Carl L Hansen

Carl L Hansen

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Carl L Hansen

Carl L Hansen

Publications by authors named "Carl L Hansen"

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34Publications

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Highly multiplexed single-cell quantitative PCR.

PLoS One 2018 29;13(1):e0191601. Epub 2018 Jan 29.

Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0191601PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788347PMC
March 2018

Scalable whole-genome single-cell library preparation without preamplification.

Nat Methods 2017 02 9;14(2):167-173. Epub 2017 Jan 9.

Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.

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http://www.nature.com/articles/nmeth.4140
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http://dx.doi.org/10.1038/nmeth.4140DOI Listing
February 2017

Robust high-performance nanoliter-volume single-cell multiple displacement amplification on planar substrates.

Proc Natl Acad Sci U S A 2016 07 13;113(30):8484-9. Epub 2016 Jul 13.

Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada V6T 1Z4; Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada V6T 1Z4

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http://dx.doi.org/10.1073/pnas.1520964113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968760PMC
July 2016

Clonal analysis of individual human embryonic stem cell differentiation patterns in microfluidic cultures.

Biotechnol J 2015 Oct 16;10(10):1546-54. Epub 2015 Jul 16.

Centre for High-Throughput Biology, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/biot.201500035DOI Listing
October 2015

Methods for multiplex template sampling in digital PCR assays.

PLoS One 2014 22;9(5):e98341. Epub 2014 May 22.

Centre for High-Throughput Biology, University of British Columbia, Vancouver, British Columbia, Canada; Department of Physics and Astronomy, University of British Columbia, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098341PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031183PMC
January 2015

Dissecting genealogy and cell cycle as sources of cell-to-cell variability in MAPK signaling using high-throughput lineage tracking.

Proc Natl Acad Sci U S A 2013 Jul 26;110(28):11403-8. Epub 2013 Jun 26.

Centre for High-Throughput Biology and Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada V6T 1Z4.

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http://dx.doi.org/10.1073/pnas.1215850110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710830PMC
July 2013

Microfluidic integration of parallel solid-phase liquid chromatography.

Anal Chem 2013 Mar 22;85(5):2999-3005. Epub 2013 Feb 22.

Centre for High-Throughput Biology, University of British Columbia, Vancouver BC, Canada.

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http://dx.doi.org/10.1021/ac400163uDOI Listing
March 2013

Fabrication of high-quality microfluidic solid-phase chromatography columns.

Anal Chem 2013 Feb 10;85(3):1797-802. Epub 2013 Jan 10.

Centre for High-Throughput Biology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1021/ac303153aDOI Listing
February 2013

Purification and quantitation of bacteriophage M13 using desalting spin columns and digital PCR.

J Virol Methods 2012 Oct 2;185(1):171-4. Epub 2012 Jul 2.

Centre for High-Throughput Biology, University of British Columbia, 2125 East Mall, Vancouver, BC, V6T 1Z4 Canada.

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http://dx.doi.org/10.1016/j.jviromet.2012.06.021DOI Listing
October 2012

Microfluidic single cell analysis: from promise to practice.

Curr Opin Chem Biol 2012 Aug 21;16(3-4):381-90. Epub 2012 Apr 21.

Centre for High-Throughput Biology, University of British Columbia, 2185 East Mall, Vancouver, British Columbia, V6T 1Z4, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S13675931120005
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http://dx.doi.org/10.1016/j.cbpa.2012.03.022DOI Listing
August 2012

Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA.

Mol Ther Nucleic Acids 2012 Aug 14;1:e37. Epub 2012 Aug 14.

1] Precision Nanosystems, Vancouver, British Columbia, Canada [2] Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/mtna.2012.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442367PMC
August 2012

A programmable droplet-based microfluidic device applied to multiparameter analysis of single microbes and microbial communities.

Proc Natl Acad Sci U S A 2012 May 30;109(20):7665-70. Epub 2012 Apr 30.

Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC, Canada, V6T 1Z4.

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http://dx.doi.org/10.1073/pnas.1106752109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356603PMC
May 2012

Should genetic testing go digital?

Expert Rev Mol Diagn 2012 Mar;12(2):111-4

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http://dx.doi.org/10.1586/erm.12.6DOI Listing
March 2012

Parylene C coating for high-performance replica molding.

Lab Chip 2011 Dec 13;11(23):4122-5. Epub 2011 Oct 13.

Centre for High-Throughput Biology, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1039/c1lc20623kDOI Listing
December 2011

High-throughput microfluidic single-cell RT-qPCR.

Proc Natl Acad Sci U S A 2011 Aug 1;108(34):13999-4004. Epub 2011 Aug 1.

Centre for High-Throughput Biology, University of British Columbia, Vancouver, BC, Canada V6T 1Z4.

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http://dx.doi.org/10.1073/pnas.1019446108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161570PMC
August 2011

Megapixel digital PCR.

Nat Methods 2011 Jul 3;8(8):649-51. Epub 2011 Jul 3.

Centre for High-Throughput Biology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/nmeth.1640DOI Listing
July 2011

MicroRNA-146a disrupts hematopoietic differentiation and survival.

Exp Hematol 2011 Feb 7;39(2):167-178.e4. Epub 2010 Oct 7.

British Columbia Cancer Agency Research Centre, 675 West 10th Avenue, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.exphem.2010.09.011DOI Listing
February 2011

Probing the complexity of miRNA expression across hematopoiesis.

Cell Cycle 2011 Jan 1;10(1):2-3. Epub 2011 Jan 1.

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http://dx.doi.org/10.4161/cc.10.1.14289DOI Listing
January 2011

Microfluidic measurement of antibody-antigen binding kinetics from low-abundance samples and single cells.

Anal Chem 2010 Oct;82(20):8671-9

Department of Chemical and Biological Engineering, University of British Columbia, 2360 East Mall, Vancouver, British Columbia, Canada V6T 1Z3.

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http://dx.doi.org/10.1021/ac101956eDOI Listing
October 2010

Three-dimensional large-scale microfluidic integration by laser ablation of interlayer connections.

Lab Chip 2010 Sep 11;10(18):2358-65. Epub 2010 Jun 11.

Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1039/c004051gDOI Listing
September 2010

A microfluidic device for multiplexed protein detection in nano-liter volumes.

Anal Biochem 2009 Mar 24;386(1):30-5. Epub 2008 Dec 24.

Institute for Systems Biology, Seattle, WA 98103, USA.

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http://dx.doi.org/10.1016/j.ab.2008.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678059PMC
March 2009

A complete microfluidic screening platform for rational protein crystallization.

J Am Chem Soc 2007 Jan;129(3):454-5

Department of Physics and Astronomy, University of British Columbia, 6224 Agricultural Road, Vancouver, British Columbia V6T 1Z1, Canada.

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http://dx.doi.org/10.1021/ja065855bDOI Listing
January 2007

Phase knowledge enables rational screens for protein crystallization.

Proc Natl Acad Sci U S A 2006 Nov 30;103(45):16746-51. Epub 2006 Oct 30.

Department of Biochemistry and Molecular Biophysics, California Institute of Technology, MS 128-95, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.0605293103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636526PMC
November 2006

A microfluidic device for kinetic optimization of protein crystallization and in situ structure determination.

J Am Chem Soc 2006 Mar;128(10):3142-3

Department of Applied Physics, California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ja0576637DOI Listing
March 2006

Long-term monitoring of bacteria undergoing programmed population control in a microchemostat.

Science 2005 Jul;309(5731):137-40

Department of Applied Physics, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1126/science.1109173DOI Listing
July 2005

Systematic investigation of protein phase behavior with a microfluidic formulator.

Proc Natl Acad Sci U S A 2004 Oct 27;101(40):14431-6. Epub 2004 Sep 27.

Department of Applied Physics, California Institute of Technology, MS 128-95, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.0405847101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC521965PMC
October 2004

A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion.

Proc Natl Acad Sci U S A 2002 Dec 16;99(26):16531-6. Epub 2002 Dec 16.

Department of Applied Physics, California Institute of Technology, MS 128-95, Pasadena, CA 91125, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.262485199
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http://dx.doi.org/10.1073/pnas.262485199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC139178PMC
December 2002