Publications by authors named "Carl Ware"

100Publications

Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues.

Immunity 2020 Nov;53(5):1015-1032.e8

Laboratory of Innate Immunity, Department of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany; Berlin Institute of Health (BIH), Anna-Louisa-Karsch Strasse 2, 10117 Berlin, Germany; Mucosal and Developmental Immunology, Deutsches Rheuma-Forschungszentrum (DRFZ), an institute of the Leibniz Association, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.10.012DOI Listing
November 2020

Contactin-1 Is Required for Peripheral Innervation and Immune Homeostasis Within the Intestinal Mucosa.

Front Immunol 2020 26;11:1268. Epub 2020 Jun 26.

Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.

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http://dx.doi.org/10.3389/fimmu.2020.01268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333639PMC
June 2020

LIGHT/TNFSF14 regulates estrogen deficiency-induced bone loss.

J Pathol 2020 04 25;250(4):440-451. Epub 2020 Feb 25.

Department of Basic and Medical Sciences, Neurosciences and Sense Organs, Section of Human Anatomy and Histology, University of Bari, Bari, Italy.

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http://dx.doi.org/10.1002/path.5385DOI Listing
April 2020

Cutting Edge: The RNA-Binding Protein Ewing Sarcoma Is a Novel Modulator of Lymphotoxin β Receptor Signaling.

J Immunol 2020 03 22;204(5):1085-1090. Epub 2020 Jan 22.

Laboratory of Molecular Immunology, Infectious and Inflammatory Diseases Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037;

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http://dx.doi.org/10.4049/jimmunol.1901260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033016PMC
March 2020

Co-expression Networks Identify DHX15 RNA Helicase as a B Cell Regulatory Factor.

Front Immunol 2019 10;10:2903. Epub 2019 Dec 10.

Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.

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http://dx.doi.org/10.3389/fimmu.2019.02903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915936PMC
November 2020

The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis.

Immunity 2019 08 13;51(2):310-323.e7. Epub 2019 Jun 13.

Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.05.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703922PMC
August 2019

Reply.

Hepatology 2019 09;70(3):1074-1075

Department of Molecular Medicine II, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1002/hep.30600DOI Listing
September 2019

A herpesvirus entry mediator mutein with selective agonist action for the inhibitory receptor B and T lymphocyte attenuator.

J Biol Chem 2017 12 23;292(51):21060-21070. Epub 2017 Oct 23.

From the Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California 92037,

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http://dx.doi.org/10.1074/jbc.M117.813295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743079PMC
December 2017

Treg Depletion Licenses T Cell-Driven HEV Neogenesis and Promotes Tumor Destruction.

Cancer Immunol Res 2017 11 25;5(11):1005-1015. Epub 2017 Sep 25.

Division of Infection and Immunity, School of Medicine, SIURI, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1158/2326-6066.CIR-17-0131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668144PMC
November 2017

HVEM Imprints Memory Potential on Effector CD8 T Cells Required for Protective Mucosal Immunity.

J Immunol 2017 10 1;199(8):2968-2975. Epub 2017 Sep 1.

Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL 32603;

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http://dx.doi.org/10.4049/jimmunol.1700959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783181PMC
October 2017

The NF-κB subunit RelB controls p100 processing by competing with the kinases NIK and IKK1 for binding to p100.

Sci Signal 2016 09 27;9(447):ra96. Epub 2016 Sep 27.

Department of Chemistry and Biochemistry, University of California San Diego, San Diego, CA 92093, USA.

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http://dx.doi.org/10.1126/scisignal.aad9413DOI Listing
September 2016

Lymphotoxin β Receptor Controls T Cell Progenitor Entry to the Thymus.

J Immunol 2016 10 22;197(7):2665-72. Epub 2016 Aug 22.

Medical Research Council Centre for Immune Regulation, Institute for Immunology and Immunotherapy, University of Birmingham, Birmingham B15 2TT, United Kingdom;

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http://dx.doi.org/10.4049/jimmunol.1601189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026032PMC
October 2016

Deletion of P2Y2 receptor reveals a role for lymphotoxin-α in fatty streak formation.

Vascul Pharmacol 2016 10 26;85:11-20. Epub 2016 Jun 26.

Department of Cellular & Integrative Physiology, Indiana University School of Medicine, 635 Barnhill Drive MS 332, Indianapolis, IN 46202, United States. Electronic address:

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http://dx.doi.org/10.1016/j.vph.2016.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453728PMC
October 2016

The TNF Receptor Superfamily in Co-stimulating and Co-inhibitory Responses.

Immunity 2016 05;44(5):1005-19

Infectious and Inflammatory Diseases Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882112PMC
May 2016

Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation.

Nature 2016 Jan 20;529(7587):546-50. Epub 2016 Jan 20.

NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nature16511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856479PMC
January 2016

Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection.

J Virol 2015 May 11;89(9):4748-59. Epub 2015 Feb 11.

Campell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, University Health Network (UHN), Toronto, Ontario, Canada Department of Gastroenterology, Hepatology and Infectious Diseases, University of Düsseldorf, Düsseldorf, Germany Department of Molecular Medicine II, Düsseldorf, Germany

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http://dx.doi.org/10.1128/JVI.02976-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403498PMC
May 2015

Commensal microbiota influence systemic autoimmune responses.

EMBO J 2015 Feb 19;34(4):466-74. Epub 2015 Jan 19.

Laboratory for Molecular Immunology and Inflammation, Department of Rheumatology, Ghent University Hospital, Ghent, Belgium VIB Inflammation Research Center Ghent University, Ghent, Belgium

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http://dx.doi.org/10.15252/embj.201489966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331001PMC
February 2015

NLRs: Sentinels of innate immunity or cancer culprits?

Oncoscience 2014 26;1(5):308-9. Epub 2014 May 26.

Sanford-Burnham Medical Research Institute, La Jolla, CA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278305PMC
http://dx.doi.org/10.18632/oncoscience.44DOI Listing
January 2015

Mixing Signals: Molecular Turn Ons and Turn Offs for Innate γδ T-Cells.

Front Immunol 2014 18;5:654. Epub 2014 Dec 18.

Infectious and Inflammatory Disease Center, Sanford-Burnham Medical Research Institute , La Jolla, CA , USA.

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http://dx.doi.org/10.3389/fimmu.2014.00654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270187PMC
January 2015

Tumor necrosis factor superfamily in innate immunity and inflammation.

Cold Spring Harb Perspect Biol 2014 Dec 18;7(4):a016279. Epub 2014 Dec 18.

Laboratory of Molecular Immunology, Infectious and Inflammatory Disease Center, Sanford Burnham Medical Research Institute, La Jolla, California 92037.

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http://dx.doi.org/10.1101/cshperspect.a016279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382740PMC
December 2014

The thymic microenvironment differentially regulates development and trafficking of invariant NKT cell sublineages.

J Immunol 2014 Dec 7;193(12):5960-72. Epub 2014 Nov 7.

Department of Rheumatology, Laboratory for Molecular Immunology and Inflammation, Ghent University Hospital, Ghent B-9000, Belgium;

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http://dx.doi.org/10.4049/jimmunol.1401601DOI Listing
December 2014

p100/IκBδ sequesters and inhibits NF-κB through kappaBsome formation.

Proc Natl Acad Sci U S A 2014 Nov 27;111(45):15946-51. Epub 2014 Oct 27.

Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093;

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http://dx.doi.org/10.1073/pnas.1408552111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234596PMC
November 2014

Extracellular adenosine regulates colitis through effects on lymphoid and nonlymphoid cells.

Am J Physiol Gastrointest Liver Physiol 2014 Aug 29;307(3):G338-46. Epub 2014 May 29.

Center for Veterinary Sciences and Comparative Medicine, University of California, San Diego, La Jolla, California; Division of Comparative Pathology and Medicine, Department of Pathology, University of California, San Diego, La Jolla, California;

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http://dx.doi.org/10.1152/ajpgi.00404.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121634PMC
August 2014

The Lymphotoxin Network: orchestrating a type I interferon response to optimize adaptive immunity.

Cytokine Growth Factor Rev 2014 Apr 12;25(2):139-45. Epub 2014 Mar 12.

Infectious and Inflammatory Disease Center, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cytogfr.2014.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081445PMC
April 2014

The inhibitory receptor BTLA controls γδ T cell homeostasis and inflammatory responses.

Immunity 2013 Dec 5;39(6):1082-1094. Epub 2013 Dec 5.

Infectious and Inflammatory Diseases Center, Sanford|Burnham Medical Research Institute, 10901 N. Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.immuni.2013.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909738PMC
December 2013

BTLA interaction with HVEM expressed on CD8(+) T cells promotes survival and memory generation in response to a bacterial infection.

PLoS One 2013 30;8(10):e77992. Epub 2013 Oct 30.

Division of Developmental Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077992PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813523PMC
September 2014

CD8 T cell memory to a viral pathogen requires trans cosignaling between HVEM and BTLA.

PLoS One 2013 29;8(10):e77991. Epub 2013 Oct 29.

Department of Pathology, Immunology & Laboratory Medicine, University of Florida, Gainesville, Florida, United States of America ; La Jolla Institute for Allergy and Immunology, Divisions of Immune Regulation, San Diego, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077991PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812147PMC
September 2014

CD160 activation by herpesvirus entry mediator augments inflammatory cytokine production and cytolytic function by NK cells.

J Immunol 2013 Jul 12;191(2):828-36. Epub 2013 Jun 12.

Infectious and Inflammatory Disease Center, Sanford|Burnham Medical Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.4049/jimmunol.1300894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702646PMC
July 2013

Protein therapeutics targeted at the TNF superfamily.

Authors:
Carl F Ware

Adv Pharmacol 2013 ;66:51-80

Laboratory of Molecular Immunology, Infectious and Inflammatory Diseases Center, Sanford Burnham Medical Research Institute, La Jolla, CA, USA.

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http://dx.doi.org/10.1016/B978-0-12-404717-4.00002-0DOI Listing
August 2013

Lymphotoxin network pathways shape the tumor microenvironment.

Curr Opin Immunol 2013 Apr 20;25(2):222-9. Epub 2013 Jan 20.

Infectious and Inflammatory Diseases Center, Sanford Burnham Medical Research Institute, 10901N. Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.coi.2013.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646954PMC
April 2013

Clinical targeting of the TNF and TNFR superfamilies.

Nat Rev Drug Discov 2013 Feb 21;12(2):147-68. Epub 2013 Jan 21.

Division of Immune Regulation, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nrd3930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625401PMC
February 2013

TRAIL: not just for tumors anymore?

J Exp Med 2012 Oct;209(11):1903-6

the Division of Immune Regulation, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.

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http://dx.doi.org/10.1084/jem.20122235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478931PMC
October 2012

Lymphotoxin-β receptor signaling through NF-κB2-RelB pathway reprograms adipocyte precursors as lymph node stromal cells.

Immunity 2012 Oct 30;37(4):721-34. Epub 2012 Aug 30.

School of Immunity and Infection, IBR-MRC Centre for Immune Regulation, College of Medical and Dental Sciences, University of Birmingham, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S107476131200366
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http://dx.doi.org/10.1016/j.immuni.2012.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809035PMC
October 2012

Infection with Toxoplasma gondii alters lymphotoxin expression associated with changes in splenic architecture.

Infect Immun 2012 Oct 30;80(10):3602-10. Epub 2012 Jul 30.

Department of Pathobiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1128/IAI.00333-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457551PMC
October 2012

Mousing around with caspases and IAPs.

Biochem J 2012 Apr;443(2):e1-2

Programs in Cell Death and Inflammation Research, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1042/BJ20120402DOI Listing
April 2012

Innate B cells: oxymoron or validated concept?

F1000Res 2012 2;1. Epub 2012 Aug 2.

Division of Immune Regulation, La Jolla Institute for Allergy and Immunology, California, 92037, USA.

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http://dx.doi.org/10.12688/f1000research.1-8.v1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751138PMC
December 2013

The role of inflammation in the pathophysiology of depression: different treatments and their effects.

J Rheumatol Suppl 2011 Nov;88:48-54

University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, 3811 O'Hara Street, Pittsburgh, PA 15123, USA.

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http://dx.doi.org/10.3899/jrheum.110903DOI Listing
November 2011

Validity of quality of life measurement tools--from generic to disease-specific.

J Rheumatol Suppl 2011 Nov;88:2-6

Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.3899/jrheum.110906DOI Listing
November 2011

The signaling networks of the herpesvirus entry mediator (TNFRSF14) in immune regulation.

Immunol Rev 2011 Nov;244(1):169-87

Laboratory of Molecular Immunology, Center for Infectious and Inflammatory Diseases, Sanford|Burnham Medical Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1111/j.1600-065X.2011.01064.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381650PMC
November 2011

The TNF receptor super family in immune regulation.

Authors:
Carl F Ware

Immunol Rev 2011 Nov;244(1):5-8

Infectious and Inflammatory Diseases Center, Laboratory of Molecular Immunology, Sanford|Burnham Medical Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1111/j.1600-065X.2011.01065.xDOI Listing
November 2011

Cytokines.

Curr Opin Immunol 2011 Oct;23(5):561-3

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http://dx.doi.org/10.1016/j.coi.2011.09.001DOI Listing
October 2011

TNF Superfamily Networks: bidirectional and interference pathways of the herpesvirus entry mediator (TNFSF14).

Curr Opin Immunol 2011 Oct 13;23(5):627-31. Epub 2011 Sep 13.

Laboratory of Molecular Immunology, Infectious and Inflammatory Diseases Center, Sanford Burnham Medical Research Institute, 10901 N. Torrey Pines Road, La Jolla, CA 92037, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09527915110011
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http://dx.doi.org/10.1016/j.coi.2011.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222271PMC
October 2011

Herpesvirus entry mediator (TNFRSF14) regulates the persistence of T helper memory cell populations.

J Exp Med 2011 Apr 14;208(4):797-809. Epub 2011 Mar 14.

Division of Molecular Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1084/jem.20101562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135347PMC
April 2011

Tumor necrosis factor and anti-tumor necrosis factor therapies.

J Rheumatol Suppl 2010 May;85:27-39

Rebecca MacDonald Centre for Arthritis and Autoimmune Disease and Division of Advanced Therapeutics in Arthritis, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3899/jrheum.091463DOI Listing
May 2010

TNF receptor-1 is required for the formation of splenic compartments during adult, but not embryonic life.

J Immunol 2011 Feb 27;186(3):1486-94. Epub 2010 Dec 27.

Institute of Histology and Embryology, Faculty of Medicine, University of Beograd, 11000 Beograd, Serbia.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1000740
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http://dx.doi.org/10.4049/jimmunol.1000740DOI Listing
February 2011

The canonical and unconventional ligands of the herpesvirus entry mediator.

Adv Exp Med Biol 2011 ;691:353-62

Department of Neurosciences, University of California - San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1007/978-1-4419-6612-4_36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492955PMC
April 2011

Workshop summary: control of lymphocyte function and repertoire by the TNF superfamily.

Adv Exp Med Biol 2011 ;691:351-2

Laboratory of Molecular Immunology, Sanford-Burnham Medical Research Institute, 10901 N. Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1007/978-1-4419-6612-4_35DOI Listing
April 2011

B7-mediated costimulation of CD4 T cells constrains cytomegalovirus persistence.

J Virol 2011 Jan 27;85(1):390-6. Epub 2010 Oct 27.

Division of Developmental Immunology, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1128/JVI.01839-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014178PMC
January 2011

Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8(+) T cells.

Eur J Immunol 2010 Oct;40(10):2762-8

Division of Molecular Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, CA, USA.

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http://dx.doi.org/10.1002/eji.200940256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967573PMC
October 2010

Polymorphic variants of LIGHT (TNF superfamily-14) alter receptor avidity and bioavailability.

J Immunol 2010 Aug 30;185(3):1949-58. Epub 2010 Jun 30.

Division of Molecular Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, CA, USA.

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http://dx.doi.org/10.4049/jimmunol.1001159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921593PMC
August 2010

Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation.

Sci Signal 2010 May 25;3(123):ra41. Epub 2010 May 25.

Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, 609 Charles E. Young Drive East, Los Angeles, CA 90095, USA.

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http://stke.sciencemag.org/cgi/doi/10.1126/scisignal.2000778
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http://dx.doi.org/10.1126/scisignal.2000778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913610PMC
May 2010

Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor.

J Biol Chem 2010 May 26;285(22):17148-55. Epub 2010 Mar 26.

Division of Molecular Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1074/jbc.M110.105874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878066PMC
May 2010

Ontogeny of stromal organizer cells during lymph node development.

J Immunol 2010 Apr 17;184(8):4521-30. Epub 2010 Mar 17.

School of Immunity and Infection, Institute for BioMedical Research-Medical Research Council Centre for Immune Regulation, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0903113
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http://dx.doi.org/10.4049/jimmunol.0903113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862734PMC
April 2010

Targeting the LIGHT-HVEM pathway.

Authors:
Carl F Ware

Adv Exp Med Biol 2009 ;647:146-55

Division of Molecular Immunology, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, California, 92037, USA.

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http://dx.doi.org/10.1007/978-0-387-89520-8_10DOI Listing
June 2010

Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partners.

Semin Immunopathol 2009 Jul 3;31(2):207-21. Epub 2009 Jun 3.

Division of Developmental Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1007/s00281-009-0157-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766922PMC
July 2009

LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen.

J Immunol 2009 May;182(9):5439-45

Department of Molecular Cell Biology and Immunology, VU (Vrije Universiteit) University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.0801165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703443PMC
May 2009

Unconventional ligand activation of herpesvirus entry mediator signals cell survival.

Proc Natl Acad Sci U S A 2009 Apr 30;106(15):6244-9. Epub 2009 Mar 30.

Divisions of Molecular Immunology and Developmental Immunology, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0902115106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669392PMC
April 2009

Vascular endothelial growth factor promotes macrophage apoptosis through stimulation of tumor necrosis factor superfamily member 14 (TNFSF14/LIGHT).

Wound Repair Regen 2008 Sep-Oct;16(5):602-14

Department of Cell Biology and Neuroscience, University of California-Riverside, 900 University Ave., Riverside, CA 92521, USA.

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http://dx.doi.org/10.1111/j.1524-475X.2008.00411.xDOI Listing
May 2009

Cross-regulation between herpesviruses and the TNF superfamily members.

Nat Rev Immunol 2008 Nov;8(11):861-73

Division of Molecular Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nri2434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665163PMC
November 2008

Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways.

Authors:
Carl F Ware

Immunol Rev 2008 Jun;223:186-201

Division of Molecular Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1111/j.1600-065X.2008.00629.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613484PMC
June 2008

The TNF Superfamily-2008.

Authors:
Carl F Ware

Cytokine Growth Factor Rev 2008 Jun-Aug;19(3-4):183-6

Division of Molecular Immunology, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, United States.

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http://dx.doi.org/10.1016/j.cytogfr.2008.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646499PMC
September 2008

A crucial role for HVEM and BTLA in preventing intestinal inflammation.

J Exp Med 2008 Jun 2;205(6):1463-76. Epub 2008 Jun 2.

Division of Developmental Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1084/jem.20071160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413041PMC
June 2008

The TNF receptor and Ig superfamily members form an integrated signaling circuit controlling dendritic cell homeostasis.

Cytokine Growth Factor Rev 2008 Jun-Aug;19(3-4):277-84. Epub 2008 Jun 3.

Laboratory of Parasitology, Erasme, Université Libre de Bruxelles, 808 Route de Lennik, 1070 Bruxelles, Belgium.

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http://linkinghub.elsevier.com/retrieve/pii/S135961010800046
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http://dx.doi.org/10.1016/j.cytogfr.2008.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581770PMC
September 2008

ICOS, CD40, and lymphotoxin beta receptors signal sequentially and interdependently to initiate a germinal center reaction.

J Immunol 2008 Feb;180(4):2284-93

Department of Immunology, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735203PMC
http://dx.doi.org/10.4049/jimmunol.180.4.2284DOI Listing
February 2008

Structural determinants of herpesvirus entry mediator recognition by murine B and T lymphocyte attenuator.

J Immunol 2008 Jan;180(2):940-7

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.4049/jimmunol.180.2.940DOI Listing
January 2008

Alternative entry receptors for herpes simplex virus and their roles in disease.

Cell Host Microbe 2007 Jul;2(1):19-28

Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.chom.2007.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2083283PMC
July 2007

OX40 costimulation promotes persistence of cytomegalovirus-specific CD8 T Cells: A CD4-dependent mechanism.

J Immunol 2007 Aug;179(4):2195-202

Division of Molecular Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.4049/jimmunol.179.4.2195DOI Listing
August 2007

SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling.

J Clin Invest 2007 Aug;117(8):2164-75

Division of Cell Biology, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1172/JCI31640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1924495PMC
August 2007

The LT beta R signaling pathway.

Adv Exp Med Biol 2007 ;597:160-72

Division of Molecular Immunology, La Jolla Institute for Allergy and Immunology, San Diego, California 92121, USA.

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http://dx.doi.org/10.1007/978-0-387-70630-6_13DOI Listing
August 2007