Publications by authors named "Carl Clarke"

71Publications

Initiating pharmacotherapy in early Parkinson's disease.

Lancet Neurol 2020 08;19(8):643-644

Edmond J Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology, University of Toronto, Toronto, ON M5T 2S8, Canada.

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http://dx.doi.org/10.1016/S1474-4422(20)30225-8DOI Listing
August 2020

Initiation of pharmacological therapy in Parkinson's disease: when, why, and how.

Lancet Neurol 2020 05 12;19(5):452-461. Epub 2020 Mar 12.

Edmond J Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(20)30036-3DOI Listing
May 2020

The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population-Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight.

Authors:
Sara Bandres-Ciga Sarah Ahmed Marya S Sabir Cornelis Blauwendraat Astrid D Adarmes-Gómez Inmaculada Bernal-Bernal Marta Bonilla-Toribio Dolores Buiza-Rueda Fátima Carrillo Mario Carrión-Claro Pilar Gómez-Garre Silvia Jesús Miguel A Labrador-Espinosa Daniel Macias Carlota Méndez-Del-Barrio Teresa Periñán-Tocino Cristina Tejera-Parrado Laura Vargas-González Monica Diez-Fairen Ignacio Alvarez Juan Pablo Tartari Mariateresa Buongiorno Miquel Aguilar Ana Gorostidi Jesús Alberto Bergareche Elisabet Mondragon Ana Vinagre-Aragon Ioana Croitoru Javier Ruiz-Martínez Oriol Dols-Icardo Jaime Kulisevsky Juan Marín-Lahoz Javier Pagonabarraga Berta Pascual-Sedano Mario Ezquerra Ana Cámara Yaroslau Compta Manel Fernández Rubén Fernández-Santiago Esteban Muñoz Eduard Tolosa Francesc Valldeoriola Isabel Gonzalez-Aramburu Antonio Sanchez Rodriguez María Sierra Manuel Menéndez-González Marta Blazquez Ciara Garcia Esther Suarez-San Martin Pedro García-Ruiz Juan Carlos Martínez-Castrillo Lydia Vela-Desojo Clara Ruz Francisco Javier Barrero Francisco Escamilla-Sevilla Adolfo Mínguez-Castellanos Debora Cerdan Cesar Tabernero Maria Jose Gomez Heredia Francisco Perez Errazquin Manolo Romero-Acebal Cici Feliz Jose Luis Lopez-Sendon Marina Mata Irene Martínez Torres Jonggeol Jeffrey Kim Clifton L Dalgard Janet Brooks Sara Saez-Atienzar J Raphael Gibbs Rafael Jorda Juan A Botia Luis Bonet-Ponce Karen E Morrison Carl Clarke Manuela Tan Huw Morris Connor Edsall Dena Hernandez Javier Simon-Sanchez Mike A Nalls Sonja W Scholz Adriano Jimenez-Escrig Jacinto Duarte Francisco Vives Raquel Duran Janet Hoenicka Victoria Alvarez Jon Infante Maria José Marti Jordi Clarimón Adolfo López de Munain Pau Pastor Pablo Mir Andrew Singleton

Mov Disord 2019 12 29;34(12):1851-1863. Epub 2019 Oct 29.

Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1002/mds.27864DOI Listing
December 2019

Cochrane systematic review and meta-analysis of botulinum toxin for the prevention of migraine.

BMJ Open 2019 07 16;9(7):e027953. Epub 2019 Jul 16.

University of Birmingham, Institute of Metabolism and Systems Research, Birmingham, UK.

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http://dx.doi.org/10.1136/bmjopen-2018-027953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661560PMC
July 2019

Botulinum toxins for the prevention of migraine in adults.

Cochrane Database Syst Rev 2018 06 25;6:CD011616. Epub 2018 Jun 25.

Institute of Applied Health Research, University of Birmingham, Edgbaston, Birmingham, UK, B15 2TT.

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http://dx.doi.org/10.1002/14651858.CD011616.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513576PMC
June 2018

Corrigendum to "Subjective Experiences of Speech and Language Therapy in Patients with Parkinson's Disease: A Pilot Study".

Rehabil Res Pract 2016 17;2016:1654282. Epub 2016 Aug 17.

Division of Health and Social Care, Faculty of Life Sciences and Medicine, King's College, 7th Floor Capital House, 42 Weston Street, London SE1 3QD, UK.

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http://dx.doi.org/10.1155/2016/1654282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005817PMC
September 2016

Physiotherapy and Occupational Therapy and Mild to Moderate Parkinson Disease-Reply.

JAMA Neurol 2016 07;73(7):894-5

King's College London, London, England.

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http://dx.doi.org/10.1001/jamaneurol.2016.1283DOI Listing
July 2016

A global portrait of the manganese industry-A socioeconomic perspective.

Neurotoxicology 2017 01 13;58:173-179. Epub 2016 May 13.

Risk & Policy Analysts Ltd., Farthing Green House, 1 Beccles Road, Loddon, Norfolk NR14 6LT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neuro.2016.03.013DOI Listing
January 2017

Authors' reply to Braithwaite and Elrington.

BMJ 2015 Nov 3;351:h5846. Epub 2015 Nov 3.

School of Clinical and Experimental Medicine, College of Medicine and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1136/bmj.h5846DOI Listing
November 2015

Initial drug treatment in Parkinson's disease.

BMJ 2015 Sep 18;351:h4669. Epub 2015 Sep 18.

School of Clinical and Experimental Medicine, College of Medicine and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK Department of Neurology, Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Birmingham.

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http://dx.doi.org/10.1136/bmj.h4669DOI Listing
September 2015

Comparing results from long and short form versions of the Parkinson's disease questionnaire in a longitudinal study.

Parkinsonism Relat Disord 2015 Nov 3;21(11):1312-6. Epub 2015 Sep 3.

Department of Neurology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

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http://dx.doi.org/10.1016/j.parkreldis.2015.09.008DOI Listing
November 2015

Subjective Experiences of Speech and Language Therapy in Patients with Parkinson's Disease: A Pilot Study.

Rehabil Res Pract 2015 8;2015:839895. Epub 2015 Jul 8.

Division of Health and Social Care, Faculty of Life Sciences and Medicine, King's College, 7th Floor Capital House, 42 Weston Street, London SE1 3QD, UK.

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http://dx.doi.org/10.1155/2015/839895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510263PMC
August 2015

Measuring the burden and mortality of hospitalisation in Parkinson's disease: A cross-sectional analysis of the English Hospital Episodes Statistics database 2009-2013.

Parkinsonism Relat Disord 2015 May 17;21(5):449-54. Epub 2015 Feb 17.

School of Clinical and Experimental Medicine, College of Medicine and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK; Department of Neurology, Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Birmingham B18 7QH, UK. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2015.01.017DOI Listing
May 2015

The effects of two polymorphisms on p21cip1 function and their association with Alzheimer's disease in a population of European descent.

PLoS One 2015 27;10(1):e0114050. Epub 2015 Jan 27.

Neuropharmacology and Neurobiology, College of Medical and Dental Sciences, School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, B15 2TT, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114050PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308198PMC
January 2016

Systematic review and meta-analysis of hydrocarbon exposure and the risk of Parkinson's disease.

Parkinsonism Relat Disord 2015 Mar 26;21(3):243-8. Epub 2014 Dec 26.

School of Clinical and Experimental Medicine, College of Medicine and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, UK; Department of Neurology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2014.12.017DOI Listing
March 2015

Physiotherapy for Parkinson's disease: a comparison of techniques.

Cochrane Database Syst Rev 2014 Jun 17(6):CD002815. Epub 2014 Jun 17.

Birmingham Clinical Trials Unit, University of Birmingham, Robert Aitken Institute, Edgbaston, Birmingham, UK, B15 2TT.

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http://dx.doi.org/10.1002/14651858.CD002815.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120367PMC
June 2014

Physiotherapy versus placebo or no intervention in Parkinson's disease.

Cochrane Database Syst Rev 2013 Sep 10(9):CD002817. Epub 2013 Sep 10.

Birmingham Clinical Trials Unit, University of Birmingham, Robert Aitken Institute, Edgbaston, Birmingham, UK, B15 2TT.

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http://dx.doi.org/10.1002/14651858.CD002817.pub4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120224PMC
September 2013

A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants.

J Med Genet 2012 Nov;49(11):721-6

Department. of Neurodegenerative diseases, Hertie-Institute for Clinical Brain Research and DZNE- German Center for Neurodegenerative Diseases, Tübingen, Hoppe-Seyler-Str. 3, Tübingen 72076, Germany.

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http://dx.doi.org/10.1136/jmedgenet-2012-101155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488700PMC
November 2012

Physiotherapy versus placebo or no intervention in Parkinson's disease.

Cochrane Database Syst Rev 2012 Aug 15(8):CD002817. Epub 2012 Aug 15.

Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1002/14651858.CD002817.pub3DOI Listing
August 2012

Comparison of speech and language therapy techniques for speech problems in Parkinson's disease.

Cochrane Database Syst Rev 2012 Aug 15(8):CD002814. Epub 2012 Aug 15.

School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, Birmingham, UK.

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http://dx.doi.org/10.1002/14651858.CD002814.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120320PMC
August 2012

Speech and language therapy versus placebo or no intervention for speech problems in Parkinson's disease.

Cochrane Database Syst Rev 2012 Aug 15(8):CD002812. Epub 2012 Aug 15.

School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, Birmingham, UK.

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http://dx.doi.org/10.1002/14651858.CD002812.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098084PMC
August 2012

Physiotherapy versus placebo or no intervention in Parkinson's disease.

Cochrane Database Syst Rev 2012 Jul 11(7):CD002817. Epub 2012 Jul 11.

Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1002/14651858.CD002817.pub2DOI Listing
July 2012

Rating papilloedema: an evaluation of the Frisén classification in idiopathic intracranial hypertension.

J Neurol 2012 Jul 12;259(7):1406-12. Epub 2012 Jan 12.

School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1007/s00415-011-6365-6DOI Listing
July 2012

Anti-hypertensive drugs as disease-modifying agents for Parkinson's disease: evidence from observational studies and clinical trials.

Cochrane Database Syst Rev 2011 Nov 9(11):CD008535. Epub 2011 Nov 9.

Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK.

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http://dx.doi.org/10.1002/14651858.CD008535.pub2DOI Listing
November 2011

Non-steroidal anti-inflammatory drugs as disease-modifying agents for Parkinson's disease: evidence from observational studies.

Cochrane Database Syst Rev 2011 Nov 9(11):CD008454. Epub 2011 Nov 9.

Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK.

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http://dx.doi.org/10.1002/14651858.CD008454.pub2DOI Listing
November 2011

Helicobacter pylori eradication for Parkinson's disease.

Cochrane Database Syst Rev 2011 Nov 9(11):CD008453. Epub 2011 Nov 9.

1Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK.

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http://dx.doi.org/10.1002/14651858.CD008453.pub2DOI Listing
November 2011

Should treatment for Parkinson's disease start immediately on diagnosis or delayed until functional disability develops?

Mov Disord 2011 Jun 14;26(7):1187-93. Epub 2011 Apr 14.

Department of Neurology, City Hospital, Sandwell and West Birmingham NHS Trust, Dudley Road, Birmingham, United Kingdom.

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http://dx.doi.org/10.1002/mds.23519DOI Listing
June 2011

Meta-analysis of the comparative efficacy and safety of adjuvant treatment to levodopa in later Parkinson's disease.

Mov Disord 2011 Mar 2;26(4):587-98. Epub 2011 Mar 2.

Birmingham Clinical Trials Unit, College of Medical & Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

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http://dx.doi.org/10.1002/mds.23517DOI Listing
March 2011

A randomised controlled trial of treatment for idiopathic intracranial hypertension.

J Neurol 2011 May 16;258(5):874-81. Epub 2010 Dec 16.

Department of Neurology, School of Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1007/s00415-010-5861-4DOI Listing
May 2011

Systematic review of levodopa dose equivalency reporting in Parkinson's disease.

Mov Disord 2010 Nov;25(15):2649-53

Birmingham Clinical Trials Unit, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

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http://dx.doi.org/10.1002/mds.23429DOI Listing
November 2010

Evaluation of the efficacy and safety of adjuvant treatment to levodopa therapy in Parkinson s disease patients with motor complications.

Cochrane Database Syst Rev 2010 Jul 7(7):CD007166. Epub 2010 Jul 7.

Birmingham Clinical Trials Unit, University of Birmingham, Edgbaston, Birmingham, UK, B15 2TT.

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http://dx.doi.org/10.1002/14651858.CD007166.pub2DOI Listing
July 2010

Cannabinoids for Tourette's Syndrome.

Cochrane Database Syst Rev 2009 Oct 7(4):CD006565. Epub 2009 Oct 7.

Neuropsychiatry, Birmingham and Solihull Mental Health Trust, Birmingham, UK.

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http://dx.doi.org/10.1002/14651858.CD006565.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387115PMC
October 2009

Systematic review of apomorphine infusion, levodopa infusion and deep brain stimulation in advanced Parkinson's disease.

Parkinsonism Relat Disord 2009 Dec 4;15(10):728-41. Epub 2009 Oct 4.

Department of Neurology, City Hospital, Birmingham, UK.

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http://dx.doi.org/10.1016/j.parkreldis.2009.09.005DOI Listing
December 2009

Exploring the pathogenesis of IIH: an inflammatory perspective.

J Neuroimmunol 2008 Sep 3;201-202:212-20. Epub 2008 Aug 3.

Academic Unit of Ophthalmology, School of Immunology, Infection and Inflammation, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, United Kingdom.

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http://dx.doi.org/10.1016/j.jneuroim.2008.06.029DOI Listing
September 2008

Are delayed-start design trials to show neuroprotection in Parkinson's disease fundamentally flawed?

Authors:
Carl E Clarke

Mov Disord 2008 Apr;23(6):784-9

Department of Neurology, City Hospital, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, United Kingdom.

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http://dx.doi.org/10.1002/mds.21918DOI Listing
April 2008

Rotigotine transdermal patch in early Parkinson's disease: a randomized, double-blind, controlled study versus placebo and ropinirole.

Mov Disord 2007 Dec;22(16):2398-404

Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1002/mds.21741DOI Listing
December 2007

Parkinson's disease.

Am Fam Physician 2007 Apr;75(7):1045-8

University of Birmingham, Birmingham, United Kingdom.

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April 2007

Parkinson's disease.

BMJ Clin Evid 2007 Aug 1;2007. Epub 2007 Aug 1.

University of Birmingham, Birmingham, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943804PMC
August 2007

Development of dyskinesias in a 5-year trial of ropinirole and L-dopa.

Mov Disord 2006 Nov;21(11):1844-50

Clinical Investigation Centre, Department of Pharmacology and INSERM U455, Toulouse Hospital, Toulouse, France.

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http://doi.wiley.com/10.1002/mds.20988
Publisher Site
http://dx.doi.org/10.1002/mds.20988DOI Listing
November 2006

Idiopathic intracranial hypertension.

Lancet Neurol 2006 May;5(5):433-42

University of Birmingham, Department of Neurology, City Hospital, Birmingham B18 7QH, UK.

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http://dx.doi.org/10.1016/S1474-4422(06)70442-2DOI Listing
May 2006

Parkinson's disease.

Clin Evid 2005 Jun(13):1658-77

University of Birmingham, Birmingham, UK.

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June 2005

Rasagiline for motor complications in Parkinson's disease.

Authors:
Carl E Clarke

Lancet 2005 Mar 12-18;365(9463):914-6

University of Birmingham and Department of Neurology, City Hospital, Birmingham B18 7QH, UK.

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http://dx.doi.org/10.1016/S0140-6736(05)71056-4DOI Listing
April 2005

Parkinson's disease.

Clin Evid 2004 Jun(11):1736-54

University of Birmingham, Birmingham, UK.

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June 2004

Parkinson's disease.

Clin Evid 2003 Dec(10):1582-98

University of Birmingham, Birmingham, UK.

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December 2003

Neuroprotection and pharmacotherapy for motor symptoms in Parkinson's disease.

Authors:
Carl E Clarke

Lancet Neurol 2004 Aug;3(8):466-74

University of Birmingham, UK.

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http://dx.doi.org/10.1016/S1474-4422(04)00823-3DOI Listing
August 2004

Pregnancy in stiff-limb syndrome.

Mov Disord 2004 Jul;19(7):852-854

Department of Neurology, City Hospital, Birmingham, United Kingdom.

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http://dx.doi.org/10.1002/mds.20094DOI Listing
July 2004

Cabergoline versus levodopa monotherapy.

Mov Disord 2004 Jun;19(6):733-4; author reply 734-5

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http://dx.doi.org/10.1002/mds.20032DOI Listing
June 2004

A "cure" for Parkinson's disease: can neuroprotection be proven with current trial designs?

Authors:
Carl E Clarke

Mov Disord 2004 May;19(5):491-8

Reader in Clinical Neurology, Division of Neuroscience, University of Birmingham and City Hospital, Birmingham, United Kingdom.

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http://dx.doi.org/10.1002/mds.20057DOI Listing
May 2004

An English kindred with a novel recessive tauopathy and respiratory failure.

Ann Neurol 2003 Nov;54(5):682-6

Department of Neurology, City Hospital, University of Birmingham, Birmingham B18 7QH, UK.

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http://dx.doi.org/10.1002/ana.10747DOI Listing
November 2003

Parkinson's disease.

Authors:
Carl Clarke A Moore

Clin Evid 2002 Dec(8):1370-85

University of Birmingham, Birmingham, UK.

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December 2002

Systematic review of paramedical therapies for Parkinson's disease.

Mov Disord 2002 Sep;17(5):984-91

Department of Neurology, City Hospital NHS Trust, and The University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1002/mds.10197DOI Listing
September 2002

Parkinson's disease.

Clin Evid 2002 Jun(7):1208-20

University of Birmingham, Birmingham, UK.

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June 2002

Evaluating drug treatments for Parkinson's disease: how good are the trials?

BMJ 2002 Jun;324(7352):1508-11

Birmingham Clinical Trials Unit, University of Birmingham, Birmingham B15 2RR, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1123447PMC
http://dx.doi.org/10.1136/bmj.324.7352.1508DOI Listing
June 2002