Carla J Greenbaum

Carla J Greenbaum

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Carla J Greenbaum

Publications by authors named "Carla J Greenbaum"

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High Concentration of Medium-Sized HDL Particles and Enrichment in HDL Paraoxonase 1 Associate With Protection From Vascular Complications in People With Long-standing Type 1 Diabetes.

Diabetes Care 2020 Jan 9;43(1):178-186. Epub 2019 Oct 9.

Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington Medicine Diabetes Institute, University of Washington School of Medicine, Seattle, WA

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http://dx.doi.org/10.2337/dc19-0772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925582PMC
January 2020

Hyaluronan deposition in islets may precede and direct the location of islet immune-cell infiltrates.

Diabetologia 2020 Jan 6. Epub 2020 Jan 6.

Diabetes Research Program and Clinical Research Center, Benaroya Research Institute at Virginia Mason, Seattle, WA, USA.

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http://dx.doi.org/10.1007/s00125-019-05066-7DOI Listing
January 2020

Abnormalities in proinsulin processing in islets from individuals with longstanding T1D.

Transl Res 2019 Nov 9;213:90-99. Epub 2019 Aug 9.

Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana; The Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana; Roudebush VA Medical Center, Indianapolis, Indiana. Electronic address:

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http://dx.doi.org/10.1016/j.trsl.2019.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783367PMC
November 2019

An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes.

N Engl J Med 2019 08 9;381(7):603-613. Epub 2019 Jun 9.

From the Departments of Immunobiology and Internal Medicine, Yale University, New Haven, CT (K.C.H.); the Departments of Epidemiology and Pediatrics, University of South Florida, Tampa (B.N.B., J.P.K., H.R.), the Department of Medicine, University of Miami, Miami (J.B.M., J.S.S.), and the Department of Pediatrics, University of Florida, Gainesville (D.S.) - all in Florida; Benaroya Research Institute, Seattle (S.A.L., M.J.D., P.S.L., C.J.G.); the Diabetes Center, University of California at San Francisco, San Francisco (J.A.B., S.E.G.); the Department of Pediatrics, Indiana University, Indianapolis (L.A.D.); the Barbara Davis Diabetes Center, University of Colorado, Anschultz (P.A.G.); Children's Mercy Hospital, Kansas City, MO (W.M.); the Department of Pediatrics, University of Minnesota, Minneapolis (A.M.); the Department of Pediatrics and Cell and Developmental Biology, Vanderbilt University, Nashville (W.E.R.); the Department of Pediatrics, University of Iowa, Iowa City (E.T.); the Hospital for Sick Children, University of Toronto, Toronto (D.K.W.); and Forschergruppe Diabetes, Technical University Munich, at Klinikum rechts der Isar, Munich, Germany (A.-G.Z.).

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http://dx.doi.org/10.1056/NEJMoa1902226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776880PMC
August 2019

Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes.

Genes Immun 2019 04 21;20(4):293-307. Epub 2018 Jun 21.

Systems Immunology Program, Benaroya Research Institute at Virginia Mason, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41435-018-0032-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477779PMC
April 2019

Genetics Coming of Age in Type 1 Diabetes.

Diabetes Care 2019 02;42(2):189-191

Diabetes Program, Benaroya Research Institute, Seattle, WA

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http://dx.doi.org/10.2337/dci18-0039DOI Listing
February 2019

ISPAD Clinical Practice Consensus Guidelines 2018: Stages of type 1 diabetes in children and adolescents.

Pediatr Diabetes 2018 10;19 Suppl 27:20-27

Department of Diabetes and Endocrinology, The Children's Hospital at Westmead, Sydney, Australia.

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http://dx.doi.org/10.1111/pedi.12734DOI Listing
October 2018

Assessment of β Cell Mass and Function by AIRmax and Intravenous Glucose in High-Risk Subjects for Type 1 Diabetes.

J Clin Endocrinol Metab 2017 12;102(12):4428-4434

Diabetes Clinical Research Program, Benaroya Research Institute at Virginia Mason.

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http://dx.doi.org/10.1210/jc.2017-01713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718693PMC
December 2017

Stacking the Deck: Studies of Patients with Multiple Autoimmune Diseases Propelled Our Understanding of Type 1 Diabetes as an Autoimmune Disease.

J Immunol 2017 11;199(9):3011-3013

Diabetes Research Program, Benaroya Research Institute at Virginia Mason, Seattle, WA 98101

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http://dx.doi.org/10.4049/jimmunol.1701299DOI Listing
November 2017

Measurement of Pro-Islet Amyloid Polypeptide (1-48) in Diabetes and Islet Transplants.

J Clin Endocrinol Metab 2017 07;102(7):2595-2603

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada.

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http://dx.doi.org/10.1210/jc.2016-2773DOI Listing
July 2017

Fall in C-Peptide During First 4 Years From Diagnosis of Type 1 Diabetes: Variable Relation to Age, HbA1c, and Insulin Dose.

Diabetes Care 2016 Oct 15;39(10):1664-70. Epub 2016 Jul 15.

Diabetes Clinical Research Program, Benaroya Research Institute at Virginia Mason, Seattle, WA.

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http://dx.doi.org/10.2337/dc16-0360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033079PMC
October 2016

Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset.

Eur J Immunol 2016 Apr 21;46(4):1030-46. Epub 2016 Jan 21.

The Max McGee National Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, and Department of Pediatrics at the Medical College of Wisconsin, Milwaukee, WI, USA.

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http://dx.doi.org/10.1002/eji.201546005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828314PMC
April 2016

Heterogeneity in recent-onset type 1 diabetes - a clinical trial perspective.

Diabetes Metab Res Rev 2015 Sep 23;31(6):588-94. Epub 2015 Apr 23.

Benaroya Research Institute, Seattle, WA, USA.

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http://dx.doi.org/10.1002/dmrr.2643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815427PMC
September 2015

Disease modifying therapies in type 1 diabetes: Where have we been, and where are we going?

Pharmacol Res 2015 Aug 11;98:3-8. Epub 2015 Mar 11.

Diabetes Clinical Research Program, Benaroya Research Institute, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.phrs.2015.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469522PMC
August 2015

The Effect of DPT-1 Intravenous Insulin Infusion and Daily Subcutaneous Insulin on Endogenous Insulin Secretion and Postprandial Glucose Tolerance.

Diabetes Care 2015 May 26;38(5):891-6. Epub 2015 Feb 26.

Department of Medicine, Division of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle, WA Department of Veterans Affairs, Puget Sound Health Care System, Seattle, WA.

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http://dx.doi.org/10.2337/dc14-1825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407749PMC
May 2015

The development and utility of a novel scale that quantifies the glycemic progression toward type 1 diabetes over 6 months.

Diabetes Care 2015 May 10;38(5):940-2. Epub 2015 Mar 10.

VA Puget Sound Health Care System; Division of Endocrinology, Metabolism, and Nutrition, University of Washington, Seattle, WA.

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http://dx.doi.org/10.2337/dc14-2787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407750PMC
May 2015

A new approach for diagnosing type 1 diabetes in autoantibody-positive individuals based on prediction and natural history.

Diabetes Care 2015 Feb 17;38(2):271-6. Epub 2014 Dec 17.

VA Puget Sound Health Care System, Division of Endocrinology, Metabolism, and Nutrition, University of Washington, Seattle, WA.

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http://dx.doi.org/10.2337/dc14-1813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302258PMC
February 2015

Avidity-dependent programming of autoreactive T cells in T1D.

PLoS One 2014 20;9(5):e98074. Epub 2014 May 20.

Benaroya Research Institute at Virginia Mason, Seattle, Washington, United States of America; University of Washington School of Medicine, Seattle, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098074PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028311PMC
January 2015

Molecular signatures differentiate immune states in type 1 diabetic families.

Diabetes 2014 Nov 23;63(11):3960-73. Epub 2014 Apr 23.

The Max McGee National Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, and Department of Pediatrics at the Medical College of Wisconsin, Milwaukee, WI

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http://dx.doi.org/10.2337/db14-0214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207392PMC
November 2014

Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes.

Proc Natl Acad Sci U S A 2014 Oct 29;111(41):14840-5. Epub 2014 Sep 29.

Benaroya Research Institute, Seattle, WA 98101; Department of Medicine, University of Washington, Seattle, WA 98195

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http://dx.doi.org/10.1073/pnas.1416864111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205657PMC
October 2014

Low HERV-K(C4) copy number is associated with type 1 diabetes.

Diabetes 2014 May 15;63(5):1789-95. Epub 2014 Jan 15.

Systems Immunology, Benaroya Research Institute, Seattle, WA.

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http://dx.doi.org/10.2337/db13-1382DOI Listing
May 2014

Residual C-peptide in type 1 diabetes: what do we really know?

Pediatr Diabetes 2014 Mar;15(2):84-90

Diabetes Clinical Research Program, Benaroya Research Institute, Seattle, WA, 98101, USA.

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http://dx.doi.org/10.1111/pedi.12135DOI Listing
March 2014

IL-2 therapy in type 1 diabetes: "Trials" and tribulations.

Clin Immunol 2013 Dec 22;149(3):324-31. Epub 2013 Feb 22.

Translational Immunology, Benaroya Research Institute, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.clim.2013.02.005DOI Listing
December 2013

Dead or alive?

Diabetes Care 2012 Mar;35(3):459-60

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http://dx.doi.org/10.2337/dc11-2441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322728PMC
March 2012

Making progress: preserving beta cells in type 1 diabetes.

Ann N Y Acad Sci 2011 Dec;1243:119-34

Naomi Berrie Diabetes Center, Columbia University, College of Physicians and Surgeons, New York, New York, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2011.06321.xDOI Listing
December 2011

Metabolic tests to determine risk for type 1 diabetes in clinical trials.

Diabetes Metab Res Rev 2011 Sep;27(6):584-9

Diabetes Program, Benaroya Research Institute, Seattle, WA 98101, USA.

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http://dx.doi.org/10.1002/dmrr.1205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162108PMC
September 2011

Omental roll-up: a technique for islet engraftment in a large animal model.

J Surg Res 2010 Jun 13;161(1):134-8. Epub 2008 Dec 13.

Division of Renal and Pancreas Transplantation, Virginia Mason Medical Center, Seattle, Washington 98101, USA.

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http://dx.doi.org/10.1016/j.jss.2008.11.842DOI Listing
June 2010

Preservation of beta-cell function in autoantibody-positive youth with diabetes.

Diabetes Care 2009 Oct 8;32(10):1839-44. Epub 2009 Jul 8.

Diabetes Research Program, Benaroya Research Institute, Seattle,Washington, USA.

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http://dx.doi.org/10.2337/dc08-2326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752937PMC
October 2009

Changes in autoreactive T cell avidity during type 1 diabetes development.

Clin Immunol 2009 Sep 23;132(3):312-20. Epub 2009 May 23.

Benaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S152166160900658
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http://dx.doi.org/10.1016/j.clim.2009.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720757PMC
September 2009

Type 1 diabetes mellitus: primary, secondary, and tertiary prevention.

Mt Sinai J Med 2008 Aug;75(4):385-97

Diabetes Program, Benaroya Research Institute, Seattle, WA, USA.

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http://dx.doi.org/10.1002/msj.20054DOI Listing
August 2008

Standardization of C-peptide measurements.

Clin Chem 2008 Jun 17;54(6):1023-6. Epub 2008 Apr 17.

Diabetes Diagnostic Laboratory, Department of Pathology & Anatomical Sciences, University of Missouri School of Medicine, Columbia, MO 65212, USA.

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http://dx.doi.org/10.1373/clinchem.2007.101287DOI Listing
June 2008

Use of oral glucose minimal model-derived index of insulin sensitivity in subjects with early type 1 diabetes mellitus.

Metabolism 2008 Apr;57(4):445-7

Department of Bioengineering, Resource Facility for Population Kinetics, University of Washington, PO Box 355061, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1016/j.metabol.2007.10.001DOI Listing
April 2008

A risk score for type 1 diabetes derived from autoantibody-positive participants in the diabetes prevention trial-type 1.

Diabetes Care 2008 Mar 13;31(3):528-33. Epub 2007 Nov 13.

Division of Endocrinology, University of Miami, P.O. Box 016960 (D110), Miami, FL 33101, USA.

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http://dx.doi.org/10.2337/dc07-1459DOI Listing
March 2008

Editorial: The role of glucagon in postprandial hyperglycemia--the jury's still out.

J Clin Endocrinol Metab 2007 Aug;92(8):2879-81

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http://dx.doi.org/10.1210/jc.2007-1312DOI Listing
August 2007