Carla F Bento

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Carla F Bento

Publications by authors named "Carla F Bento"

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15Publications

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The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Mediated by WIPI2 Recognition of PI3P-RAB11A.

Dev Cell 2018 04;45(1):114-131.e8

Department of Medical Genetics, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK; Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK; UK Dementia Research Institute, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK. Electronic address:

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April 2018

Polyglutamine tracts regulate autophagy.

Autophagy 2017 Sep 19;13(9):1613-1614. Epub 2017 Jul 19.

a Department of Medical Genetics, Cambridge Institute for Medical Research (CIMR) , University of Cambridge , Cambridge , UK.

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September 2017

Polyglutamine tracts regulate beclin 1-dependent autophagy.

Nature 2017 05 26;545(7652):108-111. Epub 2017 Apr 26.

Department of Medical Genetics, Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge, UK.

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May 2017

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.

Neuron 2017 Mar;93(5):1015-1034

Department of Medical Genetics, Cambridge Institute for Medical Research, Cambridge Biomedical Campus, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK. Electronic address:

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March 2017

Mammalian Autophagy: How Does It Work?

Annu Rev Biochem 2016 Jun 8;85:685-713. Epub 2016 Feb 8.

Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Cambridge CB2 0XY, United Kingdom; email:

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June 2016

The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway.

Nat Commun 2016 Jun 9;7:11803. Epub 2016 Jun 9.

Department of Medical Genetics, Cambridge Institute for Medical Research (CIMR), Wellcome/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.

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June 2016

Therapeutic targeting of autophagy in neurodegenerative and infectious diseases.

J Exp Med 2015 Jun 22;212(7):979-90. Epub 2015 Jun 22.

Department of Molecular Genetics and Microbiology and Department of Neurology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131 Department of Molecular Genetics and Microbiology and Department of Neurology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131

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June 2015

Autophagy in the fight against tuberculosis.

DNA Cell Biol 2015 Apr 21;34(4):228-42. Epub 2015 Jan 21.

1 Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge , Cambridge, United Kingdom .

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April 2015

Atorvastatin-mediated protection of the retina in a model of diabetes with hyperlipidemia.

Can J Physiol Pharmacol 2014 Dec 22;92(12):1037-43. Epub 2014 Oct 22.

a Centre of Opththalmology and Vision Sciences - Institute for Biomedical Imaging and Life Sciences (IBILI), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.

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December 2014

PICALM modulates autophagy activity and tau accumulation.

Nat Commun 2014 Sep 22;5:4998. Epub 2014 Sep 22.

Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.

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September 2014

IGF-1 receptor antagonism inhibits autophagy.

Hum Mol Genet 2013 Nov 25;22(22):4528-44. Epub 2013 Jun 25.

Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Wellcome/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

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November 2013

Diverse autophagosome membrane sources coalesce in recycling endosomes.

Cell 2013 Sep;154(6):1285-99

Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.

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September 2013

The role of membrane-trafficking small GTPases in the regulation of autophagy.

J Cell Sci 2013 Mar;126(Pt 5):1059-69

Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.

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March 2013

Regulation of the expression of interleukin-8 induced by 25-hydroxycholesterol in retinal pigment epithelium cells.

Acta Ophthalmol 2012 Jun 7;90(4):e255-63. Epub 2012 Feb 7.

Centre of Ophthalmology and Vision Sciences (COCV), IBILI, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.

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June 2012

Diabetes mellitus: new challenges and innovative therapies.

EPMA J 2010 Mar 13;1(1):138-63. Epub 2010 Mar 13.

Institute of Physiology, Faculty of Medicine, University of Coimbra, Subunit 1, polo 3, Azinhaga de Santa Comba, Celas, 3000-354 Coimbra, Portugal ; IBILI, University of Coimbra, Coimbra, Portugal.

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March 2010