional ventricular tachycardia and fibrillation elicited in a knock-in mouse model carrier of a mutation in the cardiac ryanodine receptor.

Circ Res 2005 May 12;96(10):e77-82. Epub 2005 May 12.

Molecular Cardiology, IRCCS Fondazione S. Maugeri, Pavia, Italy.

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http://dx.doi.org/10.1161/01.RES.0000169067.51055.72DOI Listing
May 2005
14 Reads
86 Citations
11.020 Impact Factor

Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes.

Proc Natl Acad Sci U S A 2004 Dec 3;101(50):17533-8. Epub 2004 Dec 3.

Howard Hughes Medical Institute and Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1073/pnas.0403711101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC536011PMC
December 2004
14 Reads
126 Citations
9.810 Impact Factor

Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.

Cell 2004 Oct;119(1):19-31

Department of Cardiology, Children's Hospital, Harvard Medical School and Howard Hughes Medical Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.cell.2004.09.011DOI Listing
October 2004
22 Reads
396 Citations
32.242 Impact Factor

Association of long QT syndrome loci and cardiac events among patients treated with beta-blockers.

JAMA 2004 Sep;292(11):1341-4

Molecular Cardiology, IRCCS Fondazione Maugeri, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1001/jama.292.11.1341DOI Listing
September 2004
7 Reads
83 Citations
35.290 Impact Factor

[Evaluation of BLS-D training in lay people].

Ital Heart J Suppl 2004 Jul;5(7):527-33

Cattedra di Cardiologia, Università degli Studi Federico II, Napoli.

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July 2004
5 Reads

Genetics of cardiac arrhythmias and sudden cardiac death.

Ann N Y Acad Sci 2004 May;1015:96-110

Molecular Cardiology, IRCCS Salvatore Maugeri Foundation, and University of Pavia, Italy.

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http://dx.doi.org/10.1196/annals.1302.008DOI Listing
May 2004
6 Reads
13 Citations
4.313 Impact Factor

Top co-authors

Silvia G Priori
Silvia G Priori

University of Pavia

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Raffaella Bloise
Raffaella Bloise

University of Pavia

13
Nian Liu
Nian Liu

Stanford University

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Peter J Schwartz
Peter J Schwartz

Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics

12
Li Zhang
Li Zhang

Dongfang Hospital Affiliated to Beijing University of Chinese Medicine

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Jesaia Benhorin
Jesaia Benhorin

Tel Aviv Medical Center

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Elizabeth S Kaufman
Elizabeth S Kaufman

University of Rochester Medical Center

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Michael J Ackerman
Michael J Ackerman

Mayo Clinic

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Jennifer L Robinson
Jennifer L Robinson

University of Rochester Medical Center

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Arthur J Moss
Arthur J Moss

University of Rochester Medical Center

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